CIENCIASMEDICASNEWS

Precision prevention and early detection: framework for a new clinical cancer control pathway Timothy R Rebbeck, PhD

https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(26)01669-7/abstract?utm_medium=email&dgcid=hubspot_email_conferencealerts_gr-lancet-lecture26&_hsenc=p2ANqtz--Zja4mPwYX1bDFY_c0omWOjl3L3AblFELZJx9hSYr1Ss6ww8HdpUCfHdV5dtSeZHbk9rvUHYcPiPfUJRuCQ7AQi57IOw&_hsmi=439507210&utm_content=439507210&utm_source=hs_email The Lecture was presented earlier today at the inaugural Gustave Roussy–The Lancet Lecture Series on Cancer Breakthroughs given by the author, Timothy Rebbeck. It explores the full potential of precision cancer prevention, including how risk-stratified approaches can help identify the right person, time, and intervention to prevent cancer. Stage at diagnosis remains the strongest determinant of cancer survival, yet only 13% of cancers are detected through guideline-based screening, and 20–50% first present in an emergency department. Precision prevention and early detection (PPED) tailors cancer control by asking who is at elevated risk of developing cancer, what preventive intervention is appropriate, when should intervention be applied and at what intensity, and how and where preventive services should be delivered. De-escalation of preventive interventions in low-risk individuals is as important as preventive care escalation in high-risk individuals. The hereditary cancer syndromes demonstrate that this logic works when cancer risk is sufficiently enriched. Although the science must continue to mature, the health-system infrastructure and workforce required to sustain longitudinal prevention planning are a defining cancer control challenge in the next decade.

Discontinuation of β-blockers in stable patients with previous myocardial infarction, preserved left ventricular ejection fraction, and no heart failure: a pooled analysis of individual patient data

Discontinuation of β-blockers in stable patients with previous myocardial infarction, preserved left ventricular ejection fraction, and no heart failure: a pooled analysis of individual patient data Prof Johanne Silvain, MD PhDa,* Send email to johanne.silvain@aphp.fr ∙ Prof Ki Hong Choi, MD PhDb,* ∙ Victorien Monguillon, MDa ∙ Prof Danbee Kang, MD PhDc ∙ Prof Guillaume Cayla, MD PhDd ∙ Prof Weon Kim, MD PhDe ∙ et al. https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(26)01426-1/abstract?dgcid=raven_jbs_etoc_feature_lancet

Wildfire smoke and health: current evidence, mechanisms, and future challenges Gongbo Chen, PhDa ∙ Rongbin Xu, PhDb,c ∙ Pei Yu, PhDa,d ∙ Yanming Liu, PhDa ∙ Prof Sarah B Henderson, PhDe ∙ Prof Fay H Johnston, PhDf ∙ et al.

Wildfire smoke and health: current evidence, mechanisms, and future challenges Gongbo Chen, PhDa ∙ Rongbin Xu, PhDb,c ∙ Pei Yu, PhDa,d ∙ Yanming Liu, PhDa ∙ Prof Sarah B Henderson, PhDe ∙ Prof Fay H Johnston, PhDf ∙ et al. https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(26)01601-6/fulltext?dgcid=raven_jbs_etoc_feature_lancet

The unmet needs of people living with severe asthma The Lancet (++...)

The unmet needs of people living with severe asthma The Lancet https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(26)01904-5/fulltext?dgcid=raven_jbs_etoc_email Sep 19, 2026 Volume 408Number 10560p1061-1146 https://www.thelancet.com/journals/lancet/issue/vol408no10560/PIIS0140-6736(26)X2035-9

Can maternal diet prevent infant food allergy? A large trial puts eggs and peanuts to the test

https://www.news-medical.net/news/20260917/Can-maternal-diet-prevent-infant-food-allergy-A-large-trial-puts-eggs-and-peanuts-to-the-test.aspx Australian researchers tested whether greater exposure to egg and peanut before birth and during breastfeeding could help shape food tolerance before infants begin eating these allergens themselves. A large randomized trial published in the New England Journal of Medicine found that increasing maternal consumption of eggs and peanuts during pregnancy and breastfeeding did not significantly reduce the risk of egg or peanut allergy in infants at 1 year of age who had a strong family history of allergic disease.