jueves, 16 de enero de 2025
Dear friends, the blog will not be updated for 72 hours... please pray for me... thank you very much...
Dear friends, the blog will not be updated for 72 hours... please pray for me... thank you very much...
Liebe Freunde, der Blog wird 72 Stunden lang nicht aktualisiert … bitte betet für mich … vielen Dank …
Chers amis, le blog ne sera pas mis à jour pendant 72 heures... s'il vous plaît priez pour moi... merci beaucoup...
miércoles, 15 de enero de 2025
Robots and AI Are Working Together to Bring You Better Medicines, Shampoo and More January 15, 2025
https://www.nist.gov/blogs/taking-measure/robots-and-ai-are-working-together-bring-you-better-medicines-shampoo-and-more
For 72 hours the blog will not be updated... please pray for me, thank you...
Conect4children Multi-Stakeholder Meeting
https://conect4children.org/
Conect4children Multi-Stakeholder Meeting
Conect4children (c4c) is inviting stakeholders to its final International Multi-Stakeholder Meeting on paediatric Chronic Kidney Disease (CKD), taking place in Heidelberg and online from 28-29 April. This hybrid event will unite patients, clinicians, academics, industry leaders, and regulators to address gaps in paediatric CKD treatment and shape strategies for future clinical trials and therapies.
https://conect4children.org/wp-content/uploads/2024/12/c4c_MSM-KCD_Advert-EOI_to-circulate-1.pdf
THE DIGITAL ACADEMY FOR MEDICINES REPURPOSING
https://academy.remedi4all.org/
On 29 January, the REMEDi4ALL Digital Academy will host a webinar to launch its innovative online platform for training in drug repurposing, offering accessible resources and insights for every stage of the process. The webinar will feature speakers from REMEDi4ALL partners, including Beacon for Rare Disease and EURORDIS.
Later in the year, join the International Drug Repurposing Conference (iDR25) in Amsterdam on 7–8 May, where global experts will discuss cutting-edge innovations, patient-centric approaches, and policy advancements in repurposing medicines. Early-bird tickets for iDR25 are available now.
https://remedi4all.org/2025-international-drug-repurposing-conference/
New Medicines R&D course
New Medicines R&D course
The EURORDIS Open Academy has launched an updated version of the Medicines Research and Development course – now more focused, interactive, and engaging. This version offers a comprehensive resource tailored for rare disease patient advocates. Access the course today!
https://openacademy.eurordis.org/courses/medical-research-development/
Podcast: Rare on Air
https://www.eurordis.org/rare-on-air/
In the latest episode of Rare on Air, host Julien Poulain sits down with Julián Isla, a rare disease advocate, AI expert, and father to a son living with Dravet syndrome. Julián shares his journey through his son's misdiagnosis and challenges, and how this led him to co-found Foundation 29, which is using artificial intelligence (AI) to transform rare disease diagnostics and care. Upon discussing how AI is improving healthcare, Julián addresses the regulatory, cultural, and medical barriers hindering its full potential for families impacted by rare diseases. Listen now!
https://www.foundation29.org/#home
28 February is Rare Disease Day
https://www.rarediseaseday.org/
With just 44 days to go until Rare Disease Day on 28 February 2025, don’t miss the latest episodes of our Rare Disease Day Stories bonus podcast series, bringing powerful personal experiences to light. In our two most recent episodes, listen to the stories of Emma and Nellie from the UK and of Fatimah from Nigeria. Also, do not forget to get involved in the campaign by exploring and deploying Rare Disease Day's many downloadable resources!
https://www.rarediseaseday.org/downloads/
https://www.eurordis.org/rare-on-air/
Better Prevention: About ERDERA - The European Rare Disease Research Alliance (ERDERA)
https://erdera.org/
The European Rare Diseases Research Alliance (ERDERA) has launched its 2025 Joint Transnational Call, inviting research teams to collaborate on pre-clinical therapy studies for rare diseases using small molecules and biologicals. With a pre-proposal deadline of 13 February, this funding opportunity aims to accelerate scientific innovation and international collaboration.
https://erdera.org/funding/
martes, 14 de enero de 2025
“Patient-centricity” is more than a buzzword — it’s a call to action
Self-reported contraceptive method use at conception among patients presenting for abortion in England: a cross-sectional analysis comparing 2018 and 2023
https://srh.bmj.com/content/early/2025/01/01/bmjsrh-2024-202573?utm_campaign=morning_rounds&utm_medium=email&_hsenc=p2ANqtz-8RUJBEfsEHrWAiVQATdWd_iHz27aig49ZxvChKmh8O_QUgfS3iHwJclEcgXOY-N4UhywZ1tYPSQusrwXZlAkUsxQ5wwg&_hsmi=342354081&utm_content=342354081&utm_source=hs_email
Study shows a shift to ‘natural’ birth control or none at all
People in the U.K. are using effective hormonal birth control methods less than they were five years ago, according to a study published yesterday in BMJ Sexual and Reproductive Health. At the same time, more people are using “natural” methods like tracking one’s period and body temperature to make fertility predictions. There’s also been a significant increase in the number of people not using any birth control at all, per the study.
To assess recent trends, researchers compared the self-reported birth control practices of around 33,400 people who sought an abortion in early 2018 with 55,000 people who did in early 2023. Just 0.4% people in 2018 used “natural” birth control, while 2.5% did in 2023. Hormonal methods decreased from 18.8% to 11.3%, while those using no birth control increased from 55.8% to almost 70%.
The changes are part of a larger trend of apparent hesitancy to take the pill. About half of reproductive-age females in the U.K. took the pill in 2010, but by 2018 it was down to 14%. The study authors point to both personal preference and a lack of access as potential motivators, but say more research is needed.
