CIENCIASMEDICASNEWS: enero 2025

viernes, 31 de enero de 2025

A long-awaited update on anxiety and antidepressants

https://www.statnews.com/2025/01/31/health-news-anxiety-antidepressants-rfk-jr-hearing-ebola-case-kampala-march-for-science-morning-rounds/

Uganda confirms Ebola case in nurse in capital city The case comes at a fragile time for global health, and as U.S.-WHO relations are strained

https://www.statnews.com/2025/01/30/uganda-ebola-sudan-nurse/?utm_campaign=morning_rounds&utm_medium=email&_hsenc=p2ANqtz-88C6W4WbGRbGioRcBSXXT1gSFouGu-eL2cvdeKmqUeXmTU91_4bd32tHqXWNfa_t0udJXnxRzK83Dg7bTgSn-5FvJAog&_hsmi=345022952&utm_content=345022952&utm_source=hs_email Ebola case confirmed in Uganda Ugandan health officials on Thursday confirmed a case of Ebola in the capital, Kampala, in a 32-year-old nurse. The man died Wednesday at the Mulago National Referral Hospital in Kampala. Officials identified 45 people who were in contact with the man; none have showed any signs of Ebola. Any Ebola outbreak raises fears of transmission, but an outbreak of the disease in an urban setting like Kampala raises particular concerns. The man was also infected with the Sudan strain of Ebola, for which there are no licensed therapeutics or vaccines. The news arrives three years after the country had an outbreak caused by Ebola Sudan that led to 164 cases, including 55 deaths. The confirmation of an Ebola case comes at a fragile time in global health. Under the new Trump administration, the U.S. is moving to withdraw from the World Health Organization and has already paused communications with WHO officials, steps that American and international health officials have widely decried and warned threaten global and U.S. health security. Read more here.

Vertex wins FDA approval for non-opioid pain drug, setting stage for closely watched rollout Analysts and pain experts have characterized the drug as modestly effective

https://www.statnews.com/2025/01/30/vertex-pain-drug-journavx-wins-fda-approval-non-opioid/

Antidepressants versus placebo for generalised anxiety disorder (GAD)

https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD012942.pub2/full?utm_campaign=morning_rounds&utm_medium=email&_hsenc=p2ANqtz-9PXDT7kmlKSNLDsF4mNG1p0o5RgTZ_7CVzO0DraewwonZv_8oVF-MTmrqKL-Tj-6gDjv64cgakZXz9amrYx1lXHkTKaQ&_hsmi=345022952&utm_content=345022952&utm_source=hs_email Anxiety and antidepressants Researchers confirmed that antidepressants lead to a significant reduction in generalized anxiety disorder symptoms in the short term. The long-awaited update, published by the Cochrane Database of Systematic Reviews, considered by some to be the gold-standard of evidence-based health care, considered evidence from 37 unique randomized control trials with 12,226 participants and found that these drugs are effective compared to a placebo. The drugs’ long-term impacts are muddier, said Prof. Peter Tyrer, an emeritus psychiatry professor at Imperial College London who was not involved in the study. Some patients have difficulties stopping antidepressants because of withdrawal problems. “The main reason why antidepressants were preferred to benzodiazepines (drugs that are equally effective in treating generalised anxiety) was the dependence risk, we just seem to have shifted the problem of adverse effects from one class of drugs to another,” Tyrer said.

Potentials of Presepsin as a Novel Sepsis Biomarker in Critically Ill Adults: Correlation Analysis with the Current Diagnostic Markers.

https://read.qxmd.com/read/39857101/potentials-of-presepsin-as-a-novel-sepsis-biomarker-in-critically-ill-adults-correlation-analysis-with-the-current-diagnostic-markers?uac=148436CN&ecd=wnl_readmost_250131&sso=true&redirected=slug

Associations of clinical parameter-based accelerated aging, genetic predisposition with risk of chronic kidney disease and associated life expectancy: A prospective cohort study.

https://read.qxmd.com/read/39717880/associations-of-clinical-parameter-based-accelerated-aging-genetic-predisposition-with-risk-of-chronic-kidney-disease-and-associated-life-expectancy-a-prospective-cohort-study?uac=148436CN&ecd=wnl_readmost_250131&sso=true&redirected=slug

Differential Organ Ageing Is Associated With Age-Related Macular Degeneration.

https://read.qxmd.com/read/39757747/differential-organ-ageing-is-associated-with-age-related-macular-degeneration?uac=148436CN&ecd=wnl_readmost_250131&sso=true&redirected=slug

Quinazolinone Derivative MR2938 Protects DSS-Induced Barrier Dysfunction in Mice Through Regulating Gut Microbiota.

https://read.qxmd.com/read/39861184/quinazolinone-derivative-mr2938-protects-dss-induced-barrier-dysfunction-in-mice-through-regulating-gut-microbiota?uac=148436CN&ecd=wnl_readmost_250131&sso=true&redirected=slug

Presentation and surgical management approaches of giant presacral and sacral schwannomas: a case report and systematic review and meta-analysis.

https://read.qxmd.com/read/39825133/presentation-and-surgical-management-approaches-of-giant-presacral-and-sacral-schwannomas-a-case-report-and-systematic-review-and-meta-analysis?uac=148436CN&ecd=wnl_readmost_250131&sso=true&redirected=slug

The present and future of the Cancer Dependency Map.

https://read.qxmd.com/read/39468210/the-present-and-future-of-the-cancer-dependency-map?uac=148436CN&ecd=wnl_readmost_250131&sso=true&redirected=slug

Recent advances in gut microbiota and thyroid disease: pathogenesis and therapeutics in autoimmune, neoplastic, and nodular conditions.

https://read.qxmd.com/read/39776440/recent-advances-in-gut-microbiota-and-thyroid-disease-pathogenesis-and-therapeutics-in-autoimmune-neoplastic-and-nodular-conditions?uac=148436CN&ecd=wnl_readmost_250131&sso=true&redirected=slug

SQYC formula improves the efficacy of PD-1 monoclonal antibodies in MSS colorectal cancer by regulating dendritic cell mitophagy via the PINK1-Parkin pathway.

https://read.qxmd.com/read/39826284/sqyc-formula-improves-the-efficacy-of-pd-1-monoclonal-antibodies-in-mss-colorectal-cancer-by-regulating-dendritic-cell-mitophagy-via-the-pink1-parkin-pathway?uac=148436CN&ecd=wnl_readmost_250131&sso=true&redirected=slug

