Human Genomics across the Lifespan ▲ Public Health Genomics Knowledge Base (beta version)

Public Health Genomics Knowledge Base (beta version)

Health Impact Weekly Scan

Human Genomics across the Lifespan

• Birth/Child Health
• Cancer
• Ehics/Policy/Law
• Practice
• Newborn Screening
• Pharmacogenomics
• Reproductive Health
• News/ Reviews/Comments
• Event
• CDC-Authored Genomics Publications

Birth Defects and Child Health

• Clinical utility gene card for: acrodermatitis enteropathica - update 2015. 
  Küry Sébastien, et al. European journal of human genetics : EJHG 2015 10 0.

Cancer

• Patient Perceptions of Telephone vs. In-Person BRCA1/BRCA2 Genetic Counseling. 
  Peshkin Beth N, et al. Journal of genetic counseling 2015 10 0.
• BRCA1 and BRCA2 mutations in Japanese patients with ovarian, fallopian tube, and primary peritoneal cancer. 
  Sakamoto Ikuko, et al. Cancer 2015 10 0.
• Communication Between Breast Cancer Patients Who Received Inconclusive Genetic Test Results and Their Daughters and Sisters Years After Testing. 
  Baars Jessica E, et al. Journal of genetic counseling 2015 10 0.
• Uptake of risk-reducing salpingo-oophorectomy among female BRCA mutation carriers: experience at the National Cancer Center of Korea. 
  Kim Se Ik, et al. Journal of cancer research and clinical oncology 2015 10 0.
• Genetic testing for Lynch syndrome: family communication and motivation. 
  Leenen Celine H M, et al. Familial cancer 2015 10 0.
• Genetic Counselors' Experiences Regarding Communication of Reproductive Risks with Autosomal Recessive Conditions found on Cancer Panels. 
  Mets Sarah, et al. Journal of genetic counseling 2015 10 0.

Ethics, Policy and Law

• FDA's Proposed Guidance for Laboratory Developed Tests: How Should Regulators Balance the Risks and Promise of Innovation in Clinical Genetics?
  Bayefsky Michelle, et al. FDLI's food and drug policy forum 2015 3 0. (2)

Genomics in Practice

• Your DNA is not your diagnosis: getting diagnoses right following secondary genomic findings. 
  Murray Michael F, et al. Genetics in medicine : official journal of the American College of Medical Genetics 2015 10 0.
• CRCDA-Comprehensive resources for cancer NGS data analysis. 
  Thangam Manonanthini, et al. Database : the journal of biological databases and curation 2015 0 0.
• Overview of 'Omics Technologies for Military Occupational Health Surveillance and Medicine. 
  Bradburne Christopher, et al. Military medicine 2015 10 0. (10 Suppl) 34-48
• Developing an intervention to facilitate family communication about inherited genetic conditions, and training genetic counsellors in its delivery. 
  , et al. European journal of human genetics : EJHG 2015 10 0.
• Million Veteran Program (MVP): A Mega-Biobank to Study Genetic Influences On Health and Disease. 
  Gaziano John Michael, et al. Journal of clinical epidemiology 2015 10 0.
• Components of genetic counsellor education: A systematic review of the peer-reviewed literature. 
  Ingvoldstad C, et al. Journal of community genetics 2015 10 0.

Newborn Screening

• Review of Current International Decision-Making Processes for Newborn Screening: Lessons for Australia. 
  Metternick-Jones Selina Carolyne, et al. Frontiers in public health 2015 0 0. 214
• The Newborn Screening Paradox: Sensitivity vs. Overdiagnosis in VLCAD Deficiency. 
  Diekman Eugene, et al. JIMD reports 2015 10 0.

Reproductive Health

• Premarital genetic screening for beta thalassemia carrier status of indexed families using HbA2 electrophoresis. 
  Nosheen Aneeqa, et al. JPMA. The Journal of the Pakistan Medical Association 2015 10 0. (10) 1047-9
• Committee Opinion No. 643: Identification and Referral of Maternal Genetic Conditions in Pregnancy. 
  Obstetrics and gynecology 2015 10 0. (4) e49-51
• Contingent non-invasive prenatal testing: An opportunity to improve non-genetic aspects of fetal aneuploidy screening. 
  Gyselaers Wilfried, et al. Prenatal diagnosis 2015 10 0.

