Beyond the Genome: Advances in Epigenomics - February 18, 2015

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Epigenetics

Beyond the Genome: Advances in Epigenomics - February 18, 2015

Beyond the genome
Nature Editorial, February 18, 2015
Studies of the epigenomic signatures of many healthy and diseased human tissues could provide crucial information to link genetic variation and disease.

Presenting the Epigenome Roadmap
Nature 518, 313 (19 February 2015)

Welcome to the Epigenome Roadmap
Nature, February 2015

Epigenomics: Roadmap for regulation
C Romanoski et al. Nature 518, 314?316 (19 February 2015)

Interpreting variation: GWAS, cancer, genotype, evolution and allelic
Nature 18 February 2015

Epigenomic annotation of genetic variants using the Roadmap Epigenome Browser
X Zhou et al. Nature Biotechnology, February 2015

Scientists just made the first map of the human epigenome. Here's why that's awesome, by Rachel Feltman, the Washington Post, Feb 18

Huge epigenomic map examines life's impact on our genes, by Catherine Brahic, New Scientist, Feb 18

Epigenome: The symphony in your cells, Nature Podcast Video, February 2015

The Epigenetic Clock and Health: Hope and Hype - February 9, 2015

DNA methylation age of blood predicts all-cause mortality in later life. 
Riccardo E Marioni et al. Genome Biology, January 30, 2015

DNA methylation predicts death, by Kristie Nybo, Biotechniques, Feb 3

Newly discovered DNA clock runs too fast - scientific evidence can hardly keep up, by Cecile Janssens, Huffington Post, Feb 5

Google Calendar gives count-down remaining life expectancy based on DNA methylation, by Cecile Janssens , Blog Post, Jan 31

How does the body know how old it is? Introducing the epigenetic clock hypothesis.
Mitteldorf J. Interdiscip Top Gerontol. 2015;40:49-62.

Biomarkers and ageing: The clock-watcher.
Gibbs WW. Nature. 2014 Apr 10;508(7495):168-70

The epigenetic clock is correlated with physical and cognitive fitness in the Lothian Birth Cohort 1936.
Marioni RE, et al. Int J Epidemiol. 2015 Jan 22

Circadian clocks, epigenetics, and cancer.
Masri S, et al. Curr Opin Oncol. 2015 Jan;27(1):50-

DNA methylation age of human tissues and cell types.
Horvath S. Genome Biol. 2013;14(10):R115.

Is your DNA Clock running fast? You may die sooner than later, GEN News Highlights, Feb 2

Epigenetics: Linking the Environment to Human Disease - October 9, 2014

New CDC blog post: Epigenetics and public health: Why we should pay attention

Epigenetics/inheritance and the environment. The genome's dynamic response to the environment,Educational resources from the National Library of Medicine

Diverse epigenetic mechanisms of human disease. 
Brookes E, Shi Y. Annu Rev Genet. 2014 Sep 5.

Epigenome: Biosensor of cumulative exposure to chemical and nonchemical stressors related to environmental justice. 
Kenneth Olden, et al. Am Journal Public Health, October 2014

Epigenetics: relevance and implications for public health. 
Rozek LS, et al. Annu Rev Public Health. 2014;35:105-22

Epigenetics across the human lifespan
Antonei B. Csoka et al.  Front. Cell Dev. Biol. August 2014

Epigenetics. Looking beyond our DNA. Horizons in bioscience.  [PDF 10.63 MB] 
The Federation of American Societies for Experimental Biology (FASEB) (2014)

Do early paternal exposures to lifestyle factors such as smoking increase the risk of chronic diseases in the offspring?
Adelheid Soubry et al. European Journal Human Genetics, October 8, 2014

High-resolution digital profiling of the epigenome.
Gabriel E. Zentner et al. Nature Reviews Genetics, 09 October 2014

Fast facts about epigenetics,  [PDF 537.22 KB] from the University of Washington in Seattle