https://reference.medscape.com/viewarticle/graduate-student-foot-pain-and-stress-fractures-2026a1000i7k?ecd=WNL_casechlg_260628_MSCPREF_etid8458350&uac=148436CN&impID=8458350
Editor's Note:
The Case Challenge series includes difficult-to-diagnose conditions, some of which are not frequently encountered by most clinicians, but are nonetheless important to accurately recognize. Test your diagnostic and treatment skills using the following patient scenario and corresponding questions. If you have a case that you would like to suggest for a future Case Challenge, please email us at ccsuggestions@medscape.com with the subject line "Case Challenge Suggestion." We look forward to hearing from you.
Hematemesis and Heartburn in a Woman With a History of Heavy NSAID Use
Sarah El-Nakeep, MD
https://reference.medscape.com/viewarticle/hematemesis-and-heartburn-woman-history-heavy-nsaid-use-2026a1000fiv?ecd=WNL_casechlg_260628_MSCPREF_etid8458350&uac=148436CN&impID=8458350
A 50-year-old woman presents with a 1-day history of hematemesis. She reports progressive episodes of vomiting over the preceding month, self-managed with over-the-counter (OTC) antiemetics, as well as severe epigastric pain of increasing intensity. She also reports severe heartburn for the past year, self-treated with milk and OTC antacids.
A 27-Year-Old Model With White Facial Macules and Graying Hair
Miriam Kinai, MBBCh
https://reference.medscape.com/viewarticle/27-year-old-model-white-facial-macules-and-graying-hair-2026a1000d47?ecd=WNL_casechlg_260628_MSCPREF_etid8458350&uac=148436CN&impID=8458350
A Violaceous Retiform Rash With Progressive Lower Extremity Ischemia in a 66-Year-Old Man
Margaret Mercante; Rishab Revankar, MD; Shira Lanyi, MD; Gabrielle Schwartzman, MD; Danielle Nelson, MD; Scott Berg, MD; Barrett Zlotoff, MD
https://reference.medscape.com/viewarticle/violaceous-retiform-rash-progressive-lower-extremity-2026a1000d6p?ecd=WNL_casechlg_260628_MSCPREF_etid8458350&uac=148436CN&impID=8458350
Background, Initial Presentation, and Physical Examination
A 66-year-old man with a history of JAK2-positive essential thrombocytosis, polysubstance use disorder, and prior right lower extremity osteomyelitis status post-toe amputation presents with worsening right foot pain, ulceration, and a violaceous rash extending proximally up the lower extremity. The patient reports having progressive pain and discoloration over several weeks. There is no recent history of trauma, new medications, or systemic infectious symptoms.
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