Full-Genome Analysis of Avian Influenza A(H5N1) Virus from a Human, North America, 2013.

Pabbaraju K, Tellier R, Wong S, Li Y, Bastien N, Tang JW, Drews SJ, Jang Y, Davis CT, Fonseca K, Tipples GA.

Abstract

Full-genome analysis was conducted on the first isolate of a highly pathogenic avian influenza A(H5N1) virus from a human in North America. The virus has a hemagglutinin gene of clade 2.3.2.1c and is a reassortant with an H9N2 subtype lineage polymerase basic 2 gene. No mutations conferring resistance to adamantanes or neuraminidase inhibitors were found.

KEYWORDS:

Canada, H5N1 subtype, H9N2 subtype, HPAI, North America, avian influenza, full genome, genome analysis, highly pathogenic avian influenza, human, influenza, influenza A, reassortant, viruses