sábado, 7 de diciembre de 2019

scPopCorn Gets to the Kernel of Single-Cell Experiments: NLM–Made Algorithm Helps NIH Researchers | NLM in Focus

scPopCorn Gets to the Kernel of Single-Cell Experiments: NLM–Made Algorithm Helps NIH Researchers | NLM in Focus

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12/06/2019 11:58 AM EST


Researchers at the National Library of Medicine’s National Center for Biotechnology Information have created a new algorithm called scPopCorn (single-cell subpopulations comparison) to capture the differences among populations of cells from single-cell experiments. The algorithm, developed by my team is available at GitHub and is described in an article in Cell Systems (Y. Wang, J. Honka, and T.M. Przytycka, Cell…
Arrows lead from a tissue sample from a healthy mouse  to multiple cell types (astrocyte, neuron, microglia, OPC, and oligodendrocyte). 
Arrows also lead from a tissue sample of a sick mouse to cell types (cancer, OPC, and oligodendrocyte). 
In the center of the figure, arrows connect both the astrocyte and neuron to the sick mouse's cancer cell suggesting the cancer is the same cell type as the astrocyte and neuron.

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