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Evaluating the Clinical Validity of Gene-Disease Associations: An Evidence-Based Framework Developed by the Clinical Genome Resource.

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Evidence Synthesis with an image of sequencing and a double helix

Last Posted: Jun 22, 2017

Evaluating the Clinical Validity of Gene-Disease Associations: An Evidence-Based Framework Developed by the Clinical Genome Resource.
Strande Natasha T et al. American journal of human genetics 2017 Jun (6) 895-906
Clinical Implementation of Pharmacogenomics for Personalized Precision Medicine: Barriers and Solutions.
Klein Michelle Elizabeth et al. Journal of pharmaceutical sciences 2017 Jun
Do What I Couldn't...and Go Save Your Life
Amy B Shainman, June, 2017
Gut microbiome and serum metabolome alterations in obesity and after weight-loss intervention.
Liu Ruixin et al. Nature medicine 2017 Jun
Impact of a 31-gene Expression Profiling Test for Cutaneous Melanoma on Dermatologists' Clinical Management Decisions.
Farberg Aaron S et al. Journal of drugs in dermatology : JDD 2017 May 16(5) 428-431
Is the atopic march related to confounding by genetics and early life environment? A systematic review of sibship and twin data.
Khan Sabria J et al. Allergy 2017 Jun

Rapid and specific detection of Asian- and African-lineage Zika viruses.

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Zika microsite button

From CDC-Authored Genomics Publication Database

This database contains CDC-authored publications in public health genomics including infectious diseases, newborn screening, reproductive health, genetic testing, cancer, chronic diseases, birth defects and developmental disabilities, environmental and occupational health as well as laboratory, bioinformatics and statistical methods.

Rapid and specific detection of Asian- and African-lineage Zika viruses.
Chotiwan Nunya et al. Science translational medicine 2017 May (388)
Persistence of Zika Virus in Body Fluids - Preliminary Report.
Paz-Bailey Gabriela et al. The New England journal of medicine 2017 Feb
Relative analytical sensitivity of donor nucleic acid amplification technology screening and diagnostic real-time polymerase chain reaction assays for detection of Zika virus RNA.
Stone Mars et al. Transfusion 2017 Feb
Detection of Zika Virus in Desiccated Mosquitoes by Real-Time Reverse Transcription PCR and Plaque Assay.
Burkhalter Kristen L et al. Emerging infectious diseases 2017 Apr (4)
Zika Virus RNA Replication and Persistence in Brain and Placental Tissue.
Bhatnagar Julu et al. Emerging infectious diseases 2017 Mar (3)

An update on Zika vaccine developments

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Zika microsite button

Last Posted: Jun 22, 2017

An update on Zika vaccine developments.
Durbin Anna et al. Expert review of vaccines 2017 Jun
Full-genome amplification and sequencing of Zika viruses using a targeted amplification approach.
Leguia Mariana et al. Journal of virological methods 2017 Jun
Should you be tested for Zika?
Analysis of Synonymous Codon Usage in Zika Virus.
Hussain Snawar et al. Acta tropica 2017 Jun
Epidemiology: Molecular mapping of Zika spread
Worobey M. Nature, Jun 15, 2017.
CDC analysis of data from US territories finds serious birth defects in about 1 in 12 fetuses or infants of pregnant women with Zika infection in the first trimester
CDC, June 7, 2017

ASH Announces Upcoming Sickle Cell Disease Guidelines

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Infographic: 5 Facts You Should Know About SCD

From From Genomics & Health Impact Scan Database

This database includes published scientific literature on evidence-based translation of genomic discoveries into improved health care and disease prevention that have a potential impact on population health.

ASH Announces Upcoming Sickle Cell Disease Guidelines,
by Mathew Shanley, Rare DR, June 19, 2017
With a rapper's death, harsh spotlight falls on slow progress against sickle cell
S Begley, StatNews, June 21, 2017
Sickle Cell Disease.
Piel Frédéric B et al. The New England journal of medicine 2017 376(16) 1561-1573
Sickle cell disease and implementation science: A partnership to accelerate advances.
King Allison A et al. Pediatric blood & cancer 2017 May
Sickle Cell in the Emergency Department

Development of a new real-time PCR screening kit for HbS and common beta-thalassemia mutations observed in Turkey

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Infographic: 5 Facts You Should Know About SCD

From HuGE Literature Finder Database

This database contains published literature on genetic associations and other human genome epidemiology

Development of a new real-time PCR screening kit for HbS and common beta-thalassemia mutations observed in Turkey.
Turkish journal of medical sciences 2017 Jun 47 (3): 973-978.
Kan Karaer Derya, Ergün Mehmet Ali, Ruhi Hatice Ilg?n, Öztürk Jale, Kara Halil, Reiso?lu Çakmak Deniz, Aydo?mu? Talihanur, Perçin Emriye Fer
Genome-wide association study to identify variants associated with vaso-occlusive pain in sickle cell anemia.
Blood 2017 Jun .
Chaturvedi Shruti, Bhatnagar Pallav, Bean Christopher J, Steinberg Martin H, Milton Jacqueline N, Casella James F, Barron-Casella Emily, Arking Dan E, DeBaun Michael
Clinical and genetic predictors of renal dysfunctions in sickle cell anaemia in Cameroon.
British journal of haematology 2017 May .
Geard Amy, Pule Gift D, Chetcha Chemegni Bernard, Ngo Bitoungui Valentina J, Kengne Andre P, Chimusa Emile R, Wonkam Ambroi
Do Alpha Thalassemia, Fetal Hemoglobin, and the UGT1A1 Polymorphism have an Influence on Serum Bilirubin Levels and Cholelithiasis in Patients with Sickle Cell Disease?
Molecular diagnosis & therapy 2017 May .
de Azevedo Laura Alencastro, Bonazzoni Joyce, Wagner Sandrine Comparsi, Farias Mariela Granero, Bittar Christina M, Daudt Liane, de Castro Simone Marti
SAR1a promoter polymorphisms are not associated with fetal hemoglobin in patients with sickle cell disease from Cameroon.
BMC research notes 2017 May 10 (1): 183.
Pule Gift Dineo, Bitoungui Valentina Josiane Ngo, Chemegni Bernard Chetcha, Kengne Andre Pascal, Wonkam Ambroi

Genome-wide association study to identify variants associated with vaso-occlusive pain in sickle cell anemia.

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Do you use the emregency department for care of sickle cell disease? What to know before you go.

From CDC-Authored Genomics Publication Database

Genome-wide association study to identify variants associated with vaso-occlusive pain in sickle cell anemia.
Chaturvedi Shruti et al. Blood 2017 Jun
Emergency department utilization by Californians with sickle cell disease, 2005-2014.
Paulukonis Susan T et al. Pediatric blood & cancer 2017 Jun 64(6)
Mortality of New York children with sickle cell disease identified through newborn screening.
Wang Ying et al. Genet. Med. 2015 Jun 17(6) 452-9
Incidence of sickle cell trait--United States, 2010.
Ojodu Jelili et al. MMWR Morb. Mortal. Wkly. Rep. 2014 Dec 12. 63(49) 1155-8
Health policy for sickle cell disease in Africa: experience from Tanzania on interventions to reduce under-five mortality.
Makani Julie et al. Trop. Med. Int. Health 2015 Feb 20(2) 184-7

Sickle Cell in the Emergency Department

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Do you use the emregency department for care of sickle cell disease? What to know before you go.

From CDC Information Database

This database includes general CDC public health information on specific diseases and health related topics. When available, the database displays genomic information from various CDC web pages. Users are also encouraged to conduct searches of CDC website for additional information.