lunes, 2 de diciembre de 2024

Scientists confront a mystery: Why have U.S. bird flu cases been so mild? While grateful, many are perplexed by the H5N1 outbreak’s lack of severity

Scientists confront a mystery: Why have U.S. bird flu cases been so mild? While grateful, many are perplexed by the H5N1 outbreak’s lack of severity Since the outbreak of H5N1 bird flu in American dairy cattle began this spring, there have been 55 cases among people in the U.S. That’s an alarming number, but a surprising bright side is that all the infections have been mild so far. Bird flu has a reputation — well-earned, STAT’s Helen Branswell says — as a very dangerous pathogen, with a case fatality rate around 50%. So what’s happening here? Helen spoke to 21 researchers who have studied influenza, and this one in particular, for years. Nobody has definitive answers (“If you find out, please let me know!” one researcher told Helen), but plenty raised theories and questions. Could the way that the virus is being transmitted limit its severity? Do we actually have some protection to it already? With such limited information, the train of thought can even get existential: Has the virus changed? Have we?

Vorasidenib for Certain IDH-Mutant Gliomas: Is It Worth It? Kate Johnson December 02, 2024

https://www.medscape.com/viewarticle/vorasidenib-certain-idh-mutant-gliomas-it-worth-it-2024a1000lvu

ASH 2024: New Leukemia Txs, Fewer Blood Clots With GLP-1 Rxs Randy Dotinga December 02, 2024

https://www.medscape.com/viewarticle/ash-2024-new-leukemia-txs-fewer-blood-clots-glp-1-rxs-2024a1000lwo

Is 1-Week Radiotherapy Safe for Breast Cancer? Edited by Gargi Mukherjee December 02, 2024

https://www.medscape.com/viewarticle/1-week-radiotherapy-safe-breast-cancer-2024a1000lwy

Accelerated Approval of New Frontline TKI Use in CML Raises Questions Kerry Dooley Young December 02, 2024 asciminib (Scemblix, Novartis AG)

https://www.medscape.com/viewarticle/accelerated-approval-new-frontline-tki-use-cml-raises-2024a1000lx4

Ultra-processed foods increase active psoriasis risk, study shows

https://www.news-medical.net/news/20241201/Ultra-processed-foods-increase-active-psoriasis-risk-study-shows.aspx

Fibroblastic reticular cells power immune defenses in lung cancer

https://www.news-medical.net/news/20241201/Fibroblastic-reticular-cells-power-immune-defenses-in-lung-cancer.aspx

Quabodepistat combo shows promise for safer, faster tuberculosis treatment

https://www.news-medical.net/news/20241201/Quabodepistat-combo-shows-promise-for-safer-faster-tuberculosis-treatment.aspx

Neural connectivity predicts deep brain stimulation success in essential tremor

https://www.news-medical.net/news/20241201/Neural-connectivity-predicts-deep-brain-stimulation-success-in-essential-tremor.aspx

Star power eclipses science in obesity discussions on social media

https://www.news-medical.net/news/20241201/Star-power-eclipses-science-in-obesity-discussions-on-social-media.aspx

Heart health benefits soar with regular sleep schedules, research finds

https://www.news-medical.net/news/20241201/Heart-health-benefits-soar-with-regular-sleep-schedules-research-finds.aspx

Gut transit time and pH shape microbiome individuality and dietary responses

https://www.news-medical.net/news/20241201/Gut-transit-time-and-pH-shape-microbiome-individuality-and-dietary-responses.aspx

Visceral fat found to contribute to Alzheimer's disease development

https://www.news-medical.net/news/20241202/Visceral-fat-found-to-contribute-to-Alzheimers-disease-development.aspx

Engineered stone countertop workers at risk for silicosis

https://www.news-medical.net/news/20241202/Engineered-stone-countertop-workers-at-risk-for-silicosis.aspx

New study explores obecabtagene autoleucel for adults with hard-to-treat leukemia

https://www.news-medical.net/news/20241202/New-study-explores-obecabtagene-autoleucel-for-adults-with-hard-to-treat-leukemia.aspx

How Dysregulated Cell Signaling Causes Disease

https://www.news-medical.net/health/How-Dysregulated-Cell-Signaling-Causes-Disease.aspx

Baby's adorable reaction to his new glasses attracts worldwide attention: 'Melts hearts' The video brings 'joy, happiness and positivity,' his mom tells Fox News Digital Ashley Papa By Ashley Papa Fox News Published November 30, 2024 6:00am EST

Baby's adorable reaction to his new glasses attracts worldwide attention: 'Melts hearts' The video brings 'joy, happiness and positivity,' his mom tells Fox News Digital Ashley Papa By Ashley Papa Fox News Published November 30, 2024 6:00am EST https://www.foxnews.com/health/babys-adorable-reaction-glasses-attracts-worldwide-attention-melts-hearts

Medical devices could become safer with this new breakthrough, experts say New blood vessel-like coating could prevent dangerous bleeding and clotting, research suggests Angelica Stabile By Angelica Stabile Fox News Published November 30, 2024 9:00am EST

Medical devices could become safer with this new breakthrough, experts say New blood vessel-like coating could prevent dangerous bleeding and clotting, research suggests Angelica Stabile By Angelica Stabile Fox News Published November 30, 2024 9:00am EST https://www.foxnews.com/health/medical-devices-could-become-safer-new-breakthrough-experts-say

Do women need more sleep than men? Here’s what experts think Sleep doctors reveal the specific challenges women face in getting the rest they need Angelica Stabile By Angelica Stabile Fox News Published December 1, 2024 6:00am EST

Do women need more sleep than men? Here’s what experts think Sleep doctors reveal the specific challenges women face in getting the rest they need Angelica Stabile By Angelica Stabile Fox News Published December 1, 2024 6:00am EST https://www.foxnews.com/health/do-women-need-more-sleep-men-heres-what-experts-think

Alcohol deaths have more than doubled in recent years, especially among women Experts reveal how many drinks are likely to have harmful effects Melissa Rudy By Melissa Rudy Fox News Published December 2, 2024 6:00am EST

Alcohol deaths have more than doubled in recent years, especially among women Experts reveal how many drinks are likely to have harmful effects Melissa Rudy By Melissa Rudy Fox News Published December 2, 2024 6:00am EST https://www.foxnews.com/health/alcohol-deaths-have-more-doubled-recent-years-especially-among-women

domingo, 1 de diciembre de 2024

Laetrile/Amygdalin (PDQ®)–Health Professional Version

https://www.cancer.gov/about-cancer/treatment/cam/hp/laetrile-pdq

Milk Thistle (PDQ®)–Health Professional Version

https://www.cancer.gov/about-cancer/treatment/cam/hp/milk-thistle-pdq

Black Cohosh (PDQ®)–Health Professional Version

https://www.cancer.gov/about-cancer/treatment/cam/hp/black-cohosh-pdq

Aromatherapy With Essential Oils (PDQ®)–Health Professional Version

https://www.cancer.gov/about-cancer/treatment/cam/hp/aromatherapy-pdq

Prostate Cancer, Nutrition, and Dietary Supplements (PDQ®)–Health Professional Version

https://www.cancer.gov/about-cancer/treatment/cam/hp/prostate-supplements-pdq

Mistletoe Extracts (PDQ®)–Health Professional Version

https://www.cancer.gov/about-cancer/treatment/cam/hp/mistletoe-pdq

Medicinal Mushrooms (PDQ®)–Health Professional Version

https://www.cancer.gov/about-cancer/treatment/cam/hp/mushrooms-pdq

Curcumin (Curcuma, Turmeric) and Cancer (PDQ®)–Health Professional Version

https://www.cancer.gov/about-cancer/treatment/cam/hp/curcumin-pdq

Coenzyme Q10 (PDQ®)–Health Professional Version

https://www.cancer.gov/about-cancer/treatment/cam/hp/coenzyme-q10-pdq

Cancer Therapy Interactions With Foods and Dietary Supplements (PDQ®)–Health Professional Version

https://www.cancer.gov/about-cancer/treatment/cam/hp/dietary-interactions-pdq

Complementary and Alternative Medicine

https://www.cancer.gov/about-cancer/treatment/cam

Cannabis and Cannabinoids (PDQ®)–Health Professional Version

https://www.cancer.gov/about-cancer/treatment/cam/hp/cannabis-pdq?cid=eb_govdel#top

Hereditary Leiomyomatosis and Renal Cell Cancer (PDQ®)–Health Professional Version

https://www.cancer.gov/publications/pdq/information-summaries/genetics/hlrcc-syndrome-hp-pdq?cid=eb_govdel#top

Genetics of Skin Cancer (PDQ®)–Health Professional Version

https://www.cancer.gov/types/skin/hp/skin-genetics-pdq?cid=eb_govdel#top

Fatigue (PDQ®)–Health Professional Version

https://www.cancer.gov/about-cancer/treatment/side-effects/fatigue/fatigue-hp-pdq?cid=eb_govdel#top

Cognitive Impairment in Adults With Cancer (PDQ®)–Health Professional Version

https://www.cancer.gov/about-cancer/treatment/side-effects/memory/cognitive-impairment-hp-pdq?cid=eb_govdel#top

Neuroblastoma Treatment (PDQ®)–Health Professional Version

https://www.cancer.gov/types/neuroblastoma/hp/neuroblastoma-treatment-pdq?cid=eb_govdel#top

Childhood Non-Hodgkin Lymphoma Treatment (PDQ®)–Health Professional Version

https://www.cancer.gov/types/lymphoma/hp/child-nhl-treatment-pdq?cid=eb_govdel#top

Up all night to make a new drug for narcolepsy After tackling toxicity and a trial halt, Elena Koundourakis and her team at Takeda are on the cusp of a first-in-class drug for people living with narcolepsy.

https://www.drugdiscoverynews.com/up-all-night-to-make-a-new-drug-for-narcolepsy-16152

Coenzyme Q10

https://www.nccih.nih.gov/health/coenzyme-q10?nav=govd Coenzyme Q10 (CoQ10) is a substance that is naturally present in the human body, with the highest levels in the heart, liver, kidneys, and pancreas. It is sold in the United States as a dietary supplement. Researchers have been investigating its possible health benefits. CoQ10 has not been shown to be of value in treating cancer, but it may reduce the risk of heart damage caused by one type of cancer chemotherapy drug. CoQ10 may reduce the risk of some complications of heart surgery, but studies on whether it might help to prevent heart disease have had inconclusive results. Although results of individual studies have varied, the overall evidence does not support the idea that CoQ10 can reduce muscle pain caused by the cholesterol-lowering drugs known as statins.

sábado, 30 de noviembre de 2024

BEWARE: DOCTORS QUESTION ASPIRIN A DAY

Beware: Doctors Question Aspirin a Day By Ivanhoe Broadcast News on November 24, 2024 https://www.ivanhoe.com/family-health/beware-doctors-question-aspirin-a-day/

A Path to Reduce the Number of Pre-Emptive Mastectomies – In-Depth Doctor’s Interview By Ivanhoe Broadcast News on July 22, 2024

https://www.ivanhoe.com/interview/a-path-to-reduce-the-number-of-pre-emptive-mastectomies-in-depth-doctors-interview/

WEIGHT LOSS AND WELLNESS TRENDS: HYPE OR DOPE?

Weight Loss and Wellness Trends: Hype or Dope? By Ivanhoe Broadcast News on December 8, 2024 https://www.ivanhoe.com/?p=34652&preview=1&_ppp=d5fbeadb5f

CERTAIN CHEMICAL LINKED TO EARLY PUBERTY

Certain Chemical Linked to Early Puberty By Ivanhoe Broadcast News on December 7, 2024 https://www.ivanhoe.com/?p=34649&preview=1&_ppp=7d2c38ec13

SALVAGE HIFU: SAVING THE PROSTATE AFTER RECURRENCE

Salvage HIFU: Saving the Prostate After Recurrence By Ivanhoe Broadcast News on December 7, 2024 https://www.ivanhoe.com/?p=34646&preview=1&_ppp=faaaf042bd

STROKE STRIKES EARLIER: A GROWING CONCERN

Stroke Strikes Earlier: A Growing Concern By Ivanhoe Broadcast News on December 6, 2024 https://www.ivanhoe.com/?p=34643&preview=1&_ppp=68e0129ce6

SUPPLEMENTS: GOOD OR BAD FOR YOUR HEALTH?

