domingo, 25 de septiembre de 2016

Urologists' Current Practices in Screening and Treating Men with a Family History of Prostate Cancer. - PubMed - NCBI

2016 Sep 16. pii: S0090-4295(16)30460-5. doi: 10.1016/j.urology.2016.07.032. [Epub ahead of print]

Urologists' Current Practices in Screening and Treating Men with a Family History of Prostate Cancer.

Rudichuk L1, Vogel KJ2, Wang CH3, Helfand BT3, Selkirk CG3.

Author information

Abstract

OBJECTIVE:

To assess urologists' knowledge and utilization of family history in order to determine prostate cancer (PC) screening and treatment recommendations.

METHODS:

Questionnaires that explored urologists' knowledge, frequency and utilization of family history information for screening and treatment recommendations for PC was prospectively collected. Data were summarized and compared using descriptive statistics.

RESULTS:

A total of 87 responses were collected, for a response rate of 60% (87/145). The majority of urologists reported that they always collect family history when discussing risk (95%) or screening (87%), and recommended earlier screening for men with family history of PC in comparison to men with no family history. Although only 57% reported always collected family history when discussing treatment, the majority of respondents reported that a positive family history influenced their treatment recommendations. Eight percent of urologists would recommend prostatectomy for men diagnosed with low grade, low risk PC and no family history of PC versus 52% who would recommend the same course of treatment when the patient had at least 1 first degree relative (FDR) who died of the disease. Conversely, 91% of urologists would recommend active surveillance for men with low grade, low risk PC and no family history versus 47% for those with at least 1 FDR who died of the disease.

CONCLUSION:

The majority of urologists collect information on family history of PC. Despite the lack of literature to support that familial PC patients require more aggressive treatment, urologists were more likely to recommend definitive therapies.