domingo, 31 de diciembre de 2023

Breast cancer screening: one size does not fit all The Lancet Oncology

Global, regional, and national burden of other musculoskeletal disorders, 1990–2020, and projections to 2050: a systematic analysis of the Global Burden of Disease Study 2021 GBD 2021 Other Musculoskeletal Disorders Collaborators

Burden and risk factors of chronic obstructive pulmonary disease in Sub-Saharan African countries, 1990–2019: a systematic analysis for the Global Burden of disease study 2019

Peripheral artery disease: a global need for detection, prevention, and treatment Lars Norgren

Global, regional, and national burden of rheumatoid arthritis, 1990–2020, and projections to 2050: a systematic analysis of the Global Burden of Disease Study 2021 GBD 2021 Rheumatoid Arthritis Collaborators

World Journal of Surgical Oncology

Health Benefits and Functions of Ethnic Foods focusing on Fermented Foods

Pathways from media attention and peer communication to body dissatisfaction: the moderating role of protective filtering

Context Matters: Environmental Influences on Eating disorders, Disordered eating and Body Image

Psychometric properties of self-report measures of eating disorder cognitions: a systematic review Authors:Amaani H. Hatoum, Amy L. Burton, Sophie L. Berry and Maree J. Abbott

Epistaxis and Hypertension: Reviewing a Complex Relationship Paolo Spriano

The New Blood Pressure Target in Primary Care Neil Skolnik, MD

Triple Agonist Retatrutide Hits New Weight-Loss Highs Mitchel L. Zoler, PhD

What Is the Link Between Cellphones and Male Fertility? Philippe Tellier, MD

SCD in Athletes: Lessons From High-Profile Cases Robert A. Harrington, MD; Manesh R. Patel, MD

sábado, 30 de diciembre de 2023

Mettl3 guides CD8 T cells to eliminate infected cells with maximum efficiency

"NK cell-engaging nanodrones" can selectively target and kill cancer cells

It's coming... a hug of souls to all... we deserve it

Thanks to readers from all over the world

Thank you to everyone who reads me, silently... thanks to everyone who follows me every day... thanks to all countries... Estados Unidos Suecia Alemania Singapur Reino Unido Corea del Sur Irán Francia Hong Kong Camboya Canadá Finlandia España Australia Colombia Afganistán Irlanda Rusia China Otros

Light Activity in Childhood May Lower Cholesterol Antara Ghosh

Short Course of Amoxicillin Shows Effectiveness for Febrile UTIs Heidi Splete

Conjunctivitis: How Common Is It in Patients on Dupilumab for AD? Doug Brunk

Who Is Helped by AI Use During Colonoscopy? Marilynn Larkin

Beetroot Juice Improves Fitness and Function in Patients With COPD Heidi Splete

New on NCI’s Websites for December 2023 W. Kimryn Rathmell Begins Work as 17th Director of the National Cancer Institute

New Findings About Key Pathological Protein in Parkinson’s Disease Open Paths to Novel Therapies

Don’t miss the National Eye Institute’s upcoming Visual NeuroPlasticity Workshop Wednesday, January 10, 2024,

U.S. - Ireland R&D Partnership hosts workshop

NEI posts executive summary of workshop on extracellular vesicles

Study Identifies "Visual System" Protein for Circadian Rhythm Stability

viernes, 29 de diciembre de 2023

Advanced MRI hopes to improve outcomes for Fontan cardiac patients


Blue Light Exposure: Unveiling the Effects By Ivanhoe Broadcast News on January 7, 2024


Alexandra’s Art Funds Research By Ivanhoe Broadcast News on January 7, 2024


Seniors Battling Anxiety in Silence By Ivanhoe Broadcast News on January 6, 2024


Chronic Pain, Inflammation and Dementia Link By Ivanhoe Broadcast News on January 6, 2024


Healing Toothpaste: Hydroxyapatite to The Rescue By Ivanhoe Broadcast News on January 5, 2024


New Kind of Classroom for Sick Kids By Ivanhoe Broadcast News on January 4, 2024


Plan B for Statin-Intolerant Patients By Ivanhoe Broadcast News on January 3, 2024


Are Naps Really Beneficial? By Ivanhoe Broadcast News on January 2, 2024


Hospital to Home: Nurses Help Navigate Their Patients’ Recovery By Ivanhoe Broadcast News on January 1, 2024

Extracranial Surgery Soon After TBI Tied to Poorer Outcomes Kelli Whitlock Burton

tDCS Promising for Improved Cognition in Alzheimer's Megan Brooks

Sharp Rise in US Suicide Rates Especially in Indigenous People, White Men Eve Bender

