Commissioned by the Alpha One Foundation in collaboration with COPD Support Ireland and funded by the Health Research Board, this educational film describes the genetic condition alpha-1 antitrypsin deficiency (Alpha-1 for short). People born with Alpha-1 do not produce enough alpha-1 antitrypsin, an important protein which protects the lungs. They therefore have increased risk for the lung disease chronic obstructive pulmonary disease (COPD). 1 in 25 Irish people carry the defective gene that causes Alpha-1. For more information see www.alpha1.ie.