Supplements: Good or Bad for Your Health? By Ivanhoe Broadcast News on December 5, 2024 https://www.ivanhoe.com/?p=34640&preview=1&_ppp=e7e9410714

SCIENCE LAB FOR SICK KIDS

Science Lab for Sick Kids By Ivanhoe Broadcast News on December 4, 2024 https://www.ivanhoe.com/?p=34636&preview=1&_ppp=a8c05111b8

VISION ISSUES AND DEMENTIA: A STRONG CONNECTION

Vision Issues and Dementia: A Strong Connection By Ivanhoe Broadcast News on December 3, 2024 https://www.ivanhoe.com/?p=34633&preview=1&_ppp=2962a368dc

DANGEROUS FOOD ALLERGY REACTIONS: A DRUG-FREE LIFE?

Dangerous Food Allergy Reactions: A Drug-Free Life? By Ivanhoe Broadcast News on December 2, 2024 https://www.ivanhoe.com/?p=34629&preview=1&_ppp=34ffcdcc2f

KIT’s 3ROCKIT 3R Center works towards developing methods to replace animal testing

https://www.news-medical.net/news/20241129/KITe28099s-3ROCKIT-3R-Center-works-towards-developing-methods-to-replace-animal-testing.aspx

Study highlights the health risk of PM2.5 exposure for pregnant women

https://www.news-medical.net/news/20241129/Study-highlights-the-health-risk-of-PM25-exposure-for-pregnant-women.aspx

The Evolution of HIV Diagnostic Testing

https://www.news-medical.net/health/The-Evolution-of-HIV-Diagnostic-Testing.aspx

Global Perspectives on the Latest Antibody-Drug Conjugate Advances in Breast Cancer: A Year in Review Authors: Fabrice André, MD, PhD; Nadia Harbeck, MD, PhD; Aditya Bardia, MD, MPH

https://www.medscape.org/viewarticle/1000738?sso=true&uac=148436CN&src=mkmcmr_driv_cust_mscpedu_241129-OUS-HONC-1000738-cta

Treating eosinophilic exacerbations of asthma and COPD with benralizumab (ABRA): a double-blind, double-dummy, active placebo-controlled randomised trial

https://www.thelancet.com/journals/lanres/article/PIIS2213-2600(24)00299-6/fulltext?dgcid=hubspot_email_conferencealerts_bts24&utm_campaign=conferencealerts&utm_medium=email&_hsenc=p2ANqtz--taaFVYiEwiWjRi3XYAvSSBgC1qeSQw_JUAY3QeOFoP-jLTCMEnNvxNKM4ff6h61dHvyNzjV2VQSSOeLQJMA85emeY4Q&_hsmi=335902023&utm_content=335902023&utm_source=hs_email

Respiratory symptoms and lung function trajectories: does wheeze hold the answer?

https://www.thelancet.com/journals/lanres/article/PIIS2213-2600(24)00337-0/abstract?utm_campaign=conferencealerts&utm_medium=email&dgcid=hubspot_email_conferencealerts_bts24&_hsenc=p2ANqtz-8Pg_Otcokz_vSQmu7ZNGalg5v7gxZ3NFzCkLFL34EVZRrGR9EXSRnqQAHmi3ROTajipiVQ1yFAs62VrwxX5oxxfaR8hg&_hsmi=335902023&utm_content=335902023&utm_source=hs_email

Stratifying Risk: Reducing Recurrence in Early Breast Cancer

https://www.medscape.com/mtv/breast-cancer-ous-s02/e01?src=vid_pil

Clinical Trials Update from NCI, November 2024

https://content.govdelivery.com/accounts/USNIHNCI/bulletins/3c220de?reqfrom=share

Does Screening at 40-49 Years Boost Breast Cancer Survival? Louise Gagnon November 28, 2024

https://www.medscape.com/viewarticle/does-screening-40-49-years-boost-breast-cancer-survival-2024a1000lri?ecd=wnl_edit_tpal_etid7042666&uac=148436CN&impID=7042666

Modeling Health and Economic Outcomes of Eliminating Sex Disparities in Youth Physical Activity

https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2827024?resultClick=3&utm_campaign=hdpulse&utm_medium=email&utm_source=govdelivery An NIMHD-led study published in JAMA Network Open examined the effects of sex disparities in physical activity and sports participation among U.S. youth. The study found that reducing these disparities could prevent 30,000 cases of obesity and other health conditions, saving up to $780 million in lifetime health care costs. This research highlights actionable strategies to support equity in physical activity, such as: Hiring more female coaches. Showcasing women athletes as role models. Implementing mentoring programs. Investing in under-resourced schools and communities to create safe and supportive environments for girls to stay active. The study was led by Dr. Kosuke Tamura, NIH’s Stadtman Investigator and NIH Distinguished Scholar, who directs the Socio-Spatial Determinants of Health Laboratory in NIMHD’s Division of Intramural Research.

viernes, 29 de noviembre de 2024

Behavioral and Brain Functions

https://behavioralandbrainfunctions.biomedcentral.com/

A therapeutic approach to pantothenate kinase associated neurodegeneration: a pilot study

https://ojrd.biomedcentral.com/

Digital health technologies play a transformative role in diabetes management and prevention

https://www.news-medical.net/news/20241112/Digital-health-technologies-play-a-transformative-role-in-diabetes-management-and-prevention.aspx?utm_source=news_medical_newsletter&utm_medium=email&utm_campaign=medtech_newsletter_25_november_2024

The Future is Wearable: Advancing Human Health Through Portable Spectroscopy

https://www.news-medical.net/news/20240718/The-Future-is-Wearable-Advancing-Human-Health-Through-Portable-Spectroscopy.aspx?utm_source=news_medical_newsletter&utm_medium=email&utm_campaign=medtech_newsletter_25_november_2024

Study reveals varied risks of hormone treatments for menopausal symptoms

https://www.news-medical.net/news/20241128/Study-reveals-varied-risks-of-hormone-treatments-for-menopausal-symptoms.aspx

How genetic traits contribute to earlier diabetes onset and metabolic challenges in South Asians

https://www.news-medical.net/news/20241128/How-genetic-traits-contribute-to-earlier-diabetes-onset-and-metabolic-challenges-in-South-Asians.aspx

New model can explain neural and behavioral differences in autism spectrum disorder

https://www.news-medical.net/news/20241128/New-model-can-explain-neural-and-behavioral-differences-in-autism-spectrum-disorder.aspx

STAG2 loss linked to increased aggression in Ewing sarcoma

https://www.news-medical.net/news/20241129/STAG2-loss-linked-to-increased-aggression-in-Ewing-sarcoma.aspx

Empowering Asthma Care: Bedfont® Scientific Limited Provides Vital Support for FeNO Testing in Response to Updated NICE Asthma Guidelines

https://www.news-medical.net/news/20241129/Empowering-Asthma-Care-Bedfontc2ae-Scientific-Limited-Provides-Vital-Support-for-FeNO-Testing-in-Response-to-Updated-NICE-Asthma-Guidelines.aspx

Black athletes face higher risk of sudden cardiac arrest and death

https://www.news-medical.net/news/20241128/Black-athletes-face-higher-risk-of-sudden-cardiac-arrest-and-death.aspx

Better maternal diet boosts brain growth and IQ in kids

https://www.news-medical.net/news/20241127/Better-maternal-diet-boosts-brain-growth-and-IQ-in-kids.aspx

Sleep regularity and major adverse cardiovascular events: a device-based prospective study in 72 269 UK adults

https://jech.bmj.com/content/early/2024/10/30/jech-2024-222795?utm_campaign=morning_rounds&utm_medium=email&_hsenc=p2ANqtz-8p7ASuvTO2uIksORF5DzMiJctKO_Ol8tFHYmWde2YymUrhdkcCkO_411oyEzavw6NBWega57fd5pryR8mEjZVfUk_woA&_hsmi=335871632&utm_content=335871632&utm_source=hs_email Study says: Irregular sleep linked to risk of heart failure, stroke Irregular sleep patterns are linked with a significantly higher risk of major cardiovascular health events like heart failure, stroke, and myocardial infarction, according to a study published yesterday in the Journal of Epidemiology and Community Health. People with moderately irregular sleep schedules can see their risk offset if they still meet the recommended number of hours for sleep for their age group, the study found. But that wasn’t true for the most irregular sleepers. Researchers analyzed eight years of data from more than 72,000 people ages 40 to 79 who, as part of the UK Biobank project, wore tracking devices on their wrist for one week. None of the participants had a history of severe heart problems. Regular vs. irregular patterns were assessed using something called the Sleep Regularity Index — a calculation of the probability that someone is awake or asleep at any two times 24 hours apart. Another study from January also found that sleep regularity was a stronger prediction of mortality risk than sleep duration. Authors of both studies argue that sleep regularity might be even more important to one’s health than sleep duration. Validation of the Sleep Regularity Index in Older Adults and Associations with Cardiometabolic Risk https://www.nature.com/articles/s41598-018-32402-5?utm_campaign=morning_rounds&utm_medium=email&_hsenc=p2ANqtz--Qb-FzbrHEkD7UHTwNXcsfGyILTV-XQ9U3fpH-F3Jc0xXQ-ZtTClbpKGR6SrcDHnrCxzjhVPQ4CwJiXh82MAe-wvu1_w&_hsmi=335871632&utm_content=335871632&utm_source=hs_email Sleep regularity is a stronger predictor of mortality risk than sleep duration: A prospective cohort study https://academic.oup.com/sleep/article/47/1/zsad253/7280269?utm_campaign=morning_rounds&utm_medium=email&_hsenc=p2ANqtz-99X2KkyM9iPyGu7LcSOVA3LAt6rfc5StWU7uYPOtp3-Ef9iOBSVQdqoa4-tQLeLzZTZ4J3kOJyz2JD3bC8thKVMe4r0A&_hsmi=335871632&utm_content=335871632&utm_source=hs_email

Issue Brief: Co-Occurring Mental Health and Substance Use

https://store.samhsa.gov/product/issue-brief-co-occurring-mental-health-and-substance-use/pep24-01-008?utm_source=SAMHSA&utm_campaign=9da12f019d-EMAIL_CAMPAIGN_2024_11_26_09_31&utm_medium=email&utm_term=0_-9da12f019d-167840245

Newer epilepsy medications used during pregnancy do not affect neurological development in children NIH-funded study provides clarity on safety of two common antiseizure drugs lamotrigine and levetiracetam.

https://www.nih.gov/news-events/news-releases/newer-epilepsy-medications-used-during-pregnancy-do-not-affect-neurological-development-children

Navigating Diagnosis and Treatment for Primary Biliary Cholangitis: The Integral Role of the Patient Voice // Thyroid Eye Disease: Overview, Diagnosis, and Current and Emerging Treatment Options

Navigating Diagnosis and Treatment for Primary Biliary Cholangitis: The Integral Role of the Patient Voice https://checkrare.com/navigating-diagnosis-and-treatment-for-primary-biliary-cholangitis/ Navigating Diagnosis and Treatment for Primary Biliary Cholangitis: The Integral Role of the Patient Voice Dr. Sonal Kumar, an Assistant Professor of Medicine, and Director of Clinical Hepatology at Weill Cornell Medical College in New York, NY discusses the integral role of the patient voice in navigating treatment decisions and determining an individualized care plan for people living with primary biliary cholangitis (PBC) that reflects their needs and goals. Thyroid Eye Disease: Overview, Diagnosis, and Current and Emerging Treatment Options Thyroid Eye Disease: Overview, Diagnosis, and Current and Emerging Treatment Options Raymond Douglas, MD, PhD, a world-leading clinician and thought leader in thyroid eye disease (TED) who has been integral to developing therapeutics for the disease, provides an overview of TED, including diagnosis challenges and current and emerging treatments for this rare disease. https://checkrare.com/thyroid-eye-disease-overview-and-diagnosis/

Oral Drug Effective for Rare WHIM Syndrome, Approved by FDA

https://ashpublications.org/ashclinicalnews/news/7930/oral-drug-effective-for-rare-whim-syndrome Oral Drug Effective for Rare WHIM Syndrome, Approved by FDA Treatment with mavorixafor reduced infection frequency, severity and duration of infections, and antibiotic use among individuals with warts, hypogammaglobulinemia, infections, and myelokathexis (WHIM) syndrome in a phase III ­placebo-controlled clinical trial.

