Preventive Medication: Aspirin for the Prevention of Cardiovascular Disease

Aspirin for the Prevention of Cardiovascular Disease
Release Date: March 2009

Summary of Recommendations / Supporting Documents
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Summary of Recommendations
The USPSTF recommends the use of aspirin for men age 45 to 79 years when the potential benefit due to a reduction in myocardial infarctions outweighs the potential harm due to an increase in gastrointestinal hemorrhage.
- Grade: A recommendation.
The USPSTF recommends the use of aspirin for women age 55 to 79 years when the potential benefit of a reduction in ischemic strokes outweighs the potential harm of an increase in gastrointestinal hemorrhage.
- Grade: A recommendation.
The USPSTF concludes that the current evidence is insufficient to assess the balance of benefits and harms of aspirin for cardiovascular disease prevention in men and women 80 years or older.
- Grade: I statement.
The USPSTF recommends against the use of aspirin for stroke prevention in women younger than 55 years and for myocardial infarction prevention in men younger than 45 years.
- Grade: D recommendation.
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Supporting Documents
Aspirin for the Prevention of Cardiovascular Disease, March 2009
* Recommendations and Rationale (PDF File, 335 KB; PDF Help)
* Supporting Article (PDF File, 160 KB; PDF Help)
* Evidence Synthesis (PDF File, 145 KB; PDF Help)
* Clinical Summary (PDF File, 114 KB; PDF Help)
Persons with disabilities experiencing problems accessing portions of the PDF file for this report should contact Marion Torchia at (301) 427-1399. The accessible version of the Evidence Synthesis will be available by April 15, 2009.
Current as of March 2009

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Preventive Medication: Aspirin for the Prevention of Cardiovascular Disease