TB vaccine from the 1920s shows promise in diabetes trial The shot reduced insulin use for people with type 1 diabetes and another autoimmune condition. By Viviane Callier

https://www.nature.com/articles/d41586-026-01825-w?utm_source=Live+Audience&utm_campaign=be71cea477-nature-briefing-daily-20260610&utm_medium=email&utm_term=0_-33f35e09ea-50432164 A century-old vaccine against tuberculosis helps to regulate blood sugar in people with certain types of diabetes, such that they can reduce their insulin use, according to the results of a phase II clinical trial. The finding adds support for the once-controversial hypothesis that vaccines made with living but weakened pathogens can protect against both their target disease and off-target ones.