LATEST GLP-1s: Good News, Bad News GLP-1s: Good News, Bad News F. Perry Wilson, MSCE, MD https://www.medscape.com/viewarticle/glp-1s-good-news-bad-news-2025a10001fm?ecd=mkm_ret_250131_mscpmrk-OUS_ICYMI_etid7192695&uac=148436CN&impID=7192695 RSV Vaccines Will Carry Neurologic Risk Warning RSV Vaccines Will Carry Warning for Guillain-Barré Syndrome Heidi Splete https://www.medscape.com/viewarticle/rsv-vaccines-will-carry-warning-guillain-barre-syndrome-2025a10001ia?ecd=mkm_ret_250131_mscpmrk-OUS_ICYMI_etid7192695&uac=148436CN&impID=7192695 January 22, 2025 Adult ADHD Diagnosis Linked to Earlier Death Adult ADHD Diagnosis Linked to Earlier Death Eve Bender https://www.medscape.com/viewarticle/adult-adhd-diagnosis-linked-earlier-death-2025a10001p8?ecd=mkm_ret_250131_mscpmrk-OUS_ICYMI_etid7192695&uac=148436CN&impID=7192695 January 23, 2025 Will Repurposing Meds Aid Dementia Prevention? Repurposing Meds for Dementia Prevention: Will it Work? Megan Brooks https://www.medscape.com/viewarticle/repurposing-meds-dementia-prevention-will-it-work-2025a10001m8?ecd=mkm_ret_250131_mscpmrk-OUS_ICYMI_etid7192695&uac=148436CN&impID=7192695 January 23, 2025 From around the world Ketamine-Induced Uropathy: What Urologists Need to Know Ketamine-Induced Uropathy: What Urologists Need to Know Vincent Richeux https://www.medscape.com/viewarticle/ketamine-induced-uropathy-what-urologists-need-know-2025a10001dp?ecd=mkm_ret_250131_mscpmrk-OUS_ICYMI_etid7192695&uac=148436CN&impID=7192695 January 21, 2025 PM1 Pollution Drives Respiratory Hospitalizations PM1 Pollution Drives Respiratory Hospitalizations Christina Ferrario https://www.medscape.com/viewarticle/pm1-pollution-drives-respiratory-hospitalizations-2025a10000wk?ecd=mkm_ret_250131_mscpmrk-OUS_ICYMI_etid7192695&uac=148436CN&impID=7192695 January 15, 2025 Innovations in HIV Care for Women Worldwide Innovations in HIV Care for Women Worldwide Débora M.G. Cunha https://www.medscape.com/viewarticle/innovations-hiv-care-women-worldwide-2025a10000s0?ecd=mkm_ret_250131_mscpmrk-OUS_ICYMI_etid7192695&uac=148436CN&impID=7192695 January 14, 2025

Growing Evidence Suggests Plant-Based Diets Reduce Cancer Risk Tara Haelle January 16, 2025 +++ ++++ ++

Novel Anti-CTGF Antibody Plus Chemotherapy Shows No Survival Benefit in Locally Advanced Pancreatic Cancer Christos Evangelou, MSc, PhD January 29, 2025

https://www.medscape.com/viewarticle/novel-anti-ctgf-antibody-plus-chemotherapy-shows-no-survival-2025a100027u

Postoperative RT Plus Cetuximab Showed Mixed Results in Head and Neck Cancer Trial Edited by Katie Lennon January 30, 2025

https://www.medscape.com/viewarticle/postoperative-rt-plus-cetuximab-showed-mixed-results-head-2025a10002e0

Fever of Unknown Origin in a Patient With No Recent History of Travel Joel Hamm, MD, MPH https://reference.medscape.com/viewarticle/1001853?ecd=mkm_ret_250130_mscpmrk-OUS_2AngDiscussions_etid7192512&uac=148436CN&impID=7192512 A Young Man With Jaundice, Headache, and Fever With a Recent History of Travel Neil Khoury, MD https://reference.medscape.com/viewarticle/1001875?ecd=mkm_ret_250130_mscpmrk-OUS_2AngDiscussions_etid7192512&uac=148436CN&impID=7192512

The 20+ Safest Online Communities for Kids

https://www.websiteplanet.com/blog/safest-online-communities-for-kids/

miércoles, 29 de enero de 2025

An AI-powered tool monitors lung sounds An algorithm for counting wheezing sounds in real time offers a new way to diagnose and manage respiratory conditions.

https://www.drugdiscoverynews.com/an-ai-powered-tool-monitors-lung-sounds-15946?utm_campaign=DDN_Newsletter_Dose&utm_medium=email&_hsenc=p2ANqtz-868XpBNS51BXHTozPNf0k9wGw3BSl_9XbmRm_1eSiKecwYsRvhdoDg52gsTJftTyzJ_UnjQgP3EVAd5I1WboaWYDFflw&_hsmi=344585613&utm_content=344585613&utm_source=hs_email

A therapeutic target to keep asthmatic airways loose N-cadherins in smooth muscle cells play an important role in constricting bronchi, but inhibiting the protein could provide relief to patients with asthma.

https://www.drugdiscoverynews.com/a-therapeutic-target-to-keep-asthmatic-airways-loose-16211

Common mental disorder could shorten your life, study finds Those with ADHD found to have ‘significantly’ shorter life expectancy, but more research is needed Melissa Rudy By Melissa Rudy Fox News Published January 28, 2025 3:08pm EST

Common mental disorder could shorten your life, study finds Those with ADHD found to have ‘significantly’ shorter life expectancy, but more research is needed Melissa Rudy By Melissa Rudy Fox News Published January 28, 2025 3:08pm EST https://www.foxnews.com/health/common-mental-disorder-could-shorten-life-study-finds

Kansas City tuberculosis outbreak is largest in US history Experts call for more 'organized testing' to stop the spread Angelica Stabile By Angelica Stabile Fox News Published January 28, 2025 4:53pm EST

Kansas City tuberculosis outbreak is largest in US history Experts call for more 'organized testing' to stop the spread Angelica Stabile By Angelica Stabile Fox News Published January 28, 2025 4:53pm EST https://www.foxnews.com/health/kansas-city-tuberculosis-outbreak-becomes-largest-us

This disease kills more people than all cancers and accidents combined Heart disease remains the top cause of death in the US, major report states Melissa Rudy By Melissa Rudy Fox News Published January 29, 2025 4:30am EST

This disease kills more people than all cancers and accidents combined Heart disease remains the top cause of death in the US, major report states Melissa Rudy By Melissa Rudy Fox News Published January 29, 2025 4:30am EST https://www.foxnews.com/health/disease-kills-more-people-than-all-cancers-accidents-combined

As beverages aimed at kids boom, new guidelines recommend water and plain milk Plant-based milks typically don’t contain the same levels of nutrients as cow’s milk

https://www.statnews.com/2025/01/29/beverages-kids-guidelines-water-pasteurized-milk/

