domingo, 22 de marzo de 2026

Understanding the microbiome may hold the key to personalized therapies Advances in high-throughput experimentation and machine learning are helping researchers map how gut microbes influence drug response and health outcomes.

https://www.drugdiscoverynews.com/understanding-the-microbiome-may-hold-the-key-to-personalized-therapies-17075

Weekly Rundown: Study highlights overlooked role of fathers’ health in pregnancy outcomes FDA approvals, mass spectrometry advancements, personalized gene therapies, and more led the news this week.

https://www.drugdiscoverynews.com/weekly-rundown-study-highlights-overlooked-role-of-fathers-health-in-pregnancy-outcomes-17078

Comment e120 Thank you to our 2025 peer reviewers with an update on our inclusion and diversity commitments The Lancet Haematology Editors +++ +...

Varnimcabtagene autoleucel for adults with relapsed or refractory B-cell precursor acute lymphoblastic leukaemia in Spain (CART19-BE-02): a multicentre, single-arm, phase 2 trial Valentín Ortiz-Maldonado, MDa,e,f ∙ Núria Martínez-Cibrian, MDa,e,f ∙ Leticia Alserawan, BPharmb,e ∙ Marta Español-Rego, BPharmb,e ∙ Sergio Navarro-Velázquez, BScb,e ∙ Nil Albiol, MDa,e,f ∙ et al. https://www.thelancet.com/journals/lanhae/article/PIIS2352-3026(25)00328-X/abstract?utm_campaign=update-lanhae&utm_medium=email&dgcid=hubspot_update_feature_updatealerts_lanhae&_hsenc=p2ANqtz-9ERAc1k4ZivAtyYe7PQ-Ft9Aj10fyfWgQLMGzFdZ5f0_qm61i1yRq-zvcEOcw0F4ouNZrlBXYk9PY7a6aBN_P5DQiWJQ&_hsmi=408878165&utm_content=408392511&utm_source=hs_email Patient-reported outcomes in newly diagnosed patients with FLT3-internal-tandem-duplication-positive acute myeloid leukaemia receiving standard chemotherapy plus quizartinib or placebo (QuANTUM-First): a global, randomised, placebo-controlled, phase 3 trial Esther N Olíva, MDa enoliva@gmail.com ∙ Francesco Cottone, PhDb ∙ Sudhir Unni, PhDc ∙ Anne Correges, MSd ∙ Jes B Hansen, MSe ∙ Xiaocong Li Marston, PhDf ∙ et al. https://www.thelancet.com/journals/lanhae/article/PIIS2352-3026(25)00361-8/abstract?utm_campaign=update-lanhae&utm_medium=email&dgcid=hubspot_update_feature_updatealerts_lanhae&_hsenc=p2ANqtz--9lCrjEwUlFyJdJ2NNPFxVufe1XDr_Q-kAJIBHurJ8u8Q7i4rABw2EweYL4Yy-Wx1GDK2GaeqFnK2s3WQ6NUI2Jte7CQ&_hsmi=408878165&utm_content=408392511&utm_source=hs_email Global equity in paediatric cancer care The Lancet Haematology https://www.thelancet.com/journals/lanhae/article/PIIS2352-3026(26)00042-6/fulltext?dgcid=hubspot_update_feature_updatealerts_lanhae&utm_campaign=update-lanhae&utm_medium=email&_hsenc=p2ANqtz--H8oTyxujatb_YqEx2bVOj_Fa_hoJ8wq7PKRpknaqlsOCA4jdJkFsxeqY0T4tXYYoqCUbqkMmrspU9ACjlYYjmLH_FGQ&_hsmi=408878165&utm_content=408392511&utm_source=hs_email Mar 2026 Volume 13Number 3e119-e186 https://www.thelancet.com/journals/lanhae/issue/vol13no3/PIIS2352-3026(26)X

Oral health in the Americas: progress, gaps, and the path to universal coverage The Lancet Regional Health – Americas ++... ++

Oral health in the Americas: progress, gaps, and the path to universal coverage The Lancet Regional Health – Americas https://www.thelancet.com/journals/lanam/article/PIIS2667-193X(26)00088-8/fulltext?dgcid=raven_jbs_etoc_email Mar 2026 Volume 55 https://www.thelancet.com/journals/lanam/issue/vol55nonull/PIIS2667-193X(25)X0014-4 The prevalence of cannabis use pre-versus post-cannabis legalization in Canada by mental health status: findings from national repeat cross-sectional surveys Samantha Rundlea ∙ Maryam Iraniparastb ∙ David Hammond https://www.thelancet.com/journals/lanam/article/PIIS2667-193X(26)00002-5/fulltext?dgcid=raven_jbs_etoc_feature_lanam Associations between state-level abortion restrictions and postpartum depression symptoms from a United States nationwide cohort Maetal E. Haas-Kogana ∙ Andrea Pelletierb,c ∙ Amanda Koirec,d,e ∙ Primavera A. Spagnoloc,d,e ∙ Deborah Bartz https://www.thelancet.com/journals/lanam/article/PIIS2667-193X(26)00040-2/fulltext?dgcid=raven_jbs_etoc_feature_lanam

Tuberculosis at a crossroads The Lancet Global Health + ++ +...