Raw milk can be safe — but it depends on something in short supply Namely, trust between health officials, consumers, and producers
https://www.statnews.com/2025/01/14/raw-milk-safety-h5n1-avian-flu-state-regulation/?utm_campaign=morning_rounds&utm_medium=email&_hsenc=p2ANqtz-_KnnU5acs7YfqG3sPoafKmNkG2yJYIj1iaQzOp3QPWGZWL8ZxKz_wXEihwauNF55j7SnI3_8PbeuuGtC6T_aponcLpFw&_hsmi=342354081&utm_content=342354081&utm_source=hs_email
Scientists have always cautioned against drinking raw milk. But as bird flu began circulating in dairy cows across the country last spring, the warnings became more vehement. By the fall, the virus was found in commercially available raw milk. The exact health risks of drinking this milk are unknown, but recent research supports the fear that it may be dangerous.
I was surprised, then, to read a First Opinion essay published today by audio documentarian Bianca Garcia, who argues that raw milk as a product isn’t inherently dangerous with the appropriate management. Garcia has been reporting on raw milk for months, and points to South Carolina as an example of a state with vigorous regulations around testing and sanitation for the raw milk market.
It’s a provocative idea, but Garcia comes with evidence for a sort of harm reduction approach.
https://www.statnews.com/2024/11/24/bird-flu-h5n1-raw-milk-llc-california-virus-testing/?utm_campaign=morning_rounds&utm_medium=email&_hsenc=p2ANqtz-9FbDsF5yru9RNu5MGH2Bi2cJOhonmtpBaWqALTO_SaUH1R3YmPWF_EFyJC8Pnd7XCyHqsXqN4wcewpTCUaJxtDyz_AsQ&_hsmi=342354081&utm_content=342354081&utm_source=hs_email
lunes, 13 de enero de 2025
CTCL: Shortening the Diagnostic Journey and Starting Treatment Early By: CheckRare Staff|
https://checkrare.com/ctcl-shortening-the-diagnostic-journey-and-starting-treatment-early/
CTCL: The Role of Dermatologists in Diagnosing and Caring for Patients
By: CheckRare Staff|
https://checkrare.com/ctcl-the-role-of-dermatologists-in-diagnosing-and-caring-for-patients/
Drug Trials Snapshots: EXXUA (gepirone)
EXXUA is an antidepressant drug used for the treatment of major depressive disorder (MDD) in adults.
https://www.fda.gov/drugs/drug-approvals-and-databases/drug-trials-snapshots-exxua
domingo, 12 de enero de 2025
Seeing eye to eye: building a cost-effective tool to visualize cancer
Seeing eye to eye: building a cost-effective tool to visualize cancer: Seeing eye to eye: building a cost-effective tool to visualize cancer
Science Highlights
January 10, 2025
Heart emergency visits plunged during Covid, study shows Israeli public-health study shows that multiple and complex factors can influence people's health behaviors during crises such as pandemics.
Heart emergency visits plunged during Covid, study shows
Israeli public-health study shows that multiple and complex factors can influence people's health behaviors during crises such as pandemics.
https://www.israel21c.org/heart-emergency-visits-plunged-during-covid-study-shows/
Scientists discover way to make pig organs compatible to humans
Scientists discover way to make pig organs compatible to humans
Surgeons would be able to order hybrid organs – a pig organ with a human lining of blood vessels-that could help solve the acute shortage of organs for transplant.
https://www.israel21c.org/scientists-discover-way-to-make-pig-organs-compatible-to-humans/
JUST 30 MINUTES OF EXERCISE CAN HELP PREVENT DIABETES
Just 30 Minutes of Exercise Can Help Prevent Diabetes
By Ivanhoe Broadcast News on January 9, 2025
https://www.ivanhoe.com/family-health/just-30-minutes-of-exercise-can-help-prevent-diabetes/
HEALTHY PREGNANCY, HEALTHY BABY: EATING YOUR WAY TO SUCCESS
Healthy Pregnancy, Healthy Baby: Eating Your Way to Success
By Ivanhoe Broadcast News on January 10, 2025
https://www.ivanhoe.com/family-health/healthy-pregnancy-healthy-baby-eating-your-way-to-success/
NEW YEAR, NEW JOB: CAREER TRENDS FOR 2025
New Year, New Job: Career Trends For 2025
By Ivanhoe Broadcast News on January 14, 2025
https://www.ivanhoe.com/?p=34868&preview=1&_ppp=b3c3976eec
LOVE’EM OR LEAVE’EM: DIVORCES AND ONLINE DATING
Love ‘Em Or Leave ‘Em: Divorces And Online Dating
By Ivanhoe Broadcast News on January 15, 2025
https://www.ivanhoe.com/?p=34870&preview=1&_ppp=2334d3c43a
GOD HELP US! FAITH AND HEART HEALTH
God Help Us! Faith And Heart Health
By Ivanhoe Broadcast News on January 16, 2025
https://www.ivanhoe.com/?p=34872&preview=1&_ppp=7996890cd7
HOME ALONE: HOW YOUNG IS TOO YOUNG FOR KIDS
Home Alone: How Young Is Too Young For Kids?
By Ivanhoe Broadcast News on January 17, 2025
https://www.ivanhoe.com/?p=34874&preview=1&_ppp=fca2677d5b
sábado, 11 de enero de 2025
CLINICAL PERSPECTIVES: Recent Data Regarding Treatment for Hepatorenal Syndrome By: Madaline Spencer| Published on: Dec 27, 2024 +++++
Recent Data Regarding Treatment for Hepatorenal Syndrome
By: Madaline Spencer| Published on: Dec 27, 2024
https://checkrare.com/recent-data-regarding-treatment-for-hepatorenal-syndrome/
NDA Submission of Paltusotine for Acromegaly
Alan Krasner, MD, Chief Medical Officer of Crinetics Pharmaceuticals, discusses the new drug application (NDA) submission of paltusotine for treating acromegaly.