When your child can’t walk and it could be polio It’s something most Americans can’t imagine — but that could change

https://www.statnews.com/2025/01/29/polio-vaccines-rfk-jr-confirmation-hearing-india/

Adult bi-paternal offspring generated through direct modification of imprinted genes in mammals

https://www.cell.com/cell-stem-cell/fulltext/S1934-5909(25)00005-0?utm_campaign=morning_rounds&utm_medium=email&_hsenc=p2ANqtz-_sb7bubYg26slaJuOqlBDdC7TUs0xUg-ZawsZ1UXwb0ntR7cgy5frimgwuId7-pIvVGshrbLRnvoslkEDaGRwBjYO3gw&_hsmi=344625380&utm_content=344625380&utm_source=hs_email The first mice with two dads have reached adulthood There’s been so much news on the “chaos” beat this week that I just had to share this: Scientists in China have successfully engineered “bi-paternal” mice (those with two male parents) that have lived until adulthood, according to a study published yesterday in Cell Stem Cell. Previous attempts have been complicated due to genetic imprinting abnormalities that lead to defects, which the authors say is a major barrier to these types of experiments. But in this study, researchers individually modified 20 key imprinting genes using multiple different methods to combat that issue. It’s cool science (that MIT Technology Review explains in more detail) but don’t forget the caveats: These are mice, not humans, or even primates. Also: Most of these embryos didn’t even make it to birth — only seven mice made it that far out of 164 embryos. Not all of those seven made it to adulthood either, and those that did often had altered growth, a shortened lifespan, and were sterile. https://www.technologyreview.com/2025/01/28/1110613/mice-with-two-dads-crispr/?utm_campaign=morning_rounds&utm_medium=email&_hsenc=p2ANqtz-_Vbfz3cakm6LrKBZZ9sBJPW1nnLwoLloxm2d0UnsvUapPlbBk5CSa9Q3KjxnvlIcbf6f3w9L5h4skIae26pT8TrWUp5g&_hsmi=344625380&utm_content=344625380&utm_source=hs_email

Key Statistics for Cervical Cancer

https://www.cancer.org/cancer/types/cervical-cancer/about/key-statistics.html?utm_campaign=morning_rounds&utm_medium=email&_hsenc=p2ANqtz--FoYig1qQHneJmE5mFR-vJgtonzUbErYUpQAtIOFytMBonzTqxcQRFJUZQKhX6Mpp_Uv4mTc1O7uCLfOzbzH2al-KvuA&_hsmi=344625380&utm_content=344625380&utm_source=hs_email Why are cervical cancer death rates so bad in the Mississippi Delta? While politics over DEI are roiling Washington, work to end racial health disparities continues. This morning, the Southern Rural Black Women’s Initiative for Economic and Social Justice and Human Rights Watch released a report on the findings of 10 community health researchers who spent 18 months interviewing more than 150 women in the Mississippi Delta to understand the factors driving the area's inflated rates of cervical cancer, which are among the nation’s highest. The mortality rate for cervical cancer is 65% higher for Black women than white women. The report found that access to gynecological care was a major reason for the disparities. A cascade of factors are to blame, including Mississippi’s refusal to expand Medicaid through the ACA, which has contributed to rural hospital closures and helped fuel a shortage of OB-GYNs in the state. A lack of access to public transportation and racial discrimination from health providers also limited access, which led to less cancer screening and surgical treatment. Poor access to information on sexual and reproductive health, the report said, is another reason the state is ranked last in the nation in rates of uptake of the HPV vaccine which prevents cervical cancer. — Usha Lee McFarling https://www.statnews.com/2025/01/27/trump-dei-executive-order-quick-nih-funding-cuts/?utm_campaign=morning_rounds&utm_medium=email&_hsenc=p2ANqtz-9jcH9FqKZ1DUvcCQUqL4GgppGkZPJ_ZowpXG1YAT62eGbRAXlI8m5s-iro-blfjoFImmQhi5cEK7Uk9dH3hqNzOmzcKA&_hsmi=344625380&utm_content=344625380&utm_source=hs_email

January 28, 2025 Brain Function Outcomes of Recent and Lifetime Cannabis Use

https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2829657?guestAccessKey=f8f351db-7527-4a41-a8f8-7726890cbbc9&utm_term=012825&utm_campaign=ftm_links&utm_medium=referral&_hsenc=p2ANqtz-9WalvwIQ5fjRvk-YZSGQ-2hTXePZGkwhoMUe735rFDjgnMte_931ZmJukzLcc3JyDij7zoqM6V4BHOAImGH4nayjnI8Q&_hsmi=344625380&utm_content=tfl&utm_source=for_the_media How weed may affect brain function People who use a lot of cannabis over time may experience reduced brain activity in certain situations, according to a study published yesterday in JAMA Network Open. Between 2012 and 2015, researchers tested more than 1,000 people ages 22-36. About 63% of “heavy users” — meaning those who have used cannabis 1,000 times or more — in the study had lower amounts of brain activity during a task, such as solving a math problem, that tests one’s ability to remember other information. There were similar associations between recent cannabis use and poor performance on working memory tasks, but other functions like motor skills, reward processing, emotion, and language did not see the same effects. It’s the largest study yet focusing on cannabis and brain function, the study authors write. Still, even larger and long-term studies are needed to fully understand the effects that cannabis has on the brain.

Advancing care in cardiovascular, renal and metabolic diseases with holistic combination therapies

https://www.statnews.com/sponsor/2024/11/19/next-wave-cvrm-combination-therapies-aim-to-improve-health-outcomes/

Goodbye biopsies, non-invasive diagnostics for fatty liver disease are here Through academic, industry, and governmental partnerships, scientists validate and develop non-invasive diagnostics for non-alcoholic fatty liver disease. These tests are set to replace the invasive and risky gold standard: liver biopsy.

https://www.drugdiscoverynews.com/goodbye-biopsies-non-invasive-diagnostics-for-fatty-liver-disease-are-here-15406?utm_campaign=DDN_Newsletter_Dose&utm_medium=email&_hsenc=p2ANqtz--6O_DHTt7CYXQjDB_grCVu3wBCUVlE46-yeyOTwup6Bxjg_jTA3-dNqxI0OHlbTSlqF_Ds6VJBWAQmITk_JwRWPsE1Zg&_hsmi=344502375&utm_content=344502375&utm_source=hs_email

The eye offers a window into the liver Researchers transplanted liver spheroids into the corneas of mice to non-invasively image the liver.