No Added Benefit From Chemo in This Breast Cancer Subtype Liam Davenport

Regular Physical Activity Linked to Larger Brain Volume Megan Brooks

'World's Healthiest Arteries' Found to Be the Most Elastic Matías A. Loewy

Specific Personality Traits May Influence Dementia Risk Megan Brooks

Neuroinflammation and Alzheimer's disease poster

Know the Science: Complementary and Integrative Health Resources From NCCIH Complementary and Integrative Health Resources From NCCIH Herbs at a Glance Alerts and Advisories Connect With Us: Email Updates and Social Media

Hypothermia | Home Test to Treat | Coal Pollution Deaths | Holiday Drinking | Mental Health Research

jueves, 28 de diciembre de 2023

Post-conization surveillance in an organized cervical screening program with more than 23,000 years of follow-up

Experiences of patients and family members with follow-up care, information needs and provider support after identification of Lynch Syndrome

The classification of obesity based on metabolic status redefines the readmission of non-Hodgkin’s lymphoma—an observational study

Association between allostatic load and breast cancer risk: a cohort study

Orphanet Journal of Rare Diseases

Highlights in HR-Positive Breast Cancer From SABCS 2023 Harold J. Burstein, MD, PhD

Benzodiazepines Linked to Higher Miscarriage Risk in Early Pregnancy Lara Salahi

Positive Topline Results for SEQUOIA-HCM Trial in OHCM Susan Jeffrey

Elafibranor Appears Effective, Safe for Primary Biliary Cholangitis Carolyn Crist

Building a Toolkit for the Treatment of Acute Migraine Sue Hughes

Top Cancer Currents Stories of 2023

Complementary Psychological and/or Physical Approaches for Cancer Symptoms and Treatment Side Effects

When and How To Contact NCCIH Program Directors for Help

Don’t call me “old”: Avoiding ageism when writing about aging Ageist messages are everywhere — you need only to browse a greeting card aisle to see countless quips about being a “geezer” or “over the hill.” Ageist content is so prevalent in our society that too many people may not recognize it as problematic. Well-intentioned writers can sometimes inadvertently reinforce harmful stereotypes about older adults. Whether you’re writing a blog post, grant application, or journal article, here are some tips and resources to help your audience think more positively about aging.

In Mouse Study, KRAS-Targeted Drug Shows Potential against Pancreatic Cancer Progress continues in targeting a hard-to-hit cancer protein KRAS has been one of the most hard-to-hit targets in cancer research. But over the past 2 years, two new drugs, sotorasib (Lumakras) and adagrasib (Krazati), have been approved to treat people with non-small cell lung cancer that has the KRAS G12C mutation. This mutation occurs less frequently in other cancers and is only seen in about 1%–2% of pancreatic cancers. Even so, researchers have begun testing both drugs in small clinical trials of people with other cancers with KRAS G12C mutations. In a trial involving 38 patients with advanced pancreatic cancer, for example, sotorasib shrank tumors in about 20% of participants. Similar results were seen with adagrasib in a trial involving people with advanced colorectal cancer.v

miércoles, 27 de diciembre de 2023

Long COVID: New Info on Who Is Most Likely to Get It Solarina Ho

Chronic Lymphocytic Leukemia Highlights From ASH 2023 John Allan, MD

The 2024 Adult Vaccine Schedule Changes Are Here Sandra Adamson Fryhofer, MD

Starting a Family in Med School Problematic, Say Students Carolyn Crist

FDA approves topical treatment for junctional, dystrophic epidermolysis bullosa Doug Brunk

EU Seeks to Reduce the Risks for Artificial Intelligence Ute Eppinger

Death Risk Takes Decades to Revert to Normal in Ex-Smokers Jürgen Sartorius

Predicting Immune-related Adverse Events from Checkpoint Inhibitors in Melanoma Helen Leask

Noninvasive Ultrasound Benefits Calcified Aortic Valves Anne-Gaëlle Moulun

Device-Detected Atrial High-Rate Episodes Tied to Mortality Marilynn Larkin

Understanding the genetic basis of hereditary diffuse gastric cancer

New model links RNA editing glitch to early-stage type 1 diabetes

Brain bleeds in older adults linked to amyloid deposits in blood vessels

New drug screening system helps uncover promising target for pancreatic cancer treatments

‘Grief has no expiration date': Evidence shows youth gunshots increase mental health & drug disorders By Ted Oberg, News4 Investigative Reporter, Rick Yarborough, Steve Jones and Jeff Piper

Dear new parent: Daycare won’t screw up your baby. Allow the experts to explain why No, your kid will not think you abandoned them.