NDA Submission of Paltusotine for Acromegaly
By: Madaline Spencer| Published on: Dec 23, 2024
https://checkrare.com/nda-submission-of-paltusotine-for-acromegaly/
Symptom Burden of Primary Biliary Cholangitis
Carol Roberts, President, The PBCers Organization, discusses the symptom burden of primary biliary cholangitis (PBC).
Symptom Burden of Primary Biliary Cholangitis
By: Madaline Spencer| Published on: Dec 20, 2024
https://checkrare.com/symptom-burden-of-primary-biliary-cholangitis/
African American with Huntington’s Disease Explains Her Diagnostic Journey
Tanita Allen, a patient advocate with Huntington disease, discusses her diagnostic journey and advocacy work.
African American with Huntington’s Disease Explains Her Diagnostic Journey
By: Madaline Spencer| Published on: Dec 19, 2024
https://checkrare.com/african-american-with-huntingtons-disease-explains-her-diagnostic-journey/
Tardive Dyskinesia Strongly Impacts Quality of Life: Data from the IMPACT-TD Registry
Rakesh Jain, MD, MPH, Clinical Professor of Psychiatry, discusses tardive dyskinesia (TD) data from the IMPACT-TD Registry study.
Tardive Dyskinesia Strongly Impacts Quality of Life: Data from the IMPACT-TD Registry
By: Madaline Spencer| Published on: Dec 18, 2024
https://checkrare.com/tardive-dyskinesia-strongly-impacts-quality-of-life-data-from-the-impact-td-registry/
CLINICAL PERSPECTIVES: Recent Advances in Fabry Disease Clinical Research +++++
CLINICAL PERSPECTIVES
Recent Advances in Fabry Disease Clinical Research
David Warnock, MD, Professor of Medicine (Emeritus), University of Alabama at Birmingham, discusses recent advances in Fabry disease clinical research.
Recent Advances in Fabry Disease Clinical Research
By: Madaline Spencer| Published on: Jan 8, 2025
https://checkrare.com/recent-advances-in-fabry-disease-clinical-research/
GRIDS Symposium Celebrates its 10th Anniversary
Ozlem Goker-Alpan, MD, Founder and Chief Medical Officer of the Lysosomal & Rare Disorders Research & Treatment Center (LDRTC), discusses her work in lysosomal storage diseases and the GRIDS conference.
GRIDS Symposium Celebrates its 10th Anniversary
By: Madaline Spencer| Published on: Jan 7, 2025
https://checkrare.com/grids-symposium-celebrates-its-10th-anniversary/
New Data on Investigational Dravet Syndrome Treatment
Joseph E. Sullivan, MD, Professor of Neurology & Pediatrics at University of California San Francisco and Director of Benioff Children’s Hospital Pediatric Epilepsy Center of Excellence, discusses zovrevunersen for the treatment of patients with Dravet syndrome.
New Data on Investigational Dravet Syndrome Treatment
By: Madaline Spencer| Published on: Jan 6, 2025
https://checkrare.com/new-data-on-investigational-dravet-syndrome-treatment/
Citizen Health: AI-Powered Platform for Rare Conditions
Farid Vij and Nasha Fitter, co-founders of Citizen Health, discuss how their organization helps rare disease patients.
Citizen Health: AI-Powered Platform for Rare Conditions
By: Madaline Spencer| Published on: Jan 3, 2025
https://checkrare.com/citizen-health-ai-powered-platform-for-rare-conditions/
PFIC and Alagille Syndrome Studies
James Squires, MD, University of Pittsburgh, discusses recent data regarding Bylvay (odevixibat) in patients with progressive familial intrahepatic cholestasis (PFIC) and Alagille syndrome.
PFIC and Alagille Syndrome Studies
By: Madaline Spencer| Published on: Dec 30, 2024
https://checkrare.com/pfic-and-alagille-syndrome-studies/
viernes, 10 de enero de 2025
Extreme weather is threatening global food supplies. What can be done? Nature Conservancy | January 8, 2025 +++
https://geneticliteracyproject.org/2025/01/08/extreme-weather-is-threatening-global-food-supplies-what-can-be-done/?mc_cid=3b74bc79a9&mc_eid=b73600b7ac
With the commercialization of a disease-resistant pig likely in 2025, gene editing poised to usher in a new era of biotech plants and animals
Michael Le Page | New Scientist | January 7, 2025
https://geneticliteracyproject.org/2025/01/07/with-the-commercialization-of-a-disease-resistant-pig-likely-in-2025-gene-editing-poised-to-usher-in-a-new-era-of-biotech-plants-and-animals/?mc_cid=3b74bc79a9&mc_eid=b73600b7ac
Video: Feed the Planet: Building a cooler relationship between an Earth for 8 billion
Amelia Finaret, Andy Revkin, George Steinmetz, William Masters | YouTube | January 7, 2025
https://geneticliteracyproject.org/2025/01/07/video-feed-the-planet-building-a-cooler-relationship-between-an-earth-for-8-billion/?mc_cid=3b74bc79a9&mc_eid=b73600b7ac
jueves, 9 de enero de 2025
miércoles, 8 de enero de 2025
Another reason to get more sleep and this one might surprise you Sleep findings could 'revolutionize' education, rehab and cognitive training, say researchers By Maureen Mackey Fox News Published January 6, 2025 9:49am EST
Another reason to get more sleep and this one might surprise you
Sleep findings could 'revolutionize' education, rehab and cognitive training, say researchers
By Maureen Mackey Fox News
Published January 6, 2025 9:49am EST
https://www.foxnews.com/health/reason-get-more-sleep-might-surprise-you
AI detects ovarian cancer better than human experts in new study The tool showed promising accuracy in reading scans, but limitations remain Melissa Rudy By Melissa Rudy Fox News Published January 6, 2025 4:30am EST
AI detects ovarian cancer better than human experts in new study