https://www.drugdiscoverynews.com/the-eye-offers-a-window-into-the-liver-15963?utm_campaign=DDN_Newsletter_Dose&utm_medium=email&_hsenc=p2ANqtz-9s6RSvPsh1aHGpDAVKwoKijPYEXJoKQiULObtft8zo_S6NDBim-x8g2RYCsLYdHbRfqgqe27SAP-R20W4sQkKvrZoGlA&_hsmi=344502375&utm_content=344502375&utm_source=hs_email

Oral drug shows promise for severe fatty liver in Phase 2b trial Sagimet’s denifanstat delivered significant improvements in disease activity and fibrosis for patients with metabolic dysfunction-associated steatohepatitis.

https://www.drugdiscoverynews.com/oral-drug-shows-promise-for-severe-fatty-liver-in-phase-2b-trial-16209

Prescription Stimulant Dispensing to US Children: 2017–2023

https://publications.aap.org/pediatrics/article/doi/10.1542/peds.2024-068558/200682/Prescription-Stimulant-Dispensing-to-US-Children?&utm_campaign=morning_rounds&utm_medium=email&_hsenc=p2ANqtz-8nJL6tYLG-4WPjC2ZfZRv4zT2ehqGmaWTzFJ5GX7-8hLGGKprchbkL1zJKeKUPtnPhdCo3zVqijWS6osBHobl_2OE-QQ&_hsmi=344409238&utm_content=344409238&utm_source=hs_email?autologincheck=redirected Kids with ADHD and the Adderall shortage In Oct. 2022, the FDA announced a shortage of Adderall, the go-to treatment for ADHD. Since then, an increasing number of kids have gotten prescriptions for other stimulants, according to a study published yesterday in Pediatrics. The dip in Adderall prescriptions has been offset by an increase for a drug called Focalin. Researchers analyzed trends in the dispensation of stimulants to kids ages 5 to 17 between 2017 and 2023. Prescriptions declined in the beginning of the pandemic, but they’ve slowly climbed back up to normal, with a few exceptions. Most notably, in December 2023, girls aged 11 and younger had a monthly stimulant-dispensing rate that was 9% higher than pre-pandemic trends predicted. This likely doesn’t mean that more girls have ADHD than before, but perhaps signals that the condition isn’t going undiagnosed in girls as often as it used to. (In the last days of the Biden administration, the DEA proposed a long-awaited special registration process for prescribers who want to provide controlled substances like Adderall via telehealth. It’s unclear how the Trump administration will move forward on the rule.) https://www.statnews.com/2025/01/15/telehealth-adderall-buprenorphine-dea-rules/?utm_campaign=morning_rounds&utm_medium=email&_hsenc=p2ANqtz-828Q8ChlapSEVkD79TAiKPxjP8xUllfzED_-5UtujRqt-dIe4caZ8G-EGByJZh26r7mnMqgUmvfJ6d81CCuHQsrGp3bw&_hsmi=344409238&utm_content=344409238&utm_source=hs_email

My view on maternal-fetal care: Pregnant people deserve medicines that fight as hard as they do

https://www.statnews.com/sponsor/2024/12/02/my-view-on-maternal-fetal-care-pregnant-people-deserve-medicines-that-fight-as-hard-as-they-do/

Has a ‘quademic’ hit the US? 4 viral infections and what to know about them Doctors break down the risks of flu, COVID, RSV and norovirus Melissa Rudy By Melissa Rudy Fox News Published January 22, 2025 4:30am EST

Has a ‘quademic’ hit the US? 4 viral infections and what to know about them Doctors break down the risks of flu, COVID, RSV and norovirus Melissa Rudy By Melissa Rudy Fox News Published January 22, 2025 4:30am EST https://www.foxnews.com/health/has-quademic-hit-us-viral-infections-what-know-about-them

Brain and memory are boosted by eating one particular diet, study finds Certain foods were shown to strengthen cognitive health through changes in the gut Angelica Stabile By Angelica Stabile Fox News Published January 24, 2025 4:30am EST

Brain and memory are boosted by eating one particular diet, study finds Certain foods were shown to strengthen cognitive health through changes in the gut Angelica Stabile By Angelica Stabile Fox News Published January 24, 2025 4:30am EST https://www.foxnews.com/health/brain-memory-boosted-eating-one-particular-diet-study-finds

Memory loss isn’t always Alzheimer’s: Experts warn of common but little-known dementia Symptoms of ‘LATE’ mimic Alzheimer’s, but prognosis is different Melissa Rudy By Melissa Rudy Fox News Published January 23, 2025 6:00pm EST | Updated January 23, 2025 5:45pm EST

Memory loss isn’t always Alzheimer’s: Experts warn of common but little-known dementia Symptoms of ‘LATE’ mimic Alzheimer’s, but prognosis is different Melissa Rudy By Melissa Rudy Fox News Published January 23, 2025 6:00pm EST | Updated January 23, 2025 5:45pm EST https://www.foxnews.com/health/memory-loss-isnt-always-alzheimers-experts-warn-common-little-known-dementia

Kelly Ripa says quitting alcohol had a surprising effect on her weight Health expert explains why eliminating drinking can cause weight fluctuations Angelica Stabile By Angelica Stabile Fox News Published January 24, 2025 4:00pm EST

Kelly Ripa says quitting alcohol had a surprising effect on her weight Health expert explains why eliminating drinking can cause weight fluctuations Angelica Stabile By Angelica Stabile Fox News Published January 24, 2025 4:00pm EST https://www.foxnews.com/health/kelly-ripa-says-quitting-alcohol-had-surprising-effect-her-weight

Alcohol poses these 8 risks to older adults, experts warn Heavy alcohol use has been linked to increased risk of dementia, cancer and more By Amy McGorry Fox News Published January 25, 2025 4:30am EST

Alcohol poses these 8 risks to older adults, experts warn Heavy alcohol use has been linked to increased risk of dementia, cancer and more By Amy McGorry Fox News Published January 25, 2025 4:30am EST https://www.foxnews.com/health/alcohol-poses-risks-older-adults-experts-warn

Alabama woman who is only person in the world with a functioning pig organ reaches record 2-month milestone Towana Looney, 53, has surpassed two months with her pig kidney Landon Mion By Landon Mion Fox News Published January 26, 2025 3:11am EST

Alabama woman who is only person in the world with a functioning pig organ reaches record 2-month milestone Towana Looney, 53, has surpassed two months with her pig kidney Landon Mion By Landon Mion Fox News Published January 26, 2025 3:11am EST https://www.foxnews.com/health/alabama-woman-who-only-person-world-functioning-pig-organ-reaches-record-2-month-milestone

Feeling extra tired? This virus could be the culprit, study suggests Cases of chronic fatigue syndrome are 15 times higher than pre-pandemic Melissa Rudy By Melissa Rudy Fox News Published January 26, 2025 4:30am EST

