Stem cell-derived dopaminergic cell transplantation shows encouraging results for Parkinson's disease

https://www.news-medical.net/news/20260709/Stem-cell-derived-dopaminergic-cell-transplantation-shows-encouraging-results-for-Parkinsons-disease.aspx The International Society for Stem Cell Research (ISSCR) today announced the presentation of new clinical data from the STEM-PD Phase I/II clinical trial at the ISSCR 2026 Annual Meeting. The study reports 12-month outcomes evaluating a cryopreserved, off-the-shelf dopaminergic progenitor cell product derived from human pluripotent stem cells for the treatment of Parkinson's disease.

Scientists trace severe irritability to the brain’s response to frustration

https://www.news-medical.net/news/20260710/Scientists-trace-severe-irritability-to-the-braine28099s-response-to-frustration.aspx From heightened activity and aggression in animals to altered brain responses in humans, the review shows how frustration research could reveal why irritability becomes clinically impairing.

Accelerating drug discovery through AI, automation, and next-generation DMTA

In this interview, industry experts Jon Wingfield and Wenshu Xu from TTP discuss the technologies and strategies transforming modern drug discovery. Drawing on decades of experience across pharmaceuticals, automation, and innovation, they explore how artificial intelligence, advanced data analytics, and increasingly autonomous laboratory systems are reshaping the design-make-test-analyze (DMTA) cycle. https://www.news-medical.net/news/20260619/Accelerating-drug-discovery-through-AI-automation-and-next-generation-DMTA.aspx?utm_source=azonetwork_newsletter&utm_medium=email&utm_campaign=drug_discovery_newsletter_9_july_2026

Scientists capture atomic images to improve RNA interference drug design +++ +++ ++

Scientists capture atomic images to improve RNA interference drug design https://www.news-medical.net/news/20260629/Scientists-capture-atomic-images-to-improve-RNA-interference-drug-design.aspx?utm_source=azonetwork_newsletter&utm_medium=email&utm_campaign=drug_discovery_newsletter_9_july_2026 Scientists capture atomic images to improve RNA interference drug designRNA interference is a natural mechanism for living cells to control whether specific genes are being used or not. Study identifies promising drug target to prevent neurodegenerative conditions https://www.news-medical.net/news/20260706/Study-identifies-promising-drug-target-to-prevent-neurodegenerative-conditions.aspx?utm_source=azonetwork_newsletter&utm_medium=email&utm_campaign=drug_discovery_newsletter_9_july_2026 Study identifies promising drug target to prevent neurodegenerative conditionsParkinson's disease (PD) is the second most common form of neurodegenerative disease and afflicts more than ten million people worldwide. While current therapies address disease symptoms, they do not prevent the underlying neurodegeneration that drives the disease. Clinical trial evaluates generative AI support tool in primary care https://www.news-medical.net/news/20260626/Clinical-trial-evaluates-generative-AI-support-tool-in-primary-care.aspx?utm_source=azonetwork_newsletter&utm_medium=email&utm_campaign=drug_discovery_newsletter_9_july_2026 Clinical trial evaluates generative AI support tool in primary careA large real-world clinical trial has found that a generative AI-powered support tool used to support frontline clinicians was safe and improved the quality of clinical decision-making but did not significantly change short-term patient outcomes. Insilico Medicine partners with Takeda for AI-driven drug discovery https://www.news-medical.net/news/20260702/Insilico-Medicine-partners-with-Takeda-for-AI-driven-drug-discovery.aspx?utm_source=azonetwork_newsletter&utm_medium=email&utm_campaign=drug_discovery_newsletter_9_july_2026 Insilico Medicine partners with Takeda for AI-driven drug discoveryInsilico Medicine, a leader in clinical-stage generative AI for drug discovery, today announced a strategic collaboration agreement with Takeda to use its proprietary end-to-end platform, Pharma.AI, to advance drug candidates across the company's therapeutic areas. WHO launches PARTNERS clinical trial for Bundibugyo virus treatments https://www.news-medical.net/news/20260703/WHO-launches-PARTNERS-clinical-trial-for-Bundibugyo-virus-treatments.aspx?utm_source=azonetwork_newsletter&utm_medium=email&utm_campaign=drug_discovery_newsletter_9_july_2026 WHO launches PARTNERS clinical trial for Bundibugyo virus treatmentsIn a major international effort to evaluate potential treatments for Ebola disease due to Bundibugyo virus (BVD), the PARTNERS clinical trial has opened enrolment today for patients in the Democratic Republic of the Congo. Insilico Medicine highlights AI drug discovery progress at executive summit https://www.news-medical.net/news/20260703/Insilico-Medicine-highlights-AI-drug-discovery-progress-at-executive-summit.aspx?utm_source=azonetwork_newsletter&utm_medium=email&utm_campaign=drug_discovery_newsletter_9_july_2026 Insilico Medicine highlights AI drug discovery progress at executive summitDr. Alex Aliper, Co-founder and President of Insilico Medicine, will attend the AI for Good Global Summit 2026 in Geneva, Switzerland, on July 7. New EV-SELEX strategy accelerates drug discovery for wide range of GPCRs https://www.news-medical.net/news/20260707/New-EV-SELEX-strategy-accelerates-drug-discovery-for-wide-range-of-GPCRs.aspx?utm_source=azonetwork_newsletter&utm_medium=email&utm_campaign=drug_discovery_newsletter_9_july_2026 New EV-SELEX strategy accelerates drug discovery for wide range of GPCRsG protein-coupled receptors (GPCRs) are the most abundantly expressed proteins in the human body, which regulate diverse physiological processes ranging from pain perception to hormone signaling. Collaborative AI system helps accelerate clinical trial design https://www.news-medical.net/news/20260707/Collaborative-AI-system-helps-accelerate-clinical-trial-design.aspx?utm_source=azonetwork_newsletter&utm_medium=email&utm_campaign=drug_discovery_newsletter_9_july_2026 Collaborative AI system helps accelerate clinical trial designAn artificial intelligence system that operates like a collaborative team of medical experts could accelerate clinical trial design, one of the most difficult steps in drug development, according to a new study by Weill Cornell Medicine investigators.

Dogs could transform the future of autism drug development

https://www.news-medical.net/news/20260625/Dogs-could-transform-the-future-of-autism-drug-development.aspx?utm_source=azonetwork_newsletter&utm_medium=email&utm_campaign=drug_discovery_newsletter_9_july_2026 For thirty years the search for autism medicines has hit the same wall, and a new peer-reviewed Perspective in Genomic Psychiatry suggests that the way around it has been sleeping at our feet the entire time. The article is a synthesis rather than a fresh experiment. It gathers a decade of scattered findings and makes a quiet, provocative case. The laboratory Beagle, that gentle and biddable companion, may be the missing bridge between the petri dish and the clinic.

Older adults face greater risk of mental health hospitalizations during extreme heatwaves

https://www.news-medical.net/news/20260710/Older-adults-face-greater-risk-of-mental-health-hospitalizations-during-extreme-heatwaves.aspx As the US recovers from its 4 July heatwave, a new study in Nature Health warns of an impending uptick in people attending hospitals for mental health and behavioral disorders, according to the first multi-country study of heatwave-related mental health hospitalization, led by Monash University in Australia.

Exposure to port-derived particles facilitates the replication of COVID-19 and cold viruses

https://www.news-medical.net/news/20260710/Exposure-to-port-derived-particles-facilitates-the-replication-of-COVID-19-and-cold-viruses.aspx Air pollution from cruise ships could be damaging the health of people living in port cities by increasing inflammation and susceptibility to viruses such as the common cold and COVID-19.