Study reveals why aging makes the body more vulnerable to breast cancer

https://www.news-medical.net/news/20260515/Study-reveals-why-aging-makes-the-body-more-vulnerable-to-breast-cancer.aspx Researchers at Georgetown's Lombardi Comprehensive Cancer Center have identified a mechanism that may help explain a key reason why older people experience worse outcomes from breast cancer.

GLP-1 weight loss medications linked to significant drop in asthma flares

https://www.news-medical.net/news/20260515/Study-Links-Use-Of-New-Obesity-Drugs-To-Reduction-Of-Asthma-Exacerbations-And-Inhaler-Use.aspx New research presented at this year's European Congress on Obesity in Istanbul, Turkey (12-15 May) shows the use of the new GLP-1 class of obesity drugs in people with asthma is associated with a 26 % fall in the number of asthma exacerbations and a 14 % drop in use of asthma inhaler reliever use. The study is by Simon Høj and Dr Kjell Erik Julius Håkansson, Copenhagen University Hospital, Copenhagen, Denmark, and colleagues.

Rocket Science Health validates targeted olfactory-cleft deposition in non-human primates ahead of the 4th Nasal Formulation & Delivery Summit

https://www.news-medical.net/news/20260515/Rocket-Science-Health-validates-targeted-olfactory-cleft-deposition-in-non-human-primates-ahead-of-the-4th-Nasal-Formulation-Delivery-Summit.aspx As the pace of modern drug discovery accelerates, the industry is increasingly recognizing that a breakthrough molecule is only as effective as its ability to reach the target site. Nowhere is this challenge more acute than in treating Central Nervous System (CNS) and brain-related illnesses, where the blood-brain barrier remains a formidable obstacle to traditional delivery. Today, the "how" of drug delivery is becoming as strategically critical as the "what," driving a shift toward innovative routes of administration - such as the intranasal delivery of vaccines and therapeutics - to bypass systemic barriers and improve patient outcomes.

Addressing depression and anxiety in primary care improves chronic pain management

https://www.news-medical.net/news/20260515/Addressing-depression-and-anxiety-in-primary-care-improves-chronic-pain-management.aspx A study published this month in the American Journal of Managed Care explores how integrating behavioral health care into primary care can improve outcomes and be cost-effective for adults with depression, anxiety and chronic pain who are on long-term opioid therapy.

Psilocybin offers fast-acting alternative to traditional antidepressants

https://www.news-medical.net/news/20260515/Psilocybin-offers-fast-acting-alternative-to-traditional-antidepressants.aspx A single dose of the psychedelic substance psilocybin can provide rapid relief from depressive symptoms – within just a few days. This is shown by the first randomized, double-blind study in Sweden of psilocybin for depression. The effect persisted for over three months, according to researchers at Karolinska Institutet.

Endoscopic sleeve gastroplasty outperforms oral semaglutide in short-term weight loss

https://www.news-medical.net/news/20260515/Endoscopic-sleeve-gastroplasty-outperforms-oral-semaglutide-in-short-term-weight-loss.aspx A comparative study, presented at ESGE Days 2026, has found that endoscopic sleeve gastroplasty (ESG) is associated with significantly greater short-term weight loss than oral semaglutide in adults with obesity.

Multi-institutional trial explores new lifeline for advanced prostate patients

https://www.news-medical.net/news/20260515/Multi-institutional-trial-explores-new-lifeline-for-advanced-prostate-patients.aspx For men with advanced prostate cancer that no longer responds to standard hormone therapies, treatment options are limited – and time matters. As the disease progresses, the window for effective, less intensive treatments begins to close.