Clinicopathological characteristics and health care for Tibetan women with breast cancer: a cross-sectional survey

Yulan Zhao†,
Hanhuan Luo†,
Xintian Zhang,
Tashi Bianba,
Lin Li,
Qian Wang,
Lei Guo,
Dian Wang,
Yongge ZeEmail author and
Shan ZhengEmail author View ORCID ID profile

†Contributed equally

BMC Cancer201919:380

https://doi.org/10.1186/s12885-019-5580-x

Received: 14 March 2018
Accepted: 4 April 2019
Published: 25 April 2019

Open Peer Review reports

Abstract

Background

The healthcare system (HCS) improved in Tibet Autonomous Region (TAR), China. The present study aimed to investigate whether these improvements might alter the clinicopathological characteristics of a Tibetan female with breast cancer (BC) in TAR.

Methods

This was a single-center cross-sectional study conducted at TAR People’s Hospital. All Tibetan adult women were treated for BC in this hospital between January 1, 1973 and December 31, 2015. The inclusion criteria were as follows: (1) Tibetan adult woman living in Tibet; (2) Histopathology or cytopathology or both confirming primary BC; (3) All the treatments were finished in this hospital. χ2test and logistic regression were applied, using age group and census register as the two covariates.

Results

A total of 273 patients with BC were included in the final analysis. Of these, 14 patients were in the free HCS, 183 patients had medical insurance combined with a new rural cooperative HCS, and 76 were in a rural and urban integration HCS. Currently, a rural and urban integration HCS is an improved system. Consequently, an increase in the proportion patients in the T1–3 stage was observed (0.198; 0.046 to 0.852) between the rural and urban integration HCS and free HCS. The proportion of patients in early (I + II) stage cancer (0.110; 0.019–0.633) also increased between these two HCSs.

Conclusion

This was the first report about Tibetan women with BC in Tibet. Some clinicopathological characteristics at the presentation of Tibetan women with BC may improve during different HCSs. The cancer awareness, early detection, and the overall management in patients with advanced stage BC might improve the prognosis of BC in the rural and urban integration HCS.