jueves, 11 de junio de 2026

TB vaccine from the 1920s shows promise in diabetes trial The shot reduced insulin use for people with type 1 diabetes and another autoimmune condition. By Viviane Callier

https://www.nature.com/articles/d41586-026-01825-w?utm_source=Live+Audience&utm_campaign=be71cea477-nature-briefing-daily-20260610&utm_medium=email&utm_term=0_-33f35e09ea-50432164 A century-old vaccine against tuberculosis helps to regulate blood sugar in people with certain types of diabetes, such that they can reduce their insulin use, according to the results of a phase II clinical trial. The finding adds support for the once-controversial hypothesis that vaccines made with living but weakened pathogens can protect against both their target disease and off-target ones.

Rome V: refining the language of gut–brain disorders The Lancet Gastroenterology & Hepatology ++... ++

Rome V: refining the language of gut–brain disorders The Lancet Gastroenterology & Hepatology https://www.thelancet.com/journals/langas/article/PIIS2468-1253(26)00157-3/fulltext?dgcid=raven_jbs_etoc_email Jul 2026 Volume 11Number 7p541-644, e9 https://www.thelancet.com/journals/langas/issue/vol11no7/PIIS2468-1253(26)X2005-2 The small interfering RNA imdusiran as single and multiple doses in healthy, randomised individuals and non-randomised individuals with chronic hepatitis B (AB-729–001): a phase 1a/b trial Prof Man-Fung Yuen, MD, DSca Send email to mfyuen@hku.hk ∙ Prof Edward Gane, MDb,c ∙ Jacinta A Holmes, PhDd ∙ Prof Simone I Strasser, MDe ∙ Apinya Leerapun, MDf ∙ Wattana Sukeepaisarnjaroen, MDg ∙ et al. https://www.thelancet.com/journals/langas/article/PIIS2468-1253(26)00058-0/abstract?dgcid=raven_jbs_etoc_feature_langas Adjuvant chemoradiotherapy versus completion total mesorectal excision after local excision for early rectal cancer (TESAR): a multicentre, randomised, controlled, phase 3, non-inferiority trial Laura R Moolenaar, MDa,b ∙ Mahsoem Ali, BSca,b ∙ Theo J Aufenacker, MD PhDc ∙ Prof Geerard L Beets, MD PhDd,e ∙ Robbert J I Bosker, MD PhDf ∙ Tineke E Buffart, MD PhDb,g ∙ et al. https://www.thelancet.com/journals/langas/article/PIIS2468-1253(26)00109-3/abstract?dgcid=raven_jbs_etoc_feature_langas

Morning Briefing: FDA’s Greenlight of Old Chemical Offers Chance To Restore Faith in Sunscreen +...

https://kffhealthnews.org/morning-briefing/thursday-june-11-2026/

NIH research establishes new framework for the role of senescence in aging First large-scale atlas of senescent cells could help inform future therapies for age-related diseases.

NIH research establishes new framework for the role of senescence in aging First large-scale atlas of senescent cells could help inform future therapies for age-related diseases. A research consortium funded by the National Institutes of Health (NIH)has established a new framework to identify and catalog senescent cells – cells that stop dividing but remain active in the body. Because senescent cells accumulate with age and are thought to contribute to many age-related conditions, researchers are working to better understand the roles they play in health and disease. In a compendium of papers published in the June 11 issue of Cell, the consortium presents the first comprehensive atlas of senescent cells across the human body, a foundational step toward developing new therapies for age-related diseases. https://www.nih.gov/news-events/news-releases/nih-research-establishes-new-framework-role-senescence-aging

No escape: crisis of extreme heat indoors The Lancet Regional Health – South East Asia ++... ++

