martes, 31 de mayo de 2016

Wilms Tumor and Other Childhood Kidney Tumors Treatment (PDQ®)—Health Professional Version - National Cancer Institute

Wilms Tumor and Other Childhood Kidney Tumors Treatment (PDQ®)—Health Professional Version - National Cancer Institute





National Cancer Institute

Wilms Tumor and Other Childhood Kidney Tumors Treatment (PDQ®)–Health Professional Version

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Changes to This Summary (05/27/2016)

The PDQ cancer information summaries are reviewed regularly and updated as new information becomes available. This section describes the latest changes made to this summary as of the date above.
Added text to state that when 519 Wilms tumors were screened for RESTmutations, 9 were found, and most were also present in the germline, sometimes with parents also positive for the mutation, strongly suggesting that it is a Wilms tumor predisposition gene, whether inherited from a parent or as a new mutation.
Revised text to state that no other recurrent segmental chromosomal copy number changes or somatic variants were identified, providing further support for the role of BCOR internal tandem duplication as the primary oncogenic driver for clear cell sarcoma of the kidney.
This summary is written and maintained by the PDQ Pediatric Treatment Editorial Board, which is editorially independent of NCI. The summary reflects an independent review of the literature and does not represent a policy statement of NCI or NIH. More information about summary policies and the role of the PDQ Editorial Boards in maintaining the PDQ summaries can be found on the About This PDQ Summary and PDQ® - NCI's Comprehensive Cancer Database pages.
  • Updated: May 27, 2016

1 comentario:

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