Pharmacogenomics

• A Naturalistic Study of the Effectiveness of Pharmacogenetic Testing to Guide Treatment in Psychiatric Patients With Mood and Anxiety Disorders.
  Brennan Francis X, et al. The primary care companion for CNS disorders 2015 0 0. (2)

News/Reviews/Commentaries

• Estonia wants to collect the DNA of all its citizens, 
  by Katharine Schwab, the Atlantic, October 8, 2015
• Human Longevity, Inc. launches the health nucleus, a comprehensive and personalized health platform for individuals, 
  Human Longevity, October 13, 2015
• The rise of DIY genetic testing, 
  by Emily Matchar, Smithsonian.com, October 13, 2015
• Scientists hope to attract millions to 'DNA.LAND', 
  by Erika Check Hayden, Nature News, October 9, 2015
• Human genetics: Strength in numbers in the low-frequency spectrum. 
  Skipper Magdalena Nature reviews. Genetics 2015 10 0. .
• Epigenetic study of histone modifications and DNA damage could lead to new cancer treatments, 
  by Bailey Kirkpatrick, What is Epigenetics, October 13, 2015
• Gene therapy staves off blindness from retinitis pigmentosa in canine model, 
  NIH News, October 13, 2015
• CDC enters into research collaboration with Edico Genome to evaluate performance of DRAGEN hardware platform, 
  PR Newswire, October 9, 2015
• The tantalizing links between gut microbes and the brain, 
  by Peter Andrey Smith, Nature News, October 14, 2015
• Study shows BRCA mutation screening needed despite family history, 
  by Leah Lawrence, Cancer Network, October 13, 2015
• UT Southwestern investigators develop new strategy to classify cancers caused by KRAS mutations, 
  News- Medical.net, October 8, 2015
• FDA approves the first disease screening by gene testing company, 
  by Charles Margulis, World Tech Today, October 8, 2015
• Sharing genomic data in the precision medicine era, 
  by Scott Edmunds, Giga Blogs, October 9, 2015
• National Academies Human Gene-Editing Initiative holds public meeting, 
  by Chloe Poston, Genes to Genomes, October 6, 2015
• What You Need to Know About Genetic Counseling, 
  by Georgia Hurst, the Cure, October 8, 2015
• Diagnostic developers target antibiotic resistance, 
  by Viviane Callier, Nature News, October 9, 2015
• 5 major breast cancer advancements you need to know about, 
  by Anna Almendrala, Huffington Post, October 7, 2015
• Precision medicine: what it is and how it will be achieved? 
  Genomics Education Programme, October 12, 2015

All News

Events

• Genomics and Evolution of Pathogens and Hosts 
  November 9-21, 2015 ~ Atlanta, GA

CDC-Authored Genomics Publications

• Structural and Functional Characterization of an Ancient Bacterial Transglutaminase Sheds Light on the Minimal Requirements for Protein Cross-Linking. 
  Fernandes Catarina G, Plácido Diana, Lousa Diana, Brito José A, Isidro Anabela, Soares Cláudio M, Pohl Jan, Carrondo Maria A, Archer Margarida, Henriques Adriano O Biochemistry 2015 9 0. (37) 5723-34.
• Identification of population at risk for future Clostridium difficile infection following hospital discharge to be targeted for vaccine trials. 
  Baggs James, Yousey-Hindes Kim, Ashley Elizabeth Dodds, Meek James, Dumyati Ghinwa, Cohen Jessica, Wise Matt, Clifford McDonald L, Lessa Fernanda C Vaccine 2015 10 0. .
• The Dynamics of Genetic Interactions Between Vibrio metoecus and Vibrio cholerae, Two Close Relatives Co-Occurring in the Environment. 
  Orata Fabini D, Kirchberger Paul C, Méheust Raphaël, Barlow E Jed, Tarr Cheryl L, Boucher Yan Genome biology and evolution 2015 10 0. .