No escape: crisis of extreme heat indoors The Lancet Regional Health – South East Asia https://www.thelancet.com/journals/lansea/article/PIIS2772-3682(26)00084-3/fulltext?dgcid=raven_jbs_etoc_email Jun 2026 Volume 49 https://www.thelancet.com/journals/lansea/issue/vol49nonull/PIIS2772-3682(26)X2004-2 A decision-support tool for management of advanced epithelial ovarian cancer in a single centre in India (CT PAUSE Nomogram): a prospective Study (2022–2024) Angelin Grace Jeslina ∙ Shobiga Natarajana ∙ Sneha Hiriyannaa ∙ Renu Ninana ∙ Goldwin Helan Cecila ∙ Betty Simona ∙ et al. https://www.thelancet.com/journals/lansea/article/PIIS2772-3682(26)00053-3/fulltext?dgcid=raven_jbs_etoc_feature_lansea Self-management education and support for type 2 diabetes in Thailand: a cluster randomized trial (2019–2021) Piyachon Aramrata,k Send email to piyachon.62@gmail.com ∙ Iliatha Papachristou Nadalb,c,k Send email to iliatha.papachristounadal@kcl.ac.uk ∙ Poppy Alice Carson Mallinsonb Send email to Poppy.Mallinson1@lshtm.ac.uk ∙ Kanokporn Pinyopornpanisha Send email to knp_02@hotmail.com ∙ Orawan Quansrid Send email to orawan.qua@mahidol.ac.th ∙ Kittipan Rerkaseme,f Send email to rerkase@gmail.com ∙ et al. https://www.thelancet.com/journals/lansea/article/PIIS2772-3682(26)00063-6/fulltext?dgcid=raven_jbs_etoc_feature_lansea

Navigating Myelofibrosis-Associated Anemia Together: Empowering Collaboration and Communication Authors: Francesco Passamonti, MD

https://www.medscape.org/viewarticle/navigating-myelofibrosis-associated-anemia-together-2026a10007ks?page=1&src=mkmcmr_driv_stan_mscpedu_260611-OUS-HONC-navigating-myelofibrosis-associated-anemia-together-2026a10007ks-cta&uac=148436CN

Editorial Persistent gaps in skin cancer prevention eClinicalMedicine +++ +...

A multiparameter model (OsteoSC-M3) for early detection and risk stratification of osteoporosis in women: a multicentre cohort study in China Xiaoyan Tenga,d ∙ Ji Qiaob,d ∙ Yang Xuea ∙ Li Weib ∙ Xiaozhong Jic Send email to 1263830302@qq.com ∙ Yuzhen Du https://www.thelancet.com/journals/eclinm/article/PIIS2589-5370(26)00150-1/fulltext?dgcid=hubspot_update_feature_updatealerts_eclinm&utm_campaign=update-eclinm&utm_medium=email&_hsenc=p2ANqtz-_bEYezQM9Xvod0lOkq-F357XdibtZepGC48wNJH3SKccGxNZcCyGHNOwYxTjgbwd_ZsO9ek9L26yMkJRrri8uxw183kw&_hsmi=423208303&utm_content=423132158&utm_source=hs_email Oropouche virus: transmission, epidemiology, genetic diversity, and public health implications Lorenzo Subissia Send email to subissil@who.int ∙ James R. Otienoa ∙ Christopher Ruisb,c,d ∙ Ingrid Rabea ∙ Anurag Agrawale ∙ Laith Jamal Abu-Raddadf ∙ et al. https://www.thelancet.com/journals/eclinm/article/PIIS2589-5370(26)00118-5/fulltext?dgcid=hubspot_update_feature_updatealerts_eclinm&utm_campaign=update-eclinm&utm_medium=email&_hsenc=p2ANqtz-9XR7A6gPKd1WCI9m0Qe3VCJIMezhcGuzrxXrfOAHvW_lIFa8CmL6zzst27vJf7z_BVp2X_6bZO8bnpT6J43u_9QeZMRQ&_hsmi=423208303&utm_content=423132158&utm_source=hs_email The next phase in Long COVID research: addressing the ethical challenges in trials of disease-modifying treatments Saskia Hendriksa Send email to saskia.hendriks@nih.gov ∙ Christine Gradya ∙ Megan L. Fitzgeraldb,c ∙ Rachel S. Grossd ∙ Christine Maughane ∙ Michael J. Pelusof ∙ et al. https://www.thelancet.com/journals/eclinm/article/PIIS2589-5370(26)00166-5/fulltext?dgcid=hubspot_update_feature_updatealerts_eclinm&utm_campaign=update-eclinm&utm_medium=email&_hsenc=p2ANqtz-8I85G-eL9Hxaykm7ysyrb8PJXKgh-sPtjs6Yt-cshWZO53n9Ksm0WTT7MZuyk1gt62Bh4OSvfdygwSw2QcCWh0BN1lDg&_hsmi=423208303&utm_content=423132158&utm_source=hs_email Editorial Persistent gaps in skin cancer prevention eClinicalMedicine https://www.thelancet.com/journals/eclinm/issue/vol95nonull/PIIS2589-5370(26)X2004-1