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Cancer Cell International

Featured article: miR-422a inhibits cell proliferation in colorectal cancer by targeting AKT1 and MAPK1

miRNAs are regarded as molecular biomarkers and therapeutic targets for colorectal cancer (CRC). However, the function and underlying mechanism of miR-422a in the progression of CRC remain largely unknown. In this study, Wei et al. report that miR-422a is down‑regulated in CRC tissues and cell lines and inhibits cell proliferation in CRC by targeting AKT1 and MAPK1.

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1. PRIMARY RESEARCH

   ROR2 receptor promotes the migration of osteosarcoma cells in response to Wnt5a

   Bin Dai, Ting Yan and Ailiang Zhang

   Published on: 29 November 2017
2. PRIMARY RESEARCH

   RAC3 influences the chemoresistance of colon cancer cells through autophagy and apoptosis inhibition

   María Fernanda Rubio, María Cecilia Lira, Francisco Damián Rosa, Adrían Dario Sambresqui, María Cecilia Salazar Güemes and Mónica Alejandra Costas

   Published on: 28 November 2017
3. REVIEW

   Natural agents mediated autophagic signal networks in cancer

   Eun Jung Sohn and Hwan Tae Park

   Published on: 28 November 2017
4. PRIMARY RESEARCH

   Volatile organic metabolites identify patients with gastric carcinoma, gastric ulcer, or gastritis and control patients

   Hongshuang Tong, Yue Wang, Yue Li, Shujuan Liu, Chunjie Chi, Desheng Liu, Lei Guo, Enyou Li and Changsong Wang

   Published on: 21 November 2017
5. PRIMARY RESEARCH

   Inhibition of breast cancer cell proliferation and tumorigenesis by long non-coding RNA RPPH1 down-regulation of miR-122 expression

   Yi Zhang and Lili Tang

   Published on: 21 November 2017

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