lunes, 31 de marzo de 2025

Harnessing AI to combat rheumatoid arthritis

https://www.news-medical.net/news/20250318/Harnessing-AI-to-combat-rheumatoid-arthritis.aspx?utm_source=news_medical_newsletter&utm_medium=email&utm_campaign=arthritis_newsletter_24_march_2025

Arthritis and COPD together raise mortality risk

https://www.news-medical.net/news/20250311/Arthritis-and-COPD-together-raise-mortality-risk.aspx?utm_source=news_medical_newsletter&utm_medium=email&utm_campaign=arthritis_newsletter_24_march_2025

The Rise of Postbiotics for Gut Health

https://www.news-medical.net/health/The-Rise-of-Postbiotics-for-Gut-Health.aspx?utm_source=news_medical_newsletter&utm_medium=email&utm_campaign=arthritis_newsletter_24_march_2025

Natural ingredient gluconolactone offers hope for targeted lupus therapy

https://www.news-medical.net/news/20250312/Natural-ingredient-gluconolactone-offers-hope-for-targeted-lupus-therapy.aspx?utm_source=news_medical_newsletter&utm_medium=email&utm_campaign=arthritis_newsletter_24_march_2025

Atrial fibrillation elevates early-onset dementia risk in younger adults

https://www.news-medical.net/news/20250331/Atrial-fibrillation-elevates-early-onset-dementia-risk-in-younger-adults.aspx

Antidepressant use associated with higher risk of sudden cardiac death in all age groups

https://www.news-medical.net/news/20250331/Antidepressant-use-associated-with-higher-risk-of-sudden-cardiac-death-in-all-age-groups.aspx

Ibuprofen suppresses sweet taste perception

https://www.news-medical.net/news/20250331/Ibuprofen-suppresses-sweet-taste-perception.aspx

Traditional Chinese medicine targets cholesterol metabolism for cancer treatment

https://www.news-medical.net/news/20250331/Traditional-Chinese-medicine-targets-cholesterol-metabolism-for-cancer-treatment.aspx

Heart attack deaths during marathons decline significantly, study reveals

https://www.news-medical.net/news/20250331/Heart-attack-deaths-during-marathons-decline-significantly-study-reveals.aspx

Assessing the impact of the particle drift effect on oral drug absorption using flux tools

https://www.news-medical.net/news/20250331/Assessing-the-impact-of-the-particle-drift-effect-on-oral-drug-absorption-using-flux-tools.aspx

Exploring exosomal RNA as a biomarker for prostate cancer detection

https://www.news-medical.net/whitepaper/20250331/Exploring-exosomal-RNA-as-a-biomarker-for-prostate-cancer-detection.aspx

How bacteria develop antibiotic resistance and what science is doing about it

https://www.news-medical.net/whitepaper/20250331/How-bacteria-develop-antibiotic-resistance-and-what-science-is-doing-about-it.aspx

Can Red Light Therapy Improve Sleep, Skin, and Recovery?

https://www.news-medical.net/health/Can-Red-Light-Therapy-Improve-Sleep-Skin-and-Recovery.aspx

How Artificial Sweeteners Disrupt the Gut Microbiome, Or Do They?

https://www.news-medical.net/health/How-Artificial-Sweeteners-Disrupt-the-Gut-Microbiome-Or-Do-They.aspx

Understanding the Nervous System Dysregulation

https://www.news-medical.net/health/Understanding-the-Nervous-System-Dysregulation.aspx

Can brain-healthy eating improve your quality of life? This study tested it

https://www.news-medical.net/news/20250330/Can-brain-healthy-eating-improve-your-quality-of-life-This-study-tested-it.aspx

Human Monoclonal Antibodies That Target the RH5 Complex of Blood-Stage Plasmodium Falciparum

https://www.techtransfer.nih.gov/tech/tab-4473?utm_campaign=+64396199&utm_content=&utm_medium=email&utm_source=govdelivery&utm_term=

FDA expands Pluvicto’s metastatic castration-resistant prostate cancer indication

https://www.fda.gov/drugs/resources-information-approved-drugs/fda-expands-pluvictos-metastatic-castration-resistant-prostate-cancer-indication

FDA approves durvalumab for muscle invasive bladder cancer

https://www.fda.gov/drugs/resources-information-approved-drugs/fda-approves-durvalumab-muscle-invasive-bladder-cancer

domingo, 30 de marzo de 2025

Daily physical activity, even at light intensities, linked to lower cancer risk NIH study finds number of steps taken daily may be more important for cancer risk than the intensity of activity.

https://www.nih.gov/news-events/news-releases/daily-physical-activity-even-light-intensities-linked-lower-cancer-risk

Disease Screenings | Autoimmune Diseases | Preeclampsia | Alcohol-Induced Blackouts | Heart Health Numbers

https://content.govdelivery.com/accounts/USNIH/bulletins/3d74e4b?reqfrom=share

Weekly Rundown: Myelin may act as a fuel source during marathons A landmark UTI drug approval, new hope for the amyloid hypothesis in Alzheimer’s disease, a brewing vaccine study controversy, and more led the news this week.

https://www.drugdiscoverynews.com/weekly-rundown-myelin-may-act-as-a-fuel-source-during-marathons-16284

Advancing the understanding and management of angioimmunoblastic T-cell lymphoma: insights into its pathogenesis, clinical features, and emerging therapeutic strategies.

https://read.qxmd.com/collection/1133?ecd=wnl_readmost_250328

Withdrawal of life sustaining therapies in patients with or without acute brain injury +++

COMMENTS Withdrawal of life sustaining therapies in patients with or without acute brain injury Free with registration https://www.thelancet.com/journals/lanres/article/PIIS2213-2600(25)00008-6/abstract?utm_campaign=conferencealerts&utm_medium=email&dgcid=hubspot_email_conferencealerts_isicem25&_hsenc=p2ANqtz-810NB0yb5F8Y3mQoTvgEnf3PBxQ_x-1_TZ_8qLvO7IHfC9d4cH8fwl837ny6wVo7ZBi_HMBcBsoxGB_MQIwToj-LKXew&_hsmi=352808950&utm_content=352808950&utm_source=hs_email Preoxygenation for tracheal intubation in adults who are critically ill: time to abandon the facemask? Free with registration https://www.thelancet.com/journals/lanres/article/PIIS2213-2600(25)00056-6/abstract?utm_campaign=conferencealerts&utm_medium=email&dgcid=hubspot_email_conferencealerts_isicem25&_hsenc=p2ANqtz-_O2ezWCvjfoZz5Q5ESOfmMX6NmtsAph4KPJkiMLFDXsHHDjpAl6I4HvHH8Ww64Xvi02BFm_leL5eaPP96IfcdY-QCaLA&_hsmi=352808950&utm_content=352808950&utm_source=hs_email Nasal high-flow oxygen for apnoeic oxygenation during emergency endotracheal intubation of children Free with registration until Mar 29, 2025 https://www.thelancet.com/journals/lanres/article/PIIS2213-2600(25)00085-2/abstract?utm_campaign=conferencealerts&utm_medium=email&dgcid=hubspot_email_conferencealerts_isicem25&_hsenc=p2ANqtz--vIxGOCPiYLzDZXz_tTE-g7z71XuylR7mYeYYxliVH1B5fYWRJq79KXw5gzRg4Z2kKmV_acKuRo7B_XU9omyDPco3h-Q&_hsmi=352808950&utm_content=352808950&utm_source=hs_email

Decisions to withdraw or withhold life-sustaining therapies in patients with and without acute brain injury: a secondary analysis of two prospective cohort studies +++

Decisions to withdraw or withhold life-sustaining therapies in patients with and without acute brain injury: a secondary analysis of two prospective cohort studies Free with registration https://www.thelancet.com/journals/lanres/article/PIIS2213-2600(24)00404-1/abstract?utm_campaign=conferencealerts&utm_medium=email&dgcid=hubspot_email_conferencealerts_isicem25&_hsenc=p2ANqtz-9yZxutbZcCCq90aHFGFVGigqyWw0ryhTVRtZORXNKm5SfJl2a2q36-jaAm66P9iSc_Ff7A_ocSAOASqzeQZxPim9GNCA&_hsmi=352808950&utm_content=352808950&utm_source=hs_email Preoxygenation strategies for intubation of patients who are critically ill: a systematic review and network meta-analysis of randomised trials Free with registration https://www.thelancet.com/journals/lanres/article/PIIS2213-2600(25)00029-3/abstract?utm_campaign=conferencealerts&utm_medium=email&dgcid=hubspot_email_conferencealerts_isicem25&_hsenc=p2ANqtz-8YsCucNxqabXI7lq-b43RHwLyzSAs9pQQTyNsn-LUHgTnhstNAOxLwjykk17dC8vGq4bSbqM1mRCOCdC5KHUt9vuGqwg&_hsmi=352808950&utm_content=352808950&utm_source=hs_email Effectiveness of nasal high-flow oxygen during apnoea on hypoxaemia and intubation success in paediatric emergency and ICU settings: a randomised, controlled, open-label trial Free with registration https://www.thelancet.com/journals/lanres/article/PIIS2213-2600(25)00074-8/abstract?utm_campaign=conferencealerts&utm_medium=email&dgcid=hubspot_email_conferencealerts_isicem25&_hsenc=p2ANqtz-8jUBeMLPijDy0bwg1TQH1_RbLw2zWd7vX1hcRb35Aj7gT-MdubfKY9D3CrwuuA-UaW9JbfTZyquqOSQMhV3_YzefrtNQ&_hsmi=352808950&utm_content=352808950&utm_source=hs_email

Game On! Play Your Way to Financial Freedom By Ivanhoe Broadcast News on April 4, 2025

Game On! Play Your Way to Financial Freedom By Ivanhoe Broadcast News on April 4, 2025 https://www.ivanhoe.com/?p=35258&preview=1&_ppp=199a418261

The Big Disconnect: How To Hang Up And Reconnect With Family By Ivanhoe Broadcast News on March 27, 2025

The Big Disconnect: How To Hang Up And Reconnect With Family By Ivanhoe Broadcast News on March 27, 2025 https://www.ivanhoe.com/smart-living/the-big-disconnect-how-to-hang-up-and-reconnect-with-family/

Don’t Get Scammed! How To Spot Fake Job Ads By Ivanhoe Broadcast News on April 2, 2025

Don’t Get Scammed! How To Spot Fake Job Ads By Ivanhoe Broadcast News on April 2, 2025 https://www.ivanhoe.com/?p=35252&preview=1&_ppp=30c768429d

Sun, Sand And Scams! Spring Break Beware! By Ivanhoe Broadcast News on April 1, 2025

Sun, Sand And Scams! Spring Break Beware! By Ivanhoe Broadcast News on April 1, 2025 https://www.ivanhoe.com/?p=35249&preview=1&_ppp=3f10dc9fd2

RESILIENT ROOTS: EMPOWERING LATINO COMMUNITIES TO THRIVE

Resilient Roots: Empowering Latino Communities to Thrive By Ivanhoe Broadcast News on March 31, 2025 https://www.ivanhoe.com/?p=35205&preview=1&_ppp=8ed3416d74

FDA Approves Novel Treatment for Hemophilia A or B, with or without Factor Inhibitors Medication Can be Given Up to Once Every 2 Months

https://www.fda.gov/news-events/press-announcements/fda-approves-novel-treatment-hemophilia-or-b-or-without-factor-inhibitors?utm_medium=email&utm_source=govdelivery

FDA expands Pluvicto’s metastatic castration-resistant prostate cancer indication - lutetium Lu 177 vipivotide tetraxetan (Pluvicto, Novartis Pharmaceuticals Corporation)

https://www.fda.gov/drugs/resources-information-approved-drugs/fda-expands-pluvictos-metastatic-castration-resistant-prostate-cancer-indication

