lunes, 31 de marzo de 2025
domingo, 30 de marzo de 2025
Withdrawal of life sustaining therapies in patients with or without acute brain injury +++
COMMENTS
Withdrawal of life sustaining therapies in patients with or without acute brain injury
Free with registration
https://www.thelancet.com/journals/lanres/article/PIIS2213-2600(25)00008-6/abstract?utm_campaign=conferencealerts&utm_medium=email&dgcid=hubspot_email_conferencealerts_isicem25&_hsenc=p2ANqtz-810NB0yb5F8Y3mQoTvgEnf3PBxQ_x-1_TZ_8qLvO7IHfC9d4cH8fwl837ny6wVo7ZBi_HMBcBsoxGB_MQIwToj-LKXew&_hsmi=352808950&utm_content=352808950&utm_source=hs_email
Preoxygenation for tracheal intubation in adults who are critically ill: time to abandon the facemask?
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https://www.thelancet.com/journals/lanres/article/PIIS2213-2600(25)00056-6/abstract?utm_campaign=conferencealerts&utm_medium=email&dgcid=hubspot_email_conferencealerts_isicem25&_hsenc=p2ANqtz-_O2ezWCvjfoZz5Q5ESOfmMX6NmtsAph4KPJkiMLFDXsHHDjpAl6I4HvHH8Ww64Xvi02BFm_leL5eaPP96IfcdY-QCaLA&_hsmi=352808950&utm_content=352808950&utm_source=hs_email
Nasal high-flow oxygen for apnoeic oxygenation during emergency endotracheal intubation of children
Free with registration until Mar 29, 2025
https://www.thelancet.com/journals/lanres/article/PIIS2213-2600(25)00085-2/abstract?utm_campaign=conferencealerts&utm_medium=email&dgcid=hubspot_email_conferencealerts_isicem25&_hsenc=p2ANqtz--vIxGOCPiYLzDZXz_tTE-g7z71XuylR7mYeYYxliVH1B5fYWRJq79KXw5gzRg4Z2kKmV_acKuRo7B_XU9omyDPco3h-Q&_hsmi=352808950&utm_content=352808950&utm_source=hs_email
Decisions to withdraw or withhold life-sustaining therapies in patients with and without acute brain injury: a secondary analysis of two prospective cohort studies +++
Decisions to withdraw or withhold life-sustaining therapies in patients with and without acute brain injury: a secondary analysis of two prospective cohort studies
Free with registration
https://www.thelancet.com/journals/lanres/article/PIIS2213-2600(24)00404-1/abstract?utm_campaign=conferencealerts&utm_medium=email&dgcid=hubspot_email_conferencealerts_isicem25&_hsenc=p2ANqtz-9yZxutbZcCCq90aHFGFVGigqyWw0ryhTVRtZORXNKm5SfJl2a2q36-jaAm66P9iSc_Ff7A_ocSAOASqzeQZxPim9GNCA&_hsmi=352808950&utm_content=352808950&utm_source=hs_email
Preoxygenation strategies for intubation of patients who are critically ill: a systematic review and network meta-analysis of randomised trials
Free with registration
https://www.thelancet.com/journals/lanres/article/PIIS2213-2600(25)00029-3/abstract?utm_campaign=conferencealerts&utm_medium=email&dgcid=hubspot_email_conferencealerts_isicem25&_hsenc=p2ANqtz-8YsCucNxqabXI7lq-b43RHwLyzSAs9pQQTyNsn-LUHgTnhstNAOxLwjykk17dC8vGq4bSbqM1mRCOCdC5KHUt9vuGqwg&_hsmi=352808950&utm_content=352808950&utm_source=hs_email
Effectiveness of nasal high-flow oxygen during apnoea on hypoxaemia and intubation success in paediatric emergency and ICU settings: a randomised, controlled, open-label trial
Free with registration
https://www.thelancet.com/journals/lanres/article/PIIS2213-2600(25)00074-8/abstract?utm_campaign=conferencealerts&utm_medium=email&dgcid=hubspot_email_conferencealerts_isicem25&_hsenc=p2ANqtz-8jUBeMLPijDy0bwg1TQH1_RbLw2zWd7vX1hcRb35Aj7gT-MdubfKY9D3CrwuuA-UaW9JbfTZyquqOSQMhV3_YzefrtNQ&_hsmi=352808950&utm_content=352808950&utm_source=hs_email
Game On! Play Your Way to Financial Freedom By Ivanhoe Broadcast News on April 4, 2025
Game On! Play Your Way to Financial Freedom
By Ivanhoe Broadcast News on April 4, 2025
https://www.ivanhoe.com/?p=35258&preview=1&_ppp=199a418261
The Big Disconnect: How To Hang Up And Reconnect With Family By Ivanhoe Broadcast News on March 27, 2025
The Big Disconnect: How To Hang Up And Reconnect With Family
By Ivanhoe Broadcast News on March 27, 2025
https://www.ivanhoe.com/smart-living/the-big-disconnect-how-to-hang-up-and-reconnect-with-family/
Don’t Get Scammed! How To Spot Fake Job Ads By Ivanhoe Broadcast News on April 2, 2025
Don’t Get Scammed! How To Spot Fake Job Ads
By Ivanhoe Broadcast News on April 2, 2025
https://www.ivanhoe.com/?p=35252&preview=1&_ppp=30c768429d
Sun, Sand And Scams! Spring Break Beware! By Ivanhoe Broadcast News on April 1, 2025
Sun, Sand And Scams! Spring Break Beware!