Addiction treatment for kids and teenagers lags far behind demand

Survey: Teen parents with support report greater well-being

CN-NIAID Symposium seeks ways to promote child health amid challenges

Using a multisystem approach to improve access to autism care in Washington, D.C.

martes, 26 de diciembre de 2023


TOPS Fusion Alternative By Ivanhoe Broadcast News on December 25, 2023


Gene Therapy: Redefining Hemophilia Treatment By Ivanhoe Broadcast News on December 26, 2023


The HAMR Fights Cancer By Ivanhoe Broadcast News on December 27, 2023


AccuCinch Heals Hearts By Ivanhoe Broadcast News on December 28, 2023


Toxic Vacations: Poisoned by Carbon Monoxide By Ivanhoe Broadcast News on December 29, 2023


The Morning After: Hangover Cures That Work By Ivanhoe Broadcast News on December 31, 2023


Fresh Start: Eating Your Way to Better Health In 2024 By Ivanhoe Broadcast News on December 30, 2023


Office Time-Sucks: How to Overcome Productivity Pitfalls By Ivanhoe Broadcast News on December 30, 2023

TRAUMA CENTER FOR SURVIVORS, RESPONDERS OF OCT. 7 MASSACRE Two Israeli organizations partner in Ra’anan Safe Space, a place in nature fostering resilience and healing.

THE HEARING AID HIDDEN IN YOUR GLASSES Nuance Hearing working with global eyewear giant to make efficient and economic hearing aids that fit invisibly into your glasses.

Citrus supplement may ease knee swelling and pain after surgery

MIT engineers develop 'vibing belly' pill to control appetite and curb obesity

Common stomach bacteria may be linked to higher risk of Alzheimer's disease

Shedding new light on the evolution of tuberculosis

Study: Cuddling during sleep comes at a cost, even for mice

Biomarker Research: Neoantigen-targeted TCR-engineered T cell immunotherapy: current advances and challenges

The brain-liver cholinergic anti-inflammatory pathway and viral infections

Univariate and multivariate sex differences and similarities in gray matter volume within essential language-processing areas

Sex differences in the human brain: a roadmap for more careful analysis and interpretation of a biological reality

Behavioral and Brain Functions: Specific brain imaging alterations underlying autistic traits in children with attention-deficit/hyperactivity disorder

Alzheimer's Research & Therapy: Statins and cognitive decline in patients with Alzheimer’s and mixed dementia: a longitudinal registry-based cohort study

Orphanet Journal of Rare Diseases: Experience of life quality from patients with aplastic anemia: a descriptive qualitative study The official journal of Orphanet, the portal for rare diseases and orphan drugs.

LSU Health discovery may open new therapeutic avenues for degenerative diseases of the brain and eye NEI Research News

domingo, 24 de diciembre de 2023

Impact of an antibiotic stewardship initiative on urgent-care respiratory prescribing across patient race, ethnicity, and language

Family Health History

Putting everything in its place: using the INSDC compliant Pathogen Data Object Model to better structure genomic data submitted for public health applications

LETHE: A Digital Intervention for Cognitive Decline. Vasileios S Loukas et al. Annu Int Conf IEEE Eng Med Biol Soc 2023 20231-4

The clinical and epidemiological impacts of whole genomic sequencing on bacterial and virological agents. Sarah Timsit et al. Infect Dis Now 2023 12 104844

HER2/ERBB2 copy number analysis by targeted next-generation sequencing in breast cancer. Daniel Xia et al. Am J Clin Pathol 2023

The infant gut virome is associated with preschool asthma risk independently of bacteria CL Rodriguez et al, Nature Medicine, December 15, 2023 From the abstract: "Here, we analyze the gut virome of 647 children aged 1?year from the Copenhagen Prospective Studies on Asthma in Childhood2010 (COPSAC2010) mother–child cohort, all deeply phenotyped from birth and with longitudinally assessed asthma diagnoses. Specific temperate gut phage taxa were found to be associated with later development of asthma. In particular, the joint abundances of 19 caudoviral families were found to significantly contribute to this association. Combining the asthma-associated virome and bacteriome signatures had additive effects on asthma risk."

How Family History Influences Your Drinking DG Smith, NY Times, December 13, 2023 From the article: " Alcohol use disorder — the inability to stop or control one’s drinking despite negative consequences — is a highly heritable condition. Research suggests that having an immediate family member, like a parent or sibling, with the disorder increases an individual’s chances of developing it roughly three- to fourfold. Approximately 50 percent of a person’s risk comes from their genes, but their home and social environments are also important factors."