Advancing Precision Cancer Medicine: Unveiling the Future Frontier Do you know how precision medicine is shaping the future of cancer care?

https://www.medscape.org/viewarticle/advancing-precision-cancer-medicine-unveiling-future-2025a10000dr?sso=true&uac=148436CN&src=mkmcmr_driv_stan_mscpedu_250329-OUS-HONC-advancing-precision-cancer-medicine-unveiling-future-2025a10000dr-cta

High-Dose Vitamin D Curbs Disease Activity in Early Multiple Sclerosis Megan Brooks March 13, 2025 +++++ +++

BREAKTHROUGHS & SETBACKS High-Dose Vitamin D Tames Early MS High-Dose Vitamin D Curbs Disease Activity in Early Multiple Sclerosis Megan Brooks March 13, 2025 https://www.medscape.com/viewarticle/high-dose-vitamin-d-curbs-disease-activity-early-multiple-2025a100062t?ecd=mkm_ret_250329_mscpmrk_neuro_topcontent_etid7324753&uac=148436CN&impID=7324753 Neurologic Dysfunction & Microplastics Linked Marine Microplastics Linked to Neurologic Dysfunction Megan Brooks March 07, 2025 https://www.medscape.com/viewarticle/marine-microplastics-linked-neurologic-dysfunction-2025a10005na?ecd=mkm_ret_250329_mscpmrk_neuro_topcontent_etid7324753&uac=148436CN&impID=7324753 MS Subtyping: Does It Really Matter? Is MS Subtyping Clinically Meaningful? Experts Weigh In Ted Bosworth March 14, 2025 https://www.medscape.com/viewarticle/ms-subtyping-clinically-meaningful-experts-weigh-2025a100066h?ecd=mkm_ret_250329_mscpmrk_neuro_topcontent_etid7324753&uac=148436CN&impID=7324753 Stopping DMTs in Older MS Patients: What the Data Show Stopping DMTs in Older MS Patients: What the Data Show Ted Bosworth March 03, 2025 https://www.medscape.com/viewarticle/stopping-dmts-older-ms-patients-what-data-show-2025a100058n?ecd=mkm_ret_250329_mscpmrk_neuro_topcontent_etid7324753&uac=148436CN&impID=7324753 Teen's Death Raises Concerns for Gene Therapy Tx Sarepta Says Teen Died After Its Gene Therapy Treatment Sriparna Roy And Bhanvi Satija March 18, 2025 https://www.medscape.com/s/viewarticle/sarepta-reports-teen-death-after-gene-therapy-treatment-2025a10006h3?ecd=mkm_ret_250329_mscpmrk_neuro_topcontent_etid7324753&uac=148436CN&impID=7324753 GUIDELINES & CLINICAL INSIGHTS New Guidance on Seizures, Driving, and Medical Reporting New Guidance on Seizures, Driving, and Medical Reporting Patrice Wendling March 12, 2025 https://www.medscape.com/viewarticle/new-guidance-seizures-driving-and-medical-reporting-2025a1000621?ecd=mkm_ret_250329_mscpmrk_neuro_topcontent_etid7324753&uac=148436CN&impID=7324753 How to Deliver a Dementia Diagnosis Breaking Bad News: Guidance on Disclosing a Dementia Diagnosis Megan Brooks March 03, 2025 https://www.medscape.com/viewarticle/breaking-bad-news-guidance-disclosing-dementia-diagnosis-2025a100057h?ecd=mkm_ret_250329_mscpmrk_neuro_topcontent_etid7324753&uac=148436CN&impID=7324753 OTC Analgesics Improve Concussion Outcomes Over-the-Counter Analgesics Improve Concussion Outcomes Pauline Anderson March 13, 2025 https://www.medscape.com/viewarticle/over-counter-analgesics-improve-concussion-outcomes-2025a100063h?ecd=mkm_ret_250329_mscpmrk_neuro_topcontent_etid7324753&uac=148436CN&impID=7324753

Safety and efficacy of atorvastatin for rebleeding in cerebral cavernous malformations (AT CASH EPOC): a phase 1/2a, randomised placebo-controlled trial

https://www.thelancet.com/collections/neurology?dgcid=hubspot_email_infocusalerts-neurology_feature&parent=001585&startPage=&ContentItemType=fla&utm_campaign=infocusalerts-neurology&utm_medium=email&_hsenc=p2ANqtz-9QoxAmrt0D3ejRqtAYYWr9LGFF2VM09Jxpvnx_hdyV61OZe9YzcQnm1A5X3qz-YLA_RWXPw74EZ_uoifElT1Rp-_oyAQ&_hsmi=353495300&utm_content=353495300&utm_source=hs_email

Hot Brain 3: climate change and brain health 20 May 2025, 9:00 am–5:00 pm

https://www.ucl.ac.uk/ion/events/2025/may/hot-brain-3-climate-change-and-brain-health?utm_campaign=infocusalerts-neurology&utm_medium=email&_hsenc=p2ANqtz-_TittzrqErbg0L0v2GlbeyxXCSmrENLdSa3YS5g6GN4IgbS8xCBs6OiDk_Vyii7JGh_l93uPYWtpUadhzQLHGw2P4LiA&_hsmi=353495300&utm_content=353495300&utm_source=hs_email

Global, regional, and national burden of epilepsy, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021

https://www.thelancet.com/journals/lanpub/article/PIIS2468-2667(24)00302-5/fulltext?dgcid=hubspot_email_infocusalerts-neurology_feature&utm_campaign=infocusalerts-neurology&utm_medium=email&_hsenc=p2ANqtz--sG8jMcV8PGbUON-RxfdO8dHJeBiO3UG8HZlLzKByI-yyx6dCpw0c6Tt8VhBHK6qOjER_GrasTX4LSSEkaHqbRi__9Zw&_hsmi=353495300&utm_content=353495300&utm_source=hs_email

Global, regional, and national burden of suicide, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021

https://www.thelancet.com/journals/lanpub/article/PIIS2468-2667(25)00006-4/fulltext?dgcid=hubspot_email_infocusalerts-psychiatry_feature&utm_campaign=infocusalerts-psychiatry&utm_medium=email&_hsenc=p2ANqtz--rL6jXqrrTYWLnE0G_V4qEWjQW7xEV37JE1gjL6MSZwmKN62h6hpnuIHP1Ya7dIZNXlEStJrLZFQxf_rsq33kOqJU9Dw&_hsmi=353494235&utm_content=353494235&utm_source=hs_email

Trump 2.0: a better way to show leadership The Lancet Psychiatry

https://www.thelancet.com/journals/lanpsy/issue/vol12no3/PIIS2215-0366(25)X0003-1

Mentalisation-based treatment for antisocial personality disorder in males convicted of an offence on community probation in England and Wales (Mentalization for Offending Adult Males, MOAM): a multicentre, assessor-blinded, randomised controlled trial

https://www.thelancet.com/journals/lanpsy/article/PIIS2215-0366(24)00445-0/abstract?utm_campaign=infocusalerts-psychiatry&utm_medium=email&dgcid=hubspot_email_infocusalerts-psychiatry_feature&_hsenc=p2ANqtz-8qChaSujZtleDH15Vvt7G9yz34pSTpBCI9WuuqwysxhuFDYUZo67EtHgX8ac8hbTf38eZUynVlj5MSpLJeUdSu9jFO_Q&_hsmi=353494235&utm_content=353494235&utm_source=hs_email

sábado, 29 de marzo de 2025

Stratifying Risk: Reducing Recurrence in Early Breast Cancer

https://www.medscape.com/mtv/breast-cancer-ous-s02/e01?src=vid_pil

Essential Tremor: Evolving Innovations in Treatment

https://www.medscape.com/mtv/essential-tremor-ous-s01/e01?src=vid_pil

Renal Cell Carcinoma Highlights From ASCO GU 2025 Eric Jonasch, MD | March 06, 2025

https://www.medscape.com/viewarticle/conf-recap-asco-gu-rcc-2024a1000p8g

Ovarian Cancer Highlights From ESGO 2025 Kathleen N. Moore, MD | March 14, 2025

https://www.medscape.com/viewarticle/esgo-2025-ovarian-cancer-2025a10001ze

Key Updates in Disease-Modifying Therapies for RRMS From ACTRIMS 2025 Pavan Bhargava, MD | March 20, 2025

https://www.medscape.com/viewarticle/ms-relapse-remittent-dmt-actrims2025-2025a100007f

Urticaria, Angioedema, and Anaphylaxis Highlights From AAAAI Ruchi Gupta, MD, MPH | March 24, 2025

https://www.medscape.com/viewarticle/aaaai-2025-anaphylaxis-urticaria-angioedema-highlights-2025a10000a7

Advancing Patient-Centered Care in mCRPC: Exploring PARP Inhibitor Combinations

https://www.medscape.org/oncology

Bowel Prep for Colonoscopy: Quality Matters David A. Johnson, MD | March 27, 2025

https://www.medscape.com/viewarticle/bowel-prep-colonoscopy-quality-matters-2025a10007al

The Mental Impact of Multicancer Early-Detection Testing David J. Kerr, MA, MD | March 28, 2025

https://www.medscape.com/viewarticle/mental-impact-multicancer-early-detection-testing-2025a10006pn

When a Cancer Drug Shortens Life: Lessons From ARIEL4 Bishal Gyawali, MD, PhD | March 25, 2025

https://www.medscape.com/viewarticle/when-cancer-drug-shortens-life-lessons-ariel4-2025a10006uc

How Lifetime Weight Patterns Influence Kidney Cancer Risk Edited by Gargi Mukherjee March 28, 2025

https://www.medscape.com/viewarticle/how-lifetime-weight-patterns-influence-kidney-cancer-risk-2025a10007gv

Inadequate Grading of Intraductal Carcinoma of the Prostate Nancy A. Melville March 28, 2025

https://www.medscape.com/viewarticle/inadequate-grading-intraductal-carcinoma-prostate-2025a10007fu

Pirtobrutinib’s Star Turn in Relapsed/Refractory CLL May Get an Encore Randy Dotinga March 28, 2025

https://www.medscape.com/viewarticle/pirtobrutinibs-star-turn-relapsed-refractory-cll-may-get-2025a10007ha

Fitusiran Approved for Hemophilia A, B M. Alexander Otto, PA, MMS March 28, 2025

https://www.medscape.com/viewarticle/fitusiran-approved-hemophilia-b-2025a10007k7

Microultrasonography Rivals MRI in Prostate Cancer Detection Edited by Anushree Chaphalkar March 28, 2025

https://www.medscape.com/viewarticle/microultrasonography-rivals-mri-prostate-cancer-detection-2025a100076b

‘Take a Photograph’: Trial Shows Big Survival Gain in Advanced EGFR-Mutant NSCLC Megan Brooks March 28, 2025

https://www.medscape.com/viewarticle/take-photograph-trial-shows-big-survival-gain-advanced-egfr-2025a10007fr

Does Higher Dairy Intake Reduce CRC Risk? Tara Haelle

https://www.medscape.com/viewarticle/does-higher-dairy-intake-reduce-crc-risk-2025a10007fn

A ‘Fool’s Errand’? Picking a Winner for Treating Early-Stage NSCLC Megan Brooks March 27, 2025

https://www.medscape.com/viewarticle/fools-errand-picking-winner-treating-early-stage-nsclc-2025a10007dg

Treatment & Guidelines: ASCO Updates Treatment Guidance for Newly Diagnosed, Advanced Ovarian Cancer Christos Evangelou, MSc, PhD ++++ ++++

