Schizophrenia (SZ) is a complex polygenic psychiatric disorder caused in part by abnormal dopamine levels. Cerebral dopamine neurotrophic factor (CDNF) 2 is known to protect and repair the dopaminergic system. Do...
Olfaction is often affected in parkinsonian patients, but dopaminergic cells in the olfactory bulb are not affected by some Parkinson-inducing drugs. We investigated whether the drug MPTP produces the olfactor...
Attention deficit hyperactivity disorder (ADHD) is a prevalent and multifactorial neuropsychiatric disorder in the human population worldwide. Complex etiology and clinical heterogeneity have challenged the re...
Authors:Jenni Puurunen, Sini Sulkama, Katriina Tiira, Cesar Araujo, Marko Lehtonen, Kati Hanhineva and Hannes Lohi
Citation:Behavioral and Brain Functions 2016 12:27
To reduce the number of patients with depression, biomarkers for clarifying psychiatric disorders are warranted. Numerous candidates have been proposed; however, near-infrared spectroscopy (NIRS) with multi-ch...
Authors:Shinya Kinoshita, Tetsufumi Kanazawa, Hiroki Kikuyama and Hiroshi Yoneda
Citation:Behavioral and Brain Functions 2016 12:25
We investigated whether variation in the dopamine D2 receptor gene (DRD2) and tri-dimensional personality questionnaire (TPQ) scores could be used to aid adjustment of daily methadone requirements of heroin addic...
Authors:Min-Wei Huang, Tai-An Chiang, Pei-Yu Lo and Ching-Shan Huang
Citation:Behavioral and Brain Functions 2016 12:24
Cancer diagnosis is associated with an increased suicide risk, particularly within the first 1 year after diagnosis of cancer. Abnormal function of the hypothalamic–pituitary–adrenal axis has been implicated i...
Authors:Subin Park, Jin Pyo Hong, Jong-Keuk Lee, Young-Mi Park, Yangsoon Park, Juri Jeon, Myeong Hee Ahn and Se Chang Yoon
Citation:Behavioral and Brain Functions 2016 12:22
As the prevalence of autism spectrum disorders in people with epilepsy ranges from 15 to 47 % (Clarke et al. in Epilepsia 46:1970–1977, 2005), it is speculated that there is a special relationship between the two...
Authors:Chanyoung Ko, Namwook Kim, Eunjoo Kim, Dong Ho Song and Keun-Ah Cheon
Citation:Behavioral and Brain Functions 2016 12:20
Whereas acute nicotine administration alters brain function which may, in turn, contribute to enhanced attention and performance, chronic cigarette smoking is linked with regional brain atrophy and poorer cogn...
Authors:Matthew T. Sutherland, Michael C. Riedel, Jessica S. Flannery, Julio A. Yanes, Peter T. Fox, Elliot A. Stein and Angela R. Laird
Citation:Behavioral and Brain Functions 2016 12:16
Potassium bromate (KBrO3) is widely used as a food additive and is a major water disinfection by-product. The present study reports the side effects of KBrO3 administration on the brain functions and behaviour of...
Authors:Jamaan Ajarem, Naif G. Altoom, Ahmed A. Allam, Saleh N. Maodaa, Mostafa A. Abdel- Maksoud and Billy KC. Chow
Citation:Behavioral and Brain Functions 2016 12:14
Anxieties, such as shyness, noise phobia and separation anxiety, are common but poorly understood behavioural problems in domestic dogs, Canis familiaris. Although studies have demonstrated genetic and environmen...
Authors:Jenni Puurunen, Katriina Tiira, Marko Lehtonen, Kati Hanhineva and Hannes Lohi
Autism spectrum disorder (ASD) refers to a broad spectrum of neurodevelopmental disorders characterized by three central behavioral symptoms: impaired social interaction, impaired social communication, and res...
Authors:Hyopil Kim, Chae-Seok Lim and Bong-Kiun Kaang
High-mobility group box 1 (HMGB1) was observed to be an important extracellular mediator involved in vascular inflammation associated with subarachnoid hemorrhage (SAH). This study is of interest to examine th...
Authors:Chih-Zen Chang, Shu-Chuan Wu, Aij-Lie Kwan and Chih-Lung Lin
Citation:Behavioral and Brain Functions 2015 11:28
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