lunes, 5 de noviembre de 2018

Coeliac Disease Symptoms

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By Ananya Mandal, MDReviewed by April Cashin-Garbutt, MA (Cantab)

Celiac disease affects the small intestines and the symptoms are usually brought about by the ingestion of gluten.

The presentation of celiac disease may be varied with a wide range of severity of the symptoms. This makes diagnosis a challenge based on symptoms alone. Research suggests that diagnosis usually takes around 10 years after the appearance of first symptoms.

For example, reports suggest that celiac disease may be detected in adults presenting with iron-deficiency anaemia and in adults presenting with low bone-mineral density.

The prevalence of celiac disease in people with iron-deficiency anaemia ranges from 2.3 to 15% and the prevalence of celiac disease in people with low bone mineral density ranges from 0 to 3%.

General symptoms of celiac disease

Broadly found the symptoms and signs of celiac disease include:–

Iron-deficiency anaemia and other or unspecified anaemia
Anorexia
Weight loss
Abdominal distension/bloating
Abdominal pain
Flatulence
Vomiting
Diarrhoea
Constipation and irregular bowel habits
Short stature/growth failure and failure to thrive
Irritability, mood swings and depression/bipolar disorder
Alopecia
Osteoporosis
Recurrent aphthous stomatitis
Amenorrhoea/recurrent abortion and infertility
Hypertransaminaseaemia and abnormal liver biochemistry

Associated features and diseases

There are several associated features and diseases as well. These include:-

Dermatitis herpetiformis
Irritable bowel syndrome
Liver disorders
Microscopic colitis
Rheumatological disorders including Rheumatoid arthritis
Crohn’s disease and Inflammatory bowel disease
Type 1 diabetes – the prevalence of celiac disease in people with type 1 diabetes is 1.4 to 8.2% in children, 0.3 to 11.3% in adults and 1.7 to 5.7% in combined child and adult populations.
Autoimmune thyroid disease
Down syndrome
Epilepsy
Infertility
Lymphoid malignancy
Autoimmune Myocarditis
Sjögren's syndrome
Sarcoidosis
Turner syndrome
Chronic thrombocytopenic purpura
Polyneuropathy