The diabetes gene that broke all the rules Researchers discovered a new gene required for pancreas development, but much to their surprise, they found that it was absent in all animals except primates.

https://www.drugdiscoverynews.com/the-diabetes-gene-that-broke-all-the-rules-15880?utm_campaign=DDN_Newsletter_Dose&utm_medium=email&_hsenc=p2ANqtz-_lYXAcjAeY0WuFlE7HB0WXHHVW23Dx1i3Nrw3UePHj87-2R-qomI_qUU5h5BJIeQlvRZmkWFKTUvXT9F_u5n0A2SVanw&_hsmi=335975913&utm_content=335975913&utm_source=hs_email

Posted onNovember 27, 2024 What Are Stem Cells? by Kimberly Smith

https://biobeat.nigms.nih.gov/2024/11/what-are-stem-cells/?utm_medium=email&utm_source=govdelivery

Meet the Director: Bruce J. Tromberg, Ph.D., National Institute of Biomedical Imaging and Bioengineering

https://magazine.medlineplus.gov/

Do you know your family health history? It can help reduce your health risks, but asking relatives can be awkward. These tips can help.

https://magazine.medlineplus.gov/article/8-health-questions-to-ask-your-family-members?utm_medium=email&utm_source=govdelivery

jueves, 28 de noviembre de 2024

Younger age at type 2 diabetes diagnosis increases mortality risk

https://www.news-medical.net/news/20241127/Younger-age-at-type-2-diabetes-diagnosis-increases-mortality-risk.aspx

Culturally appropriate interventions strengthen healthcare responses to domestic violence

https://www.news-medical.net/news/20241127/Culturally-appropriate-interventions-strengthen-healthcare-responses-to-domestic-violence.aspx

Study reveals protein mobility defect as a key factor in chronic diseases

https://www.news-medical.net/news/20241127/Study-reveals-protein-mobility-defect-as-a-key-factor-in-chronic-diseases-Chronic-Diseases.aspx

Novel mRNA-based therapy offers hope for patients with proliferative vitreoretinopathy

https://www.news-medical.net/news/20241127/Novel-mRNA-based-therapy-offers-hope-for-patients-with-proliferative-vitreoretinopathy-Mass-Eye-And-Ear-Le.aspx

Understanding the pathophysiological relationship between OSA and metabolic syndrome - obstructive sleep apnea (OSA) // metabolic syndrome (MetS).

https://www.news-medical.net/news/20241127/Understanding-the-pathophysiological-relationship-between-OSA-and-metabolic-syndrome.aspx

Obe-cel demonstrates strong efficacy and safety in treating leukemia

https://www.news-medical.net/news/20241127/Obe-cel-demonstrates-strong-efficacy-and-safety-in-treating-leukemia.aspx

New HIV prevention injection offers 96% protection

https://www.news-medical.net/news/20241127/New-HIV-prevention-injection-offers-9625-protection.aspx

Specific HRT tablets linked to increased risk of heart disease and blood clots- hormone replacement therapy (HRT)

https://www.news-medical.net/news/20241128/Specific-HRT-tablets-linked-to-increased-risk-of-heart-disease-and-blood-clots.aspx

Flaws in study design may limit detection of cognitive effects in diet trials

https://www.news-medical.net/news/20241128/Flaws-in-study-design-may-limit-detection-of-cognitive-effects-in-diet-trials.aspx

Expert explores the expanding applications of GLP1 therapies

https://www.news-medical.net/news/20241128/Expert-explores-the-expanding-applications-of-GLP1-therapies.aspx

How different types of bread impact cancer risk

https://www.news-medical.net/news/20241120/How-different-types-of-bread-impact-cancer-risk.aspx?utm_source=news_medical_newsletter&utm_medium=email&utm_campaign=breast_cancer_newsletter_25_november_2024

Gut-liver metabolism plays a surprising role in liver scarring A liver enzyme affects fibrosis progression by altering metabolism of the sugar trehalose in the gut.

https://www.drugdiscoverynews.com/gut-liver-metabolism-plays-a-surprising-role-in-liver-scarring-16150

Gene therapy for pain treatment Using a gene therapy approach, researchers relieved pain behaviors in mice and tested the approach in human cells.

https://www.drugdiscoverynews.com/gene-therapy-for-pain-treatment-15895?utm_campaign=DDN_Newsletter_Dose&utm_medium=email&_hsenc=p2ANqtz-_L7ClQyswIEwjAHZfPOS_ubs-X5Xq6B8QxXVv3zsmfEKJxy8ai5AFk_K72sgVvrPbXRnEYsZBnVBTfnGT5ywQQCIYZSA&_hsmi=336108477&utm_content=336108477&utm_source=hs_email

A gene therapy hope for halting Huntington’s disease A one-time gene therapy aims to stop Huntington's disease at its source. But first, it has to survive clinical trials.

https://www.drugdiscoverynews.com/a-gene-therapy-hope-for-halting-huntington-s-disease-15759?utm_campaign=DDN_Newsletter_Dose&utm_medium=email&_hsenc=p2ANqtz-8oZNg1W0I6h3gasnhJ1yKwF3L3QqaIx4OvXotLo9HMmngWMFzYJXlzEx_udpeXtrPJUpxvFNKR4FKhSroFQmguY9ghbg&_hsmi=336108477&utm_content=336108477&utm_source=hs_email

Targeting Rett syndrome at the source Rett syndrome currently has no cure. Now, innovations in gene therapy bring the possibility of treating the root cause of the disease closer than ever before.

https://www.drugdiscoverynews.com/targeting-rett-syndrome-at-the-source-16151?utm_campaign=DDN_Newsletter_Dose&utm_medium=email&_hsenc=p2ANqtz-_VdFrkOzSwW_jvau5LKQjgtPG97oHUaYQHnxbhNoriyKe3YPK1g6obw2ydWP69Xc2Hiu2RDB1wnVeX2b7uUhxl9SYdZw&_hsmi=336108477&utm_content=336108477&utm_source=hs_email

ASH 2024 Myeloma Studies: My Top 10 Picks Manni Mohyuddin, MD November 27, 2024

https://www.medscape.com/s/viewarticle/ash-2024-myeloma-studies-my-top-10-picks-2024a1000llk

Can Popular Weight Loss Drugs Lower Cancer Risk? Amy Norton November 25, 2024

https://www.medscape.com/viewarticle/can-popular-weight-loss-drugs-lower-cancer-risk-2024a1000lg1

Merkel Cell Carcinoma Risk Factors: UV Radiation and Merkel Cell Polyomavirus Account for Most US Cases Edited by Gargi Mukherjee November 27, 2024

https://www.medscape.com/viewarticle/merkel-cell-carcinoma-risk-factors-uv-radiation-and-merkel-2024a1000llq

From Mindful Practice to Meaningful Planning: A New Path for Advanced Cancer Care? Edited by Carol Cruzan Morton November 28, 2024

https://www.medscape.com/viewarticle/mindful-practice-meaningful-planning-new-path-advanced-2024a1000lop

Biden–Harris Administration Expands Access to Life-Saving Organ Transplants Through HOPE Act Reform

https://www.hiv.gov/blog/biden-harris-administration-expands-access-to-life-saving-organ-transplants-through-hope-act-reform?j=2555962&sfmc_sub=6992026&l=6498_HTML&u=61521309&mid=100006181&jb=0

miércoles, 27 de noviembre de 2024

Two cases of type I sialidosis and a literature review Authors:Yuan Ding, Ming Cheng and Chunxiu Gong

https://ojrd.biomedcentral.com/

People With Lived/Living Experience of Substance Use Workgroup

https://nida.nih.gov/about-nida/advisory-boards-groups/national-advisory-council-drug-abuse-nacda/council-workgroups?utm_source=SAMHSA&utm_campaign=ae5bb06a00-EMAIL_CAMPAIGN_2024_11_25_11_23&utm_medium=email&utm_term=0_-ae5bb06a00-167840245

NCCIH 25th Anniversary Symposium to Explore Whole Person Health on December 2, 2024 November 26, 2024

https://www.nccih.nih.gov/research/blog/nccih-25th-anniversary-symposium-to-explore-whole-person-health-on-december-2-2024?nav=govd

Canada Takes One Health Approach to Antimicrobial Resistance Carolyn Crist November 27, 2024

https://www.medscape.com/viewarticle/canada-takes-one-health-approach-antimicrobial-resistance-2024a1000lml

Paying Forward, Giving Back, and Being All the Better for It Dina Cheney November 27, 2024

https://www.medscape.com/viewarticle/paying-forward-giving-back-and-being-all-better-it-2024a1000lmk

Ontario ED Staffing Struggles Highlight Chronic Shortfall Kerry Dooley Young November 27, 2024

https://www.medscape.com/viewarticle/ontario-ed-staffing-struggles-highlight-chronic-shortfall-2024a1000lmp

EoE: Which First-Line Treatments Are Most Cost-Effective? Megan Brooks November 27, 2024

https://www.medscape.com/viewarticle/eoe-which-first-line-treatments-are-most-cost-effective-2024a1000lmr

Eating More Red Meat Could Increase Type 2 Diabetes Risk Marilynn Larkin November 27, 2024

https://www.medscape.com/viewarticle/eating-more-red-meat-could-increase-type-2-diabetes-risk-2024a1000lmt

Microplastics Have Been Found in the Human Brain. Now What? Deborah Brauser November 27, 2024

https://www.medscape.com/viewarticle/microplastics-have-been-found-human-brain-now-what-2024a1000ln0

Diet Matters in Prostate Cancer, but It’s Complicated Jennie Smith November 27, 2024

https://www.medscape.com/viewarticle/diet-matters-prostate-cancer-its-complicated-2024a1000ln1

How Much Water Should We Drink in a Day? F. Perry Wilson, MD, MSCE

https://www.medscape.com/viewarticle/how-much-water-should-we-drink-day-2024a1000lgp

Wearable Devices for Parkinson’s Disease: The Future Is Here Patrice Wendling November 26, 2024

https://www.medscape.com/viewarticle/wearable-devices-parkinsons-disease-future-here-2024a1000ljg

Inequity complicates care for children with tracheostomies

https://innovationdistrict.childrensnational.org/inequity-complicates-care-for-children-with-tracheostomies/

You are taking Ozempic or Wegovy and aren’t losing weight? 20% of patients are in the same boat. Here’s why JoNel Aleccia | November 26, 2024

https://geneticliteracyproject.org/2024/11/26/you-are-taking-ozempic-or-wegovy-and-arent-losing-weight-20-of-patients-are-in-the-same-boat-heres-why/?mc_cid=d33540b921&mc_eid=b73600b7ac

AI will influence human evolution. Here’s how EurekAlert | November 26, 2024

https://geneticliteracyproject.org/2024/11/26/ai-will-influence-human-evolution-heres-how/?mc_cid=d33540b921&mc_eid=b73600b7ac

