CIENCIASMEDICASNEWS: Studying Cellular Metabolism with Label-Free 3D Live Imaging of Cells

viernes, 19 de octubre de 2018

Studying Cellular Metabolism with Label-Free 3D Live Imaging of Cells

	October 19, 2018
	Metabolomics
	The latest metabolomics news from AZoNetwork

Studying Cellular Metabolism with Label-Free 3D Live Imaging of Cells

Cellular metabolism is a complex process with intricately interwoven components in the thousands. It is kept going by many important cell organelles such as lipid droplets and mitochondria, which take part in numerous cell processes involving energy and cell signaling pathways.

			How are the Metabolome and Proteome Related? As the proteome consists of proteins and metabolome consists of an eclectic mix of molecules, ranging from amino acids to carbohydrates, it is easy to forget that these two groups are intimately connected.

			Metabolomics in Pharmacology Metabolomics is the holistic study of metabolism. The application of metabolomics in pharmacology gives rise to a new field called “pharmacometabolomics.” The basic tenet of pharmacometabolomics is to determine the effects of drug treatment on the body’s metabolic scenario. It is also used to identify specific metabolic pathways that are responsible for drug-mediated outcomes.

	Researchers make discovery about yeast metabolism that could help drug developers Researchers at the Francis Crick Institute have developed machine learning algorithms that can predict the metabolism of yeast based on its protein content.

	Metabolic signatures in blood may help in earlier diagnosis of autism, shows research Metabolic signatures in the blood of children with autism spectrum disorder may lead to earlier diagnosis of the condition for some children, according to newly published research. These biochemical signatures provide insight into how the body metabolizes certain amino acids important to typical neurodevelopment.

	Targeted Metabolomics Metabolome can be described as the terminal output of the genome that comprises the overall complement of metabolites (molecules with low molecular weight) in an organism or cell. The technique of measuring molecules is divided into two groups: targeted metabolomics and untargeted metabolomics.

	Microbial Dysbiosis and Colorectal Cancer The commensal bacteria in the human gut helps to maintain homeostasis and contribute to the health of their host. These microorganisms exist in a careful balance and, if disrupted, this can contribute to the development of disease.

	Metabolome tests could be new way to measure obesity and health The link between obesity and health problems may seem apparent. People who are obese are at higher risk of type 2 diabetes, liver disease, cancer, and heart disease.

	Metabolomic Analysis of Chilli Peppers This article describes a study using Bruker instrumentation for metabolomic analysis of chilli peppers.