Human adenovirus detection in rural community water sources in central-west Brazil Graziela Picciola Bordoni1,*ORCID iD , Lucas Candido Gonçalves Barbosa2ORCID iD , Fernando Santos Lima1ORCID iD , Thais Reis Oliveira2ORCID iD , José Daniel Gonçalves Vieira1ORCID iD , Paulo Sergio Scalize3ORCID iD , Lilian Carla Carneiro1,2

https://www.academia.edu/3143-0481/2/3/10.20935/AcadImmunoDis8447 Introduction: Poor and limited access to improved water, sanitation and hygiene (WASH) services, common in rural communities in developing countries, may lead to a high burden of enteric infections and the spread of fecal organisms. In the absence of a public water distribution network, rural areas obtain their water supply from surface and/or groundwater sources, where microbial quality is often unknown. Because adenoviruses are highly persistent in water and widely distributed in the environment, they have become an important group of enteric viruses and may potentially be involved in waterborne outbreaks. https://www.academia.edu/3143-0481/2/3/10.20935/AcadImmunoDis8447?email_action=download

Challenging the Confines of Risk of Recurrence in High-Risk HR+/HER2- Early Breast Cancer Authors: Joyce A. O’Shaughnessy, MD; Priya Rastogi, MD; Seth Wander, MD, PhD

https://www.medscape.org/viewarticle/challenging-confines-risk-recurrence-high-risk-hr-her2-early-2026a1000bq3?page=1&src=mkmcmr_driv_stan_mscpedu_261023-OUS-HONC-challenging-confines-risk-recurrence-high-risk-hr-her2-early-2026a1000bq3-cta&uac=148436CN

Year-long trial finds NAD-boosting supplement fails to improve early Parkinson's symptoms (+++ +++ +++ +++)

