ABCA7 polymorphisms correlate with memory impairment and default mode network in patients with APOE ε4-associated Alzheimer’s disease | Alzheimer's Research & Therapy | Full Text

ABCA7 polymorphisms correlate with memory impairment and default mode network in patients with APOE ε4-associated Alzheimer’s disease | Alzheimer's Research & Therapy | Full Text

Alzheimer's Research & Therapy

ABCA7 polymorphisms correlate with memory impairment and default mode network in patients with APOEε4-associated Alzheimer’s disease

Since both APOE and ABCA7 protein expression may independently reduce neuritic plaque burden and reorganize fibrillar amyloid burden-mediated disruption of functional connectivity in the default mode network, we ...

Authors:Ya-Ting Chang, Shih-Wei Hsu, Shu-Hua Huang, Chi-Wei Huang, Wen-Neng Chang, Chia-Yi Lien, Jun-Jun Lee, Chen-Chang Lee and Chiung-Chih Chang

Citation:Alzheimer's Research & Therapy 2019 11:103

Content type:Research

Published on: 12 December 2019

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