Treatment & Guidelines ASCO Guidelines: Ovarian Cancer Updates ASCO Updates Treatment Guidance for Newly Diagnosed, Advanced Ovarian Cancer Christos Evangelou, MSc, PhD February 24, 2025 https://www.medscape.com/viewarticle/asco-updates-treatment-guidance-newly-diagnosed-advanced-2025a10004ox?ecd=mkm_ret_250329_mscpmrk_onc-gyno_etid7324513&uac=148436CN&impID=7324513 Cervical Cancer: Does Adding Chemo to RT Improve Survival? Does Adding Adjuvant Chemo to Radiation Improve Survival in Early Cervical Cancer? Megan Brooks March 24, 2025 https://www.medscape.com/viewarticle/does-adding-adjuvant-chemo-radiation-improve-survival-early-2025a10006xd?ecd=mkm_ret_250329_mscpmrk_onc-gyno_etid7324513&uac=148436CN&impID=7324513 Pembrolizumab Improves PFS in Cervical Cancer Pembrolizumab Improves 36-Month PFS in Cervical Cancer Jim Kling March 18, 2025 https://www.medscape.com/viewarticle/pembrolizumab-improves-36-month-pfs-cervical-cancer-2025a10006gu?ecd=mkm_ret_250329_mscpmrk_onc-gyno_etid7324513&uac=148436CN&impID=7324513 Is Adjuvant Chemo Necessary for Intermediate-Risk Cervical Cancer? Do Patients With Intermediate-Risk Cervical Cancer Need Adjuvant Chemotherapy? Whitney McKnight March 20, 2025 https://www.medscape.com/viewarticle/do-patients-intermediate-risk-cervical-cancer-need-adjuvant-2025a10006q4?ecd=mkm_ret_250329_mscpmrk_onc-gyno_etid7324513&uac=148436CN&impID=7324513 Detection & Research Tampon Test for Endometrial Cancer Tampon-Based Test Detects Endometrial Cancer Using Vaginal Fluid Biomarkers M. Alexander Otto, PA, MMS March 25, 2025 https://www.medscape.com/viewarticle/tampon-based-test-detects-endometrial-cancer-using-vaginal-2025a1000706?ecd=mkm_ret_250329_mscpmrk_onc-gyno_etid7324513&uac=148436CN&impID=7324513 Risk-Reduction Surgery Benefit in Non-BRCA Ovarian Cancer? TNBC Outcomes Show Progress Medscape Medical News March 28, 2025 https://www.medscape.com/resource/ovarian-cancer?ecd=mkm_ret_250329_mscpmrk_onc-gyno_etid7324513&uac=148436CN&impID=7324513 Adjuvant Chemo vs Radiotherapy Alone in Cervical Cancer Do Patients With Intermediate-Risk Cervical Cancer Need Adjuvant Chemotherapy? Whitney McKnight March 20, 2025 https://www.medscape.com/viewarticle/do-patients-intermediate-risk-cervical-cancer-need-adjuvant-2025a10006q4?ecd=mkm_ret_250329_mscpmrk_onc-gyno_etid7324513&uac=148436CN&impID=7324513 What's New in Endometrial Cancer Research? Endometrial Cancer: Molecular Classification, Genetics, When to Rebiopsy, and What's New in the Research Ursula A. Matulonis, MD; Katherine Fuh, MD, PhD https://www.medscape.com/viewarticle/1001980?ecd=mkm_ret_250329_mscpmrk_onc-gyno_etid7324513&uac=148436CN&impID=7324513 March 12, 2025

Why is this startup growing synthetic brains from urine? By Zachy Hennessey March 25, Updated March 27

Why is this startup growing synthetic brains from urine? Itay&Beyond grows brain tissue from patient urine stem cells to test neurological drugs, training the chips via video games to detect autism and other brain disorders. https://www.israel21c.org/why-is-this-startup-growing-synthetic-brains-from-urine/

jueves, 27 de marzo de 2025

Advancing immune forces at the tumor frontlines Epigenetic therapies revive the immune cell offensive in immunotherapy resistant tumors.

https://www.drugdiscoverynews.com/advancing-immune-forces-at-the-tumor-frontlines-15748?utm_campaign=DDN_Newsletter_Dose&utm_medium=email&_hsenc=p2ANqtz-_V7Kg1WgHbHpuNY51X3sIgSAEUEuKMakhAIbV_YoG--PZ-a016GOMVgkDO0aLhLN_iVOEE6w-C4sopxSQKTWvH2m5dCA&_hsmi=353912764&utm_content=353912764&utm_source=hs_email

Overcoming delivery hurdles, IL-12 tackles ovarian cancer A targeted interleukin-12 gene therapy plus chemotherapy increased survival in advanced ovarian cancer, setting the stage for a new first-line drug.

https://www.drugdiscoverynews.com/overcoming-delivery-hurdles-il-12-tackles-ovarian-cancer-16283?utm_campaign=DDN_Newsletter_Dose&utm_medium=email&_hsenc=p2ANqtz-88LqTuiJ3sAh68iF3XqovoMS9NEFyM8LhDUvfpExh1ygOn2n0vP93krwlqbm1STvTzsgxNFsP0ZlSOJsJVzgr4cP7zDA&_hsmi=353912764&utm_content=353912764&utm_source=hs_email

In a first, Eli Lilly to connect patients to telehealth providers of Alzheimer’s care The move by Lilly, which sells a treatment for the condition, is part of a direct-to-consumer push that has drawn scrutiny Manage alerts for this article Email this article

https://www.statnews.com/2025/03/27/eli-lilly-alzheimers-disease-telemedicine-synapticure/?utm_campaign=daily_recap&utm_medium=email&_hsenc=p2ANqtz-_hupyD3lL6RBtOP9CMFkNgi18kgiqQy4Cg9XMKVg6iuLuC-vzjjc8G0DWOKbfQFvzE9qqUy2FAQ3MbEIHFdUBhFmm7UQ&_hsmi=353971064&utm_content=353971064&utm_source=hs_email

As the Trump administration withdraws support for biotechnology innovation pushed by former president Biden, Europe is poised to seize the initiative Thomas Gabrielczyk | European Biotechnology | March 26, 2025

https://geneticliteracyproject.org/2025/03/26/as-the-trump-administration-withdraws-support-for-biotechnology-innovation-pushed-by-former-president-biden-europe-is-poised-to-seize-the-initiative/?mc_cid=1fe209ae04&mc_eid=b73600b7ac

To evaluate non-existent links of vaccines to autism, RFK, Jr. taps activist who faked being a doctor, published “research”—later retracted—claiming a ‘vaccine-autism’ link and administered ineffective drugs to children to “cure” autism Fenit Nirappil, Lena Sun | Washington Post | March 27, 2025

https://geneticliteracyproject.org/2025/03/27/to-evaluate-non-existent-links-of-vaccines-to-autism-rfk-jr-taps-activist-who-faked-being-a-doctor-published-research-later-retracted-claiming-a-vaccine-autism-link-and-adm/?mc_cid=1fe209ae04&mc_eid=b73600b7ac

Viewpoint: Texas is a measles superspreader: With anti-vaccination ideology surging, the state is exporting the pandemic crisis to the rest of the US and the world Stephen Simpson | ABC News | March 27, 2025

https://geneticliteracyproject.org/2025/03/27/viewpoint-texas-is-a-measles-superspreader-with-anti-vaccination-ideology-surging-the-state-is-exporting-the-pandemic-crisis-to-the-rest-of-the-us-and-the-world/?mc_cid=1fe209ae04&mc_eid=b73600b7ac

Bird Flu Knowledge, Misleading Claims About Measles Prevention, and Health Content Restrictions Irving Washington, Hagere Yilma, and Joel Luther

https://www.kff.org/the-monitor/bird-flu-knowledge-misleading-claims-about-measles-prevention-and-health-content-restrictions/?utm_campaign=KFF-Misinformation-Trust&utm_medium=email&_hsenc=p2ANqtz-_ZZFrQqt576WQ48MzukFKj1V-WkyiZQHBgf8yT-ZBx9A42pqIj5OKMyjjDGfhwW3oLkqK-lpFVuBMGHRW5ejrIgbJR_A&_hsmi=353750856&utm_content=353750856&utm_source=hs_email

Measles, Mumps, Rubella (MMR) Vaccine Safety

https://www.cdc.gov/vaccine-safety/vaccines/mmr.html?utm_campaign=KFF-Misinformation-Trust&utm_medium=email&_hsenc=p2ANqtz-_Ivm53g2l1qtrklMu_Nk0g8OgvzYc7KQstaaW_frupCuuvTPbnxq1FtJkIraWnY5daZL-xLsV9YPBKLl0b37p6Shy9Aw&_hsmi=353750856&utm_content=353750856&utm_source=hs_email

Measles

https://www.who.int/news-room/fact-sheets/detail/measles?utm_campaign=KFF-Misinformation-Trust&utm_medium=email&_hsenc=p2ANqtz-8cNTnoHbDFX7Pzcb09DYrmI45MIoDIXVCm0ysGFbVIBCCamxwK2Vvjc6K8RXT-rVMeycNya-tZnmH6X75lD_8RJP0F5Q&_hsmi=353750856&utm_content=353750856&utm_source=hs_email

Clinical Overview of Measles

https://www.cdc.gov/measles/hcp/clinical-overview/index.html?utm_campaign=KFF-Misinformation-Trust&utm_medium=email&_hsenc=p2ANqtz--19SageLyhT8c8A6goBHXPJz2B1oZOysL56qay0rx8WE5pftIFp2yRSNQ8uYnK-Z8bNPNpZMKfBU_1QT0zl5ur-cy7nA&_hsmi=353750856&utm_content=353750856&utm_source=hs_email

Prevention and Antiviral Treatment of Avian Influenza A Viruses in People

https://www.cdc.gov/bird-flu/prevention/index.html?utm_campaign=KFF-Misinformation-Trust&utm_medium=email&_hsenc=p2ANqtz-8M4iez0lzy9_6rcuTCGrI7Zr2V8j-scX2ShzcQ6l08VKB239PLWo5n1Z7MRgm2jPM1VgrFEPjMe3rds8JBsyiS7nFBoA&_hsmi=353750856&utm_content=353750856&utm_source=hs_email

New pancreatic cancer research may improve detection and treatment NIH funds studies on this challenging disease

https://magazine.medlineplus.gov/article/new-pancreatic-cancer-research-may-improve-detection-and-treatment?utm_medium=email&utm_source=govdelivery

Pain: Considering Complementary Approaches (eBook)

https://www.nccih.nih.gov/health/pain-considering-complementary-approaches-ebook?nav=govd

New Survey Shows U.S. Veterans’ Use of Natural Products for Chronic Pain

https://www.nccih.nih.gov/research/research-results/new-survey-shows-us-veterans-use-of-natural-products-for-chronic-pain?nav=govd

Multiple Sclerosis and Complementary Health Approaches March 2025

https://www.nccih.nih.gov/health/providers/digest/multiple-sclerosis-and-complementary-health-approaches?nav=govd

Daily physical activity, even at light intensities, linked to lower cancer risk

https://www.cancer.gov/news-events/press-releases/2025/light-intensity-physical-activity-cancer-risk?cid=eb_govdel

Experimental Treatment Uses Engineered Fat Cells to “Starve” Tumors

https://www.cancer.gov/news-events/cancer-currents-blog/2025/starving-tumors-engineered-fat-cells?cid=eb_govdel

Predictive Models Show Promise in Preventing Suicide March 27, 2025 • Research Highlight

https://www.nimh.nih.gov/news/science-updates/2025/predictive-models-show-promise-in-preventing-suicide

Serious liver injury being observed in patients without cirrhosis taking...

Sexually Transmitted Infections in Women – OWH Speaker Series

LEADER 3D: Challenges, Strategies & Regulatory Considerations for Rare D...

Considerations for Collecting/Using Natural History Data Fit for Use in ...

