
New Funding Initiatives on “Phased Innovation Award for Mechanistic Studies to Optimize Mind and Body Interventions”
Wen G. Chen, Ph.D.
NCCIH has recently published two Requests for Applications (RFAs):
You may wonder why it’s important to study the mechanisms or biological processes by which mind and body interventions work. Isn’t it enough to figure out if they work or not? A major challenge for mind and body interventions has been the relative lack of compelling efficacy and effectiveness evidence for specific medical conditions. For those interventions for which we have anecdotal or sporadic information, the effects are typically small or modest at best. Often, we have difficulty in determining if the interventions are substantially better than placebo effects.
In addition, it is particularly challenging to study the effects of mind and body interventions on chronic medical conditions due to their complexity. For example, most mind and body interventions not only engage multiple components of the nervous systems, such as the brain, spinal cord, or peripheral nerves, but also can impact the associated musculoskeletal system, internal organs, or vascular and endocrine systems directly through nerve regulations by somatosensory, motor, vagus, cranial, or other autonomic nervous systems, or indirectly through the circulation of blood.
Read the full blog and comment>>>
Interested in submitting applications for these RFAs? Register for a Pre-Application Webinar on Wednesday, October 28, at 2 p.m. ET. >>>
- Phased Innovation Award for Mechanistic Studies to Optimize Mind and Body Interventions in NCCIH High Priority Research Topics (R61/R33)
- Innovation Award for Mechanistic Studies to Optimize Mind and Body Interventions in NCCIH High Priority Research Topics (R33)
You may wonder why it’s important to study the mechanisms or biological processes by which mind and body interventions work. Isn’t it enough to figure out if they work or not? A major challenge for mind and body interventions has been the relative lack of compelling efficacy and effectiveness evidence for specific medical conditions. For those interventions for which we have anecdotal or sporadic information, the effects are typically small or modest at best. Often, we have difficulty in determining if the interventions are substantially better than placebo effects.
In addition, it is particularly challenging to study the effects of mind and body interventions on chronic medical conditions due to their complexity. For example, most mind and body interventions not only engage multiple components of the nervous systems, such as the brain, spinal cord, or peripheral nerves, but also can impact the associated musculoskeletal system, internal organs, or vascular and endocrine systems directly through nerve regulations by somatosensory, motor, vagus, cranial, or other autonomic nervous systems, or indirectly through the circulation of blood.
Read the full blog and comment>>>
Interested in submitting applications for these RFAs? Register for a Pre-Application Webinar on Wednesday, October 28, at 2 p.m. ET. >>>


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