EphA4 loss improves social memory performance and alters dendritic spine morphology without changes in amyloid pathology in a mouse model of Alzheimer’s disease | Alzheimer's Research & Therapy | Full Text

EphA4 loss improves social memory performance and alters dendritic spine morphology without changes in amyloid pathology in a mouse model of Alzheimer’s disease | Alzheimer's Research & Therapy | Full Text

Alzheimer's Research & Therapy

EphA4 loss improves social memory performance and alters dendritic spine morphology without changes in amyloid pathology in a mouse model of Alzheimer’s disease

EphA4 is a receptor of the ephrin system regulating spine morphology and plasticity in the brain. These processes are pivotal in the pathophysiology of Alzheimer’s disease (AD), characterized by synapse dysfun...

Authors:Lindsay Poppe, Laura Rué, Mieke Timmers, Annette Lenaerts, Annet Storm, Zsuzsanna Callaerts-Vegh, Gilles Courtand, Antina de Boer, Silke Smolders, Philip Van Damme, Ludo Van Den Bosch, Rudi D’Hooge, Bart De Strooper, Wim Robberecht and Robin Lemmens

Citation:Alzheimer's Research & Therapy 2019 11:102

Content type:Research

Published on: 12 December 2019

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