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Featured collection: Translation in healthcare

 This article collection emerges from the ‘Translation in Healthcare: Exploring the Impact of Emerging Technologies’ conference 2015 hosted by the Centre for Health, Law and Emerging Technologies (HeLEX) at the University of Oxford. Here a wide range of voices were brought together to discuss and think more deeply about the technological, legal, ethical, and social challenges raised by new technologies in healthcare.

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Featured article: Human genome in the Cloud

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Data on human genomes is becoming more and more available, raising questions about patient privacy and inappropriate data sharing. While it is possible to move genomic data analysis to the cloud maintaining sufficient protection of patient privacy and scalability of the computation, greater efficiency in terms of compute time and memory utilization is needed before these systems are sufficiently practical for real world environments.

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1. RESEARCH ARTICLE

   Genetic study of congenital bile-duct dilatation identifies de novo and inherited variants in functionally related genes

   John K. L. Wong, Desmond Campbell, Ngoc Diem Ngo, Fanny Yeung, Guo Cheng, Clara S. M. Tang, Patrick H. Y. Chung, Ngoc Son Tran, Man-ting So, Stacey S. Cherny, Pak C. Sham, Paul K. Tam and Maria-Mercè Garcia-Barcelo

   Published on: 12 December 2016
2. RESEARCH

   A pilot study on the prevalence of DNA palindromes in breast cancer genomes

   Sandeep Subramanian, Srilakshmi Chaparala, Viji Avali and Madhavi K. Ganapathiraju

   Published on: 5 December 2016
3. RESEARCH

   Rules of co-occurring mutations characterize the antigenic evolution of human influenza A/H3N2, A/H1N1 and B viruses

   Haifen Chen, Xinrui Zhou, Jie Zheng and Chee-Keong Kwoh

   Published on: 5 December 2016
4. RESEARCH

   Epigenetic profiling of human brain differential DNA methylation networks in schizophrenia

   Sheng-An Lee and Kuo-Chuan Huang

   Published on: 5 December 2016
5. RESEARCH

   GSNFS: Gene subnetwork biomarker identification of lung cancer expression data

   Narumol Doungpan, Worrawat Engchuan, Jonathan H. Chan and Asawin Meechai

   Published on: 5 December 2016

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