Characterizing what human sensory nerves can sense

https://www.nih.gov/news-events/nih-research-matters/characterizing-what-human-sensory-nerves-can-sense

Liver-brain communication affects eating patterns and obesity

https://www.nih.gov/news-events/nih-research-matters/liver-brain-communication-affects-eating-patterns-obesity

How sleep leads to healing after heart attack

https://www.nih.gov/news-events/nih-research-matters/how-sleep-leads-healing-after-heart-attack

How Alzheimer's Changes the Brain

Music and Health: What You Need To Know Can music be good for you?

https://www.nccih.nih.gov/health/music-and-health-what-you-need-to-know?nav=govd

martes, 26 de noviembre de 2024

How neural and hormonal gut-brain communication shapes metabolism and health

https://www.news-medical.net/news/20241125/How-neural-and-hormonal-gut-brain-communication-shapes-metabolism-and-health.aspx

Cyclosporin H Improves the Transduction of CD34+ Cells with an Anti-Sickling Globin Vector, a Possible Therapeutic Approach for Sickle Cell Disease

https://www.liebertpub.com/doi/10.1089/hum.2024.098?utm_campaign=HUM+PR+November+19+2024&utm_content=A+New+Strategy+to+Enhance+Gene+Therapy+for+Sickle+Cell+Disease&utm_term=&utm_medium=email&utm_source=Adestra

Human Tumor Atlases Provide Important Insights into How Cancer Tumors Develop and Spread Posted on November 21st, 2024 by Dr. Monica M. Bertagnolli

https://directorsblog.nih.gov/2024/11/21/human-tumor-atlases-provide-important-insights-into-how-cancer-tumors-develop-and-spread/

Clinical and functional assessment of SARS-CoV-2 sequelae among young marines – a panel study

https://www.thelancet.com/journals/lanam/article/PIIS2667-193X(24)00236-9/fulltext?dgcid=hubspot_update_feature_updatealerts_lanam&utm_campaign=update-lanam&utm_medium=email&_hsenc=p2ANqtz--nO6foof0BlbANgE8RAR-RzZ5no-Pcr7_ASlugdGBmKtdwZwEL4wB4ovRl3Mk2SJ6YWKeTrzSN0SrUlL8JXSlv-5dpbg&_hsmi=335431906&utm_content=335232127&utm_source=hs_email

Meet Daisy: The AI grandmother who is fighting back against scammers Mack DeGeurin | Popular Science | November 25, 2024

https://geneticliteracyproject.org/2024/11/25/meet-daisy-the-ai-grandmother-who-is-fighting-back-against-scammers/?mc_cid=9f7d01c0a5&mc_eid=b73600b7ac

‘It’s a crime not to increase the population’: Idaho, Kansas, and Missouri’s unprecedented rationale for banning women from seeking an abortion Linda Greenhouse | New York Times | November 25, 2024

https://geneticliteracyproject.org/2024/11/25/its-a-crime-not-to-increase-the-population-idaho-kansas-and-missouris-unprecedented-rationale-for-banning-women-from-seeking-an-abortion/?mc_cid=9f7d01c0a5&mc_eid=b73600b7ac

Infections and immune-specific proteins may increase dementia risk and brain atrophy

https://www.nia.nih.gov/news/infections-and-immune-specific-proteins-may-increase-dementia-risk-and-brain-atrophy?&utm_source=nia-eblast&utm_medium=email&utm_campaign=general-20241125

Cognitive impairment and gender show more impact on driving cessation than dementia biomarkers

https://www.nia.nih.gov/news/cognitive-impairment-and-gender-show-more-impact-driving-cessation-dementia-biomarkers?&utm_source=nia-eblast&utm_medium=email&utm_campaign=general-20241125

Primary Care Providers Can Prescribe with Confidence (Videos)

https://www.fda.gov/drugs/prescribe-confidence/primary-care-providers-can-prescribe-confidence?utm_medium=email&utm_source=govdelivery#words In their own words: Internal medicine doctor Mina Tanaka, M.D. Dr. Tanaka says that many people believe prescribing medications for OUD require more know-how than other medications, but she hasn’t found that to be true. As a physician at Northern Navajo Medical Center in Shiprock, New Mexico, she has found that being a part of someone’s journey to stability is one of the most rewarding things she’s done as a physician. Hear more of her real-life experience prescribing medications for OUD (MOUD) in primary care and learn more about people whose lives have been changed through access to these medications. Watch Dr. Tanaka’s videos, see our previous testimonial videos, and share them with others on social media!

Spotlight on Herbs and Other Botanicals November 2024

https://www.nccih.nih.gov/health/providers/digest/spotlight-on-herbs-and-other-botanicals?nav=govdcd

Methamphetamine Awareness Day

https://www.samhsa.gov/blog/methamphetamine-awareness-day?utm_source=SAMHSA&utm_campaign=123acf7ee2-EMAIL_CAMPAIGN_2024_11_25_06_42&utm_medium=email&utm_term=0_-123acf7ee2-167840245

FDA approves drug for heart disorder caused by transthyretin-mediated amyloidosis

https://www.fda.gov/drugs/news-events-human-drugs/fda-approves-drug-heart-disorder-caused-transthyretin-mediated-amyloidosis?utm_medium=email&utm_source=govdelivery

Bird flu surges in several US states with reports of new outbreaks: 'Getting worse' Hawaii, California and Arizona report recent upticks in bird flu cases among animals and humans Angelica Stabile By Angelica Stabile Fox News Published November 19, 2024 4:49pm EST

Bird flu surges in several US states with reports of new outbreaks: 'Getting worse' Hawaii, California and Arizona report recent upticks in bird flu cases among animals and humans Angelica Stabile By Angelica Stabile Fox News Published November 19, 2024 4:49pm EST https://www.foxnews.com/health/bird-flu-surges-several-us-states-reports-new-outbreaks-getting-worse

Dementia risk could be linked to walking speed, study suggests A person's pace and gait could serve as another screening tool, say researchers By Amy McGorry Fox News Published November 21, 2024 6:00am EST

Dementia risk could be linked to walking speed, study suggests A person's pace and gait could serve as another screening tool, say researchers By Amy McGorry Fox News Published November 21, 2024 6:00am EST https://www.foxnews.com/health/dementia-risk-could-linked-walking-speed-study-suggests

'I'm a pharmacist, and I wouldn't take these 3 vitamin supplements' Some supplements are 'over-consumed' and 'don't have enough nutrients,' expert warns Angelica Stabile By Angelica Stabile Fox News Published November 21, 2024 10:00am EST

'I'm a pharmacist, and I wouldn't take these 3 vitamin supplements' Some supplements are 'over-consumed' and 'don't have enough nutrients,' expert warns Angelica Stabile By Angelica Stabile Fox News Published November 21, 2024 10:00am EST https://www.foxnews.com/health/pharmacist-wouldnt-take-vitamin-supplements

Clonazepam, popular anxiety-reducing drug, recalled nationwide for ‘possibly life-threatening’ error The medication's packaging was mislabeled with the incorrect strength, according to the FDA By Sarah Rumpf-Whitten Fox News Published November 22, 2024 1:26am EST | Updated November 22, 2024 1:31am EST

Clonazepam, popular anxiety-reducing drug, recalled nationwide for ‘possibly life-threatening’ error The medication's packaging was mislabeled with the incorrect strength, according to the FDA By Sarah Rumpf-Whitten Fox News Published November 22, 2024 1:26am EST | Updated November 22, 2024 1:31am EST https://www.foxnews.com/health/clonazepam-popular-anxiety-reducing-drug-recalled-nationwide-possibly-life-threatening-error

AI detects woman’s breast cancer after routine screening missed it: 'Deeply grateful' After mammogram came back 'normal,' artificial intelligence caught early cancer cells Angelica Stabile By Angelica Stabile Fox News Published November 22, 2024 2:27pm EST

AI detects woman’s breast cancer after routine screening missed it: 'Deeply grateful' After mammogram came back 'normal,' artificial intelligence caught early cancer cells Angelica Stabile By Angelica Stabile Fox News Published November 22, 2024 2:27pm EST https://www.foxnews.com/health/ai-detects-womans-breast-cancer-routine-screening-missed-deeply-grateful

Martha Stewart, 83, stays fit and flexible with this routine Celebrity trainer suggests exercises for older adults to stay 'strong and stable' Angelica Stabile By Angelica Stabile Fox News Published November 25, 2024 2:14pm EST

Martha Stewart, 83, stays fit and flexible with this routine Celebrity trainer suggests exercises for older adults to stay 'strong and stable' Angelica Stabile By Angelica Stabile Fox News Published November 25, 2024 2:14pm EST https://www.foxnews.com/health/martha-stewart-83-stays-fit-flexible-routine

Ozempic, Wegovy covered by Medicare and Medicaid under Biden admin proposal for anti-obesity GLP-1 drugs White House says without insurance coverage, anti-obesity drugs can cost ‘as much as $1,000 a month’ Greg Norman By Greg Norman Fox News Published November 26, 2024 7:40am EST

Ozempic, Wegovy covered by Medicare and Medicaid under Biden admin proposal for anti-obesity GLP-1 drugs White House says without insurance coverage, anti-obesity drugs can cost ‘as much as $1,000 a month’ Greg Norman By Greg Norman Fox News Published November 26, 2024 7:40am EST https://www.foxnews.com/health/ozempic-wegovy-covered-medicare-medicaid-biden-admin-proposal-anti-obesity-glp1-drugs

Glucose limitation protects cancer cells from apoptosis induced by pyrimidine restriction and replication inhibition

https://www.nature.com/articles/s42255-024-01166-w New insight into how cancer can beat chemo It’s known that chemotherapy doesn’t always work long-term for cancer patients, as tumor cells can expertly adapt to drugs. But less is known about how that happens. To find out, researchers scanned 3,000 cancer gene cells that are known to be involved with cell metabolism. They were particularly interested in how the level of nutrients in tumors can limit the effect of treatment. The study, published this morning in Nature, sheds light on how cells in glucose-limited tumors are already resistant to some drugs that aim to disrupt cancer metabolism. Some drugs work by preventing cancer cells from making molecules that are an essential part of RNA and DNA. Those molecules (called pyrimidines) are needed to make more food for the cell and to reproduce. Without them, cancer cells can quickly starve and die. But it turns out that in a low-glucose environment, a cancer cell will stretch out its food supplies, consuming what it already has on hand at a slower rate, leading to a slower death. In other experiments, researchers observed two proteins (BAX and BAK) that sit on the surface of the cancer cell mitochondria. When activated, those proteins disintegrate the powerhouse of the cell, leading to cell death. But low-glucose tumor microenvironments weren’t able to activate the proteins. It’s common for solid tumors to have limited glucose because the cells are eating it faster than they can import it, as STAT’s Angus Chen explained to me. The researchers hope the results could be used to develop more effective treatments in the future.

lunes, 25 de noviembre de 2024

Research identifies the brain's 'locus coeruleus' as key player in sleep cycles

https://www.news-medical.net/news/20241125/Research-identifies-the-brains-locus-coeruleus-as-key-player-in-sleep-cycles.aspx

The silent struggles of men’s mental health and suicide prevention

https://www.news-medical.net/news/20241125/The-silent-struggles-of-mene28099s-mental-health-and-suicide-prevention.aspx

New study offers insights into reliable Alzheimer's diagnosis

https://www.news-medical.net/news/20241125/New-study-offers-insights-into-reliable-Alzheimers-diagnosis.aspx

Do you have the right to be forgotten online? Our data is everywhere. Scrubbing it from the face of the Internet can be a tricky proposition depending on the laws where you live.

https://www.israel21c.org/do-you-have-the-right-to-be-forgotten-online/

Researchers develop breakthrough Covid-19 vaccine Needle-free nano-vaccine, cheap to produce, requires no refrigeration and is administered as nasal spray, making it accessible to developing nations.