By Ivanhoe Broadcast News on April 1, 2025
https://www.ivanhoe.com/?p=35249&preview=1&_ppp=3f10dc9fd2
RESILIENT ROOTS: EMPOWERING LATINO COMMUNITIES TO THRIVE
Resilient Roots: Empowering Latino Communities to Thrive
By Ivanhoe Broadcast News on March 31, 2025
https://www.ivanhoe.com/?p=35205&preview=1&_ppp=8ed3416d74
High-Dose Vitamin D Curbs Disease Activity in Early Multiple Sclerosis Megan Brooks March 13, 2025 +++++ +++
BREAKTHROUGHS & SETBACKS
High-Dose Vitamin D Tames Early MS
High-Dose Vitamin D Curbs Disease Activity in Early Multiple Sclerosis
Megan Brooks
March 13, 2025
https://www.medscape.com/viewarticle/high-dose-vitamin-d-curbs-disease-activity-early-multiple-2025a100062t?ecd=mkm_ret_250329_mscpmrk_neuro_topcontent_etid7324753&uac=148436CN&impID=7324753
Neurologic Dysfunction & Microplastics Linked
Marine Microplastics Linked to Neurologic Dysfunction
Megan Brooks
March 07, 2025
https://www.medscape.com/viewarticle/marine-microplastics-linked-neurologic-dysfunction-2025a10005na?ecd=mkm_ret_250329_mscpmrk_neuro_topcontent_etid7324753&uac=148436CN&impID=7324753
MS Subtyping: Does It Really Matter?
Is MS Subtyping Clinically Meaningful? Experts Weigh In
Ted Bosworth
March 14, 2025
https://www.medscape.com/viewarticle/ms-subtyping-clinically-meaningful-experts-weigh-2025a100066h?ecd=mkm_ret_250329_mscpmrk_neuro_topcontent_etid7324753&uac=148436CN&impID=7324753
Stopping DMTs in Older MS Patients: What the Data Show
Stopping DMTs in Older MS Patients: What the Data Show
Ted Bosworth
March 03, 2025
https://www.medscape.com/viewarticle/stopping-dmts-older-ms-patients-what-data-show-2025a100058n?ecd=mkm_ret_250329_mscpmrk_neuro_topcontent_etid7324753&uac=148436CN&impID=7324753
Teen's Death Raises Concerns for Gene Therapy Tx
Sarepta Says Teen Died After Its Gene Therapy Treatment
Sriparna Roy And Bhanvi Satija
March 18, 2025
https://www.medscape.com/s/viewarticle/sarepta-reports-teen-death-after-gene-therapy-treatment-2025a10006h3?ecd=mkm_ret_250329_mscpmrk_neuro_topcontent_etid7324753&uac=148436CN&impID=7324753
GUIDELINES & CLINICAL INSIGHTS
New Guidance on Seizures, Driving, and Medical Reporting
New Guidance on Seizures, Driving, and Medical Reporting
Patrice Wendling
March 12, 2025
https://www.medscape.com/viewarticle/new-guidance-seizures-driving-and-medical-reporting-2025a1000621?ecd=mkm_ret_250329_mscpmrk_neuro_topcontent_etid7324753&uac=148436CN&impID=7324753
How to Deliver a Dementia Diagnosis
Breaking Bad News: Guidance on Disclosing a Dementia Diagnosis
Megan Brooks
March 03, 2025
https://www.medscape.com/viewarticle/breaking-bad-news-guidance-disclosing-dementia-diagnosis-2025a100057h?ecd=mkm_ret_250329_mscpmrk_neuro_topcontent_etid7324753&uac=148436CN&impID=7324753
OTC Analgesics Improve Concussion Outcomes
Over-the-Counter Analgesics Improve Concussion Outcomes
Pauline Anderson
March 13, 2025
https://www.medscape.com/viewarticle/over-counter-analgesics-improve-concussion-outcomes-2025a100063h?ecd=mkm_ret_250329_mscpmrk_neuro_topcontent_etid7324753&uac=148436CN&impID=7324753
sábado, 29 de marzo de 2025
Treatment & Guidelines: ASCO Updates Treatment Guidance for Newly Diagnosed, Advanced Ovarian Cancer Christos Evangelou, MSc, PhD ++++ ++++
Treatment & Guidelines
ASCO Guidelines: Ovarian Cancer Updates
ASCO Updates Treatment Guidance for Newly Diagnosed, Advanced Ovarian Cancer
Christos Evangelou, MSc, PhD
February 24, 2025
https://www.medscape.com/viewarticle/asco-updates-treatment-guidance-newly-diagnosed-advanced-2025a10004ox?ecd=mkm_ret_250329_mscpmrk_onc-gyno_etid7324513&uac=148436CN&impID=7324513
Cervical Cancer: Does Adding Chemo to RT Improve Survival?
Does Adding Adjuvant Chemo to Radiation Improve Survival in Early Cervical Cancer?
Megan Brooks
March 24, 2025
https://www.medscape.com/viewarticle/does-adding-adjuvant-chemo-radiation-improve-survival-early-2025a10006xd?ecd=mkm_ret_250329_mscpmrk_onc-gyno_etid7324513&uac=148436CN&impID=7324513
Pembrolizumab Improves PFS in Cervical Cancer
Pembrolizumab Improves 36-Month PFS in Cervical Cancer
Jim Kling
March 18, 2025
https://www.medscape.com/viewarticle/pembrolizumab-improves-36-month-pfs-cervical-cancer-2025a10006gu?ecd=mkm_ret_250329_mscpmrk_onc-gyno_etid7324513&uac=148436CN&impID=7324513
Is Adjuvant Chemo Necessary for Intermediate-Risk Cervical Cancer?
Do Patients With Intermediate-Risk Cervical Cancer Need Adjuvant Chemotherapy?
Whitney McKnight
March 20, 2025
https://www.medscape.com/viewarticle/do-patients-intermediate-risk-cervical-cancer-need-adjuvant-2025a10006q4?ecd=mkm_ret_250329_mscpmrk_onc-gyno_etid7324513&uac=148436CN&impID=7324513
Detection & Research
Tampon Test for Endometrial Cancer
Tampon-Based Test Detects Endometrial Cancer Using Vaginal Fluid Biomarkers
M. Alexander Otto, PA, MMS
March 25, 2025
https://www.medscape.com/viewarticle/tampon-based-test-detects-endometrial-cancer-using-vaginal-2025a1000706?ecd=mkm_ret_250329_mscpmrk_onc-gyno_etid7324513&uac=148436CN&impID=7324513
Risk-Reduction Surgery Benefit in Non-BRCA Ovarian Cancer?
TNBC Outcomes Show Progress
Medscape Medical News March 28, 2025
https://www.medscape.com/resource/ovarian-cancer?ecd=mkm_ret_250329_mscpmrk_onc-gyno_etid7324513&uac=148436CN&impID=7324513
Adjuvant Chemo vs Radiotherapy Alone in Cervical Cancer
Do Patients With Intermediate-Risk Cervical Cancer Need Adjuvant Chemotherapy?
