Asthma Awareness Month: Family History & Genomics

Genomics|Update|Current

Asthma Awareness Month: Family History & Genomics

CDC information: In most cases, we don't know what causes asthma, and we don't know how to cure it. Certain factors may make it more likely for one person to have asthma than another. If someone in your family has asthma, you are more likely to have it 

CDC information: Asthma basics, statistics and surveillance, interventions and resources

A genome-wide association study identifies CDHR3 as a susceptibility locus for early childhood asthma with severe exacerbations.
Klaus Bønnelykke et al. Nature Genetics (2013)

Introduction to genetics and genomics in asthma.
Mathias RA. Adv Exp Med Biol. 2014;795:125-55.

Did you know? More than 1000 genes and 90 genomewide association studies have been reported in relation to asthma risk and outcomes? To find out more, visit the HuGE Navigator

Find out about genetic conditions and tests that have been reported in relation to asthma.Visit the NIH Genetic Testing Registry

CDC paper: Genetic variants in the major histocompatibility complex class I and class II genes are associated with diisocyanate-induced asthma
Yucesoy B,  J Occup Environ Med. 2014 Apr;56(4):382-7