The tool showed promising accuracy in reading scans, but limitations remain
Melissa Rudy By Melissa Rudy Fox News
Published January 6, 2025 4:30am EST
https://www.foxnews.com/health/ai-detects-ovarian-cancer-better-human-experts-new-study
Michael J. Fox honored with Presidential Medal of Freedom for Parkinson’s research efforts Fox, who was diagnosed with Parkinson's in 1991, launched the Michael J. Fox Foundation for Parkinson’s Research in 2000 Angelica Stabile By Angelica Stabile Fox News Published January 6, 2025 2:20pm EST
Michael J. Fox honored with Presidential Medal of Freedom for Parkinson’s research efforts
Fox, who was diagnosed with Parkinson's in 1991, launched the Michael J. Fox Foundation for Parkinson’s Research in 2000
Angelica Stabile By Angelica Stabile Fox News
Published January 6, 2025 2:20pm EST
https://www.foxnews.com/health/michael-j-fox-honored-presidential-medal-freedom-parkinsons-research-efforts
Louisiana reports first bird flu-related human death in US The unidentified patient was over 65 and reportedly had underlying medical conditions Louis Casiano By Louis Casiano , Melissa Rudy Fox News Published January 6, 2025 3:47pm EST
Louisiana reports first bird flu-related human death in US
The unidentified patient was over 65 and reportedly had underlying medical conditions
Louis Casiano By Louis Casiano , Melissa Rudy Fox News
Published January 6, 2025 3:47pm EST
https://www.foxnews.com/health/louisiana-reports-first-bird-flu-related-human-death-us
CDC monitoring possible spike of HMPV cases in China CDC says HMPV is increasing in US but is 'not currently a cause for concern' Christina Shaw By Christina Shaw Fox News Published January 7, 2025 2:35am EST
CDC monitoring possible spike of HMPV cases in China
CDC says HMPV is increasing in US but is 'not currently a cause for concern'
Christina Shaw By Christina Shaw Fox News
Published January 7, 2025 2:35am EST
https://www.foxnews.com/health/cdc-monitoring-possible-spike-hmpv-cases-china
7 signs you might have ADHD and what steps to take 15.5 million adults in the US are currently living with attention-deficit/hyperactivity disorder Melissa Rudy By Melissa Rudy Fox News Published January 7, 2025 4:30am EST
7 signs you might have ADHD and what steps to take
15.5 million adults in the US are currently living with attention-deficit/hyperactivity disorder
Melissa Rudy By Melissa Rudy Fox News
Published January 7, 2025 4:30am EST
https://www.foxnews.com/health/7-signs-you-might-have-adhd-what-steps-take
'I'm a neurosurgeon – this is what I eat for a brain-healthy breakfast' Dr. Paul Saphier, M.D., offers breakfast ideas to optimize cognitive health Angelica Stabile By Angelica Stabile Fox News Published January 7, 2025 12:46pm EST
'I'm a neurosurgeon – this is what I eat for a brain-healthy breakfast'
Dr. Paul Saphier, M.D., offers breakfast ideas to optimize cognitive health
Angelica Stabile By Angelica Stabile Fox News
Published January 7, 2025 12:46pm EST
https://www.foxnews.com/health/im-neurosurgeon-what-eat-brain-healthy-breakfast
Can eggs spread bird flu? What you must know A registered dietitian shares cautions about eating soft-boiled or 'runny' eggs while avian flu persists Angelica Stabile By Angelica Stabile Fox News Published January 7, 2025 3:30pm EST | Updated January 7, 2025 3:45pm EST
Can eggs spread bird flu? What you must know
A registered dietitian shares cautions about eating soft-boiled or 'runny' eggs while avian flu persists
Angelica Stabile By Angelica Stabile Fox News
Published January 7, 2025 3:30pm EST | Updated January 7, 2025 3:45pm EST
https://www.foxnews.com/health/can-eggs-spread-bird-flu-what-you-must-know
Virus outbreak in China sparks pandemic concerns: What to know about HMPV Symptoms are mild for most, but certain groups are at higher risk, experts say Melissa Rudy By Melissa Rudy Fox News Published January 8, 2025 4:30am EST
Virus outbreak in China sparks pandemic concerns: What to know about HMPV
Symptoms are mild for most, but certain groups are at higher risk, experts say
Melissa Rudy By Melissa Rudy Fox News
Published January 8, 2025 4:30am EST
https://www.foxnews.com/health/virus-outbreak-china-sparks-pandemic-concerns-what-know-hmpv
Screening and Prevention: ++++ Oral Cavity, Oropharyngeal, Hypopharyngeal, and Laryngeal Cancers Prevention (PDQ®)–Health Professional Version // Prostate Cancer Prevention (PDQ®)–Health Professional Version // Stomach (Gastric) Cancer Prevention (PDQ®)–Health Professional Version // Testicular Cancer Screening (PDQ®)–Health Professional Version
Screening and Prevention
Oral Cavity, Oropharyngeal, Hypopharyngeal, and Laryngeal Cancers Prevention
Oral Cavity, Oropharyngeal, Hypopharyngeal, and Laryngeal Cancers Prevention (PDQ®)–Health Professional Version
https://www.cancer.gov/types/head-and-neck/hp/oral-prevention-pdq?cid=eb_govdel#top
We updated information on
Incidence and Mortality
Prostate Cancer Prevention
Prostate Cancer Prevention (PDQ®)–Health Professional Version
https://www.cancer.gov/types/prostate/hp/prostate-prevention-pdq?cid=eb_govdel#top
We updated information on
Risk Factors for Prostate Cancer Development
Stomach (Gastric) Cancer Prevention
Stomach (Gastric) Cancer Prevention (PDQ®)–Health Professional Version
https://www.cancer.gov/types/stomach/hp/stomach-prevention-pdq?cid=eb_govdel#top
We updated information on