Whitney McKnight
March 20, 2025
https://www.medscape.com/viewarticle/do-patients-intermediate-risk-cervical-cancer-need-adjuvant-2025a10006q4?ecd=mkm_ret_250329_mscpmrk_onc-gyno_etid7324513&uac=148436CN&impID=7324513
What's New in Endometrial Cancer Research?
Endometrial Cancer: Molecular Classification, Genetics, When to Rebiopsy, and What's New in the Research
Ursula A. Matulonis, MD; Katherine Fuh, MD, PhD
https://www.medscape.com/viewarticle/1001980?ecd=mkm_ret_250329_mscpmrk_onc-gyno_etid7324513&uac=148436CN&impID=7324513
March 12, 2025
Why is this startup growing synthetic brains from urine? By Zachy Hennessey March 25, Updated March 27
Why is this startup growing synthetic brains from urine?
Itay&Beyond grows brain tissue from patient urine stem cells to test neurological drugs, training the chips via video games to detect autism and other brain disorders.
https://www.israel21c.org/why-is-this-startup-growing-synthetic-brains-from-urine/
jueves, 27 de marzo de 2025
Learning and Education to ADvance and Empower Rare Disease Drug Developers (LEADER 3D)
https://www.fda.gov/about-fda/accelerating-rare-disease-cures-arc-program/learning-and-education-advance-and-empower-rare-disease-drug-developers-leader-3d?utm_medium=email&utm_source=govdelivery
Now Available: Two LEADER 3D Videos on Understanding the Importance of Endpoints and Considerations for Collecting and Using Natural History Data
The CDER ARC Program’s Learning and Education to ADvance and Empower Rare Disease Drug Developers (LEADER 3D) initiative published two new videos titled “Understanding the Importance of Endpoints in Rare Disease Drug Development” and “Considerations for Collecting and Using Natural History Study Data that are Fit for Use in the Regulatory Setting” to the educational video series. The videos provide an overview of important considerations for selecting endpoints when designing clinical trials, and concepts to consider when determining how to leverage natural history study data in rare disease drug development programs.
miércoles, 26 de marzo de 2025
Hair loss? Gut health issues? Dr. Nicole Saphier reveals smart fixes Dr. Nicole Saphier discusses two key health issues facing many Americans By Khloe Quill Fox News Published March 24, 2025 5:20pm EDT
Hair loss? Gut health issues? Dr. Nicole Saphier reveals smart fixes
Dr. Nicole Saphier discusses two key health issues facing many Americans
By Khloe Quill Fox News
Published March 24, 2025 5:20pm EDT
https://www.foxnews.com/health/hair-loss-gut-health-issues-dr-nicole-saphier-fixes
Dengue fever cases rising in popular spring break locations, CDC alerts Amid spring break, transmission ‘remains high’ among U.S. travelers Angelica Stabile By Angelica Stabile Fox News Published March 24, 2025 1:33pm EDT
Dengue fever cases rising in popular spring break locations, CDC alerts
Amid spring break, transmission ‘remains high’ among U.S. travelers
Angelica Stabile By Angelica Stabile Fox News
Published March 24, 2025 1:33pm EDT
https://www.foxnews.com/health/dengue-fever-cases-rising-popular-spring-break-locations-cdc-alerts
Men face higher cancer risk with this specific body fat measurement The same factor wasn’t linked to a higher risk in women, researchers found Melissa Rudy By Melissa Rudy Fox News Published March 25, 2025 5:00am EDT
Men face higher cancer risk with this specific body fat measurement
The same factor wasn’t linked to a higher risk in women, researchers found
Melissa Rudy By Melissa Rudy Fox News
Published March 25, 2025 5:00am EDT
https://www.foxnews.com/health/men-face-higher-cancer-risk-specific-body-fat-measurement
Heart disease risk higher for women who have these unhealthy lifestyle habits Impact was not as high for men with the same habits, study found Melissa Rudy By Melissa Rudy Fox News Published March 25, 2025 3:15pm EDT
Heart disease risk higher for women who have these unhealthy lifestyle habits
Impact was not as high for men with the same habits, study found
Melissa Rudy By Melissa Rudy Fox News
Published March 25, 2025 3:15pm EDT
https://www.foxnews.com/health/heart-disease-risk-higher-women-have-unhealthy-lifestyle-habits
First confirmed case of measles in Washington, D.C. investigated by health officials Those with measles are contagious four days before a rash appears and up to four days after Jasmine Baehr By Jasmine Baehr Fox News Published March 25, 2025 6:39pm EDT
First confirmed case of measles in Washington, D.C. investigated by health officials
Those with measles are contagious four days before a rash appears and up to four days after
Jasmine Baehr By Jasmine Baehr Fox News
Published March 25, 2025 6:39pm EDT
https://www.foxnews.com/health/first-confirmed-case-measles-washington-d-c-investigated-health-officials
martes, 25 de marzo de 2025
FDA Approves First Treatment for C3 Glomerulopathy
Mar 25, 2025| Autoimmune / Autoinflammatory Disorders, Kidney And Urinary Diseases, Regulations, Treatment
FDA Approves First Treatment for C3 Glomerulopathy
The U.S. Food and Drug Administration has approved…
https://checkrare.com/
Improved Growth in Children Suffering from Fabry Disease Treated With Agalsidase Beta By: Madaline Spencer| Published on: Mar 11, 2025 +++
Improved Growth in Children Suffering from Fabry Disease Treated With Agalsidase Beta
By: Madaline Spencer| Published on: Mar 11, 2025
https://checkrare.com/improved-growth-in-children-suffering-from-fabry-disease-treated-with-agalsidase-beta/
Treatment Comparisons for Left Ventricular Mass Index in Fabry Disease
By: Madaline Spencer| Published on: Mar 10, 2025
https://checkrare.com/treatment-comparisons-for-left-ventricular-mass-index-in-fabry-disease/
Five-Year Study Results in Patients With Fabry Disease
By: Madaline Spencer| Published on: Feb 26, 2025
https://checkrare.com/five-year-study-results-in-patients-with-fabry-disease/
Watch the DAYBUE® (trofinetide) in Practice Video Series to Hear Expert Insights on the First Treatment for This Rare Disease By: CheckRare Staff | Updated on: Jan 28, 2025
https://checkrare.com/watch-the-daybue-trofinetide-in-practice-video-series-to-hear-expert-insights/
Rett syndrome thought leaders discuss how DAYBUE® (trofinetide), the first and only FDA-approved treatment for Rett syndrome in adults and pediatric patients 2 years of age and older, plays a role in their patients’ treatment plans, while shedding light on their personal experiences with DAYBUE in their practices.[1,2] Watch the entire DAYBUE in Practice video series below to learn about the DAYBUE clinical trial results, gastrointestinal (GI) management strategies, and how DAYBUE plays an important role in comprehensive Rett syndrome care.