Understanding Endpoints in Rare Disease Drug Development

Learning and Education to ADvance and Empower Rare Disease Drug Developers (LEADER 3D)

https://www.fda.gov/about-fda/accelerating-rare-disease-cures-arc-program/learning-and-education-advance-and-empower-rare-disease-drug-developers-leader-3d?utm_medium=email&utm_source=govdelivery Now Available: Two LEADER 3D Videos on Understanding the Importance of Endpoints and Considerations for Collecting and Using Natural History Data The CDER ARC Program’s Learning and Education to ADvance and Empower Rare Disease Drug Developers (LEADER 3D) initiative published two new videos titled “Understanding the Importance of Endpoints in Rare Disease Drug Development” and “Considerations for Collecting and Using Natural History Study Data that are Fit for Use in the Regulatory Setting” to the educational video series. The videos provide an overview of important considerations for selecting endpoints when designing clinical trials, and concepts to consider when determining how to leverage natural history study data in rare disease drug development programs.

miércoles, 26 de marzo de 2025

Tiny tardigrades may hold clues to cancer care

https://www.nih.gov/news-events/nih-research-matters/tiny-tardigrades-may-hold-clues-cancer-care

Non-opioid compound for chronic pain relief

https://www.nih.gov/news-events/nih-research-matters/non-opioid-compound-chronic-pain-relief

Neutralizing noroviruses

https://www.nih.gov/news-events/nih-research-matters/neutralizing-noroviruses

23andMe’s bankruptcy doesn’t diminish its impact The genetic testing service launched a cultural transformation in health care

https://www.statnews.com/2025/03/25/23andme-bankruptcy-patient-empowerment-consumer-genetic-testing/

Wave to submit Duchenne drug for approval after Phase 2 success Company says the treatment appears to improve muscle health

https://www.statnews.com/2025/03/26/wave-life-sciences-duchenne-muscular-dystrophy/

Quit Smoking | Metastatic Prostate Cancer | Kidney Cancer, 03/26/2025

https://content.govdelivery.com/accounts/USNIHNCI/bulletins/3d89a6d?reqfrom=share

‘I am going through hell’: Job loss, mental health, and the fate of federal workers

https://www.news-medical.net/news/20250326/e28098I-am-going-through-helle28099-Job-loss-mental-health-and-the-fate-of-federal-workers.aspx

Early work start times linked to discomfort with seasonal time changes

https://www.news-medical.net/news/20250326/Early-work-start-times-linked-to-discomfort-with-seasonal-time-changes.aspx

City of Hope researchers uncover the two-step process of tumor formation

https://www.news-medical.net/news/20250326/City-of-Hope-researchers-uncover-the-two-step-process-of-tumor-formation.aspx

Research unveils cost disparities and information challenges faced by fertility patients in the UK

https://www.news-medical.net/news/20250326/Research-unveils-cost-disparities-and-information-challenges-faced-by-fertility-patients-in-the-UK.aspx

Hair loss? Gut health issues? Dr. Nicole Saphier reveals smart fixes Dr. Nicole Saphier discusses two key health issues facing many Americans By Khloe Quill Fox News Published March 24, 2025 5:20pm EDT

Hair loss? Gut health issues? Dr. Nicole Saphier reveals smart fixes Dr. Nicole Saphier discusses two key health issues facing many Americans By Khloe Quill Fox News Published March 24, 2025 5:20pm EDT https://www.foxnews.com/health/hair-loss-gut-health-issues-dr-nicole-saphier-fixes

Dengue fever cases rising in popular spring break locations, CDC alerts Amid spring break, transmission ‘remains high’ among U.S. travelers Angelica Stabile By Angelica Stabile Fox News Published March 24, 2025 1:33pm EDT

Dengue fever cases rising in popular spring break locations, CDC alerts Amid spring break, transmission ‘remains high’ among U.S. travelers Angelica Stabile By Angelica Stabile Fox News Published March 24, 2025 1:33pm EDT https://www.foxnews.com/health/dengue-fever-cases-rising-popular-spring-break-locations-cdc-alerts

Men face higher cancer risk with this specific body fat measurement The same factor wasn’t linked to a higher risk in women, researchers found Melissa Rudy By Melissa Rudy Fox News Published March 25, 2025 5:00am EDT

Men face higher cancer risk with this specific body fat measurement The same factor wasn’t linked to a higher risk in women, researchers found Melissa Rudy By Melissa Rudy Fox News Published March 25, 2025 5:00am EDT https://www.foxnews.com/health/men-face-higher-cancer-risk-specific-body-fat-measurement

Heart disease risk higher for women who have these unhealthy lifestyle habits Impact was not as high for men with the same habits, study found Melissa Rudy By Melissa Rudy Fox News Published March 25, 2025 3:15pm EDT

Heart disease risk higher for women who have these unhealthy lifestyle habits Impact was not as high for men with the same habits, study found Melissa Rudy By Melissa Rudy Fox News Published March 25, 2025 3:15pm EDT https://www.foxnews.com/health/heart-disease-risk-higher-women-have-unhealthy-lifestyle-habits

First confirmed case of measles in Washington, D.C. investigated by health officials Those with measles are contagious four days before a rash appears and up to four days after Jasmine Baehr By Jasmine Baehr Fox News Published March 25, 2025 6:39pm EDT

First confirmed case of measles in Washington, D.C. investigated by health officials Those with measles are contagious four days before a rash appears and up to four days after Jasmine Baehr By Jasmine Baehr Fox News Published March 25, 2025 6:39pm EDT https://www.foxnews.com/health/first-confirmed-case-measles-washington-d-c-investigated-health-officials

Zenocutuzumab Approved to Treat Lung and Pancreatic Cancers with Rare Genetic Change

https://www.cancer.gov/news-events/cancer-currents-blog/2025/fda-zenocutuzumab-lung-and-pancreatic-cancers-nrg1-alteration?cid=eb_govdel

How strong is the link between red meat and cancer? New study to put the evidence to the test

https://www.news-medical.net/news/20250318/How-strong-is-the-link-between-red-meat-and-cancer-New-study-to-put-the-evidence-to-the-test.aspx?utm_source=news_medical_newsletter&utm_medium=email&utm_campaign=breast_cancer_newsletter_24_march_2025

White wine vs. red wine: Which poses a greater cancer risk?

https://www.news-medical.net/news/20250316/White-wine-vs-red-wine-Which-poses-a-greater-cancer-risk.aspx?utm_source=news_medical_newsletter&utm_medium=email&utm_campaign=breast_cancer_newsletter_24_march_2025

Changes to the Standards of Care in Diabetes—2025

https://www.niddk.nih.gov/health-information/professionals/diabetes-discoveries-practice/changes-standards-care-diabetes2025?utm_medium=niddk+e-mail&utm_source=Diabetes%20Discoveries%20%26%20Practice%20Blog

Mathematical Models Can Help Us Understand — and Possibly Treat — Complex Diseases March 26, 2025 By: Leroy Jia and Xinyi Liu

https://www.nist.gov/blogs/taking-measure/mathematical-models-can-help-us-understand-and-possibly-treat-complex-diseases

FDA approves cabozantinib for adults and pediatric patients 12 years of age and older with pNET and epNET

https://www.fda.gov/drugs/resources-information-approved-drugs/fda-approves-cabozantinib-adults-and-pediatric-patients-12-years-age-and-older-pnet-and-epnet?utm_medium=email&utm_source=govdelivery

martes, 25 de marzo de 2025

Viewpoint: Trump’s tariffs are squeezing American farmers Blake Hurst | Wall Street Journal | March 25, 2025

https://geneticliteracyproject.org/2025/03/25/viewpoint-trumps-tariffs-are-squeezing-american-farmers/?mc_cid=00e34572a6&mc_eid=b73600b7ac

With 23andMe’s bankruptcy, questions emerge about the the private genetic data of its 6.9 million customers March 25, 2025

https://geneticliteracyproject.org/2025/03/25/with-23andmes-bankruptcy-questions-emerge-about-the-the-private-genetic-data-of-its-6-9-million-customers/?mc_cid=00e34572a6&mc_eid=b73600b7ac

Viewpoint: Anatomy of the activist environmental group-tort lawyer alliance—latest target is a safe chemical in use for half a millennium Hank Campbell | Science 2.0 | March 25, 2025

https://geneticliteracyproject.org/2025/03/25/viewpoint-anatomy-of-the-activist-environmental-group-tort-lawyer-alliance-latest-target-is-a-safe-chemical-in-use-for-half-a-millennium/?mc_cid=00e34572a6&mc_eid=b73600b7ac

How did humans get so brainy? Advanced intelligence likely came from a lineage that split off for more than a millenium and then reconnected Kristina Killgrove | Live Science | March 25, 2025

https://geneticliteracyproject.org/2025/03/25/how-did-humans-get-so-brainy-advanced-intelligence-likely-came-from-a-lineage-that-split-off-for-more-than-a-millenium-and-then-reconnected/?mc_cid=00e34572a6&mc_eid=b73600b7ac

Viewpoint: Weaponizing ‘informed consent’ — Here is how Robert F. Kennedy, Jr. is undermining support for vaccinations … and it’s going to get a lost worse David Gorski | Science Based Medicine | March 25, 2025

https://geneticliteracyproject.org/2025/03/25/viewpoint-weaponizing-informed-consent-here-is-how-robert-f-kennedy-jr-is-undermining-support-for-vaccinations-and-its-going-to-get-a-lost-worse/?mc_cid=00e34572a6&mc_eid=b73600b7ac

Defining healthy: Three uniquely effective ways to measure your health — and what it has to do with food Lucy Stitzer | March 25, 2025

https://geneticliteracyproject.org/2025/03/25/defining-healthy-three-uniquely-effective-ways-to-measure-your-health-and-what-it-has-to-do-with-food/?mc_cid=00e34572a6&mc_eid=b73600b7ac

Engaging More Men in Cancer Prevention Research

Advancing Precision Cancer Medicine: Unveiling the Future Frontier Authors: Elena Garralda, MD, PhD; Atish D. Choudhury, MD, PhD; Jarushka Naidoo, MB, BCH, MHS; Umberto Malapelle, PhD

https://www.medscape.org/viewarticle/advancing-precision-cancer-medicine-unveiling-future-2025a10000dr/1

TACE-Based Treatment Combinations Effective Against Intermediate-Stage Liver Cancer

https://www.cancer.gov/news-events/cancer-currents-blog/2025/liver-cancer-tace-plus-targeted-and-immunotherapy?cid=eb_govdel

FDA Approves First Treatment for C3 Glomerulopathy

Mar 25, 2025| Autoimmune / Autoinflammatory Disorders, Kidney And Urinary Diseases, Regulations, Treatment FDA Approves First Treatment for C3 Glomerulopathy The U.S. Food and Drug Administration has approved… https://checkrare.com/

Improved Growth in Children Suffering from Fabry Disease Treated With Agalsidase Beta By: Madaline Spencer| Published on: Mar 11, 2025 +++

Improved Growth in Children Suffering from Fabry Disease Treated With Agalsidase Beta By: Madaline Spencer| Published on: Mar 11, 2025 https://checkrare.com/improved-growth-in-children-suffering-from-fabry-disease-treated-with-agalsidase-beta/ Treatment Comparisons for Left Ventricular Mass Index in Fabry Disease By: Madaline Spencer| Published on: Mar 10, 2025 https://checkrare.com/treatment-comparisons-for-left-ventricular-mass-index-in-fabry-disease/ Five-Year Study Results in Patients With Fabry Disease By: Madaline Spencer| Published on: Feb 26, 2025 https://checkrare.com/five-year-study-results-in-patients-with-fabry-disease/

Results From the Phase 3 Vivacity-MG3 Study in Myasthenia Gravis By: Scott Harwood| Published on: Mar 3, 2025

https://checkrare.com/results-from-the-phase-3-vivacity-mg3-study-in-myasthenia-gravis/