Incidence and Mortality
Testicular Cancer Screening
Testicular Cancer Screening (PDQ®)–Health Professional Version
https://www.cancer.gov/types/testicular/hp/testicular-screening-pdq?cid=eb_govdel#top
We updated information on
Incidence and Mortality
Cancer Genetics: +++ Cancer Genetics Risk Assessment and Counseling (PDQ®)–Health Professional Version // Genetics of Breast and Gynecologic Cancers (PDQ®)–Health Professional Version // Genetics of Colorectal Cancer (PDQ®)–Health Professional Version
Cancer Genetics
Cancer Genetics Risk Assessment and Counseling
Cancer Genetics Risk Assessment and Counseling (PDQ®)–Health Professional Version
https://www.cancer.gov/publications/pdq/information-summaries/genetics/risk-assessment-hp-pdq?cid=eb_govdel#top
Genetics of Breast and Gynecologic Cancers
Genetics of Breast and Gynecologic Cancers (PDQ®)–Health Professional Version
https://www.cancer.gov/types/breast/hp/breast-ovarian-genetics-pdq?cid=eb_govdel#top
Genetics of Colorectal Cancer
Genetics of Colorectal Cancer (PDQ®)–Health Professional Version
https://www.cancer.gov/types/colorectal/hp/colorectal-genetics-pdq?cid=eb_govdel#top
We updated information on
Major Genetic Syndromes
6 Tips: How Herbs Can Interact With Medicines
https://www.nccih.nih.gov/health/tips/tips-how-herbs-can-interact-with-medicines?nav=govd
It’s common for people to take both herbal supplements and prescription or over-the-counter drugs. But did you know that some herbs and supplements may interact in harmful ways? For many herbs and supplements, there’s currently little information on possible interactions, and more research is needed. But we do know that certain herbs have a high risk of interacting with medicines:
St. John’s wort interacts with many types of drugs. In most instances, it speeds up the processes that change the drug into inactive substances, leading to a decrease in drug levels in your body. St. John’s wort can also interact with certain antidepressants and other drugs in a different way that increases the risk of serious serotonin-related side effects.
Other herbal products that may interact with drugs include concentrated green tea supplements, goldenseal, and Asian ginseng.
It’s important to tell your health care providers about all medicines and supplements you take so they can help you avoid interactions.
Drug Trials Snapshots: ORLYNVAH (sulopenem etzadroxil and probenecid)
ORLYNVAH is a combination of sulopenem etzadroxil (a penem antibiotic drug) and probenecid (a kidney transport blocking drug) that is indicated for the treatment of uncomplicated urinary tract infections (uUTI) caused by the bacteria Escherichia coli, Klebsiella pneumoniae, or Proteus mirabilis in adult female patients who have limited or no alternative oral antibiotic treatment options.
https://www.fda.gov/drugs/drug-approvals-and-databases/drug-trials-snapshots-orlynvah
martes, 7 de enero de 2025
Docs Worry Not Enough Known About GLP-1s and Teens Joanna Broder January 02, 2025 +++++
Latest Stories
Are GLP-1s Safe for Teens?
Docs Worry Not Enough Known About GLP-1s and Teens
Joanna Broder
https://www.medscape.com/viewarticle/docs-worry-not-enough-known-about-glp-1s-and-teens-2025a100001w?ecd=mkm_ret_250104_mscpmrk_MOB_e11_etid7140038&uac=148436CN&impID=7140038
January 02, 2025
GLP-1s: When Not to Prescribe
GLP-1 RAs: When Not to Prescribe
Tamaan K. Osbourne-Roberts, MD, MBA
https://www.medscape.com/viewarticle/glp-1-ras-when-not-prescribe-2024a1000nd8?ecd=mkm_ret_250104_mscpmrk_MOB_e11_etid7140038&uac=148436CN&impID=7140038
Exposure to Dioxins May Increase Obesity Risk
Exposure to Dioxins May Increase Obesity Risk
Edited by Vinod Rane
https://www.medscape.com/viewarticle/exposure-dioxins-may-increase-obesity-risk-2025a100000q?ecd=mkm_ret_250104_mscpmrk_MOB_e11_etid7140038&uac=148436CN&impID=7140038
January 02, 2025
Exercising Longer May Boost Weight Loss, Meta-Analysis Shows
Exercising Longer May Boost Weight Loss, Meta-Analysis Shows
Edited by Shreyasi Asthana
https://www.medscape.com/viewarticle/exercising-longer-may-boost-weight-loss-meta-analysis-shows-2025a100000p?ecd=mkm_ret_250104_mscpmrk_MOB_e11_etid7140038&uac=148436CN&impID=7140038
January 02, 2025
GLP-1s May Cut Risk for Late-Onset Epilepsy
GLP-1s May Cut Risk for Late-Onset Epilepsy
Pauline Anderson
https://www.medscape.com/viewarticle/glp-1s-may-cut-risk-late-onset-epilepsy-2024a1000nbe?ecd=mkm_ret_250104_mscpmrk_MOB_e11_etid7140038&uac=148436CN&impID=7140038
lunes, 6 de enero de 2025
Long QT Syndrome +++
https://emedicine.medscape.com/article/157826-overview?ecd=mkm_ret_250104_mscpmrk_cardio_ecg_etid7138536&uac=148436CN&impID=7138536
Electrocardiography
https://emedicine.medscape.com/article/1894014-overview?ecd=mkm_ret_250104_mscpmrk_cardio_ecg_etid7138536&uac=148436CN&impID=7138536
Normal Electrocardiography (ECG) Intervals
https://emedicine.medscape.com/article/2172196-overview?ecd=mkm_ret_250104_mscpmrk_cardio_ecg_etid7138536&uac=148436CN&impID=7138536
Dizziness, Vertigo, and Imbalance ++
AI Catches Missing MRI Lesions Jim Kling December 23, 2024 +++
TECH TRANSFORMS CARE
AI Catches Missing MRI Lesions
AI Catches Missing MRI Lesions
Jim Kling
https://www.medscape.com/viewarticle/ai-catches-missing-mri-lesions-2024a1000p16?ecd=mkm_ret_250104_mscpmrk_neuro_epilepsy_etid7139878&uac=148436CN&impID=7139878
December 23, 2024
Smart Mattress to Reduce SUDEP?