Improving Health Equity in Hereditary Angioedema (HAE): A Panel Discussion Aleena Banerji, MD, Timothy Craig, DO, Marc Riedl, MD
https://checkrare.com/improving-health-equity-in-hereditary-angioedema-hae-a-panel-discussion/
Hereditary angioedema (HAE) is a rare genetic disease that results in immunologic attacks that can be life-threatening. HAE is the result of reduced levels of C1-inhibitor, a protein involved in various physiological processes in plasma, most notably with the complement system. This panel discussion by three clinical research leaders in HAE, Drs. Aleena Banerji, Timothy Craig, and Marc Riedl, provide an overview of the discrepancies in care observed in certain patient populations, as well as a discussion on best practices to reduce those inequalities moving forward.
lunes, 24 de marzo de 2025
Obesity most prevalent in these 3 southern cities New report analyzes food intake, fitness and health consequences Angelica Stabile By Angelica Stabile Fox News Published March 20, 2025 4:15pm EDT
Obesity most prevalent in these 3 southern cities
New report analyzes food intake, fitness and health consequences
Angelica Stabile By Angelica Stabile Fox News
Published March 20, 2025 4:15pm EDT
https://www.foxnews.com/health/obesity-most-prevalent-3-southern-cities
Diabetes risk lowered by eating one surprisingly sweet food, study suggests Tropical fruit could support more balanced blood sugar levels, researchers say By Khloe Quill Fox News Published March 20, 2025 1:50pm EDT
Diabetes risk lowered by eating one surprisingly sweet food, study suggests
Tropical fruit could support more balanced blood sugar levels, researchers say
By Khloe Quill Fox News
Published March 20, 2025 1:50pm EDT
https://www.foxnews.com/health/diabetes-risk-lowered-eating-surprisingly-sweet-food-study-shows
Parkinson’s cases could double globally by 2050, study reveals Neurodegenerative diseases predicted to surpass cancer as second leading cause of death worldwide by 2040 By Khloe Quill Fox News Published March 21, 2025 11:38am EDT
Parkinson’s cases could double globally by 2050, study reveals
Neurodegenerative diseases predicted to surpass cancer as second leading cause of death worldwide by 2040
By Khloe Quill Fox News
Published March 21, 2025 11:38am EDT
https://www.foxnews.com/health/parkinsons-cases-could-double-globally-2050-study-reveals
Kids with Down syndrome can live 'abundant lives,' dad tells Fox News contributor Fox News contributor Tom Shillue speaks to the dad of a child with Down syndrome on World Down Syndrome Day Melissa Rudy By Melissa Rudy , Angelica Stabile Fox News Published March 21, 2025 2:43pm EDT
Kids with Down syndrome can live 'abundant lives,' dad tells Fox News contributor
Fox News contributor Tom Shillue speaks to the dad of a child with Down syndrome on World Down Syndrome Day
Melissa Rudy By Melissa Rudy , Angelica Stabile Fox News
Published March 21, 2025 2:43pm EDT
https://www.foxnews.com/health/kids-down-syndrome-can-live-abundant-lives-dad-tells-fox-news-contributor
Alzheimer’s-related dementia could be prevented by experimental drug, researchers say Medication is designed to reduce amyloid in the brain, a hallmark of Alzheimer’s Melissa Rudy By Melissa Rudy Fox News Published March 22, 2025 5:00am EDTAlzheimer’s-related dementia could be prevented by experimental drug, researchers say Medication is designed to reduce amyloid in the brain, a hallmark of Alzheimer’s Melissa Rudy By Melissa Rudy Fox News Published March 22, 2025 5:00am EDT
Alzheimer’s-related dementia could be prevented by experimental drug, researchers say
Medication is designed to reduce amyloid in the brain, a hallmark of Alzheimer’s
Melissa Rudy By Melissa Rudy Fox News
Published March 22, 2025 5:00am EDT
https://www.foxnews.com/health/alzheimers-related-dementia-could-prevented-experimental-drug-researchers-say
Parents of girl who died after measles infection said they wouldn't get MMR vaccine West Texas couple told Children’s Health Defense their daughter also had pneumonia Melissa Rudy By Melissa Rudy Fox News Published March 22, 2025 1:41pm EDT
Parents of girl who died after measles infection said they wouldn't get MMR vaccine
West Texas couple told Children’s Health Defense their daughter also had pneumonia
Melissa Rudy By Melissa Rudy Fox News
Published March 22, 2025 1:41pm EDT
https://www.foxnews.com/health/parents-girl-died-measles-infection-wouldnt-get-mmr-vaccine
Prostate cancer risk increases by 45% among men who share one troubling behavior New health study highlights importance of medical screening Melissa Rudy By Melissa Rudy Fox News Published March 22, 2025 3:53pm EDT
Prostate cancer risk increases by 45% among men who share one troubling behavior
New health study highlights importance of medical screening
Melissa Rudy By Melissa Rudy Fox News
Published March 22, 2025 3:53pm EDT
https://www.foxnews.com/health/prostate-cancer-risk-increases-45-among-men-share-behavior
Tennessee reports first measles case amid U.S. outbreak According to the Tennessee Department of Health, the Volunteer State has recorded its first case of measles this year amid a nationwide outbreak Peter D'Abrosca By Peter D'Abrosca Fox News Published March 23, 2025 5:29pm EDT
Tennessee reports first measles case amid U.S. outbreak
According to the Tennessee Department of Health, the Volunteer State has recorded its first case of measles this year amid a nationwide outbreak
