Understanding the Chromosomal Abnormality known as Uniparental Disomy

Uniparental disomy occurs when cells contain two copies of a chromosome from one parent and none from the other parent. Inappropriate gene activity disrupts chromosome segregation and generates uniparental disomy, present in many cancer cells.
ccr.cancer.gov/Laboratory-of-Biochemistry-and-Molecular-Biology
ccr.cancer.gov/Laboratory-of-Biochemistry-and-Molecular-Biology/shiv-grewal
ccr.cancer.gov/Laboratory-of-Biochemistry-and-Molecular-Biology/h-diego-folco