ARRS: CT-guided irreversible electroporation safe in unresectable pancreatic carcinoma
as presented at the annual meeting of the American Roentgen Ray Society
A small group of patients with locally advanced unresectable pancreatic carcinoma suffered no major ill effects -- pancreatitis or fistula formation -- after undergoing percutaneous CT-guided irreversible electroporation (IRE), a nonthermal ablation technology that is safe near vascular and ductal structures, as therapy. The study describing the technique was presented at ARRS, held in May in San Diego.
“Our findings exceeded our expectations,” said Maria Paola Belfiore, a researcher at the Institute of Radiology, Second University of Naples. “In fact, three patients were downstaged, and so had a greater life expectancy. This is a great new promise for inoperable pancreatic tumors.”
The ablation procedure was successful in 100% of the patients. These early results represent a good alternative to intraoperative IRE ablation, the researchers said, and offer a safe and feasible primary local treatment for locally advanced pancreatic cancer.
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