Peter D'Abrosca By Peter D'Abrosca Fox News
Published March 23, 2025 5:29pm EDT
https://www.foxnews.com/health/tennessee-reports-first-measles-case-amid-u-s-outbreak
Diabetes breakthrough: Chinese trial paves way for insulin-free future In a groundbreaking treatment, insulin-producing cells sourced from a young woman's own body were successfully implanted, effectively eliminating the need for daily injections Daniel Khaykelson/Davidson Institute of Science|Yesterday | 18:11
Diabetes breakthrough: Chinese trial paves way for insulin-free future
In a groundbreaking treatment, insulin-producing cells sourced from a young woman's own body were successfully implanted, effectively eliminating the need for daily injections
Daniel Khaykelson/Davidson Institute of Science|Yesterday | 18:11
https://www.ynetnews.com/health_science/article/bkn8jp62je
‘Out of breaking points comes opportunity’: Israel maps mental health tech boom After October 7, Israel sees a mental health tech boom: 117 startups tackling trauma, resilience with AI, self-care and automation; Collaboration, funding and policy changes are crucial to accelerate healing, say experts Maayan Hoffman/The Media Line|07:27
‘Out of breaking points comes opportunity’: Israel maps mental health tech boom
After October 7, Israel sees a mental health tech boom: 117 startups tackling trauma, resilience with AI, self-care and automation; Collaboration, funding and policy changes are crucial to accelerate healing, say experts
Maayan Hoffman/The Media Line|07:27
https://www.ynetnews.com/health_science/article/sy00ndian1x
domingo, 23 de marzo de 2025
Helping parents fight their children’s eating disorders An AI app founded by the parent of a child with anorexia helps families navigate treatment plans for the growing number of children with eating disorders.Helping parents fight their children’s eating disorders An AI app founded by the parent of a child with anorexia helps families navigate treatment plans for the growing number of children with eating disorders.
UP IN SMOKE: THE IMPACT OF WILDFIRES ON LITTLE LUNGS
Up In Smoke: The Impact of Wildfires on Little Lungs
By Ivanhoe Broadcast News on March 29, 2025
https://www.ivanhoe.com/?p=35200&preview=1&_ppp=8f05e4d928
REFRIGERATOR RULES: WHAT TURNS TOXIC AND WHAT WON’T?
Refrigerator Rules: What Turns Toxic And What Won’t?
By Ivanhoe Broadcast News on March 28, 2025
https://www.ivanhoe.com/?p=35220&preview=1&_ppp=4ec4ab5ded
HUMAN HACKING: WHEN CYBER CRIMINALS TARGET YOU
Human Hacking: When Cyber Criminals Target You
By Ivanhoe Broadcast News on March 27, 2025
https://www.ivanhoe.com/?p=35217&preview=1&_ppp=866df7974b
SWEET DECEPTION: SNEAKY PLACES SUGAR HIDES
Sweet Deception: Sneaky Places Sugar Hides
By Ivanhoe Broadcast News on March 26, 2025
https://www.ivanhoe.com/?p=35214&preview=1&_ppp=51962c418f
FIVE STARS OR FAKE: SPOTTING DECEPTIVE ONLINE REVIEWS
Five Stars Or Fake: Spotting Deceptive Online Reviews
By Ivanhoe Broadcast News on March 25, 2025
https://www.ivanhoe.com/?p=35211&preview=1&_ppp=a17eeba00c
IT’S A SPRING THING: CLEAN UP YOUR LIFE TO LIVE LONGER
It’s A Spring Thing: Clean Up Your Life To Live Longer
By Ivanhoe Broadcast News on March 24, 2025
https://www.ivanhoe.com/?p=35208&preview=1&_ppp=c464d723da
sábado, 22 de marzo de 2025
Rare Diseases: Betting on the pharma package for timely and equitable access, still awaiting an EU Action Plan
https://www.euractiv.com/section/health-consumers/news/rare-diseases-betting-on-the-pharma-package-for-timely-and-equitable-access-still-awaiting-an-eu-action-plan/
In this recent Euractiv article, Valentina Bottarelli, our Head of Policy and Public Affairs, called for a European Action Plan for Rare Diseases to unify existing efforts and create a coherent strategy that ensures health equity, faster diagnoses, and better access to treatments. She also elaborated on the ongoing reforms to the EU's pharmaceutical legislation and their centrality to strengthening patient engagement, securing medicine supply, and fostering innovation.
Podcast: Rare on Air
https://www.eurordis.org/rare-on-air/
Rare on Air Stories
Don't forget to listen to our bonus podcast series marking Rare Disease Day! Hosted by Julien Poulain, the Rare on Air Stories series presents the striking personal stories of individuals living with a rare disease across the globe. From Australia to Mexico, Nepal to Nigeria and the U.S. to the U.K., each episode shares deeply moving personal experiences. Listen now to our latest episode, where we follow the journey of Noah from the United States! Listen to the podcast by subscribing to Spotify, Apple Podcasts, Amazon Music, or YouTube.
39th Workshop of the EURORDIS Round Table of Companies (ERTC): Addressing systemic inequalities through patient-driven innovation & research
https://www.eurordis.org/39th-ertc/
ERTC Workshop
Last month, our 39th EURORDIS Round Table of Companies (ERTC) Workshop in Brussels focused on patient-driven innovation to address systemic health inequalities. The workshop focused on integrating patients' priorities into future EU research policies and funding. The discussions explored the need to enhance clinical trials, leveraging public-private investments, corroborating healthcare systems, and promoting fairness in newborn screening.
