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Retrovirology

First Phase I human clinical trial of a killed whole-HIV-1 vaccine: demonstration of its safety and enhancement of anti-HIV antibody responses

Combination of nanoparticle-based therapeutic vaccination and transient ablation of regulatory T cells enhances anti-viral immunity during chronic retroviral infection

Intradermal injection of a Tat Oyi-based therapeutic HIV vaccine reduces of 1.5 log copies/mL the HIV RNA rebound median and no HIV DNA rebound following cART interruption in a phase I/II randomized controlled clinical trial

1. REVIEW

   A conflict of interest: the evolutionary arms race between mammalian APOBEC3 and lentiviral Vif

   Yusuke Nakano, Hirofumi Aso, Andrew Soper, Eri Yamada, Miyu Moriwaki, Guillermo Juarez-Fernandez, Yoshio Koyanagi and Kei Sato

   Published on: 8 May 2017
2. EDITORIAL

   Professor Mark Wainberg

   Monsef Benkirane, Ben Berkhout, Persephone Borrow, Ariberto Fassati, Masahiro Fujii, J. Victor Garcia, Paul Gorry, Andrew Lever, Johnson Mak, Monique Nijhuis, Klaus Strebel, Francois Venter and Robin Weiss

   Published on: 5 May 2017
3. RESEARCH

   Highly divergent patterns of genetic diversity and evolution in proviral quasispecies from HIV controllers

   Suwellen S. D. de Azevedo, Diogo Gama Caetano, Fernanda H. Côrtes, Sylvia L. M. Teixeira, Karina dos Santos Silva, Brenda Hoagland, Beatriz Grinsztejn, Valdilea G. Veloso, Mariza G. Morgado and Gonzalo Bello

   Published on: 2 May 2017
4. SHORT REPORT

   Interference of retroviral envelope with vaccine-induced CD8+ T cell responses is relieved by co-administration of cytokine-encoding vectors

   Nadine Bongard, Dennis Lapuente, Sonja Windmann, Ulf Dittmer, Matthias Tenbusch and Wibke Bayer

   Published on: 27 April 2017
5. RESEARCH

   Molecular mechanisms by which HERV-K Gag interferes with HIV-1 Gag assembly and particle infectivity

   Kazuaki Monde, Hiromi Terasawa, Yusuke Nakano, Ferri Soheilian, Kunio Nagashima, Yosuke Maeda and Akira Ono

   Published on: 26 April 2017

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Featured conference proceedings:

Frontiers of Retrovirology 2016 – complex retroviruses, retroelements and their hosts took place in September 2016 in Erlangen, Germany.

Read the full proceedings of the meeting's oral presentations, covering topics from 'innate sensing and intrinsic immunity' to 'adaptive immunity' and 'recent advances in HIV vaccine development'.

Read more