https://www.israel21c.org/researchers-develop-breakthrough-covid-19-vaccine/

Decoding your bacterial language could cure your anxiety Israeli professor wins $1.2 million grant to support his study of how gut bacteria’s chemical signals may affect human behavior.

https://www.israel21c.org/decoding-your-bacterial-language-could-cure-your-anxiety/

Mikkel Højlund on antipsychotics polypharmacy November 12, 2024 • The Lancet Group

https://thelancetpsychiatry.buzzsprout.com/1391365/episodes/16065397-mikkel-hojlund-on-antipsychotics-polypharmacy?utm_campaign=infocusalerts-psychiatry&utm_medium=email&_hsenc=p2ANqtz-9DhQDfbkQpiJO2mAcQ0x-7fpiMR7s_9_5j0HgceABjH7b9OhB-Q0n_Jw504zPzoy1amqxg_rvceJMTVaBd26VbBn3Tkg&_hsmi=335346395&utm_content=335007414&utm_source=hs_email

Systems Matter: Why Systems Thinking is Essential for Bridging the Mental Health Research Implementation Gap mié, 04 dic 10:30 - 13:30 GMT-3

https://events.teams.microsoft.com/event/b065a1c0-bd3b-4d58-ae02-f1896c0d9d71@91a138ee-d6db-40d9-9ca7-44fcd132fa5e?utm_campaign=infocusalerts-psychiatry&utm_medium=email&_hsenc=p2ANqtz-__vgHA3EcDwb2VyrUigxKdNpqbEDV2J2VekymAnHtHIVPYgFk5KszEnE4dNe5SeIm9dgAdeZP-taTLSL9fwilCNeFYXg&_hsmi=335346395&utm_content=335007414&utm_source=hs_email

Dementia in the Western Pacific region: from risk reduction to care

https://www.thelancet.com/series/western-pacific-dementia-risk-reduction-and-care?dgcid=hubspot_email_infocusalerts-psychiatry_feature_lanwpcdementia24&utm_campaign=infocusalerts-psychiatry&utm_medium=email&_hsenc=p2ANqtz-9rnSwFIvLcLaEsPUDmZobTwsX4ZMIASA9CIf6pRBizkYPcoNX_SHrspgD3fBC-yJI1BF6LP0Kdv_nMdoPSEk7SInkLIw&_hsmi=335346395&utm_content=335007414&utm_source=hs_email

Independent and joint associations of cardiometabolic multimorbidity and depression on cognitive function: findings from multi-regional cohorts and generalisation from community to clinic

https://www.thelancet.com/journals/lanwpc/article/PIIS2666-6065(24)00192-5/fulltext?dgcid=hubspot_email_infocusalerts-psychiatry_feature&utm_campaign=infocusalerts-psychiatry&utm_medium=email&_hsenc=p2ANqtz-9-mP5EcDeawALJ73a0fMmb8X0qfuJtVQkmGTR6lXtvbWTJnTRIdx3-RBZ1iCMs-ow8_OKerydC8shpafXIMYnRBPD5gw&_hsmi=335346395&utm_content=335007414&utm_source=hs_email

Consensus statement helps assess patient readiness for gene therapy in sickle cell disease

https://www.healio.com/news/hematology-oncology/20241002/consensus-statement-helps-assess-patient-readiness-for-gene-therapy-in-sickle-cell-disease

Why gene therapy for sickle cell is slow to catch on with patients By Deena Beasley

https://www.reuters.com/business/healthcare-pharmaceuticals/why-gene-therapy-sickle-cell-is-slow-catch-with-patients-2024-09-28/

Open Phase I and II Clinical Trials

https://www.childrensnational.org/get-care/departments/oncology/clinical-trials

Meet Dr. Andrew Campbell: Trailblazing treatment for patients with sickle cell disease

https://innovationdistrict.childrensnational.org/meet-dr-andrew-campbell/

Closing the ‘Valley of Death’: Pioneering – and paying for – new therapies

https://innovationdistrict.childrensnational.org/pioneering-and-paying-for-new-therapies/

Can Planning Models Enhance Radiation Therapy for Cancer? Edited by Gargi Mukherjee November 25, 2024

https://www.medscape.com/viewarticle/can-planning-models-enhance-radiation-therapy-cancer-2024a1000lef

Expert Consensus Provides Clinical Guidance for Treating Hair Loss With Low-Dose Oral Minoxidil John Jesitus November 25, 2024

https://www.medscape.com/viewarticle/expert-consensus-provides-clinical-guidance-treating-hair-2024a1000ler

MASLD and MetALD Linked to Increased Cancer Risk Edited by Javed Choudhury November 25, 2024

Metabolic dysfunction–associated steatotic liver disease (MASLD) https://www.medscape.com/viewarticle/masld-and-metald-linked-increased-cancer-risk-2024a1000lfj

Are Maternal Illnesses During Pregnancy Linked to Childhood Cancer? Miriam Davis, PhD November 18, 2024

https://www.medscape.com/s/viewarticle/are-maternal-illnesses-during-pregnancy-linked-childhood-2024a1000ksm

PFAS-Contaminated Drinking Water and Hormone Receptor-Positive Breast Cancer? Miriam Davis, PhD November 22, 2024

https://www.medscape.com/s/viewarticle/pfas-contaminated-drinking-water-and-hormone-receptor-2024a1000l3o

domingo, 24 de noviembre de 2024

Sayer Vision Research Lecture and Award 2024: Marla Feller, PhD December 9, 2024 3:00 PM to 4:00 PM ET

https://www.nei.nih.gov/about/news-and-events/events/sayer-vision-research-lecture-and-award-2024-marla-feller-phd

New Model of Neuronal Circuit Provides Insight on Eye Movement

https://news.weill.cornell.edu/news/2024/11/new-model-of-neuronal-circuit-provides-insight-on-eye-movement

NIH-led scientific team defines elements of brain-based visual impairment in children Research needed to establish best diagnostic and management strategies for increasingly common condition

https://www.nei.nih.gov/about/news-and-events/news/nih-led-scientific-team-defines-elements-brain-based-visual-impairment-children

Clinical trials involving animals can have a 99.6% failure rate in some instances sparking researchers to find alternatives Rachel Nuwar | Scientific American | November 22, 2024

https://geneticliteracyproject.org/2024/11/22/90-percent-of-novel-drugs-that-work-in-animal-models-fail-in-human-clinical-trials-alternatives-are-in-development/?mc_cid=59df60ceec&mc_eid=b73600b7ac

The queasy possibility that humans and AI could ‘evolve’ in tandem Lance Eliot | Forbes | November 22, 2024

https://geneticliteracyproject.org/2024/11/22/the-queasy-possibility-that-humans-and-ai-could-evolve-in-tandem/?mc_cid=59df60ceec&mc_eid=b73600b7ac

Born athletes? Identical twin studies show the balance of genetics vs training Alex Hutchinson | Outside | November 22, 2024

https://geneticliteracyproject.org/2024/11/22/born-athletes-identical-twin-studies-show-the-balance-of-genetics-vs-training/?mc_cid=59df60ceec&mc_eid=b73600b7ac

Suvankar Pal on the motor neuron disease trial MND-SMART October 16, 2024 • The Lancet Group

https://www.buzzsprout.com/1391383/episodes/15922211-suvankar-pal-on-the-motor-neuron-disease-trial-mnd-smart?utm_campaign=infocusalerts-neurology&utm_medium=email&_hsenc=p2ANqtz-9cxOBSsET9-OpbR4GFo2tqdHL5_Usvb6WgmCIQ1xt8TNljkGe0yC8mBk6HBkX8h1KEz31FBaAZb-shdhIfbNZoBVyAng&_hsmi=335245262&utm_content=335007849&utm_source=hs_email

Bridging the women's health gap: addressing inequalities in medical research and care Available On Demand 1 hour, 27 minutes

https://event.on24.com/wcc/r/4664017/1DDCAFFC5B9F1BCD12DAA940CE3EB93A?partnerref=infocusalerts-neurology_feature_womenhealth_ondemand&utm_campaign=infocusalerts-neurology&utm_medium=email&_hsenc=p2ANqtz-9yV9n_DKjQpSIOoxUX4L8G9kLzzfrO6HIbkz2P31djJ9m3UPyFFWQVx4bBGeGjLl9pREOseeLwm4Hix6mTAwZjsEB0GA&_hsmi=335245262&utm_content=335007849&utm_source=hs_email

Sensitivity and specificity of a seed amplification assay for diagnosis of multiple system atrophy: a multicentre cohort study Yihua MaCarly M FarrisSandrina WeberSebastian SchadeHieu NguyenAlexandra Pérez-Sorianoand others The Lancet NeurologyVol. 23No. 12p1225–1237

https://www.thelancet.com/collections/neurology?dgcid=hubspot_email_infocusalerts-neurology_feature&parent=001585&startPage=&ContentItemType=fla&utm_campaign=infocusalerts-neurology&utm_medium=email&_hsenc=p2ANqtz--X0qmTeOrVdhI6w-xViF0tBwMnkxRPcsh8irfI0RZtq03zdI0IU5bCm9Pth59ngnpFoIutc3eyVz6iwkdFmsS8UVqPdA&_hsmi=335245262&utm_content=335007849&utm_source=hs_email

Dementia-related stigma is still pervasive The Lancet Neurology

https://www.thelancet.com/journals/laneur/issue/vol23no11/PIIS1474-4422(24)X0011-3

Safety and efficacy of memantine and trazodone versus placebo for motor neuron disease (MND SMART): stage two interim analysis from the first cycle of a phase 3, multiarm, multistage, randomised, adaptive platform trial

https://www.thelancet.com/journals/laneur/article/PIIS1474-4422(24)00326-0/fulltext?dgcid=hubspot_email_infocusalerts-neurology_feature&utm_campaign=infocusalerts-neurology&utm_medium=email&_hsenc=p2ANqtz-844UG1Bd-3gaT0CqpZFosJsSQCF98c6JAvt2cJVaetM5XGSnnc_dWiynXYzogDHYyIWINKSPYn-_UQOgl9UvSMBdb7Tg&_hsmi=335245262&utm_content=335007849&utm_source=hs_email

Clinical effectiveness of DREAMS START (Dementia Related Manual for Sleep; Strategies for Relatives) versus usual care for people with dementia and their carers: a single-masked, phase 3, parallel-arm, superiority randomised controlled trial

https://www.thelancet.com/journals/lanhl/article/PIIS2666-7568(24)00161-2/fulltext?dgcid=hubspot_email_infocusalerts-neurology_feature&utm_campaign=infocusalerts-neurology&utm_medium=email&_hsenc=p2ANqtz-9DK5zOj7XKcq6lYaqLJqyj6USc7esU9m9znQuQX0NlyK67W0mwz3LLJRsjhdLKY06Ps5FtxfkiiXsm_w7mU22UOydHjw&_hsmi=335245262&utm_content=335007849&utm_source=hs_email

semaglutide (Rx) US Drug Spotlight

https://reference.medscape.com/drug/ozempic-rybelsus-wegovy-semaglutide-1000174?ecd=mkm_ret_241123_mscpmrk_MOB_e5_etid7020700&uac=148436CN&impID=7020700

Nov 15, 2024 This Week in Cardiology Podcast John M. Mandrola, MD November 15, 2024

https://www.medscape.com/viewarticle/1001920?ecd=mkm_ret_241123_mscpmrk_MOB_e5_etid7020700&uac=148436CN&impID=7020700#vp_4

Treating Obesity May Reduce Pelvic Organ Prolapse Risk Edited by Shrabasti Bhattacharya November 06, 2024

https://www.medscape.com/viewarticle/treating-obesity-may-reduce-pelvic-organ-prolapse-risk-2024a1000k90?ecd=mkm_ret_241123_mscpmrk_MOB_e5_etid7020700&uac=148436CN&impID=7020700

