Cells on the lookout.
Meningeal macrophages (shown in white, red, and blue) are on constant alert against potential threats to brain tissue. Image courtesy of the McGavern Lab, NINDS.
Meningeal macrophages (shown in white, red, and blue) are on constant alert against potential threats to brain tissue. Image courtesy of the McGavern Lab, NINDS.
Meningitis changes immune cell makeup in the mouse brain lining
Monday, March 18, 2019
NIH study finds new cell composition may lead to less effective future response
Meningitis, a group of serious diseases which infect the brain’s lining, leaves its mark and can affect the body’s ability to fight such infections in the future. According to a new study published in Nature Immunology, infections can have long-lasting effects on a population of meningeal immune cells, replacing them with cells from outside the meninges that then change and become less likely to recognize and ward off future attacks. The research was supported by the National Institute of Neurological Disorders and Stroke (NINDS), part of the National Institutes of Health.
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