domingo, 8 de enero de 2017

Statin Prescription Rates for Patients With Dyslipidemia | Cardiology | JAMA Cardiology | The JAMA Network

Statin Prescription Rates for Patients With Dyslipidemia | Cardiology | JAMA Cardiology | The JAMA Network

Rate of Statin Prescription in Younger Patients With Severe Dyslipidemia

JAMA Cardiol. Published online January 4, 2017. doi:10.1001/jamacardio.2016.5162

Cardiovascular disease affects 1 in 3 patients and remains the leading cause of death in the United States.1 Severe elevation of low-density lipoprotein cholesterol (LDL-C) levels is a modifiable risk factor for developing premature cardiovascular disease, and elevation levels of 190 mg/dL or greater (to convert LDL-C values to millimoles per liter, multiply by 0.0259) may indicate a monogenic etiology such as familial hypercholesterolemia.2 Treatment with 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors or statins is recommended (class IA) for all adults 21 years or older with an LDL-C of 190 mg/dL or greater. Statin treatment appears to reduce mortality and result in cost savings for health systems.3,4 Therefore, we sought to examine rates of statin prescription in patients screened for dyslipidemia to identify treatment gaps in a real-world contemporary setting.

Public Health Genomics Knowledge Base (v1.2)
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Last Posted: Jan-06-2017 0PM

Last Posted: Jan 06, 2017

Most Recent Scientific Publications from Weekly Horizon Scans

From Genomics & Health Impact Scan Database
This database includes published scientific literature on evidence-based translation of genomic discoveries into improved health care and disease prevention that have a potential impact on population health.

From CDC Information Database
This database includes general CDC public health information on specific diseases and health related topics. When available, the database displays genomic information from various CDC web pages. Users are also encouraged to conduct searches of CDC website for additional information.

From CDC-Authored Genomics Publication Database
This database contains CDC-authored publications in public health genomics including infectious diseases, newborn screening, reproductive health, genetic testing, cancer, chronic diseases, birth defects and developmental disabilities, environmental and occupational health as well as laboratory, bioinformatics and statistical methods.

From Implementation Database
This database focuses on state and national activities that integrate genomics into public health programs and clinical practice

From Guideline Database
This database contains updated guidelines, policies and recommendations on genomic research and practice, as provided by professional organizations, federal advisory groups, expert panels and policy groups.

From Tier Table Database
CDC Office of Public Health Genomics (OPHG) conducts horizon scanning (a systematic research method to find and follow novel technologies appearing in the literature) to identify and track the progress of genomic tests as they move from research into clinical and public health practice. As an aid in organizing horizon scanning results, OPHG ranks genomic tests, and family health history applications, by levels of evidence. See detail.

From HuGE Literature Finder Database
This database contains published literature on genetic associations and other human genome epidemiology

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