Telehealth Firm Hims & Hers Launches Weight-loss Drug Shortage Tracker November 13, 2024

https://www.medscape.com/s/viewarticle/telehealth-firm-hims-hers-launches-weight-loss-drug-shortage-2024a1000kqc?ecd=mkm_ret_241123_mscpmrk_MOB_e5_etid7020700&uac=148436CN&impID=7020700

Obesity in the US Projected to Skyrocket by 2050 Miriam E. Tucker November 14, 2024

https://www.medscape.com/viewarticle/obesity-us-projected-skyrocket-2050-2024a1000kvb?ecd=mkm_ret_241123_mscpmrk_MOB_e5_etid7020700&uac=148436CN&impID=7020700

Could Weight Loss Injections Replace Obesity Surgery? Ute Eppinger November 14, 2024

https://www.medscape.com/viewarticle/could-weight-loss-injections-replace-obesity-surgery-2024a1000kk1?ecd=mkm_ret_241123_mscpmrk_MOB_e5_etid7020700&uac=148436CN&impID=7020700

Side Effects of GLP-1 Drugs: What Doctors Should Know Debbie Koenig November 21, 2024

https://www.medscape.com/viewarticle/side-effects-glp-1-drugs-what-doctors-should-know-2024a1000l8r?ecd=mkm_ret_241123_mscpmrk_MOB_e5_etid7020700&uac=148436CN&impID=7020700

Outpatient CAR T: Safe, Effective, Accessible Randy Dotinga November 01, 2024

https://www.medscape.com/viewarticle/outpatient-car-t-safe-effective-accessible-2024a1000jze?ecd=mkm_ret_241124_mscpmrk_hem_top-content_etid7019414&uac=148436CN&impID=7019414

sábado, 23 de noviembre de 2024

New PET probe tracks CAR T cell therapy in real time A new method for tracking CAR T cells in patients with blood cancers relies on a probe that binds directly to the therapeutic cells’ antigen receptor.

https://www.drugdiscoverynews.com/new-pet-probe-tracks-car-t-cell-therapy-in-real-time-16139

Brain waves synchronize when enjoying music, lessening depression Synchrony between the reward system and the auditory cortex in the brain underlies the positive effects of music on mood.

https://www.drugdiscoverynews.com/brain-waves-synchronize-when-enjoying-music-lessening-depression-16141

Decoding cell behavior and disease with AI and single-cell transcriptomics Machine learning paired with single-cell analysis helps scientists identify pathways that cause disease and potential therapeutics.

https://www.drugdiscoverynews.com/leveraging-artificial-intelligence-and-single-cell-transcriptomics-to-decode-cel-15269?utm_campaign=DDN_Newsletter_Dose&utm_medium=email&_hsenc=p2ANqtz---ELpaVKbNRNbky2Y9XlHsGp47OyzDhTWZtuD5g46KBHDPNCUUmPfYMzIm8A9wBcLE7QzS8Q49L0QsrRIzQnjuujawCA&_hsmi=335220845&utm_content=335220845&utm_source=hs_email

AI finds new uses for old drugs Researchers built a framework to purposefully identify drug candidates for repurposing.

https://www.drugdiscoverynews.com/ai-finds-new-uses-for-old-drugs-15222?utm_campaign=DDN_Newsletter_Dose&utm_medium=email&_hsenc=p2ANqtz-9U5b_XeKISIHjBI_BBIU5WVxmKYNp1KDKEPP8hAVyVDKwQFZReNlM43pMnT5dw5rggoNiI8MzhZ3exsXRrNw_htoDRZg&_hsmi=335220845&utm_content=335220845&utm_source=hs_email

Rediscovering forgotten drugs with new AI tools As scientific output grows, the risk of a promising drug getting lost increases, but advances in artificial intelligence and machine learning may prevent that.

https://www.drugdiscoverynews.com/rediscovering-forgotten-drugs-with-new-ai-tools-16142?utm_campaign=DDN_Newsletter_Dose&utm_medium=email&_hsenc=p2ANqtz-_kDmcbidOu2QvOqc_S7bUk6YSG7tmSszhhYT-ONiDArhmFgEv7VwguvrOchUA7_10xIrm18FOq53VGrpQ_uJGb10YmhQ&_hsmi=335220845&utm_content=335220845&utm_source=hs_email

HIDDEN DANGERS OF WEIGHT LOSS DRUGS

Hidden Dangers of Weight Loss Drugs By Ivanhoe Broadcast News on December 1, 2024 https://www.ivanhoe.com/?p=34584&preview=1&_ppp=a2aa75830f

NATURAL TREATMENTS FOR TMJ

TMJ: Natural Treatments By Ivanhoe Broadcast News on December 1, 2024 https://www.ivanhoe.com/?p=34581&preview=1&_ppp=25656c0708

CAUTION IDENTIFIES CANCER RISKS

Caution Identifies Cancer Risks By Ivanhoe Broadcast News on November 30, 2024 https://www.ivanhoe.com/?p=34578&preview=1&_ppp=61afb692d8

KIDS AND CANNABIS: A DEADLY COMBINATION

Kids and Cannabis: A Dangerous Combination By Ivanhoe Broadcast News on November 30, 2024 https://www.ivanhoe.com/?p=34575&preview=1&_ppp=437291b97b

LONG COVID: UNRAVELING THE MYSTERY

Long COVID: Unraveling the Mystery By Ivanhoe Broadcast News on November 29, 2024 https://www.ivanhoe.com/?p=34600&preview=1&_ppp=741209a886

FROM STROKE TO STRENGTH: BUILDING MENTAL RESILIENCE

From Stroke to Strength: Building Mental Resilience By Ivanhoe Broadcast News on November 28, 2024 https://www.ivanhoe.com/?p=34597&preview=1&_ppp=a70475c3de

A GUT FEELING: MICROBIOME IMPACT ON MIND AND BODY

A Gut Feeling: Microbiome Impact on Mind and Body By Ivanhoe Broadcast News on November 27, 2024 https://www.ivanhoe.com/?p=34594&preview=1&_ppp=aa15222edf

THE ULTIMATE QUESTION: HOW DOES BREAST CANCER START?

Breast Cancer: How Does it Start? By Ivanhoe Broadcast News on November 26, 2024 https://www.ivanhoe.com/?p=34591&preview=1&_ppp=c4124a934e

RECOVER FROM HIP SURGERY SIX DAYS SOONER

Recover From Hip Replacement Six Days Sooner By Ivanhoe Broadcast News on November 25, 2024 https://www.ivanhoe.com/?p=34587&preview=1&_ppp=0042c35cb3

Parkinson's patients breathe differently, Israeli study discovers Weizmann Institute researchers in collaboration with the Ichilov Medical Center find that people with Parkinson's disease take longer and more steady breaths and claim this will help early diagnosis Dr. Michal Andelman-Gur, Prof. Noam Sobel, Prof. Tanya Gurevich|11.21.24 | 11:51

https://www.ynetnews.com/health_science/article/s1vt00tsgkx

Controlling blood sugar may slow brain aging - study One’s chronological age is the number of years lived, while brain age indicates the brain’s actual health. They are often not identical. By JUDY SIEGEL-ITZKOVICH NOVEMBER 17, 2024 01:03

https://www.jpost.com/health-and-wellness/article-829378

Israel to expand medical device access in periphery to boost healthcare Israel's Health Committee approves major medical imaging expansion with six CT and ten MRI machines for peripheral regions, addressing critical equipment shortages. By WALLA! NOVEMBER 18, 2024 00:16 Updated: NOVEMBER 18, 2024 00:17

https://www.jpost.com/health-and-wellness/article-829552

Breakthrough study at Tel Aviv University reveals new mechanisms behind autism Tel Aviv University researchers have identified new brain mechanisms in genetic autism, offering potential new pathways for future treatments. By RAQUEL GUERTZENSTEIN FROHLICH NOVEMBER 21, 2024 08:42

https://www.jpost.com/health-and-wellness/article-830022

Dietary choices could slash brain aging: new study explains how A Ben-Gurion University study reveals the green Mediterranean diet can slow brain aging by 50%, linking glycemic control and nutrition to reduced cognitive decline. By VERONICA NEIFAKH / THE MEDIA LINE NOVEMBER 22, 2024 22:00

https://www.jpost.com/health-and-wellness/article-830324

New drug-delivery stent could revolutionize women’s health OCON Therapeutics invented a novel technology that allows for intrauterine drug delivery that could affect the wellbeing of women worldwide.

https://www.israel21c.org/new-drug-delivery-stent-could-revolutionize-womens-health/

viernes, 22 de noviembre de 2024

Tackling obesity: drugs are only part of the solution The Lancet Gastroenterology & Hepatology

https://www.thelancet.com/journals/langas/issue/vol9no12/PIIS2468-1253(24)X0011-4

International expert guidance for defining and monitoring small bowel strictures in Crohn's disease on intestinal ultrasound: a consensus statement

https://www.thelancet.com/journals/langas/article/PIIS2468-1253(24)00265-6/abstract?utm_campaign=update-langas&utm_medium=email&dgcid=hubspot_update_feature_updatealerts_langas&_hsenc=p2ANqtz-8gzcADjnQ16MmJtQXdGrnbXseaB-Lv8SD3Oj-P66EefVnYtTFY6Hx_Tti9i84-0rbXJOJCY7fMvJuBmj9kwwLeX2bW_A&_hsmi=334662119&utm_content=334644273&utm_source=hs_email

Viewpoint: Overhauling the teaching of genetics is necessary to eliminate the concept of race Elaine Guevara | Sapiens | November 21, 2024

https://geneticliteracyproject.org/2024/11/21/viewpoint-overhauling-the-teaching-of-genetics-is-necessary-to-eliminate-the-concept-of-race/?mc_cid=4d51a4fa7b&mc_eid=b73600b7ac

Does eating ultra-processed foods speed up aging? Kelsey Costa | Medical News Today | November 21, 2024

https://geneticliteracyproject.org/2024/11/21/does-eating-ultra-processed-foods-speed-up-aging/?mc_cid=4d51a4fa7b&mc_eid=b73600b7ac

No-burp syndrome: 20,000 people on Reddit’s “I can’t belch” subreddit spread the word of a Botox cure Rae Ellen Bichell | November 21, 2024

https://geneticliteracyproject.org/2024/11/21/no-burp-syndrome-20000-people-on-reddits-i-cant-belch-subreddit-spread-the-word-of-a-botox-cure/?mc_cid=4d51a4fa7b&mc_eid=b73600b7ac

Trial Results Support SBRT as a Standard Option for Some Prostate Cancers

https://www.cancer.gov/news-events/cancer-currents-blog/2024/prostate-cancer-sbrt-effective-safe?cid=eb_govdel

NIAID Researchers Find Anti-HIV Antibodies Affect Immune Responses When Delivered During Acute Infection

https://www.hiv.gov/blog/niaid-researchers-find-anti-hiv-antibodies-affect-immune-responses-when-delivered-during-acute-infection?j=2551008&sfmc_sub=6992026&l=6498_HTML&u=61350263&mid=100006181&jb=0

SAD | Exercise and Physical Activity | Pain Reduction | Anxiety | Bone Density

https://content.govdelivery.com/accounts/USNIH/bulletins/3c1ed89?reqfrom=share

Osteoporosis: What you need to know Spot the signs and get advice for living with this ‘silent’ bone disease

https://magazine.medlineplus.gov/article/osteoporosis-what-you-need-to-know?utm_medium=email&utm_source=govdelivery

My mammogram was ‘abnormal’—what do I do next?

https://magazine.medlineplus.gov/article/my-mammogram-was-abnormalwhat-do-i-do-next?utm_medium=email&utm_source=govdelivery

Stages I-III Screen-Detected CRC Boosts Disease-Free Survival Rates Edited by Javed Choudhury November 22, 2024

https://www.medscape.com/viewarticle/stages-i-iii-screen-detected-crc-boosts-disease-free-2024a1000lbr