Year-long trial finds NAD-boosting supplement fails to improve early Parkinson's symptoms https://www.news-medical.net/news/20261012/Year-long-trial-finds-NAD-boosting-supplement-fails-to-improve-early-Parkinsons-symptoms.aspx?utm_source=news_medical_newsletter&utm_medium=email&utm_campaign=neurology_and_neuroscience_newsletter_21_october_2026 Year-long trial finds NAD-boosting supplement fails to improve early Parkinson's symptomsIn a phase 3 randomized clinical trial involving 410 people with early Parkinson disease, 52 weeks of nicotinamide riboside supplementation increased blood NAD levels but failed to improve clinical outcomes compared with placebo. Participants receiving the supplement had modestly worse overall disease scores, although the difference was below the threshold generally considered clinically meaningful. People who walk more each day tend to score better on several brain tests https://www.news-medical.net/news/20261014/People-who-walk-more-each-day-tend-to-score-better-on-several-brain-tests.aspx?utm_source=news_medical_newsletter&utm_medium=email&utm_campaign=neurology_and_neuroscience_newsletter_21_october_2026 People who walk more each day tend to score better on several brain testsResearchers analyzed 14 years of physical activity and blood pressure records from 3,093 US adults and found that higher daily step counts were associated with better performance on tests of attention, cognitive control, and reward-related decision-making. Higher systolic blood pressure was associated with poorer delay-discounting performance, but accounted for only 4. Epilepsy linked to higher risk of young-onset dementia https://www.news-medical.net/news/20261014/Epilepsy-linked-to-higher-risk-of-young-onset-dementia.aspx?utm_source=news_medical_newsletter&utm_medium=email&utm_campaign=neurology_and_neuroscience_newsletter_21_october_2026 Epilepsy linked to higher risk of young-onset dementiaPeople with epilepsy may be more likely to develop young-onset dementia than people without epilepsy, according to a study published October 14, 2026, in Neurology®, the medical journal of the American Academy of Neurology. Hybrid AI architecture improves seizure prediction using EEG signals https://www.news-medical.net/news/20261013/Hybrid-AI-architecture-improves-seizure-prediction-using-EEG-signals.aspx?utm_source=news_medical_newsletter&utm_medium=email&utm_campaign=neurology_and_neuroscience_newsletter_21_october_2026 Hybrid AI architecture improves seizure prediction using EEG signalsEpilepsy affects about 50 million people worldwide and can seriously affect patients' quality of life. Electroencephalography (EEG), which records the brain's electrical activity in real time, plays an important role in epilepsy diagnosis and monitoring. Recurrent brain tumors undergo unique genetic changes after treatment https://www.news-medical.net/news/20261014/Recurrent-brain-tumors-undergo-unique-genetic-changes-after-treatment.aspx?utm_source=news_medical_newsletter&utm_medium=email&utm_campaign=neurology_and_neuroscience_newsletter_21_october_2026 Recurrent brain tumors undergo unique genetic changes after treatmentWhen patients are diagnosed with certain brain tumors, one of the biggest unanswered questions is what happens when the cancer returns. 16-year study links worsening vision to higher dementia risk https://www.news-medical.net/news/20261011/16-year-study-links-worsening-vision-to-higher-dementia-risk.aspx?utm_source=news_medical_newsletter&utm_medium=email&utm_campaign=neurology_and_neuroscience_newsletter_21_october_2026 16-year study links worsening vision to higher dementia riskResearchers followed 15,576 older adults in Hong Kong for up to 16 years and linked moderate to severe visual impairment to higher dementia risk, with rapid visual decline strengthening the association at poorer levels of vision. They estimated that severe impairment corresponded to 2.1 fewer dementia-free years over the study period, but could not establish that correcting vision prevents dementia. Study finds both the liver and brain drive distinct symptoms of rare genetic epilepsy https://www.news-medical.net/news/20261009/Study-finds-both-the-liver-and-brain-drive-distinct-symptoms-of-rare-genetic-epilepsy.aspx?utm_source=news_medical_newsletter&utm_medium=email&utm_campaign=neurology_and_neuroscience_newsletter_21_october_2026 Study finds both the liver and brain drive distinct symptoms of rare genetic epilepsyA recent study from Johns Hopkins Medicine reveals that both the liver and brain contribute pathways to differing symptoms of the same rare inherited disorder. Routine blood test may offer clues to future dementia risk https://www.news-medical.net/news/20261009/Routine-blood-test-may-offer-clues-to-future-dementia-risk.aspx?utm_source=news_medical_newsletter&utm_medium=email&utm_campaign=neurology_and_neuroscience_newsletter_21_october_2026 Routine blood test may offer clues to future dementia riskA common blood test already carried out during routine health checks may contain clues about a person's long-term risk of dementia, according to research being presented at the ECNP Congress in Munich and recently published in the Journal of Alzheimer's Disease. Study uncovers a protective role for microglia in Parkinson's disease https://www.news-medical.net/news/20261007/Study-uncovers-a-protective-role-for-microglia-in-Parkinsons-disease.aspx?utm_source=news_medical_newsletter&utm_medium=email&utm_campaign=neurology_and_neuroscience_newsletter_21_october_2026 Study uncovers a protective role for microglia in Parkinson's diseaseResearchers at the University of Oxford have uncovered a previously unrecognized protective role for microglia, the brain's resident immune cells, in Parkinson's disease. Study reveals how different plant saponins alleviate ischemic stroke https://www.news-medical.net/news/20261012/Study-reveals-how-different-plant-saponins-alleviate-ischemic-stroke.aspx?utm_source=news_medical_newsletter&utm_medium=email&utm_campaign=neurology_and_neuroscience_newsletter_21_october_2026 Study reveals how different plant saponins alleviate ischemic strokeIschemic stroke accounts for approximately 85% of all strokes and remains a major cause of death and long-term disability. Study links abnormal immature astroglia to lower fluid intelligence in older epilepsy patients https://www.news-medical.net/news/20261020/Study-links-abnormal-immature-astroglia-to-lower-fluid-intelligence-in-older-epilepsy-patients.aspx?utm_source=news_medical_newsletter&utm_medium=email&utm_campaign=neurology_and_neuroscience_newsletter_21_october_2026 Study links abnormal immature astroglia to lower fluid intelligence in older epilepsy patientsA new USC-led study links abnormal immature astroglia, star-shaped cells that support brain function, to lower fluid intelligence, or the ability to solve new problems, in older adults with epilepsy. Adults with ADHD face higher risk of developing dementia later in life https://www.news-medical.net/news/20261007/Adults-with-ADHD-face-higher-risk-of-developing-dementia-later-in-life.aspx?utm_source=news_medical_newsletter&utm_medium=email&utm_campaign=neurology_and_neuroscience_newsletter_21_october_2026 Adults with ADHD face higher risk of developing dementia later in lifeA new study led by University of Pittsburgh School of Medicine researchers finds that adults with attention-deficit/hyperactivity disorder (ADHD) face a significantly higher risk of developing dementia or mild cognitive impairment later in life.