Direct to Consumer Biomarker Testing for Alzheimer Disease—Are We Ready for the Insurance Consequences? JJ Arias et al, JAMA Neurology, December 18, 2023 From the article: "The promise of DTC testing for AD biomarkers may be lauded by advocates pushing for earlier diagnoses and individuals’ right to know. Early diagnosis of AD through DTC or clinical evaluations could provide benefits, including increased monitoring and preventive care. Additionally, DTC tests could reduce barriers that impede a timely diagnosis (eg, access to dementia specialists). However, DTC tests are not without hazard, particularly given gaps in discriminatory protections for individuals at risk of developing AD with known biomarker status. "

Systematic review and meta-analysis of AI-based conversational agents for promoting mental health and well-being H Li, NPJ Digital Medicine, December 19, 2023 From the abstract: "Conversational artificial intelligence (AI), particularly AI-based conversational agents (CAs), is gaining traction in mental health care. Despite their growing usage, there is a scarcity of comprehensive evaluations of their impact on mental health and well-being. This systematic review and meta-analysis aims to fill this gap by synthesizing evidence on the effectiveness of AI-based CAs in improving mental health and factors influencing their effectiveness and user experience. "

Using genomics to track malaria in the US T Locke, MedicalXpress, December 20, 2023 From the website: "Both the parasite genome and the mosquito genome are very important because each of those represents a unique fingerprint. You can characterize the disease that's caused by that particular parasite and also track the parasites and the mosquitoes. Malaria parasites, for example, in parts of Ethiopia or India are different from each other, but those malaria parasites in India are similar to each other. If you don't know the origin of a malaria parasite, you can track it back to where it might have come from by comparing it with lots of different genomes of malaria parasites throughout the endemic world. "

sábado, 23 de diciembre de 2023

Publications about Seasonal Affective Disorder (SAD)

Age disparities in glucose-lowering treatment for Danish people with type 2 diabetes: a cross-sectional study between 2019 and 2020 Johansson et al.

The Lancet Gastroenterology & Hepatology in conversation with Sarah Moen on metachronous colorectal cancer risk according to Lynch syndrome pathogenic variant after colectomy

Implementation of a liver health check in people with type 2 diabetes

Primary antibiotic resistance of Helicobacter pylori in the Asia-Pacific region between 1990 and 2022: an updated systematic review and meta-analysis

Upfront necrosectomy for infected necrotising pancreatitis: a promising strategy? Deepak Gunjan,Soumya Jagannath Mahapatra,Pramod Kumar Garg

Effect of an artificial intelligence-assisted system on endoscopic diagnosis of superficial oesophageal squamous cell carcinoma and precancerous lesions: a multicentre, tandem, double-blind, randomised controlled trial

Genetic Signature May Help Tailor Treatment for Meningioma

Red Clover

Following Abnormal Cancer Screening Results, Multi-Level Reminders May Increase Follow-Up

Microplastics as pathogen carriers in water pose environmental and public health risks

Study: Traditional CBT as effective as exposure therapy for fibromyalgia

3D-printed bone: Biomimetic scaffolds offer hope for cranial defect repair

Microglia found to play a key role in regulating the body's response to anesthesia

Sales of emergency contraception estimated to rise after the New Year holiday

viernes, 22 de diciembre de 2023

New NIH MedlinePlus Magazine Now Available

Taking on the stigma of ADHD 'The Amazing Race' winner Penn Holderness explains how his mind works in unique ways

Ask an Expert: Marishka K. Brown, Ph.D., Director of the National Center on Sleep Disorders Research

2023 NIH Research Highlights - Basic Research Insights

2023 NIH Research Highlights - Promising Medical Findings

2023 NIH Research Highlights - Human Health Advances

Sleep loss linked to reduced positivity and heightened anxiety

Groundbreaking treatment tool being developed for male breast cancer diagnosis

Study highlights underutilization of end-of-life care for patients with malignant urinary obstruction

Sniffing women’s tears could be the key to taming male aggression

Study reveals how measles virus mutates and spreads in the human brain

Previously unrecognized class of antibodies can broadly neutralize multiple virus strains

Microplastics as pathogen carriers in water pose environmental and public health risks

Study: Traditional CBT as effective as exposure therapy for fibromyalgia

University of Michigan project seeks to improve control of robotic prosthetic legs

Orphanet Journal of Rare Diseases: Experience of life quality from patients with aplastic anemia: a descriptive qualitative studyv

jueves, 21 de diciembre de 2023

What Is Frontotemporal Dementia?

An implantable device could pave the way for continuous, injection-free diabetes treatment

Statement: Antibody Reduces Allergic Reactions to Multiple Foods in NIH Trial

Antibody reduces allergic reactions to multiple foods in NIH trial

The Ups and Downs of Bipolar Disorder

Fatigue | Mind-Body | Precision Medicine Trials, 12/18/2023

Phone-based Dementia Caregiver Education Program for Latino Families Start: May 1, 2022 End: Jan. 31, 2025 Enrollment: 100

Mobile Health Application To Reduce Caregiver Burden in Hispanic Dementia Caregivers Start: Sept. 26, 2023 End: September 2025 Enrollment: 40

Emergency Preparedness Program for Dementia Caregivers Start: July 12, 2023 End: June 30, 2027 Enrollment: 200

KarXT for Psychosis in People With Alzheimer's Disease Start: December 2023 End: July 2025 Enrollment: 400