Lung Cancer Survival Is Improving, Though State Rates Vary Jennie Smith November 21, 2024

https://www.medscape.com/viewarticle/lung-cancer-survival-improving-though-state-rates-vary-2024a1000l9r

Checkpoint Inhibitors Seem Safe in Autoimmune Disease Miriam E. Tucker November 21, 2024

https://www.medscape.com/viewarticle/checkpoint-inhibitors-seem-safe-autoimmune-disease-2024a1000l82

When Cancer Therapy Affects the Skin: A Guide for Clinicians Carolin Hellerich November 22, 2024

https://www.medscape.com/viewarticle/when-cancer-therapy-affects-skin-guide-clinicians-2024a1000lbh

FDA Approves Bispecific HER2 Antibody for Biliary Tract Cancer M. Alexander Otto, PA, MMS November 21, 2024

https://www.medscape.com/viewarticle/fda-approves-bispecific-her2-antibody-biliary-tract-cancer-2024a1000lac

Stand-Alone Adjuvant Immunotherapy for Early TNBC? M. Alexander Otto, PA, MMS November 22, 2024

https://www.medscape.com/viewarticle/stand-alone-adjuvant-immunotherapy-early-tnbc-2024a1000lbs

As GLP-1 Use Surges, Clinicians Weigh Benefits and Risks Batya Swift Yasgur, MA, LSW November 22, 2024

https://www.medscape.com/viewarticle/glp-1-use-surges-clinicians-weigh-benefits-and-risks-2024a1000lb5

‘Watershed Moment’: Semaglutide Shown to Be Effective in MASH Carolyn Crist November 21, 2024

https://www.medscape.com/viewarticle/watershed-moment-semaglutide-shown-be-effective-mash-2024a1000l8i

The Strange Untold Story of How Science Solved Narcolepsy Laura Tedesco November 21, 2024

https://www.medscape.com/viewarticle/strange-untold-story-how-science-solved-narcolepsy-2024a1000l8v

FDA grants accelerated approval to zanidatamab-hrii for previously treated unresectable or metastatic HER2-positive biliary tract cancer

https://www.fda.gov/drugs/resources-information-approved-drugs/fda-grants-accelerated-approval-zanidatamab-hrii-previously-treated-unresectable-or-metastatic-her2

jueves, 21 de noviembre de 2024

Switching off drug-resistant cancer

Switching off drug-resistant cancer: With their eclectic mix of mutations, tumors often survive drug treatment. In a new study, researchers found a way to use cancer’s evolutionary potential against it, destroying drug-resistant tumors in animals.

Viewpoint: The story of RP11, whose DNA mostly defines the first genetic blueprint of humanity Misha Angrist | November 19, 2024

https://geneticliteracyproject.org/2024/11/19/viewpoint-the-story-of-rp11-whose-dna-mostly-defines-the-first-genetic-blueprint-of-humanity/?mc_cid=cddafd9834&mc_eid=b73600b7ac

Outcomes that matter to patients with cancer: living longer and living better

https://www.thelancet.com/journals/eclinm/article/PIIS2589-5370(24)00412-7/fulltext?dgcid=hubspot_update_feature_updatealerts_eclinm&utm_campaign=update-eclinm&utm_medium=email&_hsenc=p2ANqtz-8hS_nE8iCiL49w9nJNnuM2NkAHxvZ6PgBByaOzDQCYXnrTc1fxYFUW9-7TlzViCkvOkEbDXNheDa_bYfl3l5d1n4L1Aw&_hsmi=334859646&utm_content=334840438&utm_source=hs_email Health inequalities in cancer care: a literature review of pathways to diagnosis in the United Kingdom https://www.thelancet.com/journals/eclinm/article/PIIS2589-5370(24)00443-7/fulltext?dgcid=hubspot_update_feature_updatealerts_eclinm&utm_campaign=update-eclinm&utm_medium=email&_hsenc=p2ANqtz-8vqbS_x4p8TZFIfHAp_4At29RUwXvSero_07sP8g35I1EBTjVhxPsTaDlPc1V8KBmSbyFyZ7TS__jBV8nErFwB6byj4A&_hsmi=334859646&utm_content=334840438&utm_source=hs_email Advancing patient-centric care: integrating patient reported outcomes for tolerability assessment in early phase clinical trials – insights from an expert virtual roundtable https://www.thelancet.com/journals/eclinm/article/PIIS2589-5370(24)00417-6/fulltext?dgcid=hubspot_update_feature_updatealerts_eclinm&utm_campaign=update-eclinm&utm_medium=email&_hsenc=p2ANqtz--knM6DQM5f1RJrz2sJweY1Z0NOiXKfRPyv_ZKolfgq68L3IO-D9AYwyggtiSUEoFesVk4_ZjxdjYy6d2QvsSXQjLBWAw&_hsmi=334859646&utm_content=334840438&utm_source=hs_email

Endometriosis and uterine fibroids and risk of premature mortality: prospective cohort study

https://www.bmj.com/content/387/bmj-2023-078797?utm_campaign=morning_rounds&utm_medium=email&_hsenc=p2ANqtz-9WYMoedVXvORQTbtJVm8YA31oln_agZxAchhhZErEnwR8klZmysBjFSLmOGjLhCYN7jWQRXjDyn7W-t55Q5uyOh14i7g&_hsmi=334976770&utm_content=334976770&utm_source=hs_email Study shows: Endometriosis tied to earlier deaths A growing body of evidence has shown that endometriosis (where tissue like that from the inside of the uterus grows on its outside) and uterine fibroids are linked to an increased risk of long-term chronic disease. A study published yesterday in The BMJ provides evidence for a more extreme potential link: Among more than 110,000 cisgender women, endometriosis was associated with a 31% higher risk of death before age 70, primarily driven by gynecological cancers. Uterine fibroids were also associated with higher risk of death specifically from gynecological cancers. Researchers analyzed data from nurses who participated in a survey study that ran from 1989- 2019. Participants were between the ages of 25 and 42 at the beginning of the study, and every couple years reported diagnoses of endometriosis or uterine fibroids. The authors noted that most participants were white, but believed that the large population and long-term results were still useful. https://www.statnews.com/2021/07/08/uterine-fibroids-overlooked-far-too-long/?utm_campaign=morning_rounds&utm_medium=email&_hsenc=p2ANqtz-8ribLrPQQFsHe6ayHdGfWto9cRpg7dUk2BQUKh8wVPZH03642l6BbKKR56DUbx6jJ26IyuQIBYWaDWvZEpPatIEZDDMw&_hsmi=334976770&utm_content=334976770&utm_source=hs_email

FDA approves updated drug labeling for fludarabine phosphate under Project Renewal

https://www.fda.gov/drugs/resources-information-approved-drugs/fda-approves-updated-drug-labeling-fludarabine-phosphate-under-project-renewal?utm_medium=email&utm_source=govdelivery

Webinar: Person-Centered Care Planning for People With Multiple Chronic Conditions

Webinar: Person-Centered Care Planning for People With Multiple Chronic Conditions: WhenDecember 3, 2024 at 1:00 p.m. ET Register for Dec. 3 Webinar on Care Planning for People with Multiple Chronic Conditions A webinar on Dec. 3 from 1 to 2 p.m. ET will feature preliminary findings from an AHRQ-funded project on approaches to providing person-centered care for people with multiple chronic conditions. Presenters from Oregon Health & Science University will identify persistent barriers and promising strategies for high quality care planning. The project was funded by the Patient-Centered Outcomes Research Trust Fund.

#25: Issuing a Report with the Assessment “Incomplete: Need additional imaging evaluation” in Follow-Up to an Initial Report with the Assessment “Incomplete: Need prior mammograms for comparison.”

https://www.fda.gov/radiation-emitting-products/regulations-mqsa/25-issuing-report-assessment-incomplete-need-additional-imaging-evaluation-follow-initial-report?utm_medium=email&utm_source=govdelivery

National Center on Substance Abuse and Child Welfare (NCSACW): Family Treatment Courts: An Evidence-Based Approach to Family-Centered Care — Webinar Tuesday, December 17, 1–3 p.m. ET

https://cffutures.zoom.us/webinar/register/WN_UZCgHK3pQUeUucdy1Incqw?utm_source=SAMHSA&utm_campaign=b806c9bc4b-EMAIL_CAMPAIGN_2024_11_14_02_47_COPY_01&utm_medium=email&utm_term=0_-b3ac68c241-167840245#/registration Are you curious about how family treatment courts (FTCs) improve outcomes for families involved with child welfare and affected by substance use disorders (SUDs)? Learn more about FTCs and discover how a family-centered approach helps achieve better outcomes. Presenters and panelists explore how FTCs implement a collaborative approach to resolve barriers in service access and engagement. Join this free event to discover the benefits of a family-centered approach and learn how to help families get the services they need. FTCs have compelling outcomes across various domains: Parents start SUD treatment earlier, stay longer, and experience better outcomes, including successful program completion and decreased substance use. Children placed in out-of-home care (OOHC) experience fewer days in care and increased reunification rates. Families gain increased access to comprehensive services and are less likely to experience recurrence of child maltreatment or OOHC reentry. Attendees will gain a greater understanding of: Foundational elements that make FTCs effective and help parents, children, and other family members obtain equal access to services. FTCs as an evidence-based approach to improve outcomes for families. The importance of a collaborative family-centered approach to FTCs’ success. Resources to implement an FTC.

We thought herpes was untreatable. Now, that might change Molly McElroy | Fred Hutchinson Cancer Research Center | June 19, 2024

https://geneticliteracyproject.org/2024/06/19/we-thought-herpes-was-untreatable-now-that-might-change/

Just in case: If humans near extinction, a 5-D ‘memory crystal’ might revive us Andrew Paul | Popular Science | November 19, 2024

https://geneticliteracyproject.org/2024/11/19/just-in-case-if-humans-near-extinction-a-5-d-memory-crystal-might-revive-us/?mc_cid=04d837b0ca&mc_eid=b73600b7ac

Why are women more likely to get long-Covid than men? Stephanie Soucheray | CIDRAP | November 19, 2024

https://geneticliteracyproject.org/2024/11/19/why-are-women-more-likely-to-get-long-covid-than-men/?mc_cid=04d837b0ca&mc_eid=b73600b7ac

Should women who use hormonal IUDs be concerned about developing cancer? Eldrid Borgan | Science Norway | November 19, 2024

https://geneticliteracyproject.org/2024/11/19/should-women-who-use-hormonal-iuds-be-concerned-about-developing-cancer-conflicting-data/?mc_cid=04d837b0ca&mc_eid=b73600b7ac

Pong addict? You should take a shot at playing a human created lifeless blob—that gets better over time Andrew Paul | Popular Science | November 20, 2024

https://geneticliteracyproject.org/2024/11/20/pong-addict-you-should-take-a-shot-at-playing-a-human-created-lifeless-blob-that-gets-better-over-time/?mc_cid=04d837b0ca&mc_eid=b73600b7ac

25% reduction: People genetically prone to breast cancer, diabetes and other diseases would benefit from gene screening Michael Peel | Financial Times | November 20, 2024

https://geneticliteracyproject.org/2024/11/20/25-reduction-people-genetically-prone-to-breast-cancer-diabetes-and-other-diseases-would-benefit-from-gene-screening/?mc_cid=04d837b0ca&mc_eid=b73600b7ac

In rare cases, coming down with COVID-19 could save your life Alice Park | Time | November 20, 2024

https://geneticliteracyproject.org/2024/11/20/in-rare-cases-coming-down-with-covid-19-could-save-your-life/?mc_cid=04d837b0ca&mc_eid=b73600b7ac

Patient-Focused Drug Development: Workshop to Discuss Methodologic and Other Challenges Related to Patient Experience Data December 13, 2024

https://www.fda.gov/drugs/news-events-human-drugs/patient-focused-drug-development-workshop-discuss-methodologic-and-other-challenges-related-patient?utm_medium=email&utm_source=govdelivery

