Newly Published Reviews Collection!
Molecular Cancer is proud to finally present a curated selection of literature reviews titled Oncogenic Signaling of Tyrosine Kinase in Cancer: Challenges and Therapeutic Opportunities. The journal received more submissions for this thematic series than expected in December 2017, and we would like to thank all of our authors and readers for their excitement and participation throughout the editorial process. More information regarding the series is below:
The role of receptor tyrosine kinases (RTKs) in cancer began only about three decades ago; however, the amount of research and progress dedicated to the study of RTKs has been explosive, considering the vast quantity of known RTKs and their unique mechanisms in manipulating cellular signaling pathways. These articles report on all aspects related to expression, regulation and function of receptor tyrosine kinases (RTKs), non-receptor tyrosine kinases and other kinases in oncogenic signaling in cancer cells. The series aims to highlight significant and quality new findings related to targeted therapies, tyrosine kinase inhibitors (TKI), genetic and epigenetic mechanisms of acquired resistance to TKI, clinical trials and pre-clinical studies.