Incidence of myeloproliferative neoplasms in Calgary, Alberta, Canada

Jonathan Heppner,
Leonard Tu Nguyen,
Maggie Guo,
Christopher Naugler and
Fariborz Rashid-KolvearEmail author

BMC Research Notes201912:286

https://doi.org/10.1186/s13104-019-4321-1

Received: 18 January 2019
Accepted: 18 May 2019
Published: 24 May 2019

Abstract

Objective

The incidence of the combined myeloproliferative neoplasms (MPNs) was determined for a major Canadian city. Retrospective cases of MPN diagnoses (essential thrombocythemia, polycythemia vera, and primary myelofibrosis) between 2011 to 2015 were retrieved from the Southern Alberta Cancer Cytogenetics Laboratory’s database at Alberta Public Laboratories.

Results

An incidence rate of 2.05 cases per 100,000 person-years (95% CI 1.73–2.41) was determined, giving an age-standardized Canadian incidence of 2.71 cases per 100,000 person years (95% CI 2.63–2.78). MPN diagnoses occurred at a wide age range of 8–93 (median 66) and an age-dependent increase in incidence. Incidence rates for the MPNs are first reported here for a Canadian population.