EURORDIS Membership Meeting (EMM) 2025 March 2025
https://www.eurordis.org/eurordis-membership-meeting-emm-2025/
This year’s EURORDIS Membership Meeting will be held in Riga, Latvia, on 22-24 May. This event represents an invaluable opportunity for the members of the rare disease community to meet while sharing knowledge and building partnerships. Participants will explore topics such as advocacy at national and EU levels, volunteer involvement in healthcare, and leveraging Rare Barometer findings for advocacy. https://www.eurordis.org/rare-barometer/english/
SANT launches public consultation on rare diseases
https://www.europarl.europa.eu/news/en/press-room/20250227IPR27074/sant-launches-public-consultation-on-rare-diseases
The European Parliament Committee on Public Health (SANT) has opened a public Consultation on Rare Diseases to identify the challenges faced by those living with a rare disease and the potential EU actions to address them. With SANT now a fully-fledged parliamentary committee, the consultation presents a key moment to advocate for better funding, cooperation, and recognition of our community's unmet needs. EURORDIS' response highlights policy priorities, and you can submit your own response by 31 March! For questions or feedback, contact valentina.bottarelli@eurordis.org.
Have your say: Help shape the future of rare disease policy in Europe
The European Parliament’s Committee on Public Health (SANT), newly established as a fully-fledged committee, is responsible for shaping EU policies on healthcare, pharmaceutical legislation, and public health. It has now launched a Consultation on Rare Diseases, seeking input from patients, caregivers, researchers, healthcare professionals, and organisations working in the field.
https://www.eurordis.org/publications/eurordis-submission-sant-consultation/
Decreasing the invasiveness of deep brain stimulation
Decreasing the invasiveness of deep brain stimulation: Researchers are developing a preclinical method to stimulate the brain without drilling into the skull by guiding a catheter through the cerebrospinal fluid.
Deep brain stimulation—the application of electricity to specific deep brain regions to modulate their function—has been used clinically for over 25 years. This technique is used to monitor and treat neurological conditions, especially movement disorders, such as Parkinson’s disease and epilepsy. Yet many of these interfaces are highly invasive, as they require removing part of the skull to implant electrodes in the brain. Finding a way to monitor and stimulate the central nervous system in a less intrusive way has been a holy grail for those in the neuromodulation field.
Now, a collaborative team of NIH-funded researchers at Rice University and The University of Texas are developing a method to access and stimulate deep brain regions without drilling into the skull. They engineered a tiny pulse generator that can be implanted in the spine following a lumbar puncture. This pulse generator is connected to a stimulating catheter, which can be guided through the cerebrospinal fluid to the surface of the brain. After preliminary experiments in human cadavers, the team successfully used the device to record and stimulate brain activity in sheep with the aid of a wireless interface. Their work was recently published in Nature Biomedical Engineering.
Seasonal Allergies at a Glance
https://www.nccih.nih.gov/health/seasonal-allergies-at-a-glance?nav=govd
As spring approaches, seasonal allergic rhinitis—also called hay fever—becomes a problem for some people. Symptoms may include sneezing, coughing, a runny or stuffy nose, and itching in the eyes, nose, mouth, and throat. Many complementary health approaches have been studied for allergic rhinitis, and there’s evidence that a few may help.
Rinsing the sinuses with a neti pot (a device that comes from the Ayurvedic tradition) or other devices may be a useful addition to conventional treatment for seasonal allergies. Make sure to use only distilled, sterile, or boiled and cooled water; tap water may not be safe for use as a nasal rinse.
There’s evidence that acupuncture may be helpful for seasonal allergy symptoms.
Some studies of probiotics for allergies have had promising results, but others have not. It’s possible that only some types of probiotics are helpful.
Withdrawal of life sustaining therapies in patients with or without acute brain injury +++
COMMENTS
Withdrawal of life sustaining therapies in patients with or without acute brain injury
Free with registration
https://www.thelancet.com/journals/lanres/article/PIIS2213-2600(25)00008-6/abstract?utm_campaign=conferencealerts&utm_medium=email&dgcid=hubspot_email_conferencealerts_isicem25&_hsenc=p2ANqtz--rQN6km016zetaUjkoDznhldhX3grKw1VNNzDreQ25CnzsSWHhX25e-wN4Twkwf9ejc7mPjv2aGMqaNhhRh3GplxcJMQ&_hsmi=352808851&utm_content=352808851&utm_source=hs_email
Preoxygenation for tracheal intubation in adults who are critically ill: time to abandon the facemask?
Free with registration
https://www.thelancet.com/journals/lanres/article/PIIS2213-2600(25)00056-6/abstract?utm_campaign=conferencealerts&utm_medium=email&dgcid=hubspot_email_conferencealerts_isicem25&_hsenc=p2ANqtz-9FptrEp4QRM1yekX7fB2o1JwzC59KdPyEtMt0qhIDwd-xO3Rb6OKrWDWAkiWNXISUvnyQUyCg7YvGs_NrOzHPb5PDb6Q&_hsmi=352808851&utm_content=352808851&utm_source=hs_email
Nasal high-flow oxygen for apnoeic oxygenation during emergency endotracheal intubation of children
Free with registration until Mar 29, 2025
https://www.thelancet.com/journals/lanres/article/PIIS2213-2600(25)00085-2/abstract?utm_campaign=conferencealerts&utm_medium=email&dgcid=hubspot_email_conferencealerts_isicem25&_hsenc=p2ANqtz-8ysi4xFSEa7P680VqjRTHyMLr8p9fBZqqTjhXgC9ZiPAH_53o6OX9XPklbv0LTgdritcdmAixx-rG-DpySoqeTCVXycA&_hsmi=352808851&utm_content=352808851&utm_source=hs_email
viernes, 21 de marzo de 2025
Precision T-Cell Therapy Improves Blood Cancer Outcomes Edited by Susan Ruel, PhD March 21, 2025 +++++
Precision T-Cell Therapy Improves Blood Cancer Outcomes
Edited by Susan Ruel, PhD
March 21, 2025
https://www.medscape.com/viewarticle/precision-t-cell-therapy-improves-blood-cancer-outcomes-2025a10006rv
3D Total Body Photography Shown to Decrease Biopsies, Improve Dx of Nonmelanoma Skin Cancers
Richard Mark Kirkner
March 21, 2025
https://www.medscape.com/viewarticle/3d-total-body-photography-shown-decrease-biopsies-improve-dx-2025a10006r7
CA-125 Shows Less Accuracy in Black and American Indian Patients with Ovarian Cancer
Edited by Katie Lennon
March 21, 2025
https://www.medscape.com/viewarticle/ca-125-shows-less-accuracy-black-and-american-indian-2025a10006rk
Do Patients With Intermediate-Risk Cervical Cancer Need Adjuvant Chemotherapy?