Smart Mattress to Reduce SUDEP?
Pauline Anderson
https://www.medscape.com/viewarticle/smart-mattress-reduce-sudep-2024a1000mp7?ecd=mkm_ret_250104_mscpmrk_neuro_epilepsy_etid7139878&uac=148436CN&impID=7139878
Early Promise in Detecting Infantile Spasms
AI Shows Early Promise in Detecting Infantile Spasms
Jim Kling
https://www.medscape.com/viewarticle/ai-shows-early-promise-detecting-infantile-spasms-2024a1000muh?ecd=mkm_ret_250104_mscpmrk_neuro_epilepsy_etid7139878&uac=148436CN&impID=7139878
Sleep Apnea Linked to Heightened Mortality in Epilepsy Jim Kling +++
MANAGING SEIZURES
Sleep Apnea Linked to Mortality in Epilepsy
Sleep Apnea Linked to Heightened Mortality in Epilepsy
Jim Kling
https://www.medscape.com/viewarticle/sleep-apnea-linked-heightened-mortality-epilepsy-2024a1000mp9?ecd=mkm_ret_250104_mscpmrk_neuro_epilepsy_etid7139878&uac=148436CN&impID=7139878
New Guidelines Needed for Seizure Clusters?
Survey Reveals Wide Practice Range for Seizure Clusters
Jim Kling
https://www.medscape.com/viewarticle/survey-reveals-wide-practice-range-seizure-clusters-2024a1000nar?ecd=mkm_ret_250104_mscpmrk_neuro_epilepsy_etid7139878&uac=148436CN&impID=7139878
‘Urgent Need’ to Examine Anti-Seizure Drug Pricing
‘Urgent Need’ to Examine Anti-Seizure Medication Pricing
Pauline Anderson
https://www.medscape.com/viewarticle/urgent-need-examine-anti-seizure-medication-pricing-2024a1000n3y?ecd=mkm_ret_250104_mscpmrk_neuro_epilepsy_etid7139878&uac=148436CN&impID=7139878
Women Largely Unaware of Anti-Seizure Med Risks, More Education Needed Pauline Anderson +++
RISK FACTORS
Women Largely Unaware of Anti-Seizure Med Risks
Women Largely Unaware of Anti-Seizure Med Risks, More Education Needed
Pauline Anderson
https://www.medscape.com/viewarticle/women-largely-unaware-anti-seizure-med-risks-more-education-2024a1000mvj?ecd=mkm_ret_250104_mscpmrk_neuro_epilepsy_etid7139878&uac=148436CN&impID=7139878
GLP-1s May Cut Risk for Late-Onset Epilepsy
GLP-1s May Cut Risk for Late-Onset Epilepsy
Pauline Anderson
https://www.medscape.com/viewarticle/glp-1s-may-cut-risk-late-onset-epilepsy-2024a1000nbe?ecd=mkm_ret_250104_mscpmrk_neuro_epilepsy_etid7139878&uac=148436CN&impID=7139878
Cut Epilepsy Risk in Patients with Hypertension
ARBs Cut Epilepsy Risk in Patients with Hypertension
Pauline Anderson
https://www.medscape.com/viewarticle/arbs-cut-epilepsy-risk-patients-hypertension-2024a1000n2b?ecd=mkm_ret_250104_mscpmrk_neuro_epilepsy_etid7139878&uac=148436CN&impID=7139878
domingo, 5 de enero de 2025
sábado, 4 de enero de 2025
Tumor-intrinsic kinome landscape of pancreatic cancer reveals new therapeutic approaches. +++++++++
https://read.qxmd.com/read/39632628/tumor-intrinsic-kinome-landscape-of-pancreatic-cancer-reveals-new-therapeutic-approaches?uac=148436CN&ecd=wnl_readmost_250103&sso=true&redirected=slug
Tumor-intrinsic kinome landscape of pancreatic cancer reveals new therapeutic approaches.
Effective therapies for pancreatic ductal adenocarcinoma (PDAC) have been largely elusive. Here, we perform Multiplexed kinase Inhibitor Bead Mass Spectrometry ..
Dec 5, 2024: Cancer Discovery
Head-to-head comparison of palbociclib and ribociclib in first-line treatment of HR-positive/HER2-negative metastatic breast cancer with real-world data from the OPAL registry.
