Advanced Molecular Detection Clips
About Advanced Molecular Detection Clips
Clips are selected weekly from a variety of sources, including PubMed, journal tables of contents, and online media. Special emphasis is given to the use of next-generation genetic sequencing in infectious disease public health surveillance, investigation, and development of new diagnostics and interventions. The collection is not comprehensive but aims to capture highlights, while surveying a wide range of topics. CDC-authored articles are flagged. Items marked I&E address aspects of implementation or evaluation in clinical or public health practice.
Advanced Molecular Detection Clips Content
NEWS
- Germ Sleuths Go High-Tech as Labs Get Illumina Sequencers
Bloomberg Tech, June 9, 2016. - CDC Researchers Launch Database of Population Genomics, Clinical Data
GenomeWeb, Jun 14, 2016. - Canada launches review of its research enterprise
Kondro W. Science, Jun 13, 2016. - Mapping Zoonotic Disease
Akst J. The Scientist, Jun 14, 2016. - Researcher Accidentally Infects Self with Zika
Offord C. The Scientist, Jun 14, 2016. - Researchers track Zika on ‘road trip’ through Brazil
Healio, June 13, 2016. - Banking on stool despite an uncertain future
Amirtha T. Science, Jun 10, 2016. - Early-Life Microbiome
Vence T. The Scientist, Jun 16, 2016. - CRISPR Antidotes Galore
Azvolinsky A. The Scientist, Jun 13, 2016. - Creating a DNA Record with CRISPR
Williams R. The Scientist, Jun 9, 2016. - Could CRISPR gene-cutting tool transform disease diagnostics?
Joseph A. STAT, Jun 10, 2016. - "Gene drive." Learn the term. Because it could one day transform the world.
Plumer B. Vox, Jun 12, 2016. - UCSD Team Wins $9.5M NIH Grant to Use Systems Biology to Tackle Antibiotic Resistance
Macron D. GenomeWeb, Jun 15, 2016. - Texas Biomed Team Awarded $3.5M to Study Genetics of Parasitic Drug Resistance
GenomeWeb, Jun 9, 2016.
EVENTS / TRAINING / WEB RESOURCES
- Tree Viewer 1.9 visualizes medium-large phylogenetic trees
(announcement) NCBI, Jun 10, 2016. - NCBI to hold hackathon on NIH campus in August
(announcement) NCBI, Jun 14, 2016. - Exit this survey 2016 Call for Nominations: ISDS Awards for Outstanding Research Articles in Biosurveillance
(announcement) International Society for Disease Surveillance. Nominations close Jun 24, 2016. - 2016 International Society for Disease Surveillance Annual Conference
(conference) Atlanta, GA, Dec 6-8, 2016. Abstract deadline Aug 26, 2016. - A knowledge base for tracking the impact of genomics on population health.
Yu Wei et al. Genetics in medicine : official journal of the American College of Medical Genetics 2016 Jun
CONCEPTS / COMMENTS
- Beyond the Ebola Battle - Winning the War against Future Epidemics.
Dzau Victor J et al. The New England journal of medicine 2016 Jun - The Unseen: Millions of microbes are yet to be discovered. Will one hold the ultimate cure?
Khatchadourian R. New Yorker, Jun 20, 2016. - The evolution of genome mining in microbes - a review.
Ziemert Nadine et al. Natural product reports 2016 Jun - Microbiology: The dark side of antibiotics
Sana TG, Monack DM. Nature, Jun 15, 2016. - Sharing is caring: international sharing of data enhances genomic surveillance of Listeria monocytogenes.
Kwong Jason C et al. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2016 Jun
METHODS / TOOLS
- Advancing microbial sciences by individual-based modelling
Hellweger , Nat Rev Microbiol, Jun 6, 2016. - Emerging concepts of data integration in pathogen phylodynamics.
Baele Guy et al. Systematic biology 2016 Jun - Genome Data Exploration Using Correspondence Analysis.
Tekaia Fredj et al. Bioinformatics and biology insights 2016 59-72 - Standards for Cell Line Authentication and Beyond.
Almeida Jamie L et al. PLoS biology 2016 Jun (6) e1002476 - Authentication: A Standard Problem or a Problem of Standards?
Capes-Davis Amanda et al. PLoS biology 2016 Jun (6) e1002477 - An Introduction to Programming for Bioscientists: A Python-Based Primer.
Ekmekci Berk et al. PLoS computational biology 2016 Jun (6) e1004867 - Northeast India Helminth Parasite Information Database (NEIHPID): Knowledge Base for Helminth Parasites.
