domingo, 15 de julio de 2018

Precision medicine applications in prostate cancer. - PubMed - NCBI

2018 Jun 18;10:1758835918776920. doi: 10.1177/1758835918776920. eCollection 2018.

Precision medicine applications in prostate cancer.

McCrea EM1, Lee DK2, Sissung TM3, Figg WD4.

Author information

Abstract

Aided by developments in diagnostics and therapeutics, healthcare is increasingly moving toward precision medicine, in which treatment is customized to each individual. We discuss the relevance of precision medicine in prostate cancer, including gene targets, therapeutics and resistance mechanisms. We foresee precision medicine becoming an integral component of prostate cancer management to increase response to therapy and prolong survival.

KEYWORDS:

AR-V7; androgen deprivation therapy resistance; microsatellite instability; organic anion transporting polypeptide 1B3; precision medicine; sex determining region Y box2