CIENCIASMEDICASNEWS: Pursuing Disease Causation for the Creation Of Microbiome Based Therapeutics

jueves, 4 de abril de 2019

Pursuing Disease Causation for the Creation Of Microbiome Based Therapeutics

	April 4, 2019
	Microbiology
	The latest microbiology news from AZoNetwork

Pursuing Disease Causation for the Creation Of Microbiome Based Therapeutics
Join the 4th Microbiome Movement - Drug Development Summit (Boston, June 26-28) to help discover, develop and deliver the next generation of microbiome-based therapeutic and diagnostic candidates to market. Set to tackle the greatest scientific, regulatory, clinical, manufacturing and commercialisation challenges across the entire drug development value chain, this meeting will showcase leading industry case studies focused on enhancing the application of novel technologies to standardise results, accelerate target discovery and optimize the translation of microbiome research into safe and effective therapeutic products. Save 10% with discount code 10009NMLS.

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			British Pioneers in Microbiology Humans have been studying microorganisms for hundreds of years. The first compound microscope was invented by the Janssen brothers (Johannes and Zacharias) in 1590, and formed the basis for the many discoveries that followed.

			New Strategy Employs Engineered Microbe to Turn Lignin into More Valuable Commodity With a few genetic modifications, a type of soil bacteria which feeds on hydrocarbons shows potential as a biological factory for turning a renewable—but disappointingly untapped—reward into a replacement for omnipresent plastics.

	Fish slime could be a potential source of antibiotics finds study With the advent of multi-drug resistant bacteria and lack of new antibiotics, researchers have been on the lookout for new molecules that can fight these pathogens. A team of researchers have now identified a slimy mucous coating of young fish as a potential source for antibiotics that could fight resistant infections such as MRSA (Methicillin Resistant Staphylococcus aureus).

	New study examines presence of microbes in tap water from residences, office buildings Water is a source of concern for disseminating the bacteria Legionella pneumophila and Mycobacterium avium, which cause lung disease (legionellosis and pulmonary nontuberculous mycobacterium disease, respectively).

	Human microbiome metabolites enhance colon injury by enterohemorrhagic E. coli, study shows It remains mysterious why humans get infected by some bacterial or viral pathogens relatively easily while animals that have very similar tissues and immune functions do not. This chasm also is the reason why researchers frequently face problems in their efforts to model pathogenic diseases in animal models, such as mice, and why drugs developed using this approach often fail in humans.

	Research opens up opportunities to unravel the complexity of microbial communities "Microbial communities run the world," says Jo Handelsman, director of the Wisconsin Institute for Discovery at the University of Wisconsin-Madison. "People always laugh when I say that," she adds. "But it's true." Our rich new understanding of microbial communities and their influence on human health or crop productivity has led to the dream of changing these communities to produce benefits. In pursuit of that dream, millions of Americans now take probiotics, beneficial microbes they hope will improve their gut.