Interleukin-2 To Reduce Inflammation in Older Adults With Alzheimer's Disease Start: Mar. 17, 2022 End: Dec. 30, 2025 Enrollment: 40

[11C]-CS1P1 PET Imaging To Detect Brain Inflammation in People With Dementia Start: May 5, 2023 End: May 2026 Enrollment: 80

Virtual Reality for Brain Health Start: Aug. 8, 2023 End: Feb. 1, 2029 Enrollment: 150v

Mindful Walking Program To Slow Cognitive Decline in Older African Americans Start: May 16, 2023 End: Sept. 30, 2025 Enrollment: 114

Find Clinical Trials: Volunteers needed for studies to advance dementia research

6 months of Kaftrio treatment found to reduce inflammation in CF

NIA’s evolving toolbox to study the science of stress

Seeking Success in Science Through NIH-Funded Training BY KIMBERLY ROUSSEAU

Claira Sohn Cultivates Neurons and Diversity in the STEM Community BY ABBEY BIGLER-COYNE

Biomedical STI prevention evidence is inadequate for cisgender women NIH leadership calls for population-specific considerations in study design.

miércoles, 20 de diciembre de 2023

Last Days of Life (PDQ®)–Health Professional Version

RUNX1-Familial Platelet Disorder (PDQ®)–Health Professional Version

DDX41-Associated Myeloid Malignancies (PDQ®)–Health Professional Version

CEBPA-Associated Familial Acute Myeloid Leukemia (PDQ®)–Health Professional Version

Pediatric Gastric Cancer Treatment (PDQ®)–Health Professional Version

Pediatric Chimeric Antigen Receptor (CAR) T-Cell Therapy (PDQ®)–Health Professional Version

Pediatric Allogeneic Hematopoietic Stem Cell Transplant (PDQ®)–Health Professional Version

Osteosarcoma and Undifferentiated Pleomorphic Sarcoma of Bone Treatment (PDQ®)–Health Professional Version

Complications, Graft-Versus-Host Disease, and Late Effects After Pediatric Hematopoietic Stem Cell Transplant (PDQ®)–Health Professional Version

Childhood Thyroid Cancer Treatment (PDQ®)–Health Professional Version

Childhood Rhabdomyosarcoma Treatment (PDQ®)–Health Professional Version

Childhood Pleuropulmonary Blastoma Treatment (PDQ®)–Health Professional Version

Childhood Nasopharyngeal Cancer Treatment (PDQ®)–Health Professional Version

Childhood Melanoma Treatment (PDQ®)–Health Professional Version

Childhood Liver Cancer Treatment (PDQ®)–Health Professional Version

Childhood Laryngeal Tumors Treatment (PDQ®)–Health Professional Version

Childhood Chordoma Treatment (PDQ®)–Health Professional Version

Childhood Basal Cell Carcinoma and Squamous Cell Carcinoma of the Skin Treatment (PDQ®)–Health Professional Version

Chronic sleep deficiency increases insulin resistance in women, especially postmenopausal women

Making Strides to Address COPD in Rural Communities

Stretchable electronics to map the inside of the heart? It’s not from a movie

Eradicating Rheumatic Heart Disease

Mini hearts in a dish: A big win for cardiac research

NIST Calls for Information to Support Safe, Secure and Trustworthy Development and Use of Artificial Intelligence

martes, 19 de diciembre de 2023

Know Your Treatment Options for COVID-19

Skin Cancer Prevention (PDQ®)–Health Professional Version

Chronic Lymphocytic Leukemia Treatment (PDQ®)–Health Professional Version

Cancer of Unknown Primary (CUP) Treatment (PDQ®)–Health Professional Version

Base-Covered HIV-1 Envelope Ectodomains and Their Use

Magnetic Seizure Therapy as Effective as Electroconvulsive Therapy for Treating Depression

Presenters Have Hope for the Future of Trial Design in Pediatric Chronic Kidney Disease

“Mask up!” Soon, AI may be prompting healthcare workers

M.D. in your pocket: New platform allows rare disease patients to carry medical advice everywhere

Modified aquapheresis for the smallest patients in intensive care

Ensuring age-friendly environments for all The Lancet Healthy Longevity

Moderate and vigorous leisure time physical activity in older adults and Alzheimer's disease-related mortality in the USA: a dose–response, population-based study

Personality traits are related to measures of neurodegeneration

Could fasting reset the body’s clock and protect the brain against Alzheimer’s?

FDA updates prescribing information for all opioid pain medicines to provide additional guidance for safe use Includes updates to help reduce unnecessary prescribing

NIH researchers create genetic atlas detailing early stages of zebrafish development Zebrafish are a powerful model for studying embryonic progression in vertebrates.