Feeling extra tired? This virus could be the culprit, study suggests Cases of chronic fatigue syndrome are 15 times higher than pre-pandemic Melissa Rudy By Melissa Rudy Fox News Published January 26, 2025 4:30am EST https://www.foxnews.com/health/feeling-extra-tired-virus-could-culprit-study-suggests

Red meat could raise dementia risk, researchers claim, yet some doctors have questions Study suggests processed meats accelerate brain aging while some warn of potential bias Melissa Rudy By Melissa Rudy Fox News Published January 27, 2025 4:30am EST

Red meat could raise dementia risk, researchers claim, yet some doctors have questions Study suggests processed meats accelerate brain aging while some warn of potential bias Melissa Rudy By Melissa Rudy Fox News Published January 27, 2025 4:30am EST https://www.foxnews.com/health/red-meat-could-raise-dementia-risk-researchers-claim-some-doctors-question

WWII veteran turns 100, reveals the secrets of a long, healthy life 'Start each day with a fixed goal, such as a long walk' By Maureen Mackey Fox News Published January 27, 2025 12:45pm EST

WWII veteran turns 100, reveals the secrets of a long, healthy life 'Start each day with a fixed goal, such as a long walk' By Maureen Mackey Fox News Published January 27, 2025 12:45pm EST https://www.foxnews.com/health/wwii-veteran-turns-100-reveals-secrets-long-healthy-life

Drinking sparkling water could have surprising impact on weight, study suggests Carbonated water can lead to fullness and reduced caloric intake, researchers say Angelica Stabile By Angelica Stabile Fox News Published January 27, 2025 3:55pm EST

Drinking sparkling water could have surprising impact on weight, study suggests Carbonated water can lead to fullness and reduced caloric intake, researchers say Angelica Stabile By Angelica Stabile Fox News Published January 27, 2025 3:55pm EST https://www.foxnews.com/health/drinking-sparkling-water-could-have-surprising-impact-weight-study-suggests

RFK Jr. likely to be confirmed as health secretary, Dr. Siegel says 'He's going to get in,' doctor predicts on 'Fox & Friends' Angelica Stabile By Angelica Stabile Fox News Published January 27, 2025 5:19pm EST

RFK Jr. likely to be confirmed as health secretary, Dr. Siegel says 'He's going to get in,' doctor predicts on 'Fox & Friends' Angelica Stabile By Angelica Stabile Fox News Published January 27, 2025 5:19pm EST https://www.foxnews.com/health/rfk-jr-likely-confirmed-health-secretary-dr-siegel-says

Bill Gates likely had autism as a child, he reveals: ‘Wasn’t widely understood’ The disorder was largely 'off the radar' in the '50s and '60s, experts say Melissa Rudy By Melissa Rudy Fox News Published January 28, 2025 4:30am EST

Bill Gates likely had autism as a child, he reveals: ‘Wasn’t widely understood’ The disorder was largely 'off the radar' in the '50s and '60s, experts say Melissa Rudy By Melissa Rudy Fox News Published January 28, 2025 4:30am EST https://www.foxnews.com/health/bill-gates-likely-had-autism-child-reveals-wasnt-widely-understood

Who is protecting Americans from Marburg right now? The U.S. had a playbook — now undermined — for responding to biological threats

https://www.statnews.com/2025/01/27/marburg-virus-ebola-who-cdc/

Veru says its drug preserved lean mass in patients taking Wegovy Some experts were skeptical the results support benefits of the drug, called enobosarm

https://www.statnews.com/2025/01/27/veru-enobosarm-wegovy-obesity-lean-mass-muscle/

Akero drug reverses liver scarring in study of severe MASH patients Patients with cirrhosis due to MASH have a severe form of the disease with few treatment options outside of a liver transplant

https://www.statnews.com/2025/01/27/akero-efruxifermin-liver-fibrosis-mash/

Bariatric surgery halted progression of liver disease in patients with obesity and cirrhosis, study finds ‘We can change the trajectory of the disease’

https://www.statnews.com/2025/01/27/bariatric-surgery-cirrhosis-liver-disease/?utm_campaign=morning_rounds&utm_medium=email&_hsenc=p2ANqtz-8fRLFzt1Hi-kOuxb2zCBWnaF2bbtOT5iyL09p_xuebmtE4EsQ8r2ePN0SumKD0folVrbFuSFfVgOtgo-epk2y98XjXqA&_hsmi=344205424&utm_content=344205424&utm_source=hs_email Could bariatric surgery help treat liver disease? For people with obesity and cirrhosis, a late stage of liver disease, one new, small study says that bariatric surgery might be an option. The study, published today in Nature Medicine, followed 168 patients, about a third of whom underwent bariatric surgery. After 15 years, fewer people in the surgical group developed one of the major complications of liver disease, which include cancer and death, than in the non-surgical group. “We can change the trajectory of the disease,” Ali Aminian, a co-author on the study, told STAT’s Liz Cooney. Read more on the specifics.

State of the Heart (and Brain) in 2025

https://www.ahajournals.org/doi/10.1161/CIRCULATIONAHA.125.073826?utm_campaign=morning_rounds&utm_medium=email&_hsenc=p2ANqtz-_FUgukJCJosv4sJCs0bCYivchKaojOuqFQNGruYMr7qEzMbhnEYYXib-WAwr3-7vs6guypuvaUhpbDagOolJOuDjkLLA&_hsmi=344205424&utm_content=344205424&utm_source=hs_email Heart disease is still the biggest killer In 2022, about 40% of deaths in the U.S. were caused by cardiovascular heart disease, including heart disease and stroke, which kill more people in the U.S. than the next two biggest killers — all forms of cancer and accidental deaths — combined. That’s according to an annual update from the American Heart Association on heart disease and stroke statistics, published today in Circulation. Cardiovascular disease is “common, catastrophic, and costly,” an accompanying editorial notes. Despite its dominance, the overall number of deaths is leveling out after the pandemic shot numbers upwards. Yet contributing risk factors like high blood pressure and obesity continue to rise. Here are some more interesting findings: The percentage of high schoolers who are physically active for over an hour every day decreased from almost 29% to just under 24% between 2011 to 2021. Nearly 47% of all Americans have high blood pressure. In 2022, the prevalence was worst in Mississippi at about 40% and best in Colorado, at just under 25%. The rate of gestational diabetes in the U.S. increased 38% from 2016 to 2021, to 8.3% of pregnancies. https://www.ahajournals.org/journal/circ?utm_campaign=morning_rounds&utm_medium=email&_hsenc=p2ANqtz--ygkV5trH0Cbfrt3-hi7r76or309VrIG3Tz_Gv-6ikM6wPFA-WJnn6Hr7QxevLFYb-3PrlCRzNG_vq_xoESrWwJl6yNg&_hsmi=344205424&utm_content=344205424&utm_source=hs_email

