Semaglutide Use and Risk for Depression Show No Clear Association

https://www.medscape.com/viewarticle/semaglutide-use-and-risk-depression-show-no-clear-2026a1000s4u?src= The use of semaglutide was not associated with an increased risk for depression compared with placebo or other antidiabetic/antiobesity agents, but the evidence was limited and of very low certainty.

Cannabis Use May Increase Fall Risk in Adults With HIV

https://www.medscape.com/viewarticle/cannabis-use-may-increase-fall-risk-adults-hiv-2026a1000s50?src= Cannabis use in the past month was associated with a higher risk for falls among adults living with HIV. However, after adjusting for other substance use, prescribed medications, and comorbidities, the association was no longer statistically significant.

Adrenal Incidentalomas: When to Worry and What to Test F. Watto, MD; Paul N. Williams, MD

https://www.medscape.com/viewarticle/adrenal-incidentalomas-when-worry-and-what-test-2026a1000r3r?src=

Understanding the 'Wait Time Paradox' in Ovarian Cancer Dr Maurie Markman

https://www.medscape.com/viewarticle/understanding-wait-time-paradox-ovarian-cancer-2026a1000puk?src=

Fact or Fiction: Multiple Sclerosis Diagnosis and Workup Reviewed by Christopher C. Luzzio, MD

https://reference.medscape.com/viewarticle/fact-or-fiction-multiple-sclerosis-diagnosis-and-workup-2026a1000nsr?src=&_gl=1*667rps*_gcl_aw*R0NMLjE3ODM4NzAxMzguQ2p3S0NBanc5c3pTQmhCTkVpd0FDNTdTcTJZUXZTZkkxc01raEZQZ1VLSWRQZkVUdGU4U212WEI0NGh3aEE5WmMtVDhTSVBEWlBzNmdSb0NiT1FRQXZEX0J3RQ..*_gcl_au*NjkzMDY5MjIxLjE3ODA2NzA2MDAuMTY4MzI1MDM3LjE3ODY5NzI2OTIuMTc4Njk3NDg1Mi4yMTI0OTM5ODg4LjE3ODY4OTIyNTQuMTc4Njk3NDg1Mg.. The 2024 revision of the McDonald criteria has substantially refined how clinicians diagnose multiple sclerosis (MS), placing greater emphasis on robust imaging and cerebrospinal fluid (CSF)-based evidence. The updated framework incorporates new MRI biomarkers, revised CSF parameters, and tailored guidance for specific patient subgroups, such as individuals with radiologically isolated syndrome (RIS) and older adults.

Mastectomy Preserves Ventriculoperitoneal Shunt in Woman

https://www.medscape.com/viewarticle/mastectomy-preserves-ventriculoperitoneal-shunt-woman-2026a1000s45?src= Preserving a ventriculoperitoneal (VP) shunt during breast cancer surgery may be feasible when the tumor is close to the catheter and shunt dependence precludes removal. This case demonstrated that careful preoperative imaging, multidisciplinary planning, avoidance of energy devices near the catheter, and meticulous sharp dissection allowed the shunt to be preserved during mastectomy without damage or subsequent complications.

Fast Five Quiz: Psoriasis and Pregnancy Reviewed by Shari Lipner, MD, PhD

https://reference.medscape.com/viewarticle/psoriasis-and-pregnancy-2026a1000oia?src=&_gl=1*o84t4p*_gcl_aw*R0NMLjE3ODM4NzAxMzguQ2p3S0NBanc5c3pTQmhCTkVpd0FDNTdTcTJZUXZTZkkxc01raEZQZ1VLSWRQZkVUdGU4U212WEI0NGh3aEE5WmMtVDhTSVBEWlBzNmdSb0NiT1FRQXZEX0J3RQ..*_gcl_au*NjkzMDY5MjIxLjE3ODA2NzA2MDAuMTY4MzI1MDM3LjE3ODY5NzI2OTIuMTc4Njk3NDg1Mi4yMTI0OTM5ODg4LjE3ODY4OTIyNTQuMTc4Njk3NDg1Mg.. Because psoriasis can affect female patients during their reproductive years, pregnancy commonly overlaps with ongoing disease management. Clinical care during pregnancy focuses on balancing maternal disease control with fetal safety using evidence-based treatment decisions and including multidisciplinary input when needed.