Association of Rhinovirus C Bronchiolitis and Immunoglobulin E Sensitization During Infancy With Development of Recurrent Wheeze. | Asthma | JAMA Pediatrics | JAMA Network

Association of Rhinovirus C Bronchiolitis and Immunoglobulin E Sensitization During Infancy With Development of Recurrent Wheeze. | Asthma | JAMA Pediatrics | JAMA Network

Monday, April 1, 2019

NIAID-Supported Study Links Rhinovirus-C Bronchiolitis and Early Sensitivity to Allergens with Risk for Recurrent Wheeze

Bronchiolitis is a common illness in young children caused by a viral infection in the lungs that makes it difficult to breathe. The illness is associated with a high risk for asthma later in childhood. A NIAID-supported study published today in JAMA Pediatrics found that among infants with severe bronchiolitis, those with rhinovirus-C infection plus a positive test for allergies had a 3-fold higher risk of recurrent wheeze by age 3 years compared to those either without allergy or with RSV infection. The investigators are following the children in the study through age 6 to find out whether the same risk factors will be associated with asthma.