Marc Thill, Mark-Oliver Zahn, Anja Welt, Arnd Nusch, Matthias Zaiss, Kathrin Engelken, Gabriele Kaltenecker, Kai Ringwald, Katja Gratzke, Stephanie Dille, Lisa Kruggel, Martina Jänicke, Holger Schulz, Volker Hagen, Roland Fricker, Elmar Stickeler, Nadia Harbeck, Achim Wöckel, Thomas Decker
International Journal of Cancer. Journal International du Cancer 2024 December 20
https://read.qxmd.com/read/39707595/head-to-head-comparison-of-palbociclib-and-ribociclib-in-first-line-treatment-of-hr-positive-her2-negative-metastatic-breast-cancer-with-real-world-data-from-the-opal-registry?uac=148436CN&ecd=wnl_readmost_250103&sso=true&redirected=slug
Breaking the mold: Unconventional T cells in cancer therapy.
Yan-Ruide Li, Kuangyi Zhou, Yichen Zhu, Tyler Halladay, Lili Yang
Cancer Cell 2024 December 6
https://read.qxmd.com/read/39672171/breaking-the-mold-unconventional-t-cells-in-cancer-therapy?uac=148436CN&ecd=wnl_readmost_250103&sso=true&redirected=slug
Angioedema.
Gina Lacuesta, Stephen D Betschel, Ellie Tsai, Harold Kim
Allergy, Asthma, and Clinical Immunology 2024 December 9
https://read.qxmd.com/read/39654054/angioedema?uac=148436CN&ecd=wnl_readmost_250103&sso=true&redirected=slug
The effects of low-dose morphine on sleep and breathlessness in COPD: A randomized trial.
Thomas James Altree, Alison Pinczel, Barbara Toson, Kelly Loffler, Anna Hudson, Jim Zeng, Simon Proctor, Ganesh Naik, Sutapa Mukherjee, Peter Catcheside, Andrew Somogyi, David Currow, Danny Eckert
Chest 2024 December 13
https://read.qxmd.com/read/39675518/the-effects-of-low-dose-morphine-on-sleep-and-breathlessness-in-copd-a-randomized-trial?uac=148436CN&ecd=wnl_readmost_250103&sso=true&redirected=slug
Potential of Sodium-Glucose Cotransporter-2 Inhibitors in the Management of Heart Failure With Preserved Ejection Fraction: A Narrative Review.
Abdulaziz F Alsuwayh, Mohammed Altawili, Marwan Fahad Alhazmi, Dhuha Faisal M Alotaibi, Alghamdi Omar Rashed, Alharbi Hussam Obaid Abdullah, Ahad Ahmad N Alkenani, Rudayna Adel S Almohammdi, Hamad Fahad M Alotaibi, Fatima Essamaldin Altahir Mohamed Alsharif
Curēus 2024 November
https://read.qxmd.com/read/39697908/potential-of-sodium-glucose-cotransporter-2-inhibitors-in-the-management-of-heart-failure-with-preserved-ejection-fraction-a-narrative-review?uac=148436CN&ecd=wnl_readmost_250103&sso=true&redirected=slug
CAR T-cells in autoimmunity: game changer or stepping stone?
Dimitrios Mougiakakos, Everett Meyer, Georg Schett
Blood 2024 December 19
https://read.qxmd.com/read/39700499/car-t-cells-in-autoimmunity-game-changer-or-stepping-stone?uac=148436CN&ecd=wnl_readmost_250103&sso=true&redirected=slug
Antibiotic Treatment of Infections Caused by AmpC-Producing Enterobacterales.
Gianpiero Tebano, Irene Zaghi, Monica Cricca, Francesco Cristini
Pharmacy (Basel, Switzerland) 2024 September 21
https://read.qxmd.com/read/39311133/antibiotic-treatment-of-infections-caused-by-ampc-producing-enterobacterales?uac=148436CN&ecd=wnl_readmost_250103&sso=true&redirected=slug
Exploiting bacteria for cancer immunotherapy.
Seong-Young Kwon, Hien Thi-Thu Ngo, Jinbae Son, Yeongjin Hong, Jung-Joon Min
Nature Reviews. Clinical Oncology 2024 August
https://read.qxmd.com/read/38840029/exploiting-bacteria-for-cancer-immunotherapy?uac=148436CN&ecd=wnl_readmost_250103&sso=true&redirected=slug
Acute myeloid leukemia management and research in 2025. Hagop M Kantarjian, Courtney D DiNardo, Tapan M Kadia, Naval G Daver, Jessica K Altman, Eytan M Stein, Elias Jabbour, Charles A Schiffer, Amy Lang, Farhad Ravandi CA: a Cancer Journal for Clinicians 2024
Acute myeloid leukemia management and research in 2025.
Hagop M Kantarjian, Courtney D DiNardo, Tapan M Kadia, Naval G Daver, Jessica K Altman, Eytan M Stein, Elias Jabbour, Charles A Schiffer, Amy Lang, Farhad Ravandi
CA: a Cancer Journal for Clinicians 2024
https://read.qxmd.com/read/39656142/acute-myeloid-leukemia-management-and-research-in-2025?uac=148436CN&ecd=wnl_readmost_250103&sso=true&redirected=slug
No, Diet and Exercise Are Not Better Than Drugs for Obesity Yoni Freedhoff, MD ++++++
No, Diet & Exercise Are Not Better Than Obesity Drugs
No, Diet and Exercise Are Not Better Than Drugs for Obesity
Yoni Freedhoff, MD
https://www.medscape.com/viewarticle/no-diet-and-exercise-are-not-better-than-drugs-obesity-2024a1000mgl?ecd=mkm_ret_250104_mscpmrk-OUS_InFocus_etid7103891&uac=148436CN&impID=7103891
Injectable Weight Loss Drugs & Environmental Issues
Injectable Weight Loss Drugs: Lifestyle Change for the Environment?
