Genetics of Kidney Cancer (Renal Cell Cancer) (PDQ®)–Health Professional Version

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Changes to This Summary (06/30/2016)

The PDQ cancer information summaries are reviewed regularly and updated as new information becomes available. This section describes the latest changes made to this summary as of the date above.

Introduction

Added text to state that in a study of 80,309 monozygotic twin individuals and 123,382 same-sex dizygotic twin individuals, the overall heritability of cancer, calculated by assessing the relative contribution of heredity versus shared environment, was estimated to be 33%. Heritability of kidney cancer was estimated to be 38%, with shared environmental factors not showing a significant contribution to overall risk.

This summary is written and maintained by the PDQ Cancer Genetics Editorial Board, which is editorially independent of NCI. The summary reflects an independent review of the literature and does not represent a policy statement of NCI or NIH. More information about summary policies and the role of the PDQ Editorial Boards in maintaining the PDQ summaries can be found on the About This PDQ Summary and PDQ® - NCI's Comprehensive Cancer Database pages.

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Major Heritable Renal Cell Cancer Syndromes

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About This PDQ Summary

Genetics of Kidney Cancer (Renal Cell Cancer) (PDQ®)—Health Professional Version - National Cancer Institute