Antibiotics: Know When and How to Use Them

Interim Guidance for Employers to Reduce Exposure to Novel Influenza A (Such as H5N1 Bird Flu) for People Working with or Exposed to Animals

https://www.cdc.gov/bird-flu/prevention/worker-protection-ppe.html?utm_medium=email&utm_source=govdelivery CDC Interim Guidance for Employers to Reduce Exposure to Novel Influenza A (Such as H5N1 Bird Flu) for People Working with or Exposed to Animals November 12, 2024 This updated interim guidance identifies work tasks that may pose an increased risk of worker exposure to novel influenza A viruses associated with disease in humans and provides recommended controls for each level. Specific recommendations for these work tasks may be updated as CDC learns more during this evolving situation. CDC Expands Guidance to Better Protect Farm Workers and Livestock Owners to Lower the Risk of Becoming infected with Bird Flu https://www.cdc.gov/bird-flu/spotlights/protect-farm-workers-bird-flu-11082024.html?CDC_AA_refVal=https%3A%2F%2Fwww.cdc.gov%2Fbird-flu%2Fspotlights%2Fprotect-farm-workers-bird-flu.html CDC Expands Guidance to Better Protect Farm Workers and Livestock Owners to Lower the Risk of Becoming Infected with Bird Flu November 8, 2024 This report highlights the need to offer testing and treatment to workers with exposure to sick animals, describes the need to improve and clarify guidance to farm workers and their employers about what personal protective equipment (PPE) to use, and how best to use it to protect themselves and prevent the spread of the virus. Investigation of Avian Influenza A (H5N1) Virus in Dairy Cattle https://www.fda.gov/food/alerts-advisories-safety-information/investigation-avian-influenza-h5n1-virus-dairy-cattle?utm_medium=email&utm_source=govdelivery#Status Status of the Milk Supply Last updated November 8, 2024 The process of pasteurization has helped ensure the health of the American public for more than 100 years. Pasteurization kills harmful bacteria and viruses by heating milk to a specific temperature over time. Even if HPAI virus is detected in raw milk, the current pasteurization process (HTST – High temperature, short time) will inactivate HPAI virus.

B-Cell Lymphoma | Advanced Cancer | Skin Cancer and Darker Skin, 11/20/2024

https://content.govdelivery.com/accounts/USNIHNCI/bulletins/3c2b6d4?reqfrom=share

BRAIN at 10: A View from the National Institute of Biomedical Imaging and Bioengineering

https://braininitiative.nih.gov/news-events/blog/brain-10-view-national-institute-biomedical-imaging-and-bioengineering

miércoles, 20 de noviembre de 2024

NIH-led scientific team defines elements of brain-based visual impairment in children Research needed to establish best diagnostic and management strategies for increasingly common condition.

https://www.nih.gov/news-events/news-releases/nih-led-scientific-team-defines-elements-brain-based-visual-impairment-children

New Resource for Researchers: NIH BioArt Source, a Free Science and Biomedical Art Resource Library

https://www.niaid.nih.gov/news-events/nih-bioart-source-free-biomedical-art-resource-library?utm_campaign=+63053822&utm_content=&utm_medium=email&utm_source=govdelivery&utm_term=

Mapping how cancers form and spread

https://www.nih.gov/news-events/nih-research-matters/mapping-how-cancers-form-spread

Early-life sugar intake affects chronic disease risk

https://www.nih.gov/news-events/nih-research-matters/early-life-sugar-intake-affects-chronic-disease-risk

Weight-loss surgery has lasting benefits in teens

https://www.nih.gov/news-events/nih-research-matters/weight-loss-surgery-has-lasting-benefits-teens

Weight Loss Surgery, Obesity Drugs Achieve Similar Results but Have Different Safety Profiles John Watson November 01, 2024

https://www.medscape.com/viewarticle/weight-loss-surgery-obesity-drugs-achieve-similar-results-2024a1000k0t?ecd=WNL_conf_gastro_ACG-SPON_241120_MSCPEDIT_etid7011913&uac=148436CN&impID=7011913

Promising New Data for Drugs Both Novel and Established in Several Common GI Conditions American College of Gastroenterology 2024 Annual Scientific Meeting Highlights: Part 1

https://www.medscape.com/viewarticle/promising-new-data-drugs-both-novel-and-established-several-2024a1000kdv?ecd=WNL_conf_gastro_ACG-SPON_241120_MSCPEDIT_etid7011913&uac=148436CN&impID=7011913

The New Penicillin? Pharmacotherapy for Obesity Nihar R. Desai, MD, MPH; Neda Rasouli, MD November 19, 2024

https://www.medscape.com/viewarticle/999845

Can Cardiac Coherence Improve Health? Dominique Baudon, MD, PhD | November 19, 2024

https://www.medscape.com/viewarticle/can-cardiac-coherence-improve-health-2024a1000kqy

Diagnosis and Management of Exocrine Pancreatic Insufficiency David C. Whitcomb, MD, PhD | November 19, 2024

https://www.medscape.com/viewarticle/diagnosis-and-management-exocrine-pancreatic-insufficiency-2024a1000knb

Ultrasonography-Guided Nerve Blocks Safe in Emergency Care Edited by Shrabasti Bhattacharya November 20, 2024

https://www.medscape.com/viewarticle/ultrasonography-guided-nerve-blocks-safe-emergency-care-2024a1000l5q

H pylori and FIT Co-Testing May Aid Gastric Cancer Screening Edited by Shrabasti Bhattacharya November 20, 2024

https://www.medscape.com/viewarticle/h-pylori-and-fit-co-testing-may-aid-gastric-cancer-screening-2024a1000l61

Two Brain Stim Methods Better Than One for Depression? Edited by Gargi Mukherjee November 20, 2024

https://www.medscape.com/viewarticle/two-brain-stim-methods-better-than-one-depression-2024a1000l5p

Most Older Adults With HIV Miss Bone Density Scans Heidi Splete November 20, 2024

https://www.medscape.com/viewarticle/most-older-adults-hiv-miss-bone-density-scans-2024a1000l5i

Telehealth Succeeds for Rapid ART in New HIV Patients Heidi Splete November 20, 2024

https://www.medscape.com/viewarticle/telehealth-succeeds-rapid-art-new-hiv-patients-2024a1000l5n

A Single-Question Screening Tool Could Identify Untreated Hearing Loss Lara Salahi November 20, 2024

https://www.medscape.com/viewarticle/single-question-screening-tool-could-identify-untreated-2024a1000l5s

Daytime Sleepiness May Flag Predementia Risk Edited by Anushree Chaphalkar November 20, 2024

https://www.medscape.com/viewarticle/daytime-sleepiness-may-flag-predementia-risk-2024a1000l5t

NHS to Expand Digital Diabetic Retinopathy Screening Peter Russell November 19, 2024

https://www.medscape.com/s/viewarticle/nhs-expand-digital-diabetic-retinopathy-screening-2024a1000l2q

Aliens, Ian McShane, and Heart Disease Risk F. Perry Wilson, MD, MSCE | November 19, 2024

https://www.medscape.com/viewarticle/aliens-ian-mcshane-and-heart-disease-risk-2024a1000kw8

New Pill Successfully Lowers Lp(a) Levels Brian Owens November 19, 2024 (Muvalaplin)

https://www.medscape.com/viewarticle/new-pill-successfully-lowers-lp-levels-2024a1000l13

martes, 19 de noviembre de 2024

FDA approves new treatment for uncomplicated urinary tract infections in adult women who have limited or no alternative oral antibiotic treatment options

https://www.fda.gov/drugs/news-events-human-drugs/fda-approves-new-treatment-uncomplicated-urinary-tract-infections-adult-women-who-have-limited-or-no?utm_medium=email&utm_source=govdelivery

Opioid alternatives In writing about new pain treatments that could benefit a family member, I was reminded of the real people behind every study and story.

https://www.drugdiscoverynews.com/opioid-alternatives-15665?utm_campaign=DDN_Newsletter_Dose&utm_medium=email&_hsenc=p2ANqtz-_wPp8mzXaf_4Loz6mgTfWJK99sygGufny7zc5JhQU1U86MyaogX_x_7kZJ_TNNvAambpr5TRmyTlEibsoaslGdm-HcYg&_hsmi=334446856&utm_content=334446856&utm_source=hs_email

The paradox of anti-inflammatory drugs New data suggest that an alternative mode of action may be at play for NSAIDs.

https://www.drugdiscoverynews.com/the-paradox-of-anti-inflammatory-drugs-15575?utm_campaign=DDN_Newsletter_Dose&utm_medium=email&_hsenc=p2ANqtz-8keeViEXxKO2mfa0ILIZnsN5fUrYver2FrqyqsCZIxlbBm7T98ydS0I_PMoL38Y-z3pRk4gTXFIbUtEb69H4a2hqkqhw&_hsmi=334446856&utm_content=334446856&utm_source=hs_email

A unique antidepressant may provide a new avenue to pain relief Researchers studied an antidepressant that may help treat neuropathic pain.

https://www.drugdiscoverynews.com/a-unique-antidepressant-may-provide-a-new-avenue-to-pain-relief-16137?utm_campaign=DDN_Newsletter_Dose&utm_medium=email&_hsenc=p2ANqtz-_feojWa5pOIlazS8ItELvIqLUKocqb_NDrwqVnlY-oi7ETn1ilNekrRa4JNy2oC3FMEv-FM2uHRxIZumSIlFpH2aS6qg&_hsmi=334446856&utm_content=334446856&utm_source=hs_email

Old drugs shed new light on a rare skin disease Drug repurposing trials for ichthyosis reveal complexity in the long-untreated disease.

https://www.drugdiscoverynews.com/old-drugs-shed-new-light-on-a-rare-skin-disease-16138

What is frozen shoulder? This painful condition strikes in middle age Experts give tips tips on relieving 'out-of-the-blue' pain and stiffness Angelica Stabile By Angelica Stabile Fox News Published November 13, 2024 8:00am EST

What is frozen shoulder? This painful condition strikes in middle age Experts give tips tips on relieving 'out-of-the-blue' pain and stiffness Angelica Stabile By Angelica Stabile Fox News Published November 13, 2024 8:00am EST https://www.foxnews.com/health/what-frozen-shoulder-painful-condition-tends-strike-middle-age

Bird flu leaves teen in critical condition after country's first reported case The teen had 'no underlying conditions' and deteriorated quickly, according to BC authorities Angelica Stabile By Angelica Stabile , Melissa Rudy Fox News Published November 13, 2024 12:03pm EST

Bird flu leaves teen in critical condition after country's first reported case The teen had 'no underlying conditions' and deteriorated quickly, according to BC authorities Angelica Stabile By Angelica Stabile , Melissa Rudy Fox News Published November 13, 2024 12:03pm EST https://www.foxnews.com/health/bird-flu-leaves-teen-critical-condition-country-first-reported-case

Autism risk could rise with air pollution, new study suggests One pollutant is contained in car exhaust, found new study, which had some limitations Melissa Rudy By Melissa Rudy Fox News Published November 13, 2024 2:34pm EST

Autism risk could rise with air pollution, new study suggests One pollutant is contained in car exhaust, found new study, which had some limitations Melissa Rudy By Melissa Rudy Fox News Published November 13, 2024 2:34pm EST https://www.foxnews.com/health/autism-risk-could-rise-air-pollution-study-suggests

Legionnaires’ disease outbreak linked to cruise ship hot tubs, CDC says The infection can lead to severe pneumonia in older and immunocompromised people By Amy McGorry Fox News Published November 14, 2024 8:00am EST

Legionnaires’ disease outbreak linked to cruise ship hot tubs, CDC says The infection can lead to severe pneumonia in older and immunocompromised people By Amy McGorry Fox News Published November 14, 2024 8:00am EST https://www.foxnews.com/health/legionnaires-disease-outbreak-linked-cruise-ship-hot-tubs-cdc-says