Arthur L. Caplan, PhD
https://www.medscape.com/viewarticle/injectable-weight-loss-drugs-lifestyle-change-environment-2024a1000msg?ecd=mkm_ret_250104_mscpmrk-OUS_InFocus_etid7103891&uac=148436CN&impID=7103891
The Easiest Diet Ever
The Easiest Diet Ever
Tamaan K. Osbourne-Roberts, MD, MBA
https://www.medscape.com/viewarticle/easiest-diet-ever-2024a1000lau?ecd=mkm_ret_250104_mscpmrk-OUS_InFocus_etid7103891&uac=148436CN&impID=7103891
Focus on Nutrient Density, Not Limiting Foods
Focus on Nutrient Density Instead of Limiting Certain Foods
Brandy Winfree Root, RDN
https://www.medscape.com/viewarticle/focus-nutrient-density-instead-limiting-certain-foods-2024a1000lob?ecd=mkm_ret_250104_mscpmrk-OUS_InFocus_etid7103891&uac=148436CN&impID=7103891
Secret to Maintaining Weight Loss With GLP-1s
Maintaining Weight Loss With GLP-1s Needs Lifestyle Changes
Anne L. Peters, MD
https://www.medscape.com/viewarticle/maintaining-weight-loss-glp-1s-needs-lifestyle-changes-2024a1000ld0?ecd=mkm_ret_250104_mscpmrk-OUS_InFocus_etid7103891&uac=148436CN&impID=7103891
Time-Restricted Eating May Improve Metabolic Syndrome
Time-Restricted Eating May Help Adults With Metabolic Syndrome Improve Several Health Markers
Lisa M. Basile
https://www.medscape.com/viewarticle/time-restricted-eating-may-help-adults-metabolic-syndrome-2024a1000hy7?ecd=mkm_ret_250104_mscpmrk-OUS_InFocus_etid7103891&uac=148436CN&impID=7103891
viernes, 3 de enero de 2025
flok, pioneering patient-led research for inherited metabolic disorders (IMD)
https://rarerevolutionmagazine.com/flok-pioneering-patient-led-research-for-inherited-metabolic-disorders-imd/
To bring about a dramatic and wide reaching change in conditions and attitudes for the rare disease community.
https://rarerevolutionmagazine.com/
RARE REV-inar episode 015: Complexities of genetic diagnosis of mitochondrial diseases 16 ene 2025 12:00 p. m.
https://us02web.zoom.us/webinar/register/WN_X5Dwp1NYR6idBch3K5yLtw#/registration
What role have international organizations played in advancing mitochondrial disease advocacy? How has the collaboration between patient advocacy groups and researchers impacted the field? Join our next RARE Rev-inar on January 26th 2025
Six suicide prevention resources all Veterans need to know Programs and initiatives for all Veterans, no matter when or how you served
Six suicide prevention resources all Veterans need to know
Programs and initiatives for all Veterans, no matter when or how you served
https://news.va.gov/137046/six-suicide-prevention-resources-veterans-know/
Tale of Two Tongues: Oral HPV Soars in Young Adults Liz Scherer +++
Tale of Two Tongues: Oral HPV Soars in Young Adults
Liz Scherer
https://www.medscape.com/s/viewarticle/tale-two-tongues-oral-hpv-soars-young-adults-2024a1000ax7?ecd=mkm_ret_250103_mscpmrk_onc_youth_etid7134120&uac=148436CN&impID=7134120
Many Young Adults Who Vaped As Teens Can't Shake the Habit
John Daley
https://www.medscape.com/s/viewarticle/many-young-adults-who-vaped-teens-cant-shake-habit-2024a1000b1l?ecd=mkm_ret_250103_mscpmrk_onc_youth_etid7134120&uac=148436CN&impID=7134120
Does Marijuana Harm Your Lungs? The Unclear Truth
Aaron B. Holley, MD
https://www.medscape.com/viewarticle/does-marijuana-harm-your-lungs-unclear-truth-2024a1000mou?ecd=mkm_ret_250103_mscpmrk_onc_youth_etid7134120&uac=148436CN&impID=7134120
How Many Young Breast Cancer Survivors Struggle Financially? Edited by Gargi Mukherjee ++++
PATIENT OUTCOMES
Preventive Surgeries Help Young BRCA Patients: New Data
Do Risk-Reducing Surgeries Benefit BRCA Carriers With Early-Onset Breast Cancer History?
Megan Brooks
https://www.medscape.com/viewarticle/do-risk-reducing-surgeries-benefit-brca-carriers-early-onset-2024a1000myt?ecd=mkm_ret_250103_mscpmrk_onc_youth_etid7134120&uac=148436CN&impID=7134120
Unique Challenges, Top Concerns of Young Patients With CRC Identified
What Matters Most for Young Patients With CRC: Survey Highlights Top Concerns
Megan Brooks
https://www.medscape.com/viewarticle/what-matters-most-young-patients-crc-survey-highlights-top-2024a1000ki2?ecd=mkm_ret_250103_mscpmrk_onc_youth_etid7134120&uac=148436CN&impID=7134120
CAR T for B-ALL: Game Changer for Young Patients?
CAR T for B-ALL: Game Changer for Young Patients?
Randy Dotinga
https://www.medscape.com/s/viewarticle/car-t-b-all-game-changer-young-patients-2024a1000aq2?ecd=mkm_ret_250103_mscpmrk_onc_youth_etid7134120&uac=148436CN&impID=7134120
Financial Struggles of Young Breast Cancer Survivors
How Many Young Breast Cancer Survivors Struggle Financially?
Edited by Gargi Mukherjee
https://www.medscape.com/viewarticle/how-many-young-breast-cancer-survivors-struggle-financially-2024a1000mg4?ecd=mkm_ret_250103_mscpmrk_onc_youth_etid7134120&uac=148436CN&impID=7134120
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