Plasma eMTBR-Tau: Advancing Blood-Based Tau Tangle Research

https://spear.bio/resource/blog/plasma-emtbr-tau-tangle-biomarker/?utm_source=news_medical_newsletter&utm_medium=email&utm_campaign=neurology_and_neuroscience_newsletter_21_october_2026 Explore how plasma eMTBR-Tau complements pTau 217 in Alzheimer’s research. Discover findings generated using Spear Bio’s SPEAR TrueDetect™ eMTBR-Tau assay, linking blood measurements to autopsy-confirmed tau pathology, tau PET, and cognitive decline—with strong classification performance across blood samples collected up to a decade before death.

Women and men face different heart attack risks with diabetes

https://www.news-medical.net/news/20261023/Women-and-men-face-different-heart-attack-risks-with-diabetes.aspx A study spanning four decades reveals how cholesterol abnormalities and high blood pressure help explain differences in diabetes-related heart attack risk between women and men, with warning signs emerging years before diabetes is diagnosed. A study published in European Heart Journal Open reported that the relative increase in myocardial infarction, or heart attack, risk associated with diabetes was similar in women and men after adjustment for conventional cardiovascular risk factors. The initially observed sex difference narrowed after adjustment for these factors, whose combined contribution was greater in women than in men.

Maqui Berry: Health Benefits, Nutrition, and Uses (+++)

Maqui Berry: Health Benefits, Nutrition, and Uses https://www.news-medical.net/health/Maqui-Berry-Health-Benefits-Nutrition-and-Uses.aspx From its purple pigments to its interactions with gut bacteria, maqui berry raises scientific questions about how plant compounds influence cellular defenses and human health. The maqui berry, which grows in the temperate rainforests of southern Chile and Argentina, has a higher anthocyanin content than many other berries.1,9 Historically, Mapuche communities in southern Chile used maqui preparations, particularly those made from leaves, for wound care and fever, with modern researchers increasingly exploring this fruit as a source of antioxidant compounds.1 Jaboticaba Fruit: What Are Its Potential Health Benefits? https://www.news-medical.net/health/Jaboticaba-Fruit-What-Are-Its-Potential-Health-Benefits.aspx Beneath jaboticaba’s dark-purple skin lies a mixture of fiber and plant compounds that raises questions about digestion, blood sugar, and the gap between laboratory findings and human health. Jaboticaba is a dark-purple fruit that grows directly on the trunks and branches of trees native to the Brazilian Atlantic Forest. Emerging evidence suggests that anthocyanins, ellagitannins, and other bioactive compounds in jaboticaba may influence inflammatory pathways and the gut microbiota, primarily in laboratory and animal studies.1,3,7 How GLP-1 Drugs Affect the Brain Beyond Weight Loss https://www.news-medical.net/health/How-GLP-1-Drugs-Affect-the-Brain-Beyond-Weight-Loss.aspx What happens when a metabolic treatment reaches the brain's appetite, reward, and memory systems? Researchers are examining where these effects begin and what they could mean for neurological care. Glucagon-like peptide-1 (GLP-1) receptor agonists (RAs) were initially designed to improve glycemic control in people with type 2 diabetes. Research now suggests that these drugs may also influence mood, reward processing, cognition, and processes implicated in neurodegenerative diseases.1

Scientists studied one million immune cells and found clues to future disease risk

https://www.news-medical.net/news/20261022/Scientists-studied-one-million-immune-cells-and-found-clues-to-future-disease-risk.aspx A sweeping analysis of the body's most abundant white blood cells examines how their molecular differences relate to serious illness, metabolic health, and the risk of future disease. A recent study published in the journal Nature Immunology presents a single-cell atlas of human neutrophils (SCAHN), offering new insights into how these immune cells behave in health and disease. The researchers linked neutrophil gene activity patterns to cancer outcomes, metabolic health, and the risk of death over the long term. These patterns also helped identify mortality risk among individuals with acute illness at hospital presentation. The findings suggest that neutrophil profiling may eventually contribute to clinical risk assessment, pending prospective validation.