Caplacizumab Combination Therapy in Patients With Acquired Thrombotic Thrombocytopenic Purpura By: Madaline Spencer|

https://checkrare.com/caplacizumab-combination-therapy-in-patients-with-acquired-thrombotic-thrombocytopenic-purpura/

FDA Approval of Setmelanotide for Patients 2 Years and Older With MC4R Pathway Diseases By: Madaline Spencer|

https://checkrare.com/fda-approval-of-setmelanotide-for-patients-2-years-and-older-with-mc4r-pathway-diseases/

FDA Approves First Treatment for Macular Telangiectasia Type 2 By: Madaline Spencer| Published on: Mar 13, 2025

https://checkrare.com/fda-approves-first-treatment-for-macular-telangiectasia-type-2/

2025 Orphan Drugs: PDUFA Dates and FDA Approvals By: Peter Ciszewski|

https://checkrare.com/2025-orphan-drugs-pdufa-dates-and-fda-approvals/

Restless Legs Syndrome Treatment and Guidelines Update By: CheckRare Staff|

https://checkrare.com/restless-legs-syndrome-treatment-and-guidelines-update/

Watch the DAYBUE® (trofinetide) in Practice Video Series to Hear Expert Insights on the First Treatment for This Rare Disease By: CheckRare Staff | Updated on: Jan 28, 2025

https://checkrare.com/watch-the-daybue-trofinetide-in-practice-video-series-to-hear-expert-insights/ Rett syndrome thought leaders discuss how DAYBUE® (trofinetide), the first and only FDA-approved treatment for Rett syndrome in adults and pediatric patients 2 years of age and older, plays a role in their patients’ treatment plans, while shedding light on their personal experiences with DAYBUE in their practices.[1,2] Watch the entire DAYBUE in Practice video series below to learn about the DAYBUE clinical trial results, gastrointestinal (GI) management strategies, and how DAYBUE plays an important role in comprehensive Rett syndrome care.

Optimizing Therapeutic Proteins Through PEGylation: Key Parameters and Impacts Professors João Gonçalves and Paolo Caliceti

https://checkrare.com/optimizing-therapeutic-proteins-through-pegylation/

Improving Health Equity in Hereditary Angioedema (HAE): A Panel Discussion Aleena Banerji, MD, Timothy Craig, DO, Marc Riedl, MD

https://checkrare.com/improving-health-equity-in-hereditary-angioedema-hae-a-panel-discussion/ Hereditary angioedema (HAE) is a rare genetic disease that results in immunologic attacks that can be life-threatening. HAE is the result of reduced levels of C1-inhibitor, a protein involved in various physiological processes in plasma, most notably with the complement system. This panel discussion by three clinical research leaders in HAE, Drs. Aleena Banerji, Timothy Craig, and Marc Riedl, provide an overview of the discrepancies in care observed in certain patient populations, as well as a discussion on best practices to reduce those inequalities moving forward.

lunes, 24 de marzo de 2025

Obesity most prevalent in these 3 southern cities New report analyzes food intake, fitness and health consequences Angelica Stabile By Angelica Stabile Fox News Published March 20, 2025 4:15pm EDT

Obesity most prevalent in these 3 southern cities New report analyzes food intake, fitness and health consequences Angelica Stabile By Angelica Stabile Fox News Published March 20, 2025 4:15pm EDT https://www.foxnews.com/health/obesity-most-prevalent-3-southern-cities

Diabetes risk lowered by eating one surprisingly sweet food, study suggests Tropical fruit could support more balanced blood sugar levels, researchers say By Khloe Quill Fox News Published March 20, 2025 1:50pm EDT

Diabetes risk lowered by eating one surprisingly sweet food, study suggests Tropical fruit could support more balanced blood sugar levels, researchers say By Khloe Quill Fox News Published March 20, 2025 1:50pm EDT https://www.foxnews.com/health/diabetes-risk-lowered-eating-surprisingly-sweet-food-study-shows

Parkinson’s cases could double globally by 2050, study reveals Neurodegenerative diseases predicted to surpass cancer as second leading cause of death worldwide by 2040 By Khloe Quill Fox News Published March 21, 2025 11:38am EDT

Parkinson’s cases could double globally by 2050, study reveals Neurodegenerative diseases predicted to surpass cancer as second leading cause of death worldwide by 2040 By Khloe Quill Fox News Published March 21, 2025 11:38am EDT https://www.foxnews.com/health/parkinsons-cases-could-double-globally-2050-study-reveals

Kids with Down syndrome can live 'abundant lives,' dad tells Fox News contributor Fox News contributor Tom Shillue speaks to the dad of a child with Down syndrome on World Down Syndrome Day Melissa Rudy By Melissa Rudy , Angelica Stabile Fox News Published March 21, 2025 2:43pm EDT

Kids with Down syndrome can live 'abundant lives,' dad tells Fox News contributor Fox News contributor Tom Shillue speaks to the dad of a child with Down syndrome on World Down Syndrome Day Melissa Rudy By Melissa Rudy , Angelica Stabile Fox News Published March 21, 2025 2:43pm EDT https://www.foxnews.com/health/kids-down-syndrome-can-live-abundant-lives-dad-tells-fox-news-contributor

Alzheimer’s-related dementia could be prevented by experimental drug, researchers say Medication is designed to reduce amyloid in the brain, a hallmark of Alzheimer’s Melissa Rudy By Melissa Rudy Fox News Published March 22, 2025 5:00am EDTAlzheimer’s-related dementia could be prevented by experimental drug, researchers say Medication is designed to reduce amyloid in the brain, a hallmark of Alzheimer’s Melissa Rudy By Melissa Rudy Fox News Published March 22, 2025 5:00am EDT

Alzheimer’s-related dementia could be prevented by experimental drug, researchers say Medication is designed to reduce amyloid in the brain, a hallmark of Alzheimer’s Melissa Rudy By Melissa Rudy Fox News Published March 22, 2025 5:00am EDT https://www.foxnews.com/health/alzheimers-related-dementia-could-prevented-experimental-drug-researchers-say

Parents of girl who died after measles infection said they wouldn't get MMR vaccine West Texas couple told Children’s Health Defense their daughter also had pneumonia Melissa Rudy By Melissa Rudy Fox News Published March 22, 2025 1:41pm EDT

Parents of girl who died after measles infection said they wouldn't get MMR vaccine West Texas couple told Children’s Health Defense their daughter also had pneumonia Melissa Rudy By Melissa Rudy Fox News Published March 22, 2025 1:41pm EDT https://www.foxnews.com/health/parents-girl-died-measles-infection-wouldnt-get-mmr-vaccine

Prostate cancer risk increases by 45% among men who share one troubling behavior New health study highlights importance of medical screening Melissa Rudy By Melissa Rudy Fox News Published March 22, 2025 3:53pm EDT

Prostate cancer risk increases by 45% among men who share one troubling behavior New health study highlights importance of medical screening Melissa Rudy By Melissa Rudy Fox News Published March 22, 2025 3:53pm EDT https://www.foxnews.com/health/prostate-cancer-risk-increases-45-among-men-share-behavior

Tennessee reports first measles case amid U.S. outbreak According to the Tennessee Department of Health, the Volunteer State has recorded its first case of measles this year amid a nationwide outbreak Peter D'Abrosca By Peter D'Abrosca Fox News Published March 23, 2025 5:29pm EDT

Tennessee reports first measles case amid U.S. outbreak According to the Tennessee Department of Health, the Volunteer State has recorded its first case of measles this year amid a nationwide outbreak Peter D'Abrosca By Peter D'Abrosca Fox News Published March 23, 2025 5:29pm EDT https://www.foxnews.com/health/tennessee-reports-first-measles-case-amid-u-s-outbreak

Diabetes breakthrough: Chinese trial paves way for insulin-free future In a groundbreaking treatment, insulin-producing cells sourced from a young woman's own body were successfully implanted, effectively eliminating the need for daily injections Daniel Khaykelson/Davidson Institute of Science|Yesterday | 18:11

Diabetes breakthrough: Chinese trial paves way for insulin-free future In a groundbreaking treatment, insulin-producing cells sourced from a young woman's own body were successfully implanted, effectively eliminating the need for daily injections Daniel Khaykelson/Davidson Institute of Science|Yesterday | 18:11 https://www.ynetnews.com/health_science/article/bkn8jp62je

‘Out of breaking points comes opportunity’: Israel maps mental health tech boom After October 7, Israel sees a mental health tech boom: 117 startups tackling trauma, resilience with AI, self-care and automation; Collaboration, funding and policy changes are crucial to accelerate healing, say experts Maayan Hoffman/The Media Line|07:27

‘Out of breaking points comes opportunity’: Israel maps mental health tech boom After October 7, Israel sees a mental health tech boom: 117 startups tackling trauma, resilience with AI, self-care and automation; Collaboration, funding and policy changes are crucial to accelerate healing, say experts Maayan Hoffman/The Media Line|07:27 https://www.ynetnews.com/health_science/article/sy00ndian1x

Ultra-processed foods lead to chronic diseases? Bread, breakfast cereals, yogurt and dairy desserts are all associated with a lower risk of cardiovascular disease and diabetes Carrie Dennett | Seattle Times | March 24, 2025

https://geneticliteracyproject.org/2025/03/24/ultra-processed-foods-lead-to-chronic-diseases-bread-breakfast-cereals-yogurt-and-dairy-desserts-are-all-associated-with-a-lower-risk-of-cardiovascular-disease-and-diabetes/

While raw milk increases health risk by 70,000% percent, cheese made from raw milk is safe to eat Hank Campbell | Science 2.0 | March 24, 2025

https://geneticliteracyproject.org/2025/03/24/while-raw-milk-increases-health-risk-by-70000-percent-cheese-made-from-raw-milk-is-safe-to-eat/

RFK, Jr. calls the HPV vaccine ‘dangerous and defective’. He’s made millions of dollars litigating this falsehood Lisa Doggett | NPR | March 21, 2025

https://geneticliteracyproject.org/2025/03/21/rfk-jr-calls-the-hpv-vaccine-dangerous-and-defective-hes-made-millions-of-dollars-litigating-this-falsehood/

Sociogenomics—How our environment molds genes and shapes our Noopur Choksi | New York Times | March 24, 2025

https://geneticliteracyproject.org/2025/03/24/sociogenomics-how-our-environment-molds-genes-in-influencing-what-we-become/

Vaccines for cancers? It’s coming, and we’ll have COVID response-spurred mRNA vaccines to thank Lennard Lee | Wired | March 24, 2025

https://geneticliteracyproject.org/2025/03/24/vaccines-for-cancers-its-coming-and-well-have-covid-response-spurred-mrna-vaccines-to-thank/

Viewpoint: Here’s a reminder of what life was like in RFK Jr’s.’ ‘good ol’ pre-vaccine days Elena Conis | New York Times | March 24, 2025

https://geneticliteracyproject.org/2025/03/24/viewpoint-heres-a-reminder-of-what-life-was-like-in-rfk-jrs-good-ol-pre-vaccine-days/

Viewpoint: Health officials and the media largely got it wrong—Once widely derided Covid lab leak theory now seems the likeliest explanation for the orgins of the pandemic Zeynep Tufekci | New York Times | March 21, 2025

https://geneticliteracyproject.org/2025/03/21/viewpoint-health-officials-and-the-media-largely-got-it-wrong-once-widely-derided-covid-lab-leak-theory-now-seems-the-likeliest-explanation-for-the-orgins-of-the-pandemic/

Push for transparency in research: Corporations and academic institutions under pressure to advance public disclosure Peter Phillips | March 21, 2025

https://geneticliteracyproject.org/2025/03/21/push-for-transparency-in-research-corporations-and-academic-institutions-under-pressure-to-advance-public-disclosure/