Bringing the curative potential of CAR T-cell therapy to more eligible patients

https://www.statnews.com/sponsor/2025/01/10/bringing-the-curative-potential-of-car-t-cell-therapy-to-more-eligible-patients/

To block dengue, humans and mosquitoes could share antivirals A compound that inhibits replication of the dengue virus in mammals was similarly effective in mosquitoes consuming it via blood, reducing transmissibility. ++++

https://www.drugdiscoverynews.com/to-block-dengue-humans-and-mosquitoes-could-share-antivirals-16207 Boosting ovarian cancer immunotherapy with fatty acid uptake Ovarian tumors are extremely difficult to get rid of. Scientists are figuring out how to leverage the immune system to help. https://www.drugdiscoverynews.com/boosting-ovarian-cancer-immunotherapy-with-fatty-acid-uptake-16205 Immunotherapy boosts chemotherapy in rare urological cancers An immune checkpoint inhibitor and chemotherapy extended progression-free survival in late-stage small cell bladder and prostate cancers. https://www.drugdiscoverynews.com/immunotherapy-boosts-chemotherapy-in-rare-urological-cancers-16203 WHAT IS MESENCHYMAL STEM CELL THERAPY? https://www.drugdiscoverynews.com/what-is-mesenchymal-stem-cell-therapy-16153

Apixaban versus aspirin for stroke prevention in people with subclinical atrial fibrillation and a history of stroke or transient ischaemic attack: subgroup analysis of the ARTESiA randomised controlled trial

https://www.thelancet.com/collections/neurology?dgcid=hubspot_email_infocusalerts-neurology_feature&parent=001585&startPage=&ContentItemType=fla&utm_campaign=infocusalerts-neurology&utm_medium=email&_hsenc=p2ANqtz-84_fwuNvty3Sry-3b5wKrjkUT6CCUrKNZaglOkpHwNPEwh3NvkNQtGZDom44pIwsL55XpRxSW1bfuAKFVpCtCRV9luKg&_hsmi=344019965&utm_content=343601522&utm_source=hs_email

‘Alarming Disparities’ in Cancer Trends and Shift to Women, Younger Adults Richard Mark Kirkner January 17, 2025 +++ ++++ +++

What do we mean by evidence? How choosing the right methods can improve the real-world relevance of mental health research

IAMHRF Online Symposium: What do we mean by evidence?, inspired by The Lancet Psychiatry’s Commission on Transforming Mental Health Implementation Research. Feb 6, 2024, 1:30 PM GMT / 8:30 AM ET. https://events.teams.microsoft.com/event/d1fd5400-eaad-4123-9cbe-addf8b108d2d@91a138ee-d6db-40d9-9ca7-44fcd132fa5e

Psychological interventions to prevent the onset of major depression in adults: a systematic review and individual participant data meta-analysis

https://www.thelancet.com/journals/lanpsy/article/PIIS2215-0366(24)00316-X/fulltext?dgcid=hubspot_email_infocusalerts-psychiatry_feature&utm_campaign=infocusalerts-psychiatry&utm_medium=email&_hsenc=p2ANqtz-8AznZcCSVS8T3m_xH33g8R-A8QmCJNcH6zXA7t-S_6fEqdnyidj5qvPr4PxBsZhyHFsWihJh6NY8B9wMhouGaKByM12w&_hsmi=344118207&utm_content=343602217&utm_source=hs_email

Effectiveness and cost-effectiveness of online recorded recovery narratives in improving quality of life for people with psychosis experience (NEON Trial): a pragmatic randomised controlled trial

https://www.thelancet.com/journals/lanepe/article/PIIS2666-7762(24)00268-0/fulltext?dgcid=hubspot_email_infocusalerts-psychiatry_feature&utm_campaign=infocusalerts-psychiatry&utm_medium=email&_hsenc=p2ANqtz--6_WFzITKQXDiDmPyVhCZKTdzAGturGnIMdRMjtMXR1MWJK0adLLZdzMTdxhWSpswD_yvHDdStwMN6xExyJdJ2mrBcpQ&_hsmi=344118207&utm_content=343602217&utm_source=hs_email

Intranasal oxytocin for apathy in people with frontotemporal dementia (FOXY): a multicentre, randomised, double-blind, placebo-controlled, adaptive, crossover, phase 2a/2b superiority trial

https://www.thelancet.com/collections/psychiatry?dgcid=hubspot_email_infocusalerts-psychiatry_feature%20&parent=001633&startPage=&ContentItemType=fla&utm_campaign=infocusalerts-psychiatry&utm_medium=email&_hsenc=p2ANqtz-8bARN9A33qLsCBDsqeRd39ofi6CuxpHjxgbLWszhNpSArUiY6IB7NaFjppOJ3sCrFMMXlbLfQl6Jel1_mUrb7VKiw8sw&_hsmi=344118207&utm_content=343602217&utm_source=hs_email

Urinary Metals Linked to Increased Dementia Risk Edited by Anushree Chaphalkar +++ +++ ++

Microdosing Ozempic and other GLP-1 drugs to save money and reduce side effects is a hot fad. Does it work? Shiv Sudhakar | Fox News | January 24, 2025

https://geneticliteracyproject.org/2025/01/24/microdosing-ozempic-and-other-glp-1-drugs-to-save-money-and-reduce-side-effects-is-a-hot-fad-does-it-work/?mc_cid=1a5e8f3963&mc_eid=b73600b7ac

Novo Nordisk’s next-generation obesity treatment shows promise in early study The study tested an injectable form of the drug, amycretin. Novo is also developing a pill form

https://www.statnews.com/2025/01/24/novo-nordisk-amycretin-injectable-trial-wegovy/?utm_campaign=daily_recap&utm_medium=email&_hsenc=p2ANqtz--Z85rg6FzUw1hApF760R_YzmIDj1ie_7Ff8Soc_cAMNIor4dS6m-dWYqMMjcmyeR2zYoFs3_3ixwLAzRQEt9E2Skw3dw&_hsmi=344051288&utm_content=344051288&utm_source=hs_email

Role of Allogeneic Hematopoietic Stem Cell Transplantation for Philadelphia Chromosome-Positive B-Cell Acute Lymphoblastic Leukemia in the Contemporary Era.

https://read.qxmd.com/read/39796731/role-of-allogeneic-hematopoietic-stem-cell-transplantation-for-philadelphia-chromosome-positive-b-cell-acute-lymphoblastic-leukemia-in-the-contemporary-era?uac=148436CN&ecd=wnl_readmost_250124&sso=true&redirected=slug

