Genetic Testing Helps Guide Treatment in Prostate Cancer

Genetic Testing Helps Guide Treatment in Prostate Cancer

Danielle Bucco

Published: Wednesday, Mar 28, 2018

Veda Giri, MD

Genetic testing has created an impact in breast, ovarian, and prostate cancers, in terms of screening and therapeutic decisions for patients, explains Veda Giri, MD. The importance of genetics cannot only determine molecular mutations that can be targeted, but also who might be at risk for prostate cancer.

There are several mutations that have been identified and associated with prostate cancer in various studies, such as BRCA1/2, mismatch repair deficient (dMMR) genes, and HOXB13. A discovered mutation could lead to additional treatment options or enrollment on clinical trials that were previously not available for a patient.1