jueves, 23 de mayo de 2019

Medical News | Medical Articles: Human CD20 Full Length Proteins

Medical News | Medical Articles

 
 May 22, 2019 
 Antibodies 
 The latest antibodies news from News Medical 
 #ALT#Human CD20 Full Length Proteins

CD20 is a hot target for the treatment of lymphoma, leukemia and other autoimmune diseases. However, due to difficulty of expression and unstable bioactivity, it’s difficult to find a suitable CD20 protein for detecting bioactivity of antibody drugs and CD20-CAR expression. ACROBiosystems has recently developed full length multi-transmembrane CD20 proteins, expressed by HEK293 cells and insect cells, respectively with purity and bioactivity verified by SDS-PAGE, ELISA and SPR.

Learn More About Full Length CD20 Proteins
 
 
  KeysightUsing Antibodies to Detect the Expression of Neural Stem Cell Markers
 
Markers against neural stem cells represent a robust tool in basic research and advanced regenerative medicine. Studies focused on differentiation toward specific neural lineages are supported by changes in the expression levels of specific markers, which can help to identify the presence of neural stem cells. 
 
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  KeysightIdentifying Antibodies and Reagents
 
Identify antibodies and reagents for their specific targets, whether their target is one protein, many proteins or other biological molecules. Abcam can also help researchers work on large projects. 
 
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 Neurological Side Effects of CAR T-Cell Therapy Revealed
 
Neurological Side Effects of CAR T-Cell Therapy RevealedResearchers at Brigham and Women’s Hospital quantified the neurological symptoms associated with CAR T-cell therapy and found that 77 percent of patients receiving the treatment experienced at least one neurological side effect.
 
 
 CAR-T Cell Toxicity and Safety Profiles
 
CAR-T Cell Toxicity and Safety ProfilesChimeric antigen receptor T cells are genetically modified to target specific cells; they have been used in research-based cancer treatments. Treatment is associated with numerous side effects and research is being performed on how to reduce them.
 
 
 What are Antinuclear Antibodies?
 
What are Antinuclear Antibodies?Antinuclear antibodies (ANA) are autoantibodies directed against the nuclei of some of one’s own body cells. They are present in the blood in persons with certain autoimmune disorders.
 
 
 Understanding neurotoxic side effects of CAR T-cell therapy
 
Understanding neurotoxic side effects of CAR T-cell therapyThe recent advent of chimeric antigen receptor (CAR) T-cell therapy has revolutionized the clinical treatment of cancer.
 
 
 Naturally occurring human antibody reveals hidden weakness in influenza virus
 
Naturally occurring human antibody reveals hidden weakness in influenza virusThe ever-changing "head" of an influenza virus protein has an unexpected Achilles heel, report scientists funded by the National Institute of Allergy and Infectious Diseases, one of the National Institutes of Health.
 
 
 Slow-release HIV vaccine shows promise in preclinical trials
 
Slow-release HIV vaccine shows promise in preclinical trialsA new slow-release vaccine has been shown to boost the immune system’s response to the HIV virus. The vaccine is given in small doses over a period of days, compared to one large dose.
 
 
 First Footage of T-Cells Training To Fight Pathogens Revealed
 
First Footage of T-Cells Training To Fight Pathogens RevealedImmunologists at The University of Texas at Austin have recorded visuals of T-cells learning what kind of cells to ignore when fighting pathogens, to ensure they do not attack healthy cells and tissues when fighting disease. It is the first time that this process has been captured on video.
 
 
 Insights into parasitic yeast species could lead to new strategies for controlling yeast pathogens
 
Insights into parasitic yeast species could lead to new strategies for controlling yeast pathogensInsights into the genes and proteins involved in the predatory behavior of a parasitic yeast species could lead to new strategies for controlling yeast pathogens, according to a study published May 9 in the open-access journal PLOS Pathogens by Jürgen Wendland of the Carlsberg Research Laboratory in Denmark and Vrije Universiteit Brussel in Belgium, and colleagues.
 
 
 Research reveals sophisticated machinery used by dangerous pathogens to infect hosts
 
Research reveals sophisticated machinery used by dangerous pathogens to infect hostsGastric cancer, Q fever, Legionnaires' disease, whooping cough--though the infectious bacteria that cause these dangerous diseases are each different, they all utilize the same molecular machinery to infect human cells.
 
 
 What Is Waldenström Macroglobulinemia?
 
What Is Waldenström Macroglobulinemia?Waldenström macroglobulinemia (WM) is a form of lymphoma characterized by the presence of large amounts of an antibody called macroglobulin. It is also called lymphoplasmacytic lymphoma. The built up of macroglobulin is responsible for the characteristic symptoms associated with WM.
 
 
 Sophisticated molecular machinery is used by dangerous pathogens to infect hosts
 
Sophisticated molecular machinery is used by dangerous pathogens to infect hostsGastric cancer, Q fever, Legionnaires' disease, whooping cough--though the infectious bacteria that cause these dangerous diseases are each different, they all utilize the same molecular machinery to infect human cells.
 
 
 cGAS–STING Pathway Steps, Regulation, and Oncogenesis
 
cGAS–STING Pathway Steps, Regulation, and OncogenesisThe cGAS–STING pathway is a part of the innate immune system and is involved in the detection of cytosolic deoxyribonucleic acid (DNA).
 
 
 What is Granulomatosis with Polyangiitis?
 
What is Granulomatosis with Polyangiitis?Granulomatosis with polyangiitis (GPA), known as Wegener’s granulomatosis until 2011, is a rare and potentially serious condition that causes inflammation of the small blood vessels and capillaries. It typically affects the ears, nose, sinuses, kidneys, and lungs, and can affect anyone of any age, although it is most commonly seen in middle-aged or elderly people.
 
 
 What is AIDS-Related Lymphoma?
 
What is AIDS-Related Lymphoma?Acquired immunodeficiency syndrome (AIDS) is a state of severe immunosuppression in which patients are at increased risk for lymphoma.
 
 
 Breastfeeding Questions
 
Breastfeeding QuestionsBreastfeeding is one of the most important natural provisions for the baby’s health and development. This process is regulated largely by nervous and hormonal signals.
 
 
 Previous dengue infection could protect against Zika-associated damage
 
Previous dengue infection could protect against Zika-associated damageThe Zika virus outbreak in Latin America has affected over 60 million people up to now. The infection can have potentially fatal consequences for pregnant women and their unborn children: many children have subsequently been born with malformations of the head, or so-called microcephaly.
 
 
 Scientists investigate function of AAPP in mosquito blood feeding
 
Scientists investigate function of AAPP in mosquito blood feedingBiting insects use a range of tools when sucking blood from hosts to maximize their chances of a good meal.
 
 
 NIH announces awards to advance development of vaccines for sexually transmitted infections
 
NIH announces awards to advance development of vaccines for sexually transmitted infectionsThe National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health, today announced awards to establish four Cooperative Research Centers focused on developing vaccines to prevent sexually transmitted infections.
 
 
 UNC and partners receive NIH funding to identify chlamydia vaccine
 
UNC and partners receive NIH funding to identify chlamydia vaccineChlamydia is the most prevalent bacterial sexually transmitted infection (STI) in the world. There is no vaccine to prevent infection. However, researchers from the University of North Carolina at Chapel Hill, in partnership with colleagues at other sites in the US, Europe and Australia, will receive up to $10.7 million over five years from the National Institutes of Health (NIH) to move closer to identifying a vaccine candidate.
 

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