Viewpoint: PFAS disinformation—How extremist environmentalists have demonized an entire class of safe-as-used properly chemicals Susan Goldhaber | March 24, 2025

https://geneticliteracyproject.org/2025/03/24/viewpoint-pfas-disinformation-how-extremist-environmentalists-have-demonized-an-entire-class-of-safe-as-used-properly-chemicals/

GLP Spaces on X: Deadly Thin Mints? $5 million chemical tort scam targets Girl Scout cookies Cameron English, Jon Entine, Liza Dunn | March 24, 2025

https://geneticliteracyproject.org/2025/03/24/glp-spaces-on-x-deadly-thin-mints-5-million-chemical-tort-scam-targets-girl-scout-cookies/

domingo, 23 de marzo de 2025

Experience of illness with chronic singultus: a qualitative interview study

https://ojrd.biomedcentral.com/?utm_source=bmc_etoc&utm_medium=email&utm_campaign=CONR_13023_AWA1_GL_DTEC_054CI_TOC-250323

Acute Myeloid Leukemia Treatment (PDQ®)–Health Professional Version

https://www.cancer.gov/types/leukemia/hp/adult-aml-treatment-pdq?cid=eb_govdel#top

Breast Cancer Treatment (PDQ®)–Health Professional Version

https://www.cancer.gov/types/breast/hp/breast-treatment-pdq?cid=eb_govdel#top

Chronic Myeloid Leukemia Treatment (PDQ®)–Health Professional Version

https://www.cancer.gov/types/leukemia/hp/cml-treatment-pdq?cid=eb_govdel#top

Peripheral T-Cell Non-Hodgkin Lymphoma Treatment (PDQ®)–Health Professional Version

https://www.cancer.gov/types/lymphoma/hp/peripheral-t-cell-lymphoma-pdq?cid=eb_govdel#top

Cardiology & Vascular Medicine: Safety and efficacy of long-term gantenerumab treatment in dominantly inherited Alzheimer's disease: an open-label extension of the phase 2/3 multicentre, randomised, double-blind, placebo-controlled platform DIAN-TU trial

https://www.thelancet.com/collections/cardiology-vascular-medicine?parent=001536

Allergy & Immunology: The burden of β-lactam allergy labels in health care: a systematic review and meta-analysis

https://www.thelancet.com/collections/allergy-immunology?parent=001534

Safety and drug quantification of the dapivirine vaginal ring and oral pre-exposure prophylaxis in breastfeeding mother–infant pairs (MTN-043): a phase 3B, open-label, randomised trial

https://www.thelancet.com/journals/lanhiv/article/PIIS2352-3018(24)00306-0/abstract?utm_campaign=infocusalerts-obgyn&utm_medium=email&dgcid=hubspot_email_infocusalerts-obgyn_feature&_hsenc=p2ANqtz--9mJIhIFRWRZa3lTaSqZwLQl-pMaY02tlbc33VFHP3vS6yjNMuhNwlr6kQPV4MtgKQTDGGmQNLYmDhuvgYvNr5VXvJsw&_hsmi=352424484&utm_content=352424484&utm_source=hs_email

Accelerating action for gender equality in health The Lancet Digital Health

https://www.thelancet.com/journals/landig/issue/vol7no3/PIIS2589-7500(25)X0003-0

Screening performance and characteristics of breast cancer detected in the Mammography Screening with Artificial Intelligence trial (MASAI): a randomised, controlled, parallel-group, non-inferiority, single-blinded, screening accuracy study

https://www.thelancet.com/journals/landig/article/PIIS2589-7500(24)00267-X/fulltext?dgcid=hubspot_email_infocusalerts-obgyn_feature&utm_campaign=infocusalerts-obgyn&utm_medium=email&_hsenc=p2ANqtz-9I4iahU6uuU6RUrNe0MgXiTcpf4BJK80_9wSPP1LpFHG9yWoqiycKfwHYPSXOelcvLUs9HB0vDc4JkKvQ2GY9LCn54lw&_hsmi=352424484&utm_content=352424484&utm_source=hs_email

Phages return CRISPR to its microbial roots Virus-inspired delivery methods enable gene editing of dysregulated microbes.

https://www.drugdiscoverynews.com/phages-return-crispr-to-its-microbial-roots-16270?utm_campaign=DDN_Newsletter_Science%20Spotlight&utm_medium=email&_hsenc=p2ANqtz--Ine9fki8ZJVcpqseTJRxqdzf5AQbPnjToji7c81wGGTlJ8cenvdbi7wppmkMIWkdM1f5oaFdp9Z5wWzpUhhuRVE5ydw&_hsmi=353108708&utm_content=353040035&utm_source=hs_email

Weekly Rundown: Scientists told to remove mRNA tech from grants From advances in graft versus host disease treatment to updates on H5N1 and Duchenne muscular dystrophy research, the DDN editors break down the news this week.

https://www.drugdiscoverynews.com/weekly-rundown-scientists-told-to-remove-mrna-tech-from-grants-16273

Helping parents fight their children’s eating disorders An AI app founded by the parent of a child with anorexia helps families navigate treatment plans for the growing number of children with eating disorders.Helping parents fight their children’s eating disorders An AI app founded by the parent of a child with anorexia helps families navigate treatment plans for the growing number of children with eating disorders.

https://www.israel21c.org/helping-parents-fight-their-childrens-eating-disorders/

Gene editing may be key to treating head and neck cancers CRISPR technique can target single genes essential for cancer cell survival, toppling the whole structure, says nanomedicine researcher.

https://www.israel21c.org/gene-editing-may-be-key-to-treating-head-and-neck-cancers/

UP IN SMOKE: THE IMPACT OF WILDFIRES ON LITTLE LUNGS

Up In Smoke: The Impact of Wildfires on Little Lungs By Ivanhoe Broadcast News on March 29, 2025 https://www.ivanhoe.com/?p=35200&preview=1&_ppp=8f05e4d928

REFRIGERATOR RULES: WHAT TURNS TOXIC AND WHAT WON’T?

Refrigerator Rules: What Turns Toxic And What Won’t? By Ivanhoe Broadcast News on March 28, 2025 https://www.ivanhoe.com/?p=35220&preview=1&_ppp=4ec4ab5ded

HUMAN HACKING: WHEN CYBER CRIMINALS TARGET YOU

Human Hacking: When Cyber Criminals Target You By Ivanhoe Broadcast News on March 27, 2025 https://www.ivanhoe.com/?p=35217&preview=1&_ppp=866df7974b

SWEET DECEPTION: SNEAKY PLACES SUGAR HIDES

Sweet Deception: Sneaky Places Sugar Hides By Ivanhoe Broadcast News on March 26, 2025 https://www.ivanhoe.com/?p=35214&preview=1&_ppp=51962c418f

FIVE STARS OR FAKE: SPOTTING DECEPTIVE ONLINE REVIEWS

Five Stars Or Fake: Spotting Deceptive Online Reviews By Ivanhoe Broadcast News on March 25, 2025 https://www.ivanhoe.com/?p=35211&preview=1&_ppp=a17eeba00c

IT’S A SPRING THING: CLEAN UP YOUR LIFE TO LIVE LONGER

It’s A Spring Thing: Clean Up Your Life To Live Longer By Ivanhoe Broadcast News on March 24, 2025 https://www.ivanhoe.com/?p=35208&preview=1&_ppp=c464d723da

sábado, 22 de marzo de 2025

Melatonin vs. Magnesium: Which Works Best for Sleep?

https://www.news-medical.net/health/Melatonin-vs-Magnesium-Which-Works-Best-for-Sleep.aspx

New drug combination shows promise in treating melanoma brain metastasis

https://www.news-medical.net/news/20250321/New-drug-combination-shows-promise-in-treating-melanoma-brain-metastasis.aspx

Study reveals how virtual body pain disrupts sense of ownership

https://www.news-medical.net/news/20250321/Study-reveals-how-virtual-body-pain-disrupts-sense-of-ownership.aspx

Groundbreaking study unveils key mechanism for neuronal identity regulation

https://www.news-medical.net/news/20250322/Groundbreaking-study-unveils-key-mechanism-for-neuronal-identity-regulation.aspx

New video-based method enhances detection of infantile spasms syndrome

https://www.news-medical.net/news/20250321/New-video-based-method-enhances-detection-of-infantile-spasms-syndrome.aspx

The forgotten social and emotional toll of rare diseases

https://www.re-solveglobalhealth.com/post/the-forgotten-social-and-emotional-toll-of-rare-diseases

Rare Diseases: Betting on the pharma package for timely and equitable access, still awaiting an EU Action Plan

https://www.euractiv.com/section/health-consumers/news/rare-diseases-betting-on-the-pharma-package-for-timely-and-equitable-access-still-awaiting-an-eu-action-plan/ In this recent Euractiv article, Valentina Bottarelli, our Head of Policy and Public Affairs, called for a European Action Plan for Rare Diseases to unify existing efforts and create a coherent strategy that ensures health equity, faster diagnoses, and better access to treatments. She also elaborated on the ongoing reforms to the EU's pharmaceutical legislation and their centrality to strengthening patient engagement, securing medicine supply, and fostering innovation.

Podcast: Rare on Air

https://www.eurordis.org/rare-on-air/ Rare on Air Stories Don't forget to listen to our bonus podcast series marking Rare Disease Day! Hosted by Julien Poulain, the Rare on Air Stories series presents the striking personal stories of individuals living with a rare disease across the globe. From Australia to Mexico, Nepal to Nigeria and the U.S. to the U.K., each episode shares deeply moving personal experiences. Listen now to our latest episode, where we follow the journey of Noah from the United States! Listen to the podcast by subscribing to Spotify, Apple Podcasts, Amazon Music, or YouTube.

39th Workshop of the EURORDIS Round Table of Companies (ERTC): Addressing systemic inequalities through patient-driven innovation & research

https://www.eurordis.org/39th-ertc/ ERTC Workshop Last month, our 39th EURORDIS Round Table of Companies (ERTC) Workshop in Brussels focused on patient-driven innovation to address systemic health inequalities. The workshop focused on integrating patients' priorities into future EU research policies and funding. The discussions explored the need to enhance clinical trials, leveraging public-private investments, corroborating healthcare systems, and promoting fairness in newborn screening.

EURORDIS Membership Meeting (EMM) 2025 March 2025

https://www.eurordis.org/eurordis-membership-meeting-emm-2025/ This year’s EURORDIS Membership Meeting will be held in Riga, Latvia, on 22-24 May. This event represents an invaluable opportunity for the members of the rare disease community to meet while sharing knowledge and building partnerships. Participants will explore topics such as advocacy at national and EU levels, volunteer involvement in healthcare, and leveraging Rare Barometer findings for advocacy. https://www.eurordis.org/rare-barometer/english/

SANT launches public consultation on rare diseases

https://www.europarl.europa.eu/news/en/press-room/20250227IPR27074/sant-launches-public-consultation-on-rare-diseases The European Parliament Committee on Public Health (SANT) has opened a public Consultation on Rare Diseases to identify the challenges faced by those living with a rare disease and the potential EU actions to address them. With SANT now a fully-fledged parliamentary committee, the consultation presents a key moment to advocate for better funding, cooperation, and recognition of our community's unmet needs. EURORDIS' response highlights policy priorities, and you can submit your own response by 31 March! For questions or feedback, contact valentina.bottarelli@eurordis.org. Have your say: Help shape the future of rare disease policy in Europe The European Parliament’s Committee on Public Health (SANT), newly established as a fully-fledged committee, is responsible for shaping EU policies on healthcare, pharmaceutical legislation, and public health. It has now launched a Consultation on Rare Diseases, seeking input from patients, caregivers, researchers, healthcare professionals, and organisations working in the field. https://www.eurordis.org/publications/eurordis-submission-sant-consultation/

Decreasing the invasiveness of deep brain stimulation

Decreasing the invasiveness of deep brain stimulation: Researchers are developing a preclinical method to stimulate the brain without drilling into the skull by guiding a catheter through the cerebrospinal fluid. Deep brain stimulation—the application of electricity to specific deep brain regions to modulate their function—has been used clinically for over 25 years. This technique is used to monitor and treat neurological conditions, especially movement disorders, such as Parkinson’s disease and epilepsy. Yet many of these interfaces are highly invasive, as they require removing part of the skull to implant electrodes in the brain. Finding a way to monitor and stimulate the central nervous system in a less intrusive way has been a holy grail for those in the neuromodulation field. Now, a collaborative team of NIH-funded researchers at Rice University and The University of Texas are developing a method to access and stimulate deep brain regions without drilling into the skull. They engineered a tiny pulse generator that can be implanted in the spine following a lumbar puncture. This pulse generator is connected to a stimulating catheter, which can be guided through the cerebrospinal fluid to the surface of the brain. After preliminary experiments in human cadavers, the team successfully used the device to record and stimulate brain activity in sheep with the aid of a wireless interface. Their work was recently published in Nature Biomedical Engineering.

