lunes, 30 de octubre de 2017

Major study of genetics of breast cancer provides clues to mechanisms behind the disease | University of Cambridge

Major study of genetics of breast cancer provides clues to mechanisms behind the disease | University of Cambridge

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Seventy-two new genetic variants that contribute to the risk of developing breast cancer have been identified by a major international collaboration involving hundreds of researchers worldwide. 

There are some clear patterns in the genetic variants that should help us understand why some women are predisposed to breast cancer, and which genes and mechanisms are involved
Doug Easton
Of these variants, reported today in the journals Nature and Nature Genetics, 65 are common variants that predispose to breast cancer and a further seven predispose specifically to oestrogen-receptor negative breast cancer – the subset of cases that do not respond to hormonal therapies, such as the drug tamoxifen.

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