Revised text about a study of 670 survivors of Hodgkin lymphoma who have lived 10 or more years that found myocardial infarction and structural heart defects were the major contributors to the excess grade 3 to grade 5 cumulative burden in survivors.
Added text about dexrazoxane’s association with secondary cancers (cited Chow et al., Tebbi et al., and Walker et al. as references 41, 42, and 43, respectively).
Added text about the results of a study of 3,172 5-year survivors of childhood cancer who received 10 Gy or higher to the Circle of Willis and at age 45 years the cumulative incidence of stroke was 11.3% (cited El-Fayech et al. as reference 51).
Added text to state that the prefrail phenotype is characterized by having two of five characteristics (low muscle mass, self-reported exhaustion, low energy expenditure, slow walking speed, and weakness) and the frail phenotype is characterized by having three or more of these characteristics.
Added text about a Childhood Cancer Survivor Study that compared self-reported pulmonary outcomes and their impact on daily activities among 5-year cancer survivors and a sibling cohort noting that by age 45 years, the cumulative incidence of any pulmonary condition was 29.6% for survivors (cited Dietz et al. as reference 4).
ver historia personal en: www.cerasale.com.ar [dado de baja por la Cancillería Argentina por temas políticos, propio de la censura que rige en nuestro medio]//
weblog.maimonides.edu/farmacia/archives/UM_Informe_Autoevaluacion_FyB.pdf - //
weblog.maimonides.edu/farmacia/archives/0216_Admin_FarmEcon.pdf - //
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