Seasonal Allergies at a Glance

https://www.nccih.nih.gov/health/seasonal-allergies-at-a-glance?nav=govd As spring approaches, seasonal allergic rhinitis—also called hay fever—becomes a problem for some people. Symptoms may include sneezing, coughing, a runny or stuffy nose, and itching in the eyes, nose, mouth, and throat. Many complementary health approaches have been studied for allergic rhinitis, and there’s evidence that a few may help. Rinsing the sinuses with a neti pot (a device that comes from the Ayurvedic tradition) or other devices may be a useful addition to conventional treatment for seasonal allergies. Make sure to use only distilled, sterile, or boiled and cooled water; tap water may not be safe for use as a nasal rinse. There’s evidence that acupuncture may be helpful for seasonal allergy symptoms. Some studies of probiotics for allergies have had promising results, but others have not. It’s possible that only some types of probiotics are helpful.

Posttraumatic Stress Disorder Learning Hub: Improving Recognition and Management

https://www.medscape.org/sites/advances/ptsd-learning-hub?sso=true&uac=148436CN&src=mkmcmr_driv_clinad_mscpedu

IMPACT EBC: IMPlementing Advances in Cancer Treatment for Patients With HR+/HER2- Early Breast Cancer Moving Patient Care Forward

https://www.medscape.org/sites/advances/early-breast-cancer?sso=true&uac=148436CN&src=mkmcmr_driv_clinad_mscpedu#ca-section-2

Withdrawal of life sustaining therapies in patients with or without acute brain injury +++

COMMENTS Withdrawal of life sustaining therapies in patients with or without acute brain injury Free with registration https://www.thelancet.com/journals/lanres/article/PIIS2213-2600(25)00008-6/abstract?utm_campaign=conferencealerts&utm_medium=email&dgcid=hubspot_email_conferencealerts_isicem25&_hsenc=p2ANqtz--rQN6km016zetaUjkoDznhldhX3grKw1VNNzDreQ25CnzsSWHhX25e-wN4Twkwf9ejc7mPjv2aGMqaNhhRh3GplxcJMQ&_hsmi=352808851&utm_content=352808851&utm_source=hs_email Preoxygenation for tracheal intubation in adults who are critically ill: time to abandon the facemask? Free with registration https://www.thelancet.com/journals/lanres/article/PIIS2213-2600(25)00056-6/abstract?utm_campaign=conferencealerts&utm_medium=email&dgcid=hubspot_email_conferencealerts_isicem25&_hsenc=p2ANqtz-9FptrEp4QRM1yekX7fB2o1JwzC59KdPyEtMt0qhIDwd-xO3Rb6OKrWDWAkiWNXISUvnyQUyCg7YvGs_NrOzHPb5PDb6Q&_hsmi=352808851&utm_content=352808851&utm_source=hs_email Nasal high-flow oxygen for apnoeic oxygenation during emergency endotracheal intubation of children Free with registration until Mar 29, 2025 https://www.thelancet.com/journals/lanres/article/PIIS2213-2600(25)00085-2/abstract?utm_campaign=conferencealerts&utm_medium=email&dgcid=hubspot_email_conferencealerts_isicem25&_hsenc=p2ANqtz-8ysi4xFSEa7P680VqjRTHyMLr8p9fBZqqTjhXgC9ZiPAH_53o6OX9XPklbv0LTgdritcdmAixx-rG-DpySoqeTCVXycA&_hsmi=352808851&utm_content=352808851&utm_source=hs_email

Effectiveness of nasal high-flow oxygen during apnoea on hypoxaemia and intubation success in paediatric emergency and ICU settings: a randomised, controlled, open-label trial

https://www.thelancet.com/journals/lanres/article/PIIS2213-2600(25)00074-8/abstract?utm_campaign=conferencealerts&utm_medium=email&dgcid=hubspot_email_conferencealerts_isicem25&_hsenc=p2ANqtz-9BvqpDR6w1vAKeZmjDzcorixmAGUr0folT6HThKVikGSuK81ccogy33IlD9UmAuYYzhfZh4gLe7KHWAZvkk44qyTaObQ&_hsmi=352808851&utm_content=352808851&utm_source=hs_email

Preoxygenation strategies for intubation of patients who are critically ill: a systematic review and network meta-analysis of randomised trials

https://www.thelancet.com/journals/lanres/article/PIIS2213-2600(25)00029-3/abstract?utm_campaign=conferencealerts&utm_medium=email&dgcid=hubspot_email_conferencealerts_isicem25&_hsenc=p2ANqtz--aMHhxzEMmhwa4WgcpXr_o714uRJxbe02_r_0Sj1zl6A07W_Pq61pRdLsUQTBeWBIi7BROPO1acTSaI5VqDSjem5ybdA&_hsmi=352808851&utm_content=352808851&utm_source=hs_email

Decisions to withdraw or withhold life-sustaining therapies in patients with and without acute brain injury: a secondary analysis of two prospective cohort studies

https://www.thelancet.com/journals/lanres/article/PIIS2213-2600(24)00404-1/abstract?utm_campaign=conferencealerts&utm_medium=email&dgcid=hubspot_email_conferencealerts_isicem25&_hsenc=p2ANqtz-97FuvpYCVh_SueJbF9im7HoEwZjywyMv_Zk32uiYKyFYfYB6npxVMpyhHoFzXBmgImzxgUKH203xhqt14PddcH5-UCYg&_hsmi=352808851&utm_content=352808851&utm_source=hs_email

NIH researchers develop eye drops that slow vision loss in animals Treatment shows potential to slow the progression of human degenerative eye diseases, including retinitis pigmentosa.

https://www.nih.gov/news-events/news-releases/nih-researchers-develop-eye-drops-slow-vision-loss-animals

viernes, 21 de marzo de 2025

Study reveals gaps in lung cancer screening despite updated guidelines

https://www.news-medical.net/news/20250320/Study-reveals-gaps-in-lung-cancer-screening-despite-updated-guidelines.aspx

Natural compounds identified as potential inhibitors of SARS-CoV-2 spike protein

https://www.news-medical.net/news/20250320/Natural-compounds-identified-as-potential-inhibitors-of-SARS-CoV-2-spike-protein.aspx

Endometriosis Breakthroughs: New Treatments and Research

https://www.news-medical.net/health/Endometriosis-Breakthroughs-New-Treatments-and-Research.aspx

Researchers dig deep into cancer with magnetic nanoparticles Science Highlights March 21, 2025

https://www.nibib.nih.gov/news-events/newsroom/researchers-dig-deep-cancer-magnetic-nanoparticles

Intensive Program Helps People Being Screened for Lung Cancer Quit Smoking

https://www.cancer.gov/news-events/cancer-currents-blog/2025/lung-cancer-screening-helping-people-quit-smoking?cid=eb_govdel

Precision T-Cell Therapy Improves Blood Cancer Outcomes Edited by Susan Ruel, PhD March 21, 2025 +++++

Precision T-Cell Therapy Improves Blood Cancer Outcomes Edited by Susan Ruel, PhD March 21, 2025 https://www.medscape.com/viewarticle/precision-t-cell-therapy-improves-blood-cancer-outcomes-2025a10006rv 3D Total Body Photography Shown to Decrease Biopsies, Improve Dx of Nonmelanoma Skin Cancers Richard Mark Kirkner March 21, 2025 https://www.medscape.com/viewarticle/3d-total-body-photography-shown-decrease-biopsies-improve-dx-2025a10006r7 CA-125 Shows Less Accuracy in Black and American Indian Patients with Ovarian Cancer Edited by Katie Lennon March 21, 2025 https://www.medscape.com/viewarticle/ca-125-shows-less-accuracy-black-and-american-indian-2025a10006rk Do Patients With Intermediate-Risk Cervical Cancer Need Adjuvant Chemotherapy? Whitney McKnight March 20, 2025 https://www.medscape.com/viewarticle/do-patients-intermediate-risk-cervical-cancer-need-adjuvant-2025a10006q4 Can Adjuvant Immunotherapy Boost Survival Outcomes in Advanced Nasopharyngeal Cancer? Edited by Gargi Mukherjee March 20, 2025 https://www.medscape.com/viewarticle/can-adjuvant-immunotherapy-boost-survival-outcomes-advanced-2025a10006o6

OK to Skip Pelvic Lymph Node Dissection in Cervical Cancer? Megan Brooks March 21, 2025

https://www.medscape.com/viewarticle/ok-skip-pelvic-lymph-node-dissection-cervical-cancer-2025a10006s3

Projected Cancer Trends Highlight Urgent Need for Prevention Maurie Markman, MD

https://www.medscape.com/viewarticle/projected-cancer-trends-highlight-urgent-need-prevention-2025a10005lr

Encapsulation of a Single-Stranded Form of DNA Impurities into the Capsid of a Recombinant Adeno-Associated Virus

https://www.liebertpub.com/doi/10.1089/hum.2024.264?utm_campaign=MAL_HUM&utm_medium=email&_hsenc=p2ANqtz-8iXI7dSloS6J_pZvH0Om8Np3gdmU7z_JfPtlgF9Df1-IsCiO8RmrWHSt89dd8QhGuOUGtewNJF1u_wWkpOb2ZtWaNEWA&_hsmi=352880154&utm_content=352880154&utm_source=hs_email Evaluating DNA Impurities in Recombinant Adeno-Associated Virus New Rochelle, NY, March 20, 2025—A new study in the peer-reviewed journal Human Gene Therapy indicates that DNA impurities derived from plasmid and host cell DNA are encapsulated into recombinant adeno-associated virus (rAAV) capsids as single-stranded DNA. Click here to read the article now. rAAVs are widely used viral vectors in human gene therapy, but contamination from DNA impurities, such as plasmid and host cell DNA, remains a significant quality control concern for their manufacture. In this study, Kazuhisa Uchida, from Kobe University, and coauthors examined several purifies rAAV samples and found that they contained DNA derived from three plasmids. They determined that the impurities were encapsulated into the rAAV capsids as single-stranded DNA. The investigators suggest that when rAAVs are used in gene therapy, the adverse effects of the single-stranded form of DNA impurities may differ from those of double-stranded DNA. “It may be necessary to reconsider or evaluate the effects of single-strand form of DNA impurities independently,” stated the investigators. “Studies like this are incredibly important to better understand how DNA impurities are generated and what sources they come from during the production process in order to improve the efficiency of manufacturing and purity of the final rAAV product, which will help make the therapy more effective and reduce adverse events for patients,” says Managing Editor of Human Gene Therapy Thomas Gallagher, PhD, from the University of Massachusetts Chan Medical School.

