Recent Press Releases
- TCGA findings on papillary renal cell carcinoma and prostate cancerNovember 5, 2015Researchers with The Cancer Genome Atlas (TCGA) report new findings on papillary renal cell carcinoma and prostate cancer.
- TCGA study identifies genomic features of invasive lobular breast carcinomaOctober 8, 2015Investigators with The Cancer Genome Atlas (TCGA) Research Network have identified molecular characteristics of a type of breast cancer, invasive lobular carcinoma (ILC), that distinguishes it from invasive ductal carcinoma (IDC), the most common invasive breast cancer subtype.
- Cellular factors that shape the 3D landscape of the genome identifiedAugust 13, 2015Researchers, using novel large-scale imaging technology, have mapped the spatial location of individual genes in the nucleus of human cells and identified 50 cellular factors required for the proper 3D positioning of genes. These spatial locations play important roles in gene expression, DNA repair, genome stability, and other cellular activities.
- Study shows promise of precision medicine for most common type of lymphomaJuly 20, 2015A clinical trial has shown that patients with a specific molecular subtype of diffuse large B-cell lymphoma are more likely to respond to the drug ibrutinib than patients with another molecular subtype of the disease
- Changing patterns in survival for U.S. women with invasive breast cancerJuly 20, 2015Large-scale study helps clarify factors associated with breast cancer survival in women of all ages.
- TCGA study improves understanding of genetic drivers of cutaneous melanomaJune 18, 2015A comprehensive analysis of the genome of cutaneous melanoma has provided new insights into the roles of frequently mutated cancer genes and other genomic alterations that drive the development of this disease.
- Genomic underpinnings of brain tumors expandedJune 10, 2015TCGA researchers analyzed nearly 300 cases of diffuse low- and intermediate-grade gliomas, which together comprise lower-grade gliomas. LGGs occur mainly in adults and include astrocytomas, oligodendrogliomas and oligoastrocytomas.
- Benefit of fewer than three doses of HPV vaccine reportedJune 10, 2015Analysis of two independent HPV trials find benefit from fewer than 3 doses of the of the HPV 16/18 AS04-adjuvanted vaccine (Cervarix®).
- NCI-MATCH trial will link targeted cancer drugs to gene abnormalitiesJune 1, 2015Investigators for the nationwide trial, NCI-MATCH: Molecular Analysis for Therapy Choice, announced that the trial will seek to determine whether targeted therapies for people whose tumors have specific gene mutations will be effective regardless of their cancer type. NCI-MATCH will incorporate more than 20 different study drugs or drug combinations, each targeting a specific gene mutation, in order to match each patient in the trial with a therapy that targets a molecular abnormality in their tumor.
- Near-atomic resolution of protein structure by electron microscopy holds promise for drug discoveryMay 7, 2015An imaging technique, cryo-electron microscopy, can view in near-atomic detail the architecture of an enzyme bound to a drug that blocks its activity.
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