Biswal Devendra Kumar et al. PloS one 2016 (6) e0157459
EVOLUTION / ECOLOGY / POPULATIONS
- Intra-host evolution of methicillin-resistant Staphylococcus aureus USA300 among individuals with reoccurring skin and soft tissue infections.
Azarian T et al. The Journal of infectious diseases 2016 Jun - Local Persistence of Novel MRSA Lineage after Hospital Ward Outbreak, Cambridge, UK, 2011-2013.
Toleman Michelle S et al. Emerging infectious diseases 2016 Sep (9) - Genomic Investigation Reveals Highly Conserved, Mosaic, Recombination Events Associated with Capsular Switching among Invasive Neisseria meningitidis Serogroup W Sequence Type (ST) - 11 Strains.
Mustapha Mustapha M et al. Genome biology and evolution 2016 Jun
- Bartonella melophagi in blood of domestic sheep (Ovis aries) and sheep keds (Melophagus ovinus) from the southwestern US: Cultures, genetic characterization, and ecological connections.
Kosoy Michael et al. Veterinary microbiology 2016 Jul 43-9 - Genome Structural Diversity among 31 Bordetella pertussis Isolates from Two Recent U.S. Whooping Cough Statewide Epidemics.
Bowden Katherine E et al. mSphere (3) - Zika virus: history of a newly emerging arbovirus.
Wikan Nitwara et al. The Lancet. Infectious diseases 2016 Jun - Detection of Plasmodium falciparum Infection in Anopheles squamosus (Diptera: Culicidae) in an Area Targeted for Malaria Elimination, Southern Zambia.
Stevenson Jennifer C et al. Journal of medical entomology 2016 Jun - Multigenomic Delineation of Plasmodium Species of the Laverania Subgenus Infecting Wild-living Chimpanzees and Gorillas.
Liu Weimin et al. Genome biology and evolution 2016 Jun - Decline in frequency of the 2La chromosomal inversion in Anopheles gambiae (s.s.) in Western Kenya: correlation with increase in ownership of insecticide-treated bed nets.
Matoke-Muhia Damaris et al. Parasites & vectors 2016 (1) 334 
PATHOGENICITY / ANTIMICROBIAL RESISTANCE
- Evolution, epidemiology and diversity of Corynebacterium diphtheriae: New perspectives on an old foe.
Sangal Vartul et al. Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases 2016 Jun 364-370 - Molecular evolution of Klebsiella pneumoniae ST278 harboring blaNDM-7 involved in nosocomial transmission.
Lynch T et al. The Journal of infectious diseases 2016 Jun - Emergence and genetic characteristics of pyrazinamide resistant tuberculosis in China, a multi-center study.
Li Dange et al. Antimicrobial agents and chemotherapy 2016 Jun - Zika Virus Infection with Prolonged Maternal Viremia and Fetal Brain Abnormalities.
Driggers Rita W et al. The New England journal of medicine 2016 Jun (22) 2142-51 - A broad analysis of resistance development in the malaria parasite.
Corey Victoria C et al. Nature communications 2016 11901
DETECTION / DIAGNOSIS
- Meta-analysis of the performance of a combined treponemal and non-treponemal rapid diagnostic test for syphilis and yaws.
Marks Michael et al. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2016 May - Evaluation of an optimal epidemiologic typing scheme for Legionella pneumophila with whole genome sequence data using validation guidelines.
David Sophia et al. Journal of clinical microbiology 2016 Jun - Whole genome sequence-based serogrouping of Listeria monocytogenes isolates.
Hyden Patrick et al. Journal of biotechnology 2016 Jun - Single-step multiplex PCR for determining 92 pneumococcal serotypes.
Marimón José M et al. Journal of clinical microbiology 2016 Jun - Genotyping and Axenic Growth of Coxiella burnetii Isolates Found in the United States Environment.
Kersh Gilbert J et al. Vector borne and zoonotic diseases (Larchmont, N.Y.) 2016 Jun - A Rapid Standardized Protein Extraction Method Using Adaptive Focused Acoustics for Identification of Mycobacteria by MALDI-ToF MS
Adams LL, et al. Diagn Microbiol Infect Dis, Jun 11, 2016. - Whole-genome sequencing of Mycobacterium tuberculosis for rapid diagnostics: feasibility of a decentralised model.
Martinez Elena et al. The Lancet. Respiratory medicine 2016 Apr (4) e13-e14 - Narrowing of the Diagnostic Gap of Acute Gastroenteritis in Children 0-6 Years of Age Using a Combination of Classical and Molecular Techniques, Delivers Challenges in Syndromic Approach Diagnostics.