Whitney McKnight
March 20, 2025
https://www.medscape.com/viewarticle/do-patients-intermediate-risk-cervical-cancer-need-adjuvant-2025a10006q4
Can Adjuvant Immunotherapy Boost Survival Outcomes in Advanced Nasopharyngeal Cancer?
Edited by Gargi Mukherjee
March 20, 2025
https://www.medscape.com/viewarticle/can-adjuvant-immunotherapy-boost-survival-outcomes-advanced-2025a10006o6
Encapsulation of a Single-Stranded Form of DNA Impurities into the Capsid of a Recombinant Adeno-Associated Virus
https://www.liebertpub.com/doi/10.1089/hum.2024.264?utm_campaign=MAL_HUM&utm_medium=email&_hsenc=p2ANqtz-8iXI7dSloS6J_pZvH0Om8Np3gdmU7z_JfPtlgF9Df1-IsCiO8RmrWHSt89dd8QhGuOUGtewNJF1u_wWkpOb2ZtWaNEWA&_hsmi=352880154&utm_content=352880154&utm_source=hs_email
Evaluating DNA Impurities in Recombinant Adeno-Associated Virus
New Rochelle, NY, March 20, 2025—A new study in the peer-reviewed journal Human Gene Therapy indicates that DNA impurities derived from plasmid and host cell DNA are encapsulated into recombinant adeno-associated virus (rAAV) capsids as single-stranded DNA. Click here to read the article now.
rAAVs are widely used viral vectors in human gene therapy, but contamination from DNA impurities, such as plasmid and host cell DNA, remains a significant quality control concern for their manufacture. In this study, Kazuhisa Uchida, from Kobe University, and coauthors examined several purifies rAAV samples and found that they contained DNA derived from three plasmids. They determined that the impurities were encapsulated into the rAAV capsids as single-stranded DNA.
The investigators suggest that when rAAVs are used in gene therapy, the adverse effects of the single-stranded form of DNA impurities may differ from those of double-stranded DNA. “It may be necessary to reconsider or evaluate the effects of single-strand form of DNA impurities independently,” stated the investigators.
“Studies like this are incredibly important to better understand how DNA impurities are generated and what sources they come from during the production process in order to improve the efficiency of manufacturing and purity of the final rAAV product, which will help make the therapy more effective and reduce adverse events for patients,” says Managing Editor of Human Gene Therapy Thomas Gallagher, PhD, from the University of Massachusetts Chan Medical School.
European Parliament Event on Rare Disease Day +++
https://www.eurordis.org/european-parliament-rare-disease-day/
Impactofrarediseases:
https://download2.eurordis.org/REPORT_European_Parliament_event_on_RDD.pdf
Patient organisations warn against EU rollback on patient involvement in medicines regulation
https://www.eurordis.org/epf-eurordis-joint-statement-patient-involvement/
FDA approves first treatment for adults with complement 3 glomerulopathy, a rare kidney disease, to reduce proteinuria
https://www.fda.gov/drugs/news-events-human-drugs/fda-approves-first-treatment-adults-complement-3-glomerulopathy-rare-kidney-disease-reduce?utm_medium=email&utm_source=govdelivery
FDA Approves First Treatment for Adults with Complement 3 Glomerulopathy, a Rare Kidney Disease, to Reduce Proteinuria
FDA approved Fabhalta (iptacopan) for the treatment of adults with complement 3 glomerulopathy (C3G) to reduce proteinuria. Fabhalta is an oral capsule, taken twice daily. Recommended dosing is available in the prescribing information.
C3G is a rare disease that causes inflammation and damage to the kidney glomeruli, which are responsible for filtering blood and producing urine. In C3G, the complement system (proteins in the blood that play a critical role in the immune system) becomes abnormally activated. Complement products can become lodged in the glomeruli causing them to become leaky and harming their ability to filter blood. Waste products and toxins then build up in the blood, which decreases the kidneys’ ability to balance salts and minerals, decreases urine production, and causes continued kidney damage.
Fabhalta increases the risk of serious and life-threatening infections caused by encapsulated bacteria, including Streptococcus pneumoniae, Neisseria meningitidis, and Haemophilus influenzae type b. Patients should complete or update vaccination for encapsulated bacteria at least 2 weeks before the first dose of Fabhalta, unless the risks of delaying treatment outweigh the risks of developing a serious infection. Health care providers should monitor patients for early signs and symptoms of serious infections and evaluate immediately if infection is suspected.
Fabhalta may increase total cholesterol, LDL-cholesterol, and serum triglycerides. Health care providers should monitor patients’ serum lipid parameters periodically during treatment with Fabhalta and initiate cholesterol-lowering medication, if indicated.
Fabhalta is available only through a restricted program under a Risk Evaluation and Mitigation Strategy (REMS).
The most common adverse reactions (reported in at least 10% of patients) to Fabhalta were nasopharyngitis (common cold) and viral infections.
Study Illuminates the Structural Features of Memory Formation at the Cellular and Subcellular Levels NIH-funded study uses cutting-edge imaging techniques to reconstruct features underlying learning and memory in the mouse brain March 20, 2025 • Media Advisory
https://www.nimh.nih.gov/news/science-updates/2025/study-illuminates-the-structural-features-of-memory-formation-at-the-cellular-and-subcellular-levels
In a recent study funded by the National Institutes of Health (NIH), researchers shed new light on memory encoding.
The researchers exposed mice to a conditioning task and examined their hippocampus about one week later using cutting-edge technology such as 3-D electron microscopy and artificial intelligence.
Researchers discovered that neurons involved in memory formation were not preferentially connected. They also found that these neurons reorganized their connections through an atypical connection called a multi-synaptic bouton.
This study sheds new light on the fundamentally flexible nature of memory encoding and raises new questions and ideas for future exploration.
