CIENCIASMEDICASNEWS: Medical News | Medical Articles: When HPLC fails: Unleashing the Potential of IC

jueves, 26 de septiembre de 2019

Medical News | Medical Articles: When HPLC fails: Unleashing the Potential of IC

	September 26, 2019
	Analytical Chromatography
	The latest chromatography news from NewsMedical

When HPLC fails: Unleashing the Potential of IC

Have you ever tried measuring ionic analytes or organic acids with High-Performance Liquid Chromatography (HPLC)? Good luck with that! Ion Chromatography can separate multiple ions and detect them using a conductivity detector. And because chemical suppression lowers background conductivity, sensitivity is not an issue, making IC suitable for trace- and ultratrace-level measurements.

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			Metabolomic Profiling of an Ancient Herbal Medicine using UHPLC Herbal medicines have been used for centuries in Asian countries, yet many of the active ingredients of such therapies remain unknown. Now, researchers from Argentina and Chile have carried out an assessment of the in vitro medicinal effects of the South American 'quilchamalí plant', or Baccharis grisebachii.

			Using anion exchange chromatography and electrochemical detection for determination of carbohydrates Carbohydrates are among the most widespread organic compounds in the living nature. As monosaccharides and di-saccharides, they primarily serve the direct supply of energy in the organism. In the form of oligomers or polymers, they are used more for storage of energy or information, or take over tasks as a structural element in cell walls, primarily of plants.

	Identifying Protein Biomarkers for COPD from Exhaled Air Condensate Chronic obstructive pulmonary disease (COPD) is a medical condition where damage to the airway leads to a chronic inflammatory response. In this case study, scientists from Peking and Shanghai identified novel protein biomarkers from exhaled air condensate provided by patients with COPD.

	Combating Counterfeit Green Tea with Metabolomic Profiling Green tea is a popular beverage that has traditionally been produced in several Asian countries. The origin of green tea is a key market factor for consumers, and this has led to a surge in counterfeit tea products. Thus, methods that can be used to authenticate green tea are in high demand.

	A Computational Tool for Column Selection in 2D Chromatography Two-dimensional (2D) liquid chromatography is a powerful tool to separate complex compound mixtures. The principle behind 2D liquid chromatography is that compounds in a sample are separated by two subsequent chromatography steps, which separate the compounds based on different physicochemical parameters.

	Aqueous Two-phase Systems: Pros and Cons Phase systems consisting of polymers or polymers with saltwater can be used to separate cells, membranes, viruses, proteins and other biomolecules. Aqueous two-phase systems, also known as ATPS, use the properties of the polymer surface and conformation of the materials to partition biomolecules.