Steyer Andrej et al. The Pediatric infectious disease journal 2016 Jun - Evaluation of the Whole Blood Alere Q NAT Point-of-Care RNA Assay for HIV-1 Viral Load Monitoring in a Primary Health Care Setting in Mozambique.
Jani Ilesh V et al. Journal of clinical microbiology 2016 Jun - Essentials of filoviral load quantification.
Cnops Lieselotte et al. The Lancet. Infectious diseases 2016 Jun
EPIDEMIOLOGY / OUTBREAKS / TRANSMISSION
- An outbreak of Shiga toxin-producing Escherichia coli serogroup O157 linked to a lamb-feeding event.
Rowell S et al. Epidemiology and infection 2016 Jun 1-7 - Common skin infection due to Panton-Valentine leucocidin-producing Staphylococcus aureus strains in asylum seekers from Eritrea: a genome-based investigation of a suspected outbreak.
Jaton L et al. Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 2016 Jun - Use of Whole Genome Sequencing and Patient Interviews To Link a Case of Sporadic Listeriosis to Consumption of Prepackaged Lettuce.
Jackson K A et al. Journal of food protection 2016 May (5) 806-9 - A Cluster of Paralytic Poliomyelitis Cases Due to Transmission of Slightly Diverged Sabin 2 Vaccine Poliovirus.
Korotkova Ekaterina A et al. Journal of virology 2016 Jul (13) 5978-88 - Transmitted HIV Drug Resistance High and Longstanding in Metropolitan Washington, D.C.
Kassaye S, et al. Clin Infect Dis, Jun 15, 2016. - Deep sequencing increases hepatitis C virus phylogenetic cluster detection compared to Sanger sequencing.
Montoya Vincent et al. Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases 2016 Jun 329-337 - Genetic diversity, seasonality and transmission network of human metapneumovirus: identification of a unique sub-lineage of the fusion and attachment genes.
Chow Wei Zhen et al. Scientific reports 2016 27730
ANTIMICROBIALS / VACCINES / INTERVENTIONS
- Directed vaccination against pneumococcal disease.
Li Yi et al. Proceedings of the National Academy of Sciences of the United States of America 2016 Jun - Novel high throughput pooled shRNA screening identifies NQO1 as a potential drug target for host directed therapy for tuberculosis.
Li Qing et al. Scientific reports 2016 27566
HOST-MICROBE INTERACTIONS
- Clinical and Epidemiological Evidence of the Red Queen Hypothesis in Pneumococcal Serotype Dynamics.
Stockmann Chris et al. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2016 Jun - Persistent gender disparities in invasive pneumococcal diseases in the conjugate vaccine era.
de St Maurice Annabelle et al. The Journal of infectious diseases 2016 May - Individual-specific changes in the human gut microbiota after challenge with enterotoxigenic Escherichia coli and subsequent ciprofloxacin treatment.
Pop Mihai et al. BMC genomics 2016 (1) 440 - Adipose tissue microbiota in humans: an open issue.
Zulian A et al. International journal of obesity (2005) 2016 Jun - Natural history of the infant gut microbiome and impact of antibiotic treatment on bacterial strain diversity and stabilit
M Yassour et al, Science Translational Medicine, June 16, 2016 - Antibiotics, birth mode, and diet shape microbiome maturation during early life
NA Bokulish et al, Science Translational Medicine, June 16, 2016 - Primary HCMV Infection in Pregnancy from Classic Data towards Metabolomics: an Exploratory analysis.
Fattuoni Claudia et al. Clinica chimica acta; international journal of clinical chemistry 2016 Jun - A Cross-Study Biomarker Signature of Human Bronchial Epithelial Cells Infected with Respiratory Syncytial Virus.
Gardinassi Luiz Gustavo et al. Advances in virology 2016 3605302 - Note: indicates that at least one CDC-affiliated author; indicates that the article addresses aspects of implementation or evaluation in clinical or public health practice.
Disclaimer: Articles listed in the Advanced Molecular Detection Clips are selected by the CDC Office of Public Health Genomics to provide current awareness of the scientific literature and news. Inclusion in the clips does not necessarily represent the views of the Centers for Disease Control and Prevention nor does it imply endorsement of the article's methods or findings. CDC and DHHS assume no responsibility for the factual accuracy of the items presented. The selection, omission, or content of items does not imply any endorsement or other position taken by CDC or DHHS. Opinion, findings and conclusions expressed by the original authors of items included in the Clips, or persons quoted therein, are strictly their own and are in no way meant to represent the opinion or views of CDC or DHHS. References to publications, news sources, and non-CDC Websites are provided solely for informational purposes and do not imply endorsement by CDC or DHHS.
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