Read More Study Findings
jueves, 20 de marzo de 2025
Several kinds of acne products recalled over cancer risk, FDA says The recalled items include La Roche-Posay, Proactiv and Walgreens products Brie Stimson By Brie Stimson Fox News Published March 14, 2025 3:58pm EDT
Several kinds of acne products recalled over cancer risk, FDA says
The recalled items include La Roche-Posay, Proactiv and Walgreens products
Brie Stimson By Brie Stimson Fox News
Published March 14, 2025 3:58pm EDT
https://www.foxnews.com/health/several-kinds-acne-products-recalled-cancer-risk-fda-says
Deadly cancer type linked to obesity and high stress levels Healthy diet, exercise and mindfulness could reduce pancreatic cancer risk, study finds Melissa Rudy By Melissa Rudy Fox News Published March 15, 2025 5:17pm EDT
Deadly cancer type linked to obesity and high stress levels
Healthy diet, exercise and mindfulness could reduce pancreatic cancer risk, study finds
Melissa Rudy By Melissa Rudy Fox News
Published March 15, 2025 5:17pm EDT
https://www.foxnews.com/health/deadly-cancer-type-linked-obesity-high-stress-levels
Pain could be reduced by watching nature scenes, new study suggests Exposure to outdoor environments affects brain's pain centers, researchers say By Khloe Quill Fox News Published March 18, 2025 12:51pm EDT
Pain could be reduced by watching nature scenes, new study suggests
Exposure to outdoor environments affects brain's pain centers, researchers say
By Khloe Quill Fox News
Published March 18, 2025 12:51pm EDT
https://www.foxnews.com/health/pain-could-reduced-watching-nature-scenes-new-study-suggests
New outbreak of deadly bird flu strain confirmed for first time in 8 years The H7N9 strain was detected on a poultry farm in Mississippi Angelica Stabile By Angelica Stabile Fox News Published March 19, 2025 5:05pm EDT
New outbreak of deadly bird flu strain confirmed for first time in 8 years
The H7N9 strain was detected on a poultry farm in Mississippi
Angelica Stabile By Angelica Stabile Fox News
Published March 19, 2025 5:05pm EDT
https://www.foxnews.com/health/outbreak-deadly-bird-flu-strain-confirmed-first-time-8-years
Traveling amid measles, plus pet food recalls and cancer risk factors And more of the top Fox News Health stories and videos from the past week By Fox News Staff Fox News Published March 19, 2025 9:55pm EDT
Traveling amid measles, plus pet food recalls and cancer risk factors
And more of the top Fox News Health stories and videos from the past week
By Fox News Staff Fox News
Published March 19, 2025 9:55pm EDT
https://www.foxnews.com/health/traveling-amid-measles-outbreak-bird-flu-product-recalls-plus-cancer-linked-high-stress
Jillian Michaels reveals simple workout to extend your lifespan 'up to 7 years' 'Fitness is the No. 1 form of preventative medicine,' Michaels says Ashley J. DiMella By Ashley J. DiMella Fox News Published March 19, 2025 5:00am EDT
Jillian Michaels reveals simple workout to extend your lifespan 'up to 7 years'
'Fitness is the No. 1 form of preventative medicine,' Michaels says
Ashley J. DiMella By Ashley J. DiMella Fox News
Published March 19, 2025 5:00am EDT
https://www.foxnews.com/health/jillian-michaels-reveals-simple-workout-extend-lifespan-7-years
4 troubling cancer trends you must know about in 2025 Oncologists reveal the warning signs that most concern them this year Angelica Stabile By Angelica Stabile Fox News Published March 17, 2025 3:19pm EDT
4 troubling cancer trends you must know about in 2025
Oncologists reveal the warning signs that most concern them this year
Angelica Stabile By Angelica Stabile Fox News
Published March 17, 2025 3:19pm EDT
https://www.foxnews.com/health/4-troubling-cancer-trends-you-must-know-about-2025
Mother with rare ALS touts 'miracle drug' that has stopped her disease Since starting a clinical trial more than 7 years ago, Raziel Green says her symptoms have not gotten any worse Melissa Rudy By Melissa Rudy Fox News Published March 18, 2025 5:00am EDT
Mother with rare ALS touts 'miracle drug' that has stopped her disease
Since starting a clinical trial more than 7 years ago, Raziel Green says her symptoms have not gotten any worse
Melissa Rudy By Melissa Rudy Fox News
Published March 18, 2025 5:00am EDT
https://www.foxnews.com/health/mother-rare-als-touts-miracle-drug-has-stopped-her-disease
Cannabis use endangers heart health for certain group Marijuana impacts cardiac risk as soon as one hour after use, study finds Melissa Rudy By Melissa Rudy Fox News Published March 18, 2025 4:58pm EDT
Cannabis use endangers heart health for certain group
Marijuana impacts cardiac risk as soon as one hour after use, study finds
Melissa Rudy By Melissa Rudy Fox News
Published March 18, 2025 4:58pm EDT
https://www.foxnews.com/health/cannabis-use-endangers-heart-health-certain-group
Just 1 in 10 back pain treatments work, study says — what to do instead Pain is 'complex condition' that requires individual solutions, experts say Melissa Rudy By Melissa Rudy Fox News Published March 20, 2025 5:00am EDT
Just 1 in 10 back pain treatments work, study says — what to do instead
Pain is 'complex condition' that requires individual solutions, experts say
Melissa Rudy By Melissa Rudy Fox News
Published March 20, 2025 5:00am EDT
https://www.foxnews.com/health/just-1-10-back-pain-treatments-work-study-says-what-do-instead
A new vaccine is here to protect you and your loved ones from RSV this winter FDA approved a new vaccine for older adults and expanded approval for others
https://magazine.medlineplus.gov/article/a-new-vaccine-is-here-to-protect-you-and-your-loved-ones-from-rsv-this-winter
December and January are peak months for respiratory syncytial virus (RSV) infections. While anyone can get RSV, severe infections are more common in young children and older adults. Fortunately, new vaccine approvals by the U.S. Food and Drug Administration (FDA) mean there are more options to avoid getting sick this winter.
Parkinson’s disease explained What you need to know about this movement disorder
https://magazine.medlineplus.gov/article/parkinsons-disease-explained/
Parkinson's disease (PD) is a progressive movement disorder of the nervous system. PD is one of the most common nervous system disorders, especially among older adults. It’s estimated to affect between 500,000 and 1 million Americans.
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