FDA Approves FRUZAQLA (Fruquintinib) in Refractory Metastatic Colorectal Cancer

Newborn Screening for Severe Combined Immunodeficiency: Lessons Learned from Screening and Follow-Up of the Preterm Newborn Population

W. Kimryn Rathmell begins work as 17th director of the National Cancer Institute

What is the Arkansas Research Alliance?

Beware of Illegally Marketed Diabetes Treatments, Fraudulent Pharmacies

lunes, 18 de diciembre de 2023

Metabolic syndrome linked to higher pancreatic cancer risk, study shows

Study supports limiting red meat intake for type 2 diabetes prevention, highlights alternative protein sources

Late-night eating linked to higher cardiovascular disease risk, study suggests

Air pollution linked to increased risk of stroke and dementia transition, study reveals

Study highlights link between sleep disturbances and behavioral issues in preschool children

Trends in migraine incidence among women of childbearing age from 1990 to 2019 and the prediction for 2030: an analysis of national data in China The Journal of Headache and Pain

Progesterone distribution in the trigeminal system and its role to modulate sensory neurotransmission: influence of sex The Journal of Headache and Pain

Orphanet Journal of Rare Diseases: Real life data: follow-up assessment on Spanish Gaucher disease patients treated with eliglustat. TRAZELGA project

Mental Health Matters Podcast: The Evolution of Brain Stimulation Therapy

REVOLUTIONARY EYELID PACEMAKER ENABLES BLINKING Hundreds of thousands of people suffer from facial paralysis each year, and until now there was no solution for the inability to blink.

REVOLUTIONARY EYELID PACEMAKER ENABLES BLINKING Hundreds of thousands of people suffer from facial paralysis each year, and until now there was no solution for the inability to blink.

Podcast: Rare on Air

A comprehensive approach to mental health

EURORDIS welcomes European Parliament vote on European Health Data Space

The European Conference on Rare Diseases and Orphan Products (ECRD)

Nanoplastics may help set the stage for Parkinson’s risk

Impact of COVID-19 infections and vaccines on preterm birth

Deaths associated with pollution from coal power plants

NIH study shows how genes in retina get regulated during development Genome topology map of human retina development lays foundation for understanding diverse clinical phenotypes in simple and complex eye diseases.

Replication-Competent Virus Detected in Blood of a Fatal COVID-19 Case

Advanced imaging reveals altered brain chemistry of babies with congenital heart disease

Declaring a child brain dead can prompt showdowns. New rules seek to resolve those doubts.

2023 Head and Heart Honoree – Dr. Roger Packer

Novel camera + machine learning = hope for more precise neurosurgery

A new way to treat pediatric gliomas with BRAF V600 mutations

20 years of leadership in the concussion space

domingo, 17 de diciembre de 2023

The infant gut virome is associated with preschool asthma risk independently of bacteria

Beyond the exome: utility of long-read whole genome sequencing in exome-negative autosomal recessive diseases

Attitudes toward pre-symptomatic screening for Alzheimer’s dementia in five European countries: a comparison of family members of people with Alzheimer’s dementia versus non-family members

Post-viral sequelae of COVID-19 and influenza Monica Gandhi

Identifying actionable druggable targets for breast cancer: Mendelian randomization and population-based analyses

Securing the future of Europe's ageing population by 2050 The Lancet Regional Health – Europe

Oral VV116 versus placebo in patients with mild-to-moderate COVID-19 in China: a multicentre, double-blind, phase 3, randomised controlled study

3-year outcomes of discharged survivors of COVID-19 following the SARS-CoV-2 omicron (B.1.1.529) wave in 2022 in China: a longitudinal cohort study

ACE2-independent SARS-CoV-2 virus entry through cell surface GRP78 on monocytes – evidence from a translational clinical and experimental approach

Impact of the COVID-19 pandemic on implementation of novel guideline-directed medical therapies for heart failure in Germany: a nationwide retrospective analysis

sábado, 16 de diciembre de 2023

Therapeutic advances and open questions in postpartum-depression research eBioMedicine

Cellular mechanisms associated with sub-optimal immune responses to SARS-CoV-2 bivalent booster vaccination in patients with Multiple Myeloma

Efficacy and safety of MP1032 plus standard-of-care compared to standard-of-care in hospitalised patients with COVID-19: a multicentre, randomised double-blind, placebo-controlled phase 2a trial

A synbiotic preparation (SIM01) for post-acute COVID-19 syndrome in Hong Kong (RECOVERY): a randomised, double-blind, placebo-controlled trial

Story of discovery: NEI-funded research paves way for new dry AMD drugs FDA approves first drugs to treat the dry form of age-related macular degenerationStory of discovery: NEI-funded research paves way for new dry AMD drugs FDA approves first drugs to treat the dry form of age-related macular degeneration


Damn Dinks! Playing Pickleball Pain-Free By Ivanhoe Broadcast News on December 24, 2023