Eating disorders in young people linked to genetics and delayed brain maturation Milly Remmington | Neuroscience News | January 22, 2025

https://geneticliteracyproject.org/2025/01/22/eating-disorders-in-young-people-linked-to-genetics-and-delayed-brain-maturation/?mc_cid=905341e13f&mc_eid=b73600b7ac

SKIN & INFLAMMATORY CONDITIONS Key Target for Seborrheic Dermatitis Highlighted Inflammation Now the Key Target for Seborrheic Dermatitis Ted Bosworth https://www.medscape.com/viewarticle/inflammation-now-key-target-seborrheic-dermatitis-2025a100005x?ecd=mkm_ret_250124_mscpmrk_allergy_top-content_etid7181790&uac=148436CN&impID=7181790 January 06, 2025 Allergic Contact Dermatitis: New Culprits Allergic Contact Dermatitis: New Culprits Stéphanie Lavaud https://www.medscape.com/viewarticle/allergic-contact-dermatitis-new-culprits-2024a1000ok0?ecd=mkm_ret_250124_mscpmrk_allergy_top-content_etid7181790&uac=148436CN&impID=7181790 Topical Ruxolitinib: Practice Essential ruxolitinib topical (Rx) https://reference.medscape.com/drug/opzelura-ruxolitinib-topical-4000177?ecd=mkm_ret_250124_mscpmrk_allergy_top-content_etid7181790&uac=148436CN&impID=7181790 Long-Term Budesonide Shows Sustained Efficacy in EoE Long-Term Budesonide Shows Sustained Efficacy in Eosinophilic Esophagitis Edited by Vinod Rane https://www.medscape.com/viewarticle/long-term-budesonide-shows-sustained-efficacy-eosinophilic-2025a10000jk?ecd=mkm_ret_250124_mscpmrk_allergy_top-content_etid7181790&uac=148436CN&impID=7181790 January 10, 2025

ALLERGIES & RESPIRATORY ISSUES: Alpha-Gal Syndrome: 5 Things to Know Gilbert Kersh, PhD ++++

ALLERGIES & RESPIRATORY ISSUES Alpha-Gal Syndrome: 5 Things to Know Alpha-Gal Syndrome: 5 Things to Know Gilbert Kersh, PhD https://www.medscape.com/viewarticle/alpha-gal-syndrome-5-things-know-2024a1000my2?ecd=mkm_ret_250124_mscpmrk_allergy_top-content_etid7181790&uac=148436CN&impID=7181790 Early-Onset Asthma Linked to Memory Early-Onset Asthma May Slow Memory Development Heidi Splete https://www.medscape.com/viewarticle/early-onset-asthma-may-slow-memory-development-2025a10000sc?ecd=mkm_ret_250124_mscpmrk_allergy_top-content_etid7181790&uac=148436CN&impID=7181790 January 14, 2025 What Are Best Treatments for Rhinitis? Rapid Rx Quiz Treating Rhinitis Praveen Buddiga, MD https://reference.medscape.com/viewarticle/1001929?ecd=mkm_ret_250124_mscpmrk_allergy_top-content_etid7181790&uac=148436CN&impID=7181790 First New Tx in 50 Yrs for Serious Asthma Attack First New Treatment in 50 Years for Serious Asthma Attacks https://www.medscape.co.uk/s/viewarticle/first-new-treatment-50-years-serious-asthma-attacks-2024a1000lma?ecd=mkm_ret_250124_mscpmrk_allergy_top-content_etid7181790&uac=148436CN&impID=7181790&sso=true

Exercise & Brain Health | Tribal Alcohol Intervention | Promising Medical Findings | DASH Eating Plan | Endocrine Disruptors

https://content.govdelivery.com/accounts/USNIH/bulletins/3ccbc3e?reqfrom=share

jueves, 23 de enero de 2025

Resources for People with Living a Serious Illness Affected by the California Wildfires

https://getpalliativecare.org/resources-for-people-with-a-serious-illness-affected-by-the-california-wildfires/?utm_source=Get+Palliative+Care&utm_campaign=b11c5b5b75-GPC+%2F+1.23.25&utm_medium=email&utm_term=0_4ef32a103e-b11c5b5b75-378264050 Palliative Care Provider Directory https://getpalliativecare.org/provider-directory/?utm_source=Get+Palliative+Care&utm_campaign=b11c5b5b75-GPC+%2F+1.23.25&utm_medium=email&utm_term=0_4ef32a103e-b11c5b5b75-378264050

Rare gene variants may influence reproductive age and cancer risk Profiling over 100,000 genomes, researchers identified rare mutations associated with early menopause and cancer, and that some mutations pass down to children.

https://www.drugdiscoverynews.com/rare-gene-variants-may-influence-reproductive-age-and-cancer-risk-16109?utm_campaign=DDN_Newsletter_Dose&utm_medium=email&_hsenc=p2ANqtz-8wdpmlMjBHnFA6h2u5QBZ__JXUwHvGaX9tNW0q8OUY-x9em8FGim5qiP9G9ezlR01wZ-E33byO1ZxVNqCC2yhedJ7BMA&_hsmi=343825652&utm_content=343825652&utm_source=hs_email

Boosting ovarian cancer immunotherapy with fatty acid uptake Ovarian tumors are extremely difficult to get rid of. Scientists are figuring out how to leverage the immune system to help.

https://www.drugdiscoverynews.com/boosting-ovarian-cancer-immunotherapy-with-fatty-acid-uptake-16205

FDA adds Boxed Warning about a rare but serious allergic reaction called anaphylaxis with the multiple sclerosis medicine glatiramer acetate (Copaxone, Glatopa)

https://www.fda.gov/drugs/drug-safety-and-availability/fda-adds-boxed-warning-about-rare-serious-allergic-reaction-called-anaphylaxis-multiple-sclerosis?utm_medium=email&utm_source=govdelivery

Viewpoint: Are warnings on alcoholic drinks necessary? Will they save lives? Devon Frye | Psychology Today | January 21, 2025

https://geneticliteracyproject.org/2025/01/21/viewpoint-are-warnings-on-alcoholic-drinks-necessary-will-they-save-lives/?mc_cid=bc8fb195ce&mc_eid=b73600b7ac

One out of three people are likely to develop dementia as they age. Here are 15 ways science can help slow or prevent the process Marlene Cimons | Washington Post | January 22, 2025

https://geneticliteracyproject.org/2025/01/22/one-out-of-three-people-are-likely-to-develop-dementia-as-they-age-here-are-15-ways-science-can-help-slow-or-prevent-the-process/?mc_cid=bc8fb195ce&mc_eid=b73600b7ac

