A Pilot Study of Hereditary Breast and Ovarian Kno... [Genet Test Mol Biomarkers. 2009] - PubMed result

Genet Test Mol Biomarkers. 2009 Nov 23. [Epub ahead of print]

A Pilot Study of Hereditary Breast and Ovarian Knowledge Among a Multiethnic Group of Hispanic Women with a Personal or Family History of Cancer.
Vadaparampil ST, Quinn GP, Small BJ, McIntyre J, Loi CA, Closser Z, Gwede CK.

1 Health Outcomes and Behavior Program, Moffitt Cancer Center , Tampa, Florida.

Purpose: To examine knowledge about hereditary breast and ovarian cancer (HBOC) among Mexican, Puerto Rican, and Cuban women. Methods: Women (age range, 18-65 years) with a personal or family history of breast or ovarian cancer were recruited to a mixed methods study using community-based approaches. Fifty-three women participated in the study: 16 Mexicans, 20 Puerto Ricans, and 17 Cubans. The majority of women (64.2%) were born outside the United States. All questions were interviewer administered in Spanish or English. HBOC knowledge was measured using an 11-item instrument developed by the National Center for Human Genome Research. We evaluated whether differences in knowledge varied as a function of Hispanic subethnicity, demographic characteristics, and medical and acculturation characteristics using a series of one-way analysis of variances. Results: The percentage of correct responses on the knowledge instrument ranged from 9.4% to 73.6% (median number of correct responses = 45%). Knowledge did not significantly differ by Hispanic subethnicity (p = 0.51). Exploratory analysis revealed lower knowledge in women with a personal history of cancer (p = 0.03). Conclusion: Our study provides important information about characteristics associated with lower levels of knowledge and specific areas related to HBOC where additional education may be warranted in the Hispanic community.

PMID: 19929403 [PubMed - as supplied by publisher]

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A Pilot Study of Hereditary Breast and Ovarian Kno... [Genet Test Mol Biomarkers. 2009] - PubMed result