Cancer Communications
Primary intrathoracic liposarcoma: a clinical analysis of 31 cases
- Zhixue Fu†,
- Kun Yang†,
- Xu Yang,
- Shulan Chen,
- Wenqing Wang,
- Dongfu Chen,
- Jun Zhao,
- Zhishan Li,
- Qinfu Feng,
- Zongmei Zhou,
- Luhua Wang,
- Shugeng Gao and
- Jun Liang
†Contributed equally
- Received: 29 August 2018
- Accepted: 19 March 2019
- Published: 2 April 2019
Dear Editor,
Liposarcoma is a common soft tissue malignancy in adults. It most commonly occurs in the deep soft tissue of the extremities and retroperitoneum. Primary intrathoracic liposarcoma is rare, represents 2.7% of all liposarcomas [1]. According to the distinct tumor locations, it can be divided into mediastinal, pleural, and pulmonary liposarcomas. Most literature has reviewed the clinicopathological or molecular cytogenetic characteristics of mediastinal and thoracic liposarcomas [2, 3]. However, intrathoracic liposarcoma is poorly documented because of its rarity. Complete surgical resection is thought to be the best treatment for primary intrathoracic liposarcoma, but the impact of radiotherapy and systemic therapy remains unclear. Therefore, we analyzed the clinicopathological data of 31 patients with primary intrathoracic liposarcoma who were treated in the Cancer Hospital of Chinese Academy of Medical Sciences between October 1970 and July 2015 to explore their clinicopathologic features and treatment outcomes (Additional file 1: Table S1).
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