AI Fraud Alert: Don’t Fall for Deepfakes By Ivanhoe Broadcast News on December 23, 2023


Pass on The Joy: Gifts that Give By Ivanhoe Broadcast News on December 23, 2023


Beating Late-Stage Cancers By Ivanhoe Broadcast News on December 22, 2023


Ketamine Works on Treatment-Resistant Depression By Ivanhoe Broadcast News on December 21, 2023


Fibroids Freedom: A Hysterectomy-Free Solution By Ivanhoe Broadcast News on December 20, 2023


Pill-less Pain Relief: Neurostimulators Replacing Opioids By Ivanhoe Broadcast News on December 19, 2023


Rolling Away Blood Clots By Ivanhoe Broadcast News on December 18, 2023

FDA approves enfortumab vedotin-ejfv with pembrolizumab for locally advanced or metastatic urothelial cancer

The Lancet Regional Health in conversation with Sibylle Pramhas and Kristian Petersen on cannabidiol for painful knee osteoarthritis

African American patients face lifetime of challenges living with CF Interviews detail cultural insensitivity from healthcare teams, other concerns

Urinary Fas a potential biomarker for antibiotic-linked kidney injury Researchers analyzed urine samples before and after antibiotic treatment

Medical trauma bubbles to the surface again after a hospitalization With medical PTSD, it's challenging to return to a hospital setting

Experiencing the Neural Symphony Underlying Memory through a Blend of Science and Art Posted on December 8th, 2023 by John Ngai, PhD, NIH BRAIN Initiative

Effect of baseline oestradiol serum concentration on the efficacy of anastrozole for preventing breast cancer in postmenopausal women at high risk: a case-control study of the IBIS-II prevention trial

jueves, 14 de diciembre de 2023

Human Gene Therapy

Summary of Advances In Autism Research 2022

Taking on the stigma of ADHD

Antibody Drug Ejects Problematic Proteins from Cancer Cells

NIH research identifies opportunities to improve future HIV vaccine candidates Study suggests greater CD8+ T-cell activity may increase HIV immunity

Reported drug use among adolescents continued to hold below pre-pandemic levels in 2023 New data show relatively low use of illicit substances, yet overdose death rates among teens have risen in recent years.

Brain Initiative Cell Census Network 2.0

The Brain Research Through Advancing Innovative Neurotechnologies® (BRAIN) Initiative

Scientists Unveil Complete Cell Map of a Whole Mammalian Brain NIH-funded atlas characterizes over 32 million cells across the mouse brain

Berberine and Weight Loss: What You Need To Know Berberine is a substance found in a variety of plants, including goldenseal, barberry, Oregon grape, and others. Plants containing berberine have a long history of use in both Ayurvedic and Chinese medicine. In modern times, plants containing berberine have been used for infections, skin diseases, digestive disorders, and other conditions. Berberine is currently being studied for its effects on diabetes and risk factors for heart disease. Recently, it has become popular as a potential weight loss aid.

Children taking CFTR modulators may grow taller by age 18 Use of therapy may help bridge gap in adult height, study suggests

Drop in blood sugar levels seen within months of starting Kaftrio But for CF patients with diabetes, need for insulin goes unchanged

Fighting for global access to equitable CF healthcare, treatment Potentially lifesaving therapies should be available to patients in all countries

Cough, sputum symptoms tied to impaired quality of life: Pilot study Researchers applied CASA-Q to 48 adults with CF

Will variants of uncertain significance still exist in 2030? From the abstract: "In 2020, the National Human Genome Research Institute (NHGRI) made ten “bold predictions,” including that “the clinical relevance of all encountered genomic variants will be readily predictable, rendering the diagnostic designation ‘variant of uncertain significance (VUS)’ obsolete.” We discuss the prospects for this prediction, arguing that many, if not most, VUS in coding regions will be resolved by 2030. We outline a confluence of recent changes making this possible. "

Comprehensive assessment of the genetic characteristics of small for gestational age newborns in NICU: from diagnosis of genetic disorders to prediction of prognosis From the abstract: "Among the 723 SGA newborns, 88(12.2%) received genetic diagnosis, including 42(47.7%) with monogenic diseases and 46(52.3%) with chromosomal abnormalities. SGA with genetic diagnosis showed higher rates in severe SGA(54.5% vs. 41.9%, P=0.0025) than SGA without genetic diagnosis. SGA with chromosomal abnormalities showed higher incidences of physical and neurodevelopmental delay compared to those with monogenic diseases (45.7% vs. 19.0%, P=0.012). "

'It's all gone': CAR-T therapy forces autoimmune diseases into remission From the article: "Engineered immune cells have given 15 people with once-debilitating autoimmune disorders a new lease on life, free from fresh symptoms or treatments. The results raise hopes that the approach — called CAR-T-cell therapy — might one day be extended to a variety of other conditions fuelled by rogue immune cells that produce antibodies against the body’s own tissues. "