Tuberculosis at a crossroads The Lancet Global Health https://www.thelancet.com/journals/langlo/article/PIIS2214-109X(26)00071-9/fulltext?dgcid=raven_jbs_etoc_email Effects of climate change on physical inactivity: a panel data study across 156 countries from 2000 to 2022 Christian García-Witulski, PhDa,b,c christian_garcia@uca.edu.ar ∙ Mariano Rabassa, PhDa ∙ Oscar Melo, PhDd ∙ Juliana Helo Sarmiento, PhD https://www.thelancet.com/journals/langlo/article/PIIS2214-109X(25)00472-3/fulltext?dgcid=raven_jbs_etoc_feature_langlo Energy and health in low-income and middle-income countries https://www.thelancet.com/series-do/energy-health-2026?dgcid=raven_jbs_etoc_feature_langloenergyhealth26 Apr 2026 Volume 14Number 4e475-e667 https://www.thelancet.com/journals/langlo/issue/vol14no4/PIIS2214-109X(26)X2002-2

Barriers to accessing cataract surgery The Lancet Healthy Longevity ++... ++

Barriers to accessing cataract surgery The Lancet Healthy Longevity https://www.thelancet.com/journals/lanhl/article/PIIS2666-7568(26)00022-X/fulltext?dgcid=raven_jbs_etoc_email Feb 2026 Volume 7Number 2 https://www.thelancet.com/journals/lanhl/issue/vol7no2/PIIS2666-7568(26)X2002-5 The impact of exercise interventions on domains of quality of life in women diagnosed with breast cancers during chemotherapy treatment: a meta-analytic review LaShae D Rolle, MPHa,b,c lashaerolle@miami.edu ∙ Soyeon Ahn, PhDd ∙ Elle M Mezzio, BSb,c ∙ Madalyn Wheeler, MSEdb,c,d ∙ Loren Yavelberg, PhDb,c ∙ Carmen J Calfa, MDb,c ∙ et al. https://www.thelancet.com/journals/lanhl/article/PIIS2666-7568(26)00003-6/fulltext?dgcid=raven_jbs_etoc_feature_lanhl The effects of daily low-dose aspirin on white matter hyperintensity lesions and retinal vascular calibre in healthy older adults: the ENVIS-ion exploratory neuroimaging substudy of the ASPREE randomised clinical trial Walter P Abhayaratna, MBBS PhDa,b walter.p.abhayaratna@act.gov.au ∙ Prof Christopher M Reid, PhDb,d ∙ Katherine L Webb, MAb ∙ Prof Rory Wolfe, PhDb ∙ Ruth E Trevaks, PhDb ∙ Liubov Robman, MBBS PhDb,e ∙ et al. https://www.thelancet.com/journals/lanhl/article/PIIS2666-7568(25)00134-5/fulltext?dgcid=raven_jbs_etoc_feature_lanhl

Editorial p187 Innovation is needed to avoid closure of rural US hospitals The Lancet Respiratory Medicine +++ +...

Bisoprolol to prevent adverse cardiac events (PACE) in COPD: a multicentre, double-blind, randomised, controlled, phase 3 trial Prof Christine R Jenkins, MDa ∙ Allison Martin, PhDa ∙ Catherina L Chang, MDb ∙ Prof Richard Beasley, DScc ∙ Jeremy P Wrobel, PhDd ∙ Prof Vanessa M McDonald, PhDe ∙ et al. https://www.thelancet.com/journals/lanres/article/PIIS2213-2600(25)00390-X/abstract?utm_campaign=update-lanres&utm_medium=email&dgcid=hubspot_update_feature_updatealerts_lanres&_hsenc=p2ANqtz-8Yj1ZmJgVvNADnhFd5zGVdXuEIAThMdcjymAynhfwb2u0r79S5_Bc4I93BEn1GBxTXmzlnNw55xz4aGPuPCvza82Pjfg&_hsmi=409018631&utm_content=408447723&utm_source=hs_email Burden of chronic respiratory disease in Asia, 1990–2023: a systematic analysis for the Global Burden of Disease Study 2023 GBD 2023 Asia Chronic Respiratory Disease Collaborators https://www.thelancet.com/journals/lanres/article/PIIS2213-2600(25)00404-7/abstract?utm_campaign=update-lanres&utm_medium=email&dgcid=hubspot_update_feature_updatealerts_lanres&_hsenc=p2ANqtz-8oQ-uXA50bYIbZcFozgfMDAcO7VxLenh8HuIvlEiIHub_NsBpTpq9-3sQLt24AlcsrUsT1q6tR4YRlrlHJ0pZFAQncew&_hsmi=409018631&utm_content=408447723&utm_source=hs_email Survival effect of prehospital emergency anaesthesia with intubation in risk-stratified patients with major trauma: a causal modelling study Amy PK Nelson, MBChBa,b amy.nelson@ucl.ac.uk ∙ Nick Dodds, MBChBc ∙ Mohamad Zeina, MBBSa ∙ Alfred Balston, MBBSd ∙ Dominic Giles, PhDa ∙ William H Seligman, BMBChe ∙ et al. https://www.thelancet.com/journals/lanres/article/PIIS2213-2600(25)00370-4/fulltext?dgcid=hubspot_update_feature_updatealerts_lanres&utm_campaign=update-lanres&utm_medium=email&_hsenc=p2ANqtz-9MaG_ZPiUNb5MofxoVflwDJ5el45vB5xu5o6zK6hO9r0SwBKtSrKld8cjc8FvWSYw5fYT9z8hMbtWdBGNszCUyz1rDAQ&_hsmi=409018631&utm_content=408447723&utm_source=hs_email Editorial p187 Innovation is needed to avoid closure of rural US hospitals The Lancet Respiratory Medicine https://www.thelancet.com/journals/lanres/issue/vol14no3/PIIS2213-2600(26)X2002-1