CIENCIASMEDICASNEWS: How Should Freezer and Fridge Temperatures be Monitored for Research?

martes, 2 de abril de 2019

How Should Freezer and Fridge Temperatures be Monitored for Research?

	April 2, 2019
	Biochemistry
	The latest biochemistry news from AZoNetwork

How Should Freezer and Fridge Temperatures be Monitored for Research?
The materials held in cold storage by biology and pharma labs can be worth tens of thousands of dollars, and it is vital that these remain at a sufficiently low temperature in order to avoid being rendered unusable. In some instances, the samples stored in freezers cannot be assigned a simple monetary value. In the USA in 2018, two separate fertility clinics suffered cryo failures, resulting in the loss of thousands of embryos and eggs stored for those hoping to have children.

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			Young scientists develop cheap and simple catalyst system for organic synthesis The removal of carboxyl groups and the release of alkyl radical fragments from the tight binding of carboxyl groups are one of the most interesting and promising directions in organic synthesis, especially in the field of new drug synthesis.

			Importance of Differentiating Between Leucine and Isoleucine As the name might suggest, isoleucine is, in fact, an isomer of leucine. This means that both amino acids have the same molecular formula but differ in structure. Importantly, the two isomers interact differently with other amino acids within mammalian cells. Hence, being able to identify and differentiate between leucine and isoleucine is essential.

	Binding affinities of PFASs to Baikal seal PPARα revealed using in vitro and in silico approaches A team of researchers at Ehime University revealed the binding affinities of perfluoroalkyl substances (PFASs) to Baikal seal peroxisome proliferator-activated receptor α (PPARα) using in vitro and in silico approaches.

	USP15 enzyme could potentially lead to new treatments for breast, pancreatic cancer Researchers at the George Washington University Cancer Center found that the enzyme USP15 could potentially lead to new treatments for breast and pancreatic cancer. Their findings were published in Nature Communications.

	Electrochemistry Mass Spectrometry (EC-MS) Applications EC-MS can be used to analyze a wide range of biological reaction. In this technique, electrochemistry is used to determine the concentration or chemical reactivity of a substance by measuring either the potential, charge, or current. Mass spectrometry is then applied to further characterize these analytes.

	Importance of Measuring pH in Industry Most products require a specific pH for activity or stability, especially in the food and beverage industry, cosmetic industry and pharmaceutical sector. Thus, the industrial applications of pH meters are huge, ranging from water conditioning to food production.

	Overview of the Isoelectric Point (pI) The isoelectric point (pI) is the point at which the net charge on a molecule is zero. pI is most commonly examined for proteins. Each of the amino acids in a protein carries a distinct charge, and the overall charge of a protein is the summation of the individual charges on each amino acid. This charge is also dependent on the pH of the surrounding solution.