Organotypic slice culture model demonstrates inter-neuronal spreading of alpha-synuclein aggregates | Acta Neuropathologica Communications | Full Text

Organotypic slice culture model demonstrates inter-neuronal spreading of alpha-synuclein aggregates | Acta Neuropathologica Communications | Full Text

Acta Neuropathologica Communications

Organotypic slice culture model demonstrates inter-neuronal spreading of alpha-synuclein aggregates

Here we describe the use of an organotypic hippocampal slice model for studying α-synuclein aggregation and inter-neuronal spreading initiated by microinjection of pre-formed α-synuclein fibrils (PFFs). PFF in...

Authors:Sara Elfarrash, Nanna Møller Jensen, Nelson Ferreira, Cristine Betzer, Jervis Vermal Thevathasan, Robin Diekmann, Mohamed Adel, Nisreen Mansour Omar, Mohamed Z. Boraie, Sabry Gad, Jonas Ries, Deniz Kirik, Sadegh Nabavi and Poul Henning Jensen

Citation:Acta Neuropathologica Communications 2019 7:213

Content type:Methodology article

Published on: 19 December 2019

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