sábado, 18 de abril de 2026
New study highlights fructose’s unique role in metabolic disease
https://www.news-medical.net/news/20260417/New-study-highlights-fructosee28099s-unique-role-in-metabolic-disease.aspx
A new report, published today in Nature Metabolism, is shedding light on the distinct and underappreciated role of fructose in driving disease, separate from its role as a simple source of calories.
Key gene variants tied to developmental dysplasia of the hip and osteoarthritis
https://www.news-medical.net/news/20260417/Key-gene-variants-tied-to-developmental-dysplasia-of-the-hip-and-osteoarthritis.aspx
Developmental dysplasia of the hip (DDH) is a polygenetic disorder that increases the risk of hip osteoarthritis. A new multiethnic study finds that variations in three genes related to collagen and bone formation are linked to DDH. Other downstream genes are also linked to hip osteoarthritis. These findings point to possible mechanisms behind DDH and potential targets for new therapies against hip osteoarthritis.
Transdermal therapy restores anti-tumor immunity in bladder cancer models Preclinical data show a first-in-class transdermal bicarbonate therapy increases tumor pH, reactivates T cells and slows bladder tumor growth in mice.
https://www.drugdiscoverynews.com/transdermal-therapy-restores-anti-tumor-immunity-in-bladder-cancer-models-17130
Extracellular acidity is a common feature of many solid tumors, similar to hypoxia. Increased metabolic rates, higher glycolysis and inadequate vasculature all contribute to the accumulation of acid in the tumor microenvironment (TME). This aspect is also one of their most effective defenses.
Weekly Rundown: Research finds no increased autism risk from Tylenol during pregnancy New hair loss treatments, company acquisitions, artificial neurons, and more led the news this week.
https://www.drugdiscoverynews.com/weekly-rundown-research-finds-no-increased-autism-risk-from-tylenol-during-pregnancy-17129
Research finds no increased autism risk from acetaminophen during pregnancy
Taking acetaminophen (Tylenol) during pregnancy does not increase the risk of autism spectrum disorder in children, according to a large population-based study from Denmark published in JAMA Pediatrics. Researchers analyzed more than 1.5 million births between 1997 and 2022 using national health registry data, including over 31,000 children exposed to acetaminophen in utero, and found autism rates of 1.8 percent among exposed children compared with three percent among those not exposed. This evidence aligns with a previous study in Sweden, published in 2024, which showed that initial signals of a small association between prenatal acetaminophen use and neurodevelopmental conditions disappeared once researchers accounted for shared familial factors using sibling-controlled analyses.
“I never let breast cancer disable me.” April 15, 2026
https://news.va.gov/146174/i-never-let-breast-cancer-disable-me/
Navy Veteran diagnosed at 31 speaks candidly
Heather Elliott was 31 years old when she was diagnosed with breast cancer, nearly three decades younger than the average age of diagnosis in the United States. Genetic testing showed no hereditary link, and with no family history to explain it, Elliott sought answers elsewhere. Years later, the possibility that toxic exposures during her deployment to the Gulf region may have played a role was considered. Finally, under the PACT Act, her breast cancer became recognized as service connected.
Knowledge is power: Free online mental health courses
https://news.va.gov/146130/knowledge-power-free-mental-health-courses/
Self-paced mental health tools Veterans can use anytime
Are you a Veteran facing common challenges like managing anger, insomnia or substance use? Discover VeteranTraining.va.gov, VA’s award-winning online mental health resource designed just for you.
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