NIH researchers identify regulatory cells that shield against inflammatory bowel disease Discovery opens the door for improved diagnoses and treatments.

NIH researchers identify regulatory cells that shield against inflammatory bowel disease Discovery opens the door for improved diagnoses and treatments. Scientists at the National Institutes of Health (NIH) and their colleagues have deciphered a crucial regulatory pathway in the body’s immunologic defense against chronic intestinal inflammation. The research team found that harmful mutations in the GPR15 gene are linked to a cascade of events that cause severe, early-onset inflammatory bowel disease (IBD). The discovery opens new avenues and insights for diagnosing and treating IBD. https://www.nih.gov/news-events/news-releases/nih-researchers-identify-regulatory-cells-shield-against-inflammatory-bowel-disease