A knowledge base for tracking the impact of genomics on population health.

Yu W1, Gwinn M1,2, Dotson WD1, Green RF1,3, Clyne M4,5, Wulf A1,6, Bowen S1, Kolor K1, Khoury MJ1.

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Abstract

PURPOSE:

We created an online knowledge base (the Public Health Genomics Knowledge Base (PHGKB)) to provide systematically curated and updated information that bridges population-based research on genomics with clinical and public health applications.

METHODS:

Weekly horizon scanning of a wide variety of online resources is used to retrieve relevant scientific publications, guidelines, and commentaries. After curation by domain experts, links are deposited into Web-based databases.

RESULTS:

PHGKB currently consists of nine component databases. Users can search the entire knowledge base or search one or more component databases directly and choose options for customizing the display of their search results.

CONCLUSION:

PHGKB offers researchers, policy makers, practitioners, and the general public a way to find information they need to understand the complicated landscape of genomics and population health.Genet Med advance online publication 09 June 2016Genetics in Medicine (2016); doi:10.1038/gim.2016.63.