We empower, partner, and advocate for people living with a rare disease in Europe

https://www.eurordis.org/

Breaking Barriers: Advancing accessibility and inclusion for cerebral palsy in Milan March 2025

https://www.eurordis.org/breaking-barriers-advancing-accessibility-and-inclusion-for-cerebral-palsy-in-milan/

More Than You Can Imagine: A recap of our conference at the European Parliament March 2025

https://www.eurordis.org/recap-conference-european-parliament/

European Parliament Event on Rare Disease Day +++

https://www.eurordis.org/european-parliament-rare-disease-day/ Impactofrarediseases: https://download2.eurordis.org/REPORT_European_Parliament_event_on_RDD.pdf Patient organisations warn against EU rollback on patient involvement in medicines regulation https://www.eurordis.org/epf-eurordis-joint-statement-patient-involvement/

Most Read Papers - Cancer Science & Oncogenesis

https://read.qxmd.com/collection/1133?ecd=wnl_readmost_250321

Hesitating to take the final step? “They made me feel so welcome here.”

https://news.va.gov/138878/hesitating-to-take-the-final-step/

Out of the shadows: One Veteran’s journey through trauma, substance use and renewal Brian Treasure didn’t realize the weight of his past until it started pulling him under

https://news.va.gov/139012/shadows-journey-trauma-substance-use-renewal/

New breast cancer screening recommendations Mammogram costs are covered for Veterans receiving care at VA

https://news.va.gov/138863/new-breast-cancer-screening-recommendations/

FDA approves pembrolizumab for HER2 positive gastric or gastroesophageal junction adenocarcinoma expressing PD-L1 (CPS ≥1)

https://www.fda.gov/drugs/resources-information-approved-drugs/fda-approves-pembrolizumab-her2-positive-gastric-or-gastroesophageal-junction-adenocarcinoma

FDA approves first treatment for adults with complement 3 glomerulopathy, a rare kidney disease, to reduce proteinuria

https://www.fda.gov/drugs/news-events-human-drugs/fda-approves-first-treatment-adults-complement-3-glomerulopathy-rare-kidney-disease-reduce?utm_medium=email&utm_source=govdelivery FDA Approves First Treatment for Adults with Complement 3 Glomerulopathy, a Rare Kidney Disease, to Reduce Proteinuria FDA approved Fabhalta (iptacopan) for the treatment of adults with complement 3 glomerulopathy (C3G) to reduce proteinuria. Fabhalta is an oral capsule, taken twice daily. Recommended dosing is available in the prescribing information. C3G is a rare disease that causes inflammation and damage to the kidney glomeruli, which are responsible for filtering blood and producing urine. In C3G, the complement system (proteins in the blood that play a critical role in the immune system) becomes abnormally activated. Complement products can become lodged in the glomeruli causing them to become leaky and harming their ability to filter blood. Waste products and toxins then build up in the blood, which decreases the kidneys’ ability to balance salts and minerals, decreases urine production, and causes continued kidney damage. Fabhalta increases the risk of serious and life-threatening infections caused by encapsulated bacteria, including Streptococcus pneumoniae, Neisseria meningitidis, and Haemophilus influenzae type b. Patients should complete or update vaccination for encapsulated bacteria at least 2 weeks before the first dose of Fabhalta, unless the risks of delaying treatment outweigh the risks of developing a serious infection. Health care providers should monitor patients for early signs and symptoms of serious infections and evaluate immediately if infection is suspected. Fabhalta may increase total cholesterol, LDL-cholesterol, and serum triglycerides. Health care providers should monitor patients’ serum lipid parameters periodically during treatment with Fabhalta and initiate cholesterol-lowering medication, if indicated. Fabhalta is available only through a restricted program under a Risk Evaluation and Mitigation Strategy (REMS). The most common adverse reactions (reported in at least 10% of patients) to Fabhalta were nasopharyngitis (common cold) and viral infections.

Study Illuminates the Structural Features of Memory Formation at the Cellular and Subcellular Levels NIH-funded study uses cutting-edge imaging techniques to reconstruct features underlying learning and memory in the mouse brain March 20, 2025 • Media Advisory

https://www.nimh.nih.gov/news/science-updates/2025/study-illuminates-the-structural-features-of-memory-formation-at-the-cellular-and-subcellular-levels In a recent study funded by the National Institutes of Health (NIH), researchers shed new light on memory encoding. The researchers exposed mice to a conditioning task and examined their hippocampus about one week later using cutting-edge technology such as 3-D electron microscopy and artificial intelligence. Researchers discovered that neurons involved in memory formation were not preferentially connected. They also found that these neurons reorganized their connections through an atypical connection called a multi-synaptic bouton. This study sheds new light on the fundamentally flexible nature of memory encoding and raises new questions and ideas for future exploration. Read More Study Findings

jueves, 20 de marzo de 2025

Zain Verjee is no longer hiding from psoriasis Long-time international TV news anchor shares her story

https://magazine.medlineplus.gov/article/zain-verjee-is-no-longer-hiding-from-psoriasis/

Breast cancer at 33: Telemundo host Adamari López leads with laughter López credits early detection to self-exam and regular checkups

https://magazine.medlineplus.gov/article/breast-cancer-at-33-telemundo-host-adamari-lopez-leads-with-laughter

Starting the conversation to improve mental health Actress Taraji P. Henson is starting the conversation to improve mental health using her platform, Henson is working to de-stigmatize depression and anxiety

https://magazine.medlineplus.gov/article/starting-the-conversation-to-improve-mental-health

Kristin Chenoweth wants to put migraine awareness center stage The Tony Award winner lets others with the condition know they’re not alone

https://magazine.medlineplus.gov/article/kristin-chenoweth-wants-to-put-migraine-awareness-center-stage

The power of music Soprano Renée Fleming teams with NIH on Sound Health Initiative

https://magazine.medlineplus.gov/article/the-power-of-music

Several kinds of acne products recalled over cancer risk, FDA says The recalled items include La Roche-Posay, Proactiv and Walgreens products Brie Stimson By Brie Stimson Fox News Published March 14, 2025 3:58pm EDT

Several kinds of acne products recalled over cancer risk, FDA says The recalled items include La Roche-Posay, Proactiv and Walgreens products Brie Stimson By Brie Stimson Fox News Published March 14, 2025 3:58pm EDT https://www.foxnews.com/health/several-kinds-acne-products-recalled-cancer-risk-fda-says

Deadly cancer type linked to obesity and high stress levels Healthy diet, exercise and mindfulness could reduce pancreatic cancer risk, study finds Melissa Rudy By Melissa Rudy Fox News Published March 15, 2025 5:17pm EDT

Deadly cancer type linked to obesity and high stress levels Healthy diet, exercise and mindfulness could reduce pancreatic cancer risk, study finds Melissa Rudy By Melissa Rudy Fox News Published March 15, 2025 5:17pm EDT https://www.foxnews.com/health/deadly-cancer-type-linked-obesity-high-stress-levels

Pain could be reduced by watching nature scenes, new study suggests Exposure to outdoor environments affects brain's pain centers, researchers say By Khloe Quill Fox News Published March 18, 2025 12:51pm EDT

Pain could be reduced by watching nature scenes, new study suggests Exposure to outdoor environments affects brain's pain centers, researchers say By Khloe Quill Fox News Published March 18, 2025 12:51pm EDT https://www.foxnews.com/health/pain-could-reduced-watching-nature-scenes-new-study-suggests

New outbreak of deadly bird flu strain confirmed for first time in 8 years The H7N9 strain was detected on a poultry farm in Mississippi Angelica Stabile By Angelica Stabile Fox News Published March 19, 2025 5:05pm EDT

New outbreak of deadly bird flu strain confirmed for first time in 8 years The H7N9 strain was detected on a poultry farm in Mississippi Angelica Stabile By Angelica Stabile Fox News Published March 19, 2025 5:05pm EDT https://www.foxnews.com/health/outbreak-deadly-bird-flu-strain-confirmed-first-time-8-years

Traveling amid measles, plus pet food recalls and cancer risk factors And more of the top Fox News Health stories and videos from the past week By Fox News Staff Fox News Published March 19, 2025 9:55pm EDT

Traveling amid measles, plus pet food recalls and cancer risk factors And more of the top Fox News Health stories and videos from the past week By Fox News Staff Fox News Published March 19, 2025 9:55pm EDT https://www.foxnews.com/health/traveling-amid-measles-outbreak-bird-flu-product-recalls-plus-cancer-linked-high-stress

Jillian Michaels reveals simple workout to extend your lifespan 'up to 7 years' 'Fitness is the No. 1 form of preventative medicine,' Michaels says Ashley J. DiMella By Ashley J. DiMella Fox News Published March 19, 2025 5:00am EDT

Jillian Michaels reveals simple workout to extend your lifespan 'up to 7 years' 'Fitness is the No. 1 form of preventative medicine,' Michaels says Ashley J. DiMella By Ashley J. DiMella Fox News Published March 19, 2025 5:00am EDT https://www.foxnews.com/health/jillian-michaels-reveals-simple-workout-extend-lifespan-7-years

4 troubling cancer trends you must know about in 2025 Oncologists reveal the warning signs that most concern them this year Angelica Stabile By Angelica Stabile Fox News Published March 17, 2025 3:19pm EDT

4 troubling cancer trends you must know about in 2025 Oncologists reveal the warning signs that most concern them this year Angelica Stabile By Angelica Stabile Fox News Published March 17, 2025 3:19pm EDT https://www.foxnews.com/health/4-troubling-cancer-trends-you-must-know-about-2025

Mother with rare ALS touts 'miracle drug' that has stopped her disease Since starting a clinical trial more than 7 years ago, Raziel Green says her symptoms have not gotten any worse Melissa Rudy By Melissa Rudy Fox News Published March 18, 2025 5:00am EDT

Mother with rare ALS touts 'miracle drug' that has stopped her disease Since starting a clinical trial more than 7 years ago, Raziel Green says her symptoms have not gotten any worse Melissa Rudy By Melissa Rudy Fox News Published March 18, 2025 5:00am EDT https://www.foxnews.com/health/mother-rare-als-touts-miracle-drug-has-stopped-her-disease

Cannabis use endangers heart health for certain group Marijuana impacts cardiac risk as soon as one hour after use, study finds Melissa Rudy By Melissa Rudy Fox News Published March 18, 2025 4:58pm EDT

Cannabis use endangers heart health for certain group Marijuana impacts cardiac risk as soon as one hour after use, study finds Melissa Rudy By Melissa Rudy Fox News Published March 18, 2025 4:58pm EDT https://www.foxnews.com/health/cannabis-use-endangers-heart-health-certain-group

Just 1 in 10 back pain treatments work, study says — what to do instead Pain is 'complex condition' that requires individual solutions, experts say Melissa Rudy By Melissa Rudy Fox News Published March 20, 2025 5:00am EDT

Just 1 in 10 back pain treatments work, study says — what to do instead Pain is 'complex condition' that requires individual solutions, experts say Melissa Rudy By Melissa Rudy Fox News Published March 20, 2025 5:00am EDT https://www.foxnews.com/health/just-1-10-back-pain-treatments-work-study-says-what-do-instead

A new vaccine is here to protect you and your loved ones from RSV this winter FDA approved a new vaccine for older adults and expanded approval for others

https://magazine.medlineplus.gov/article/a-new-vaccine-is-here-to-protect-you-and-your-loved-ones-from-rsv-this-winter December and January are peak months for respiratory syncytial virus (RSV) infections. While anyone can get RSV, severe infections are more common in young children and older adults. Fortunately, new vaccine approvals by the U.S. Food and Drug Administration (FDA) mean there are more options to avoid getting sick this winter.

Parkinson’s disease explained What you need to know about this movement disorder

https://magazine.medlineplus.gov/article/parkinsons-disease-explained/ Parkinson's disease (PD) is a progressive movement disorder of the nervous system. PD is one of the most common nervous system disorders, especially among older adults. It’s estimated to affect between 500,000 and 1 million Americans.