CIENCIASMEDICASNEWS

viernes, 7 de agosto de 2026

Could Functional Precision Medicine Be the New Precision Oncology? August 6, 2026, by Anthony Letai, M.D., Ph.D. +++

Could Functional Precision Medicine Be the New Precision Oncology? August 6, 2026, by Anthony Letai, M.D., Ph.D. https://www.cancer.gov/news-events/cancer-currents-blog/2026/director-letai-functional-precision-medicine-workshop?cid=eb_govdel NCI’s Cancer Currents Blog is live again, bringing you timely news and insights from across cancer research. The blog will continue to highlight advances in cancer science, the work being done in clinical trials, FDA approvals, NCI priorities and guidance, and more. You’ll also learn about emerging research, important developments, and what they may mean for patients, caregivers, researchers, and the broader community. How Decades of NCI Support Led to Groundbreaking Discoveries: The Story of Immune Checkpoint Inhibitors July 21, 2026, by Linda Wang https://www.cancer.gov/news-events/cancer-currents-blog/2026/nci-role-checkpoint-inhibitors?cid=eb_govdel Reflections on Progress and Partnership at ASCO 2026 June 16, 2026, by Anthony Letai, M.D., Ph.D. https://www.cancer.gov/news-events/cancer-currents-blog/2026/director-letai-asco-reflections-progress?cid=eb_govdel

Academia Mental Health and Well-Being +... +

https://www.academia.edu/journals/academia-mental-health-and-well-being/articles?source=journal-top-nav An attempt at conceptualizing a multidimensional body-brain nature of stress reduction Maria Kosma [1] https://www.academia.edu/2997-9196/3/2/10.20935/MHealthWellB8261 About 23% of US adults live with a mental illness. Young adults (36.2%) and women (26.4%) report the highest rates of mental health disorders. The typical brain/cognitive-oriented first-line treatments of anxiety disorders are pharmacotherapy, psychological interventions, and transcranial stimulation. Such approaches have several limitations, including medical costs, adverse effects, treatment resistance, limited evidence of long-term effects, and high relapse rates. Instead of relying solely on ultra-cognitive therapies, it is worth examining the embodied nature of stress reduction (body–mind unison). Therefore, the purpose of this conceptual mini review was to analyze how exercise programs, such as endurance training and holistic body–mind movement, modulate the hypothalamic–pituitary–adrenal (HPA) axis. Grounded in Merleau-Ponty’s philosophical underpinnings of embodiment, it was hypothesized that a shapely body schema (habitual body) via exercise can facilitate the strengthening of the HPA axis. A critical narrative review of healthy adults was conducted to test and support this hypothesis. Merleau-Ponty challenged Cartesian mind–body dualism and showcased how consciousness is embodied: it derives from the union of body and mind. Exercise facilitates this union by leading to a balanced body schema formed as a Gestalt. Mental health is not the outcome of a unidirectional stimulus-response model from the brain to the body, but holistic and embodied via a strong body schema. Regular and appropriate exercise training can strengthen the body schema and thus the function of the HPA axis by connecting its in-itself elements (e.g., cortisol secretion) and for-itself essence (e.g., perceptions, emotions, and breathing regulation) for health and well-being.

News & Perspectives: The Promise and Perils of Alternative Cancer Clinics ++++++

News & Perspectives: The Promise and Perils of Alternative Cancer Clinics https://www.medscape.com/viewarticle/promise-and-perils-alternative-cancer-clinics-2026a1000qp7?ecd=wnl_edit_tpal_etid8574839&uac=148436CN&impID=8574839 Scientists May Have a New Explanation for Excessive Sweating https://www.medscape.com/viewarticle/scientists-may-have-new-explanation-excessive-sweating-2026a1000qr1?ecd=wnl_edit_tpal_etid8574839&uac=148436CN&impID=8574839 Is Breast Really Best? https://www.medscape.com/viewarticle/breast-really-best-2026a1000q12?ecd=wnl_edit_tpal_etid8574839&uac=148436CN&impID=8574839 Friendly Physician Arrangements: How to Protect Yourself https://www.medscape.com/viewarticle/friendly-physician-arrangements-how-protect-yourself-2026a1000qd9?ecd=wnl_edit_tpal_etid8574839&uac=148436CN&impID=8574839 Pandora’s Message Portals https://www.medscape.com/viewarticle/pandoras-message-portals-2026a1000puh?ecd=wnl_edit_tpal_etid8574839&uac=148436CN&impID=8574839 Next Step for Australian UCCs: Ensuring Quality and Safety https://www.medscape.com/viewarticle/next-step-australian-uccs-ensuring-quality-and-safety-2026a1000p3c?ecd=wnl_edit_tpal_etid8574839&uac=148436CN&impID=8574839

Clinical Perspectives on the Use of PI3K/AKT Pathway Inhibitors in the Management of HR+/HER2− Metastatic Breast Cancer Authors: Peter Schmid, MD, PhD, FRCP; Kevin Kalinsky, MD, MS, FASCO; Frédérique Penault-Llorca, MD, PhD

https://www.medscape.org/viewarticle/clinical-perspectives-use-pi3k-akt-pathway-inhibitors-2026a100087h?page=1&src=mkmcmr_driv_stan_mscpedu_260806-OUS-HONC-clinical-perspectives-use-pi3k-akt-pathway-inhibitors-2026a100087h-cta&uac=148436CN

FDA grants accelerated approval to vusolimogene oderparepvec-wtpg in combination with nivolumab for melanoma

https://www.fda.gov/drugs/resources-information-approved-drugs/fda-grants-accelerated-approval-vusolimogene-oderparepvec-wtpg-combination-nivolumab-melanoma On August 6, 2026, the Food and Drug Administration granted accelerated approval to vusolimogene oderparepvec-wtpg (Tudriqev, Replimune, Inc.), a genetically modified oncolytic viral therapy, in combination with nivolumab for the treatment of adult patients with unresectable advanced cutaneous melanoma who experienced disease progression on a programmed death receptor-1 (PD-1)-blocking antibody-based regimen.