Utility of smart watches for identifying arrhythmias in children From the abstract: " Arrhythmia symptoms are frequent complaints in children and often require a pediatric cardiology evaluation. Data regarding the clinical utility of wearable technologies are limited in children. We hypothesize that a smart watch can capture arrhythmias in children. We present an analysis of patients =18 years-of-age who had signs of an arrhythmia documented by a smart watch. We include patients evaluated at our center over a 4-year-period and highlight those receiving a formal arrhythmia diagnosis. We evaluate the role of the smart watch in arrhythmia diagnosis, the results of other ambulatory cardiac monitoring studies, and findings of any EP studies."

Science Snippet: Zooming In on Nanoparticles BY ABBEY BIGLER-COYNE

FDA approves eflornithine for adult and pediatric patients with high-risk neuroblastoma

miércoles, 13 de diciembre de 2023

How to Prescribe Zepbound Beverly Tchang, MD

Relapsed DLBCL: With Complete Interim Response, SCT Outperforms CAR T Nancy A Melville

Women Older Than 50 May Safely Deescalate Mammogram Frequency Following Surgery Jim Kling

Exercise Plan Cost-Effective in Post-Stroke Cognitive Rehab Carolyn Crist

ADA Issues New Screening, Obesity Management Recommendations Miriam E. Tucker



Possible Sickle Cell Solution By Ivanhoe Broadcast News on November 14, 2023


Lifesaving Tech Prevents Sudden Cardiac Arrest By Ivanhoe Broadcast News on November 15, 2023


Wi-Fi Woes: Factors That Cripple Your Connection By Ivanhoe Broadcast News on December 17, 2023


Soul-Soothing Foods to Beat the Winter Blues By Ivanhoe Broadcast News on December 16, 2023


How to “Sleigh” Your Budget & Save Hundreds this Holiday By Ivanhoe Broadcast News on December 16, 2023




Ahead of the Biological Clock: Early Menopause Triggers By Ivanhoe Broadcast News on December 15, 2023


Kwanzaa: 7 Essential Facts to Illuminate the Celebration By Ivanhoe Broadcast News on December 14, 2023


AI Super Charges MRI By Ivanhoe Broadcast News on December 13, 2023


Epilepsy: Tesla Targets By Ivanhoe Broadcast News on December 12, 2023


Esophageal Cancer: A Premier Way to Treat By Ivanhoe Broadcast News on December 11, 2023

Strong association shown between being sedentary and dementia risk

Speaking Up About Mental Health National Essay Contest

Intubation could become a relic of the Covid era Getting its inspiration from nature, a medical-device company is developing a less invasive way to oxygenate blood without mechanical ventilation. It’s a vital step forward.

Israeli startup’s weight-loss pill aces clinical trials A capsule that transforms into a temporary triangular device in the stomach proves to aid weight loss, helping users lose 10 to 30 pounds.

PREVENT PAINFUL BEDSORES BY SPOTTING THEM BEFORE THEY HAPPEN A new infrared technology noninvasively checks under patients’ skin for signs of pressure injuries forming before they break through to the skin.

Gut microbes may aid early gestational diabetes diagnosis Researchers use fecal and serum samples to predict which pregnant women will later develop the condition.

AYURVEDIC HERBAL SUPPLEMENT TARGETS DIABETES Curalin, sold in 14 countries, also has off-label anecdotal indications for stress reduction, improved metabolism and insomnia.

martes, 12 de diciembre de 2023

Improving haematological care for adolescents The Lancet Haematology

Germline predisposition traits in allogeneic hematopoietic stem-cell transplantation for myelodysplastic syndromes: a survey-based study and position paper on behalf of the Chronic Malignancies Working Party of the EBMT

What is the true story of FNAIT-induced complications? Mette Kjær

R-CODOX-M/R-IVAC versus DA-EPOCH-R in patients with newly diagnosed Burkitt lymphoma (HOVON/SAKK): final results of a multicentre, phase 3, open-label, randomised trial

Adding Mindfulness-Oriented Recovery Enhancement (MORE) to Methadone Treatment Provides Therapeutic Benefits for People With Opioid Use Disorder and Chronic Pain

Daily Tailored Text Messages Curb Risky Drinking Eve Bender

Eating Disorder Hospitalizations Increase in Canadian Kids Kate Johnson

Renal Denervation for Hypertension: How Will It Be Used? Sue Hughes

ADA Issues New Screening, Obesity Management Recommendations Miriam E. Tucker

CGRP in Migraine Prodrome Can Stop Headache, Reduce Severity Sue Hughes

Why Are Prion Diseases on the Rise? F. Perry Wilson, MD, MSCE

Specific Personality Traits May Influence Dementia Risk Megan Brooks