CIENCIASMEDICASNEWS

Weekly Rundown: Moderna agrees to record settlement over COVID vaccine patents +++++

Weekly Rundown: Moderna agrees to record settlement over COVID vaccine patents FDA pilot programs, aging discoveries, and diagnostic advances led the week’s headlines. https://www.drugdiscoverynews.com/weekly-rundown-moderna-agrees-to-record-settlement-over-covid-vaccine-patents-17056 How close are scientists to stopping ALS in its tracks? Neflamapimod shows promise in slowing ALS by targeting protein clumps and restoring nerve cell function. https://www.drugdiscoverynews.com/how-close-are-scientists-to-stopping-als-in-its-tracks-17057 AI model trained on 100,000+ species learns to read and design genetic code A new biological foundation model analyzes genomic patterns across the tree of life and may accelerate disease research and synthetic biology. https://www.drugdiscoverynews.com/ai-model-trained-on-100-000-species-learns-to-read-and-design-genetic-code-17054 Engineered macrophages show promise against brain metastases Wake Forest researchers have reprogrammed macrophages to target metastatic tumors in the brain, offering a potential new approach where conventional therapies struggle. https://www.drugdiscoverynews.com/engineered-macrophages-show-promise-against-brain-metastases-17048 Gut bacteria duo may be behind chronic constipation Researchers uncover how microbes targeting the colon’s mucus may explain treatment-resistant constipation in Parkinson’s disease and other patients. https://www.drugdiscoverynews.com/gut-bacteria-duo-may-be-behind-chronic-constipation-17047

Hormones & Bone Health +++

Hormones & Bone Health Patch vs Pill: Bone Outcomes in FHA Transdermal HRT Superior to Oral Meds for FHA-Related Bone Loss Nancy A. Melville https://www.medscape.com/viewarticle/transdermal-hrt-superior-oral-meds-fha-related-bone-loss-2026a10006nb?ecd=mkm_ret_260308_mscpmrk_endo_hormones_etid8161371&uac=148436CN&impID=8161371 March 04, 2026 Does HRT Lower Osteoporosis Risk? Early Hormone Replacement Therapy Linked to Lower Osteoporosis Risk in Postmenopausal Women Lara Salahi https://www.medscape.com/viewarticle/early-hormone-replacement-therapy-linked-lower-osteoporosis-2026a10006oo?ecd=mkm_ret_260308_mscpmrk_endo_hormones_etid8161371&uac=148436CN&impID=8161371 March 04, 2026 What HRT Doesn’t Fix in Menopause Menopause, Mood, and Brain Structure: HRT May Not Fully Offset Changes Lizette Borreli https://www.medscape.com/viewarticle/menopause-mood-and-brain-structure-hrt-may-not-fully-offset-2026a100038m?ecd=mkm_ret_260308_mscpmrk_endo_hormones_etid8161371&uac=148436CN&impID=8161371 February 02, 2026

Online First - March 5, 2026 News Canada invests in cancer prevention research Karl Gruber ++ + ...

Assessment of survival benefit from sentinel node biopsy for melanoma: a systematic review and meta-analysis Alexander H R Varey, MBChB PhDa,b,c ∙ Marie B Weitemeyer, MDd ∙ Caroline A Gjorup, MD PhDa,d ∙ Prof Serigne N Lo, PhDa,b ∙ Gabrielle J Williams, PhDa,b ∙ Prof John F Thompson, MBBS MD https://www.thelancet.com/journals/lanonc/article/PIIS1470-2045(26)00026-4/fulltext?dgcid=hubspot_email_conferencealerts_sso26&utm_campaign=conferencealerts&utm_medium=email&_hsenc=p2ANqtz-_pEvw1mSbW7soDAY4WG0j186Gmr1-af7nGXMZ7_JmSAokse84gZAVIP77XBiyBjVJ9NrJEWAQW36qg9MfI1QACC0aMsg&_hsmi=407292777&utm_content=407292777&utm_source=hs_email Sentinel lymph node procedure in the era of new melanoma therapies Simone Ribero simone.ribero@unito.it ∙ Pietro Quaglino https://www.thelancet.com/journals/lanonc/article/PIIS1470-2045(26)00063-X/abstract?utm_campaign=conferencealerts&utm_medium=email&dgcid=hubspot_email_conferencealerts_sso26&_hsenc=p2ANqtz-9BaF4zSmoWhjaLv91cr3ClKBMEfeIBGUkYq-9vkU-WDRd-qtAuY682h2QpFVGOeUOtmnRYe6b9tLMrysX0FcaWC3K5mQ&_hsmi=407292777&utm_content=407292777&utm_source=hs_email Online First https://www.thelancet.com/journals/lanonc/onlinefirst

Reproductive, Bone, & Women’s Health Access ++++

Reproductive, Bone, & Women’s Health Access Home Screening Appeals to Women Facing Healthcare Barriers Home Screening Appeals to Women Facing Healthcare Barriers Edited by Katie Lennon https://www.medscape.com/viewarticle/home-screening-appeals-women-facing-healthcare-barriers-2026a100058f?ecd=mkm_ret_260308_mscpmrk-OUS_InFocus_etid8160253&uac=148436CN&impID=8160253 February 19, 2026 Energy Deficit and Bone Loss in Female Athletes Energy Deficit and Bone Loss in Female Athletes Maria Cristina Valsecchi https://www.medscape.com/viewarticle/energy-deficit-and-bone-loss-female-athletes-2026a100057n?ecd=mkm_ret_260308_mscpmrk-OUS_InFocus_etid8160253&uac=148436CN&impID=8160253 Medscape Europe February 19, 2026 Hormonal Drivers of Premenstrual Mood Disorders Hormonal Drivers of Premenstrual Mood Disorders Martine Perez https://www.medscape.com/viewarticle/hormonal-drivers-premenstrual-mood-disorders-2026a10004x1?ecd=mkm_ret_260308_mscpmrk-OUS_InFocus_etid8160253&uac=148436CN&impID=8160253 Medscape Europe February 17, 2026 HIV & Menopause: What We’re Learning HIV and Menopause: A Combo We’re Just Beginning to Understand Lisa O’Mary https://www.medscape.com/viewarticle/hiv-and-menopause-combo-were-just-beginning-understand-2026a10004tn?ecd=mkm_ret_260308_mscpmrk-OUS_InFocus_etid8160253&uac=148436CN&impID=8160253 February 16, 2026

GLP-1 drugs linked to higher fracture risk, osteoporosis and gout, new studies suggest By Deirdre Bardolf Fox News Published March 7, 2026 5:51pm EST

GLP-1 drugs linked to higher fracture risk, osteoporosis and gout, new studies suggest Researchers say bone health should be assessed before starting medications like Ozempic in adults over 65 By Deirdre Bardolf Fox News Published March 7, 2026 5:51pm EST https://www.foxnews.com/health/glp-1-drugs-tied-fracture-risk-older-adults-new-studies-suggest

Ancient herb known as ‘nature’s Valium’ touted for improving sleep and anxiety By Angelica Stabile Fox News Published March 8, 2026 9:00am EDT

Ancient herb known as ‘nature’s Valium’ touted for improving sleep and anxiety Valerian shows some benefits in trials, but doctors disagree on comparisons to prescription drug Angelica Stabile By Angelica Stabile Fox News Published March 8, 2026 9:00am EDT https://www.foxnews.com/health/ancient-herb-known-natures-valium-touted-improving-sleep-anxiety