Eating disorders in young people linked to genetics and delayed brain maturation Milly Remmington | Neuroscience News | January 22, 2025

https://geneticliteracyproject.org/2025/01/22/eating-disorders-in-young-people-linked-to-genetics-and-delayed-brain-maturation/?mc_cid=bc8fb195ce&mc_eid=b73600b7ac

miércoles, 22 de enero de 2025

Efficacy and safety of tezepelumab versus placebo in adults with moderate to very severe chronic obstructive pulmonary disease (COURSE): a randomised, placebo-controlled, phase 2a trial

https://www.thelancet.com/journals/lanres/article/PIIS2213-2600(24)00324-2/abstract?utm_campaign=update-lanres&utm_medium=email&dgcid=hubspot_update_feature_updatealerts_lanres&_hsenc=p2ANqtz-_gBmTdXk_9uHKBtb8vgFgxpgR6a77A5EpkQAhfcsnBGj6Zm9NqFJaEjk7f1jrqcUPk2UuADstb9Z7P_-wOSpSaBhQdvw&_hsmi=343282117&utm_content=343275138&utm_source=hs_email

The UK Tobacco and Vapes Bill: a historic opportunity The Lancet Respiratory Medicine

https://www.thelancet.com/journals/lanres/issue/vol13no1/PIIS2213-2600(24)X0013-2

Immunotherapy boosts chemotherapy in rare urological cancers An immune checkpoint inhibitor and chemotherapy extended progression-free survival in late-stage small cell bladder and prostate cancers.

https://www.drugdiscoverynews.com/immunotherapy-boosts-chemotherapy-in-rare-urological-cancers-16203

Final sale: my eight-year struggle to return recalled breast implants After a voluntary double mastectomy, I learned that my implants put me at risk of lymphoma — and no one would remove them

https://www.statnews.com/2025/01/21/allergan-natrelle-breast-implants-recall-fda-lymphoma/?utm_campaign=morning_rounds&utm_medium=email&_hsenc=p2ANqtz--wVG1oYJdhvaynMc13ng8GHKritRCkoZ-xqBy2JXWwpWDDnzzDR00Kdz4CfdfGf55_3Ge8EF38qCMQc0kPOAvP04oVBA&_hsmi=343359550&utm_content=343359550&utm_source=hs_email How she finally got a ticking time bomb out of her body We have a ton of news to digest today, but make room for this First Opinion. Oceana Callum tells a haunting and horrifying story of living with breast implants after cancer treatment that were later voluntarily recalled because they were linked to another form of cancer. No surgeon would agree to remove them unless she actually developed lymphoma, a decision supported by the FDA. Insurers have to cover breast reconstruction, for its mental health and other benefits, but not implant removal. “For many cancer survivors, potentially carcinogenic implant removal is, obviously, integral to our peace of mind,” Callum writes. “Having a ticking time bomb in one’s body is, ironically, to be imprisoned in the same situation from which many of us struggled brutally to be freed.” Read how she got out.

Alcohol labels should carry ‘Alcohol Facts’ box listing nutrition and allergens, regulator says The Alcohol and Tobacco Tax and Trade Bureau’s proposal follows years of consumer petitioning

https://www.statnews.com/2025/01/17/nutrition-fact-labels-on-alcoholic-beverages-treasury-department-proposed-new-rule/?utm_campaign=morning_rounds&utm_medium=email&_hsenc=p2ANqtz-8UGMlQd9qoo1YGHscgI0Rd__rsHY0zLQnBgjXxi3DvecwDvI1Wz6Qmv47f7diVCbgvQms4JYqzbGxtCwlJmPlhllmM7A&_hsmi=343359550&utm_content=343359550&utm_source=hs_email Do numbers on a label work to help people make healthier choices? Two approaches: You’re familiar with the nutrition box for food labels. Now it’s alcohol’s turn. The Alcohol and Tobacco Tax and Trade Bureau has proposed requiring companies to disclose alcohol content and any major food allergens. Information boxes would list the alcohol content of a drink, in fluid ounces of pure alcohol per serving, as well as the familiar calories, carbohydrates, protein, and fats. What took so long? The FDA rules over food, while the Alcohol and Tobacco Tax and Trade Bureau (an agency within the U.S. Treasury) rules over, well, alcohol. STAT’s Isabella Cueto tells us more. Calorie counts on menus for foods you order have been around since 2018, when the FDA ordered chain restaurants to display them, and in the U.K. since 2022, when regulators there introduced the same rule. The Cochrane Collaborative concludes after its hallmark systematic review that the benefits are pretty slim, possibly leading diners to choose foods with an average 1.8% fewer calories than they would without calorie labels. But it’s not nothing, STAT’s Sarah Todd learned. Do calorie counts on menus really change how people eat? Calorie labels on menus have a small but meaningful impact on people’s choices, review finds https://www.statnews.com/2025/01/16/calorie-counts-on-menus-effects-on-choices-cochrane-review/?utm_campaign=morning_rounds&utm_medium=email&_hsenc=p2ANqtz-_19lHCGT6j68WmJuoWVkHy9H0rwsB1SyqEgcaJqPzP6O5w7ecmhDs4FSRghoPGpE9eAwnbkK9Hc28dXr37INTTn5C9Ew&_hsmi=343359550&utm_content=343359550&utm_source=hs_email

Mapping the effectiveness and risks of GLP-1 receptor agonists

https://www.nature.com/articles/s41591-024-03412-w What can’t GLP-1 drugs do? Ziyad Al-Aly led a team trying to compile what he calls an atlas of risks and benefits from the obesity drugs. You’ve heard of health benefits linked to weight loss, like better heart health or diabetes control (the original intent). You may also know people feel the pull of addiction to alcohol or other drugs isn’t so strong. In a large study of VA patients, a new paper out in Nature Medicine Monday found 42 benefits but 19 harms, some of them not familiar. “We tend to think of drugs sort of like they are surgically designed to do only one thing. But the reality is it's almost never like this,” Al-Aly explained. I have more here. What can’t GLP-1s do? Study maps benefits while warning of uncommon risks Atlas of good and bad effects aims to close knowledge gap for blockbuster obesity drugs https://www.statnews.com/2025/01/20/glp-1-drugs-more-than-weight-loss-new-study-42-possible-benefits/?utm_campaign=morning_rounds&utm_medium=email&_hsenc=p2ANqtz--XahccMtgXVU3JMSaGAG82VCV4jsJT3Bn5YhOww-op5ZhK8mcopboNLfO6x2MBhkPcbcDNIjaCzrrzmngML6dickt04g&